Instruments by Science Group
Macromolecular
Soft Condensed 
Imaging and
Biological
Magnetic
Structures and
Crystallography 
Spectroscopy I24 Contact
Beamline Phone Number:
+44 (0) 1235 778950
Principal Beamline Scientist:
Robin Owen
Tel: +44 (0) 1235 778522
E-mail: [email protected]
Science Group Leader
Dave Hall
Email: [email protected]
Tel: +44 (0) 1235 778926
I24 Microfocus MX
Status: Operational
Beamsize: 5x5 - 50x40 (variable aspect ratio)
Detector: Pilatus3 6M
Wavelength: 0.62Å - 1.77Å
Detector: Pilatus3 6M
Wavelength: 0.62Å - 1.77Å
These publications are based on data gathered on beamline I24. If you are aware of any errors or publications that should be listed here, please send details to [email protected].
89 items found for 2024 [total: 1243]
Unveiling the GT114 family: Structural characterization of A075L , a glycosyltransferase from Paramecium bursaria chlorella virus‐1 (PBCV ‐1) Protein Science, 33 Dec 2024 DOI: 10.1002/pro.5196
Discovery of MDI-114215: a potent and selective LIMK inhibitor to treat fragile X syndrome Journal Of Medicinal Chemistry, Dec 2024 DOI: 10.1021/acs.jmedchem.4c02694
Exchange, promiscuity, and orthogonality in de novo designed coiled-coil peptide assemblies Chemical Science, Dec 2024 DOI: 10.1039/D4SC06329E
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Specific radiation damage to halogenated inhibitors and ligands in protein–ligand crystal structures Journal Of Applied Crystallography, 57 Dec 2024 DOI: 10.1107/S1600576724010549
Structural studies of Von Willebrand factor regulators for thrombotic thrombocytopenic purpura Dec 2024
Thesis I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography
Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota Nature Communications, 15 Dec 2024 DOI: 10.1038/s41467-024-55268-w
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor Nature Communications, 15 Dec 2024 DOI: 10.1038/s41467-024-55381-w
Decoding the molecular basis of the specificity of an anti-sTn antibody Jacs Au, 48 Dec 2024 DOI: 10.1021/jacsau.4c00921
Design and evaluation of pyridinyl sulfonyl piperazine LpxH Inhibitors with potent antibiotic activity against enterobacterales Jacs Au, Nov 2024 DOI: 10.1021/jacsau.4c00731
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Structural and spectroscopic investigations of pH-dependent Mo(V) species in a bacterial sulfite-oxidizing enzyme Inorganic Chemistry, Nov 2024 DOI: 10.1021/acs.inorgchem.4c02584
Journal Paper I24-Microfocus Macromolecular Crystallography
Tethered heme domains in a triheme cytochrome allow for increased electron transport distances Protein Science, 33 Nov 2024 DOI: 10.1002/pro.5200
Journal Paper B21-High Throughput SAXS I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
The crystal structure of human IgD-Fc reveals unexpected differences with other antibody isotypes Proteins: Structure, Function, And Bioinformatics, 125 Nov 2024 DOI: 10.1002/prot.26771
Advancements in NMDA receptor-targeted antidepressants: from d-cycloserine discovery to preclinical efficacy of Lu AF90103 Journal Of Medicinal Chemistry, 67 Nov 2024 DOI: 10.1021/acs.jmedchem.4c01477
Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography
Processing serial synchrotron crystallography diffraction data with DIALS Nov 2024 DOI: 10.1016/bs.mie.2024.10.004
Book Chapter I24-Microfocus Macromolecular Crystallography
Structural requirements for the specific binding of CRABP2 to cyclin D3 Structure, 173 Oct 2024 DOI: 10.1016/j.str.2024.09.020
Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
A bacterial immunity protein directly senses two disparate phage proteins Nature, 18 Oct 2024 DOI: 10.1038/s41586-024-08039-y
Structural mechanisms of SLF1 interactions with Histone H4 and RAD18 at the stalled replication fork Nucleic Acids Research, 461 Oct 2024 DOI: 10.1093/nar/gkae831
Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders Nature Communications, 15 Oct 2024 DOI: 10.1038/s41467-024-52871-9
Journal Paper B21-High Throughput SAXS I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Structural and biochemical analysis of ligand binding in yeast Niemann-Pick type C1-related protein Life Science Alliance, 8 Oct 2024 DOI: 10.26508/lsa.202402990
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Fossil and present-day stromatolite ooids contain a meteoritic polymer of glycine and iron International Journal Of Astrobiology, 23 Oct 2024 DOI: 10.1017/S1473550424000168
Journal Paper B22-Multimode InfraRed imaging And Microspectroscopy I24-Microfocus Macromolecular Crystallography open access
Structural insight into rabies virus neutralization revealed by an engineered antibody scaffold Structure, 161 Oct 2024 DOI: 10.1016/j.str.2024.10.002
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Multiplexing methods in dynamic protein crystallography Oct 2024 DOI: 10.1016/bs.mie.2024.10.009
Book Chapter I24-Microfocus Macromolecular Crystallography
Human prolyl hydroxylase domain 2 reacts with O2 and 2-oxoglutarate to enable formation of inactive Fe(III).2OG.hypoxia-inducible-factor α complexes Scientific Reports, 14 Oct 2024 DOI: 10.1038/s41598-024-75761-y
Structural basis for the rescue of hyperexcitable cells by the amyotrophic lateral sclerosis drug Riluzole Nature Communications, 15 Sept 2024 DOI: 10.1038/s41467-024-52539-4
Journal Paper I04-Macromolecular Crystallography I23-Long wavelength MX I24-Microfocus Macromolecular Crystallography open access
Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5 Embo Molecular Medicine, 178 Sept 2024 DOI: 10.1038/s44321-024-00123-0
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
PLK1-mediated phosphorylation cascade activates Mis18 complex to ensure centromere inheritance Science, 385 Sept 2024 DOI: 10.1126/science.ado8270
Targeting cancer with small-molecule pan-KRAS degraders Science, 385 Sept 2024 DOI: 10.1126/science.adm8684
Journal Paper I24-Microfocus Macromolecular Crystallography
Expanding the inhibitor space of the WWP1 and WWP2 HECT E3 ligases Journal Of Enzyme Inhibition And Medicinal Chemistry, 39 Sept 2024 DOI: 10.1080/14756366.2024.2394895
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins Nature Communications, 15 Sept 2024 DOI: 10.1038/s41467-024-51934-1
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Exploring serial crystallography for drug discovery Iucrj, 11 Sept 2024 DOI: 10.1107/S2052252524006134
Selective Aurora A-TPX2 interaction inhibitors have in vivo efficacy as targeted antimitotic agents Journal Of Medicinal Chemistry, 9 Aug 2024 DOI: 10.1021/acs.jmedchem.4c01165
Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access
Genetic code expansion in Shewanella oneidensis MR-1 allows site-specific incorporation of bioorthogonal functional groups into a c-type cytochrome Acs Synthetic Biology, Aug 2024 DOI: 10.1021/acssynbio.4c00248
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
A BTB extension and ion-binding domain contribute to the pentameric structure and TFAP2A binding of KCTD1 Structure, 35 Aug 2024 DOI: 10.1016/j.str.2024.07.023
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Galectin-8N-selective 4-halophenylphthalazinone-galactals double π-stack in a unique pocket Acs Medicinal Chemistry Letters, 15 Aug 2024 DOI: 10.1021/acsmedchemlett.4c00212
Accelerated discovery of carbamate Cbl-b Inhibitors using generative AI models and structure-based drug design Journal Of Medicinal Chemistry, Aug 2024 DOI: 10.1021/acs.jmedchem.4c01034
Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence Nature Communications, 15 Aug 2024 DOI: 10.1038/s41467-024-51629-7
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Practical perspectives and roles of XRD in drug discovery: a review Current Analytical Chemistry, 20 Aug 2024 DOI: 10.2174/0115734110296435240323113938
Journal Paper I24-Microfocus Macromolecular Crystallography
Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition Nature Communications, 15 Jul 2024 DOI: 10.1038/s41467-024-50565-w
CRTAC1 has a compact β-propeller–TTR core stabilized by potassium ions Journal Of Molecular Biology, 26 Jul 2024 DOI: 10.1016/j.jmb.2024.168712
Activation of the canononical NF-kB pathway by the Kaposi's sarcoma-associated herpes virus oncoprotein vFLIP Jul 2024
Thesis I24-Microfocus Macromolecular Crystallography
Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5 Cell, 387 Jul 2024 DOI: 10.1016/j.cell.2024.06.037
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Delineation of the complete reaction cycle of a natural Diels–Alderase Chemical Science, 15 Jul 2024 DOI: 10.1039/D4SC02908A
Allosteric nanobodies to study the interactions between SOS1 and RAS Nature Communications, 15 Jul 2024 DOI: 10.1038/s41467-024-50349-2
Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype Cell, 24 Jul 2024 DOI: 10.1016/j.cell.2024.06.015
Journal Paper I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Molecular basis for pH sensing in the KDEL trafficking receptor Structure, 32 Jul 2024 DOI: 10.1016/j.str.2024.03.013
Structural mechanism underlying variations in DNA binding by the androgen receptor The Journal Of Steroid Biochemistry And Molecular Biology, 241 Jul 2024 DOI: 10.1016/j.jsbmb.2024.106499
Identification of innovative folate inhibitors leveraging the amino dihydrotriazine motif from cycloguanil for their potential as anti-Trypanosoma brucei agents Acs Infectious Diseases, 27 Jul 2024 DOI: 10.1021/acsinfecdis.4c00113
Spectroscopically validated pH-dependent MSOX movies provide detailed mechanism of copper nitrite reductases Journal Of Molecular Biology, 46 Jul 2024 DOI: 10.1016/j.jmb.2024.168706
Transition transferases prime bacterial capsule polymerization Nature Chemical Biology, 74 Jul 2024 DOI: 10.1038/s41589-024-01664-8
Exploring the effects of redox within the bacterial biofilm lifecycle of Pseudomonas aeruginosa - the importance of sensory domains June 2024
Thesis I03-Macromolecular Crystallography I04-Macromolecular Crystallography I23-Long wavelength MX I24-Microfocus Macromolecular Crystallography VMXi-Versatile Macromolecular Crystallography in situ
Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2 Open Biology, 14 June 2024 DOI: 10.1098/rsob.230252
Journal Paper I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Structural basis for recognition of the FLAG-tag by anti-FLAG M2 Journal Of Molecular Biology, 49 June 2024 DOI: 10.1016/j.jmb.2024.168649
Molecular mechanism of BMP signal control by Twisted gastrulation Nature Communications, 15 June 2024 DOI: 10.1038/s41467-024-49065-8
Journal Paper I03-Macromolecular Crystallography I23-Long wavelength MX I24-Microfocus Macromolecular Crystallography open access
Exploring the sequence-function space of microbial fucosidases Communications Chemistry, 7 June 2024 DOI: 10.1038/s42004-024-01212-4
Journal Paper I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinity Bioorganic & Medicinal Chemistry Letters, 21 June 2024 DOI: 10.1016/j.bmcl.2024.129861
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
A fragment based competitive 19F LB‐NMR platform for hotspot directed ligand profiling Angewandte Chemie International Edition, June 2024 DOI: 10.1002/anie.202406846
Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Mechanisms of neutralization of toxSAS from toxin–antitoxin modules Nature Chemical Biology, 6 June 2024 DOI: 10.1038/s41589-024-01630-4
Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity Cell Host & Microbe, 32 June 2024 DOI: 10.1016/j.chom.2024.04.012
Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design Structure, 63 June 2024 DOI: 10.1016/j.str.2024.05.011
Journal Paper I24-Microfocus Macromolecular Crystallography
Broad protection against invasive fungal disease from a nanobody targeting the active site of fungal b‐1,3‐glucanosyltransferases Angewandte Chemie International Edition, June 2024 DOI: 10.1002/anie.202405823
Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access
Structural descriptions of ligand interactions to RNA quadruplexes folded from the non-coding region of Pseudorabies virus Biochimie, 49 June 2024 DOI: 10.1016/j.biochi.2024.06.003
Rationally seeded computational protein design of ɑ-helical barrels Nature Chemical Biology, 53 June 2024 DOI: 10.1038/s41589-024-01642-0
Journal Paper B21-High Throughput SAXS I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Serial and time-resolved crystallography of metalloproteins June 2024
Thesis I24-Microfocus Macromolecular Crystallography
Biophysical and structural analyses of the interaction between the SHANK1 PDZ domain and an internal SLiM Biochemical Journal, June 2024 DOI: 10.1042/BCJ20240126
Retromer‐mediated recruitment of the WASH complex involves discrete interactions between VPS35 , VPS29, and FAM21 Protein Science, 33 May 2024 DOI: 10.1002/pro.4980
70 years in the making: a historical virus sample reveals a novel protein structure May 2024
Science Highlight I24-Microfocus Macromolecular Crystallography VMXm-Versatile Macromolecular Crystallography microfocus
Cobalamin decyanation by the membrane transporter BtuM Structure, 13 May 2024 DOI: 10.1016/j.str.2024.04.014
Journal Paper I24-Microfocus Macromolecular Crystallography
Structural and spectroscopic characterisation of Cytochrome c’ and Cytochrome P460 from Methylococcus capsulatus May 2024
Thesis I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation Nature Communications, 15 May 2024 DOI: 10.1038/s41467-024-48536-2
Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement Scientific Reports, 14 May 2024 DOI: 10.1038/s41598-024-62903-5
Novel dihydropteridinone derivatives as potent inhibitors of the understudied human kinases vaccinia-related kinase 1 and casein kinase 1δ/ε Journal Of Medicinal Chemistry, May 2024 DOI: 10.1021/acs.jmedchem.3c02250
Journal Paper I24-Microfocus Macromolecular Crystallography
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response Proceedings Of The National Academy Of Sciences, 121 Apr 2024 DOI: 10.1073/pnas.2320013121
An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin Communications Chemistry, 7 Apr 2024 DOI: 10.1038/s42004-024-01163-w
Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division Nature Microbiology, 9 Mar 2024 DOI: 10.1038/s41564-024-01600-5
Journal Paper I24-Microfocus Macromolecular Crystallography
Revisiting strategies and their combinatorial effect for introducing peroxygenase activity in CYP102A1 (P450BM3) Molecular Catalysis, 557 Mar 2024 DOI: 10.1016/j.mcat.2024.113953
Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from Prochlorococcus Proceedings Of The National Academy Of Sciences, 121 Mar 2024 DOI: 10.1073/pnas.2308478121
Structural dissection of two redox proteins from the shipworm symbiont Teredinibacter turnerae Iucrj, 11 Mar 2024 DOI: 10.1107/S2052252524001386
Journal Paper I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry–based de novo sequencing Life Science Alliance, 7 Mar 2024 DOI: 10.26508/lsa.202302366
7.10 MAG. a novel host monoacylglyceride for in meso (lipid cubic phase) crystallization of membrane proteins Crystal Growth & Design, 63 Mar 2024 DOI: 10.1021/acs.cgd.4c00087
Structure and function of Semaphorin-5A glycosaminoglycan interactions Nature Communications, 15 Mar 2024 DOI: 10.1038/s41467-024-46725-7
Journal Paper I03-Macromolecular Crystallography I23-Long wavelength MX I24-Microfocus Macromolecular Crystallography open access
Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2 Structure, 44 Feb 2024 DOI: 10.1016/j.str.2024.01.005
Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Human 2´-deoxynucleoside 5´-phosphate N-Hydrolase 1: the catalytic roles of Tyr24 and Asp80 Chembiochem, Feb 2024 DOI: 10.1002/cbic.202400047
Journal Paper I24-Microfocus Macromolecular Crystallography
Rational design of a cyclohexanone dehydrogenase for enhanced α, β-desaturation and substrate specificity Chemical Science, Feb 2024 DOI: 10.1039/D3SC04009G
Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access
UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4 Nature Structural & Molecular Biology, 116 Jan 2024 DOI: 10.1038/s41594-023-01192-4
Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access
Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases Embo Reports, 215 Jan 2024 DOI: 10.1038/s44319-023-00037-x
Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion Communications Biology, 7 Jan 2024 DOI: 10.1038/s42003-024-05794-6
Conformational activation and inhibition of von Willebrand factor by targeting its autoinhibitory module Blood Journal, Jan 2024 DOI: 10.1182/blood.2023022038
Journal Paper I24-Microfocus Macromolecular Crystallography
Using BpyAla to generate copper artificial metalloenzymes: a catalytic and structural study Catalysis Science & Technology, 24 Jan 2024 DOI: 10.1039/D3CY01648J
Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
- Maria Elena Laugieri, Immacolata Speciale, Ana Gimeno, Sicheng Lin, Brock W. Byers, Ana Poveda, Reyes Núñez‐franco, Idoia Iturrioz, María J. Moure, Gonzalo Jiménez-Osés, Irene Russo‐krauss, Anna Notaro, James L. Van Etten, Todd L. Lowary, Jesús Jimenez-Barbero, Cristina De Castro, Michela Tonetti, Adriana L. Rojas, "Unveiling the GT114 family: Structural characterization of A075L , a glycosyltransferase from Paramecium bursaria chlorella virus‐1 (PBCV ‐1)", Protein Science, 33 (2024), DOI: 10.1002/pro.5196
- Alex G. Baldwin, David W. Foley, Ross Collins, Hyunah Lee, D. Heulyn Jones, Ben Wahab, Loren Waters, Josephine Pedder, Marie Paine, Gui Jie Feng, Lucia Privitera, Alexander Ashall-Kelly, Carys Thomas, Jason A. Gillespie, Lauramariú Schino, Delia Belelli, Cecilia Rocha, Gilles Maussion, Andrea I. Krahn, Thomas M. Durcan, Jonathan M. Elkins, Jeremy J. Lambert, John R. Atack, Simon E. Ward, "Discovery of MDI-114215: a potent and selective LIMK inhibitor to treat fragile X syndrome", Journal Of Medicinal Chemistry (2024), DOI: 10.1021/acs.jmedchem.4c02694
- Kathleen W. Kurgan, Freddie J. O. Martin, William M. Dawson, Thomas Brunnock, Andrew Orr-Ewing, Derek Woolfson, "Exchange, promiscuity, and orthogonality in de novo designed coiled-coil peptide assemblies", Chemical Science (2024), DOI: 10.1039/D4SC06329E
- Matthew Rodrigues, Marc Cabry, Gavin Collie, Michael Carter, Craig Mcandrew, Robin L. Owen, Benjamin R. Bellenie, Yann-Vai Le Bihan, Rob L. M. Van Montfort, "Specific radiation damage to halogenated inhibitors and ligands in protein–ligand crystal structures", Journal Of Applied Crystallography, 57, 1951 - 1965 (2024), DOI: 10.1107/S1600576724010549
- [Thesis] Zoe J. Markham-Lee, "Structural studies of Von Willebrand factor regulators for thrombotic thrombocytopenic purpura" (2024)
- Carla Pérez-Cruz, Alicia Moraleda-Montoya, Raquel Liébana, Oihana Terrones, Uxue Arrizabalaga, Mikel Garcia-Alija, Maier Lorizate, Ana Martínez Gascueña, Isabel García-Álvarez, Jon Ander Nieto-Garai, June Olazar-Intxausti, Bárbara Rodríguez-Colinas, Enrique Mann, José Luis Chiara, Francesc-Xabier Contreras, Marcelo E. Guerin, Beatriz Trastoy, Laura Alonso-Sáez, "Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-55268-w
- Thomas L. Williams, Gregory Verdon, Rhoda E. Kuc, Heather Currinn, Brian Bender, Nicolae Solcan, Oliver Schlenker, Robyn G. C. Macrae, Jason Brown, Marco Schütz, Andrei Zhukov, Sanjay Sinha, Chris De Graaf, Stefan Graf, Janet J. Maguire, Alastair J. H. Brown, Anthony P. Davenport, "Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-55381-w
- Cátia O. Soares, Maria Elena Laugieri, Ana Sofia Grosso, Mariangela Natale, Helena Coelho, Sandra Behren, Jin Yu, Hui Cai, Antonio Franconetti, Iker Oyenarte, Maria Magnasco, Ana Gimeno, Nuno Ramos, Wengang Chai, Francisco Corzana, Ulrika Westerlind, Jesús Jiménez-Barbero, Angelina S. Palma, Paula A. Videira, June Ereño-Orbea, Filipa Marcelo, "Decoding the molecular basis of the specificity of an anti-sTn antibody", Jacs Au, 48 (2024), DOI: 10.1021/jacsau.4c00921
- Amanda F. Ennis, C. Skyler Cochrane, Patrick A. Dome, Pyeonghwa Jeong, Jincheng Yu, Hyejin Lee, Carly S. Williams, Yang Ha, Weitao Yang, Pei Zhou, Jiyong Hong, "Design and evaluation of pyridinyl sulfonyl piperazine LpxH Inhibitors with potent antibiotic activity against enterobacterales", Jacs Au (2024), DOI: 10.1021/jacsau.4c00731
- Ahmed Djeghader, Julia Rendon, Frédéric Biaso, Guillaume Gerbaud, Wolfgang Nitschke, Barbara Schoepp-Cothenet, Tewfik Soulimane, Stéphane Grimaldi, "Structural and spectroscopic investigations of pH-dependent Mo(V) species in a bacterial sulfite-oxidizing enzyme", Inorganic Chemistry (2024), DOI: 10.1021/acs.inorgchem.4c02584
- Benjamin W. Nash, Tomás M. Fernandes, Joshua A. J. Burton, Leonor Morgado, Jessica H. Van Wonderen, Dimitri A. Svistunenko, Marcus J. Edwards, Carlos A. Salgueiro, Julea N. Butt, Thomas A. Clarke, "Tethered heme domains in a triheme cytochrome allow for increased electron transport distances", Protein Science, 33 (2024), DOI: 10.1002/pro.5200
- Julie E. M. Mcgeoch, Malcolm W. Mcgeoch, "Sea foam contains hemoglycin from cosmic dust", Rsc Advances, 14, 36919 - 36929 (2024), DOI: 10.1039/D4RA06881E
- Anna M. Davies, Tam T. T. Bui, Raúl Pacheco‐gómez, Susan K. Vester, Andrew J. Beavil, Hannah J. Gould, Brian J. Sutton, James M. Mcdonnell, "The crystal structure of human IgD-Fc reveals unexpected differences with other antibody isotypes", Proteins: Structure, Function, And Bioinformatics, 125 (2024), DOI: 10.1002/prot.26771
- Erhad Ascic, Mauro Marigo, Laurent David, Kjartan Frisch Herrik, Morten Grupe, Charlotte Hougaard, Arne Mørk, Christopher R. Jones, Lassina Badolo, Kristen Frederiksen, Harrie C. M. Boonen, Henrik Sindal Jensen, John Paul Kilburn, "Advancements in NMDA receptor-targeted antidepressants: from d-cycloserine discovery to preclinical efficacy of Lu AF90103", Journal Of Medicinal Chemistry, 67, 20135 - 20155 (2024), DOI: 10.1021/acs.jmedchem.4c01477
- [Book Chapter] James Beilsten-Edmands, James M. Parkhurst, Graeme Winter, Gwyndaf Evans, "Processing serial synchrotron crystallography diffraction data with DIALS" (2024), DOI: 10.1016/bs.mie.2024.10.004
- Martyna W. Pastok, Charles W. E. Tomlinson, Shannon Turberville, Abbey M. Butler, Arnaud Basle, Martin E. M. Noble, Jane A. Endicott, Ehmke Pohl, Natalie J. Tatum, "Structural requirements for the specific binding of CRABP2 to cyclin D3", Structure, 173 (2024), DOI: 10.1016/j.str.2024.09.020
- Tong Zhang, Albinas Cepauskas, Anastasiia Nadieina, Aurelien Thureau, Kyo Coppieters 'T Wallant, Chloé Martens, Daniel C. Lim, Abel Garcia-Pino, Michael T. Laub, "A bacterial immunity protein directly senses two disparate phage proteins", Nature, 18 (2024), DOI: 10.1038/s41586-024-08039-y
- Emma I. Ryder, Nazia Nasir, Amy e. O. Durgan, Michael Jenkyn-Bedford, Stephanie Tye, Xiaodong Zhang, Qian Wu, "Structural mechanisms of SLF1 interactions with Histone H4 and RAD18 at the stalled replication fork", Nucleic Acids Research, 461 (2024), DOI: 10.1093/nar/gkae831
- Alena Kroupova, Valentina A. Spiteri, Zoe J. Rutter, Hirotake Furihata, Darren Darren, Sarath Ramachandran, Sohini Chakraborti, Kevin Haubrich, Julie Pethe, Denzel Gonzales, Andre J. Wijaya, Maria Rodriguez-Rios, Manon Sturbaut, Dylan M. Lynch, William Farnaby, Mark A. Nakasone, David Zollman, Alessio Ciulli, "Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-52871-9
- Lynette Nel, Katja Thaysen, Denisa Jamecna, Esben Olesen, Maria Szomek, Julia Langer, Kelly M. Frain, Doris Höglinger, Daniel Wüstner, Bjørn P. Pedersen, "Structural and biochemical analysis of ligand binding in yeast Niemann-Pick type C1-related protein", Life Science Alliance, 8 (2024), DOI: 10.26508/lsa.202402990
- Julie E. M. Mcgeoch, Anton Frommelt, Robin L. Owen, Gianfelice Cinque, Arthur Mcclelland, David Lageson, Malcolm W. Mcgeoch, "Fossil and present-day stromatolite ooids contain a meteoritic polymer of glycine and iron", International Journal Of Astrobiology, 23 (2024), DOI: 10.1017/S1473550424000168
- Ashwini Kedari, Rommel Iheozor-Ejiofor, Petja Salminen, Hasan Uğurlu, Anna R. Mäkelä, Lev Levanov, Olli Vapalahti, Vesa P. Hytönen, Kalle Saksela, Ilona Rissanen, "Structural insight into rabies virus neutralization revealed by an engineered antibody scaffold", Structure, 161 (2024), DOI: 10.1016/j.str.2024.10.002
- [Book Chapter] Margaret A. Klureza, Yelyzaveta Pulnova, David Von Stetten, Robin L. Owen, Godfrey S. Beddard, Arwen R. Pearson, Briony A. Yorke, "Multiplexing methods in dynamic protein crystallography" (2024), DOI: 10.1016/bs.mie.2024.10.009
- Giorgia Fiorini, Stephen A. Marshall, William D. Figg, William K. Myers, Lennart Brewitz, Christopher J. Schofield, "Human prolyl hydroxylase domain 2 reacts with O2 and 2-oxoglutarate to enable formation of inactive Fe(III).2OG.hypoxia-inducible-factor α complexes", Scientific Reports, 14 (2024), DOI: 10.1038/s41598-024-75761-y
- David Hollingworth, Frances Thomas, Dana A. Page, Mohamed A. Fouda, Raquel Lopez-Rios De Castro, Altin Sula, Vitaliy B. Mykhaylyk, Geoff Kelly, Martin B. Ulmschneider, Peter C. Ruben, Bonnie A. Wallace, "Structural basis for the rescue of hyperexcitable cells by the amyotrophic lateral sclerosis drug Riluzole", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-52539-4
- Thomas E. Harrison, Nawsad Alam, Brendan Farrell, Doris Quinkert, Amelia M. Lias, Lloyd D. W. King, Lea K. Barfod, Simon J. Draper, Ivan Campeotto, Matthew K. Higgins, "Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5", Embo Molecular Medicine, 178 (2024), DOI: 10.1038/s44321-024-00123-0
- Pragya Parashara, Bethan Medina-Pritchard, Maria Alba Abad, Paula Sotelo-Parrilla, Reshma Thamkachy, David Grundei, Juan Zou, Christos Spanos, Chandni Natalia Kumar, Claire Basquin, Vimal Das, Zhaoyue Yan, Asma Abdullah Al-Murtadha, David A. Kelly, Toni Mchugh, Axel Imhof, Juri Rappsilber, A. Arockia Jeyaprakash, "PLK1-mediated phosphorylation cascade activates Mis18 complex to ensure centromere inheritance", Science, 385, 1098 - 1104 (2024), DOI: 10.1126/science.ado8270
- Johannes Popow, William Farnaby, Andreas Gollner, Christiane Kofink, Gerhard Fischer, Melanie Wurm, David Zollman, Andre Wijaya, Nikolai Mischerikow, Carina Hasenoehrl, Polina Prokofeva, Heribert Arnhof, Silvia Arce-Solano, Sammy Bell, Georg Boeck, Emelyne Diers, Aileen B. Frost, Jake Goodwin-Tindall, Jale Karolyi-Oezguer, Shakil Khan, Theresa Klawatsch, Manfred Koegl, Roland Kousek, Barbara Kratochvil, Katrin Kropatsch, Arnel A. Lauber, Ross Mclennan, Sabine Olt, Daniel Peter, Oliver Petermann, Vanessa Roessler, Peggy Stolt-Bergner, Patrick Strack, Eva Strauss, Nicole Trainor, Vesna Vetma, Claire Whitworth, Siying Zhong, Jens Quant, Harald Weinstabl, Bernhard Kuster, Peter Ettmayer, Alessio Ciulli, "Targeting cancer with small-molecule pan-KRAS degraders", Science, 385, 1338 - 1347 (2024), DOI: 10.1126/science.adm8684
- Ashley P. Dudey, Jake M. Rigby, Gregory R. Hughes, G. Richard Stephenson, Thomas E. Storr, Andrew Chantry, Andrew M. Hemmings, "Expanding the inhibitor space of the WWP1 and WWP2 HECT E3 ligases", Journal Of Enzyme Inhibition And Medicinal Chemistry, 39 (2024), DOI: 10.1080/14756366.2024.2394895
- Tom J. Arrowsmith, Xibing Xu, Shangze Xu, Ben Usher, Peter Stokes, Megan Guest, Agnieszka K. Bronowska, Pierre Genevaux, Tim R. Blower, "Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-51934-1
- A. Dunge, C. Phan, O. Uwangue, M. Bjelcic, J. Gunnarsson, G. Wehlander, H. Käck, G. Branden, "Exploring serial crystallography for drug discovery", Iucrj, 11, 831 - 842 (2024), DOI: 10.1107/S2052252524006134
- Simon R. Stockwell, Duncan E. Scott, Gerhard Fischer, Estrella Guarino, Timothy P. C. Rooney, Tzu-Shean Feng, Tommaso Moschetti, Rajavel Srinivasan, Esther Alza, Alice Asteian, Claudio Dagostin, Anna Alcaide, Mathieu Rocaboy, Beata Blaszczyk, Alicia Higueruelo, Xuelu Wang, Maxim Rossmann, Trevor R. Perrior, Tom L. Blundell, David R. Spring, Grahame Mckenzie, Chris Abell, John Skidmore, Ashok R. Venkitaraman, Marko Hyvonen, "Selective Aurora A-TPX2 interaction inhibitors have in vivo efficacy as targeted antimitotic agents", Journal Of Medicinal Chemistry, 9 (2024), DOI: 10.1021/acs.jmedchem.4c01165
- Colin W. J. Lockwood, Benjamin W. Nash, Simone E. Newton-Payne, Jessica H. Van Wonderen, Keir P. S. Whiting, Abigail Connolly, Alexander L. Sutton-Cook, Archie Crook, Advait R. Aithal, Marcus J. Edwards, Thomas A. Clarke, Amit Sachdeva, Julea N. Butt, "Genetic code expansion in Shewanella oneidensis MR-1 allows site-specific incorporation of bioorthogonal functional groups into a c-type cytochrome", Acs Synthetic Biology (2024), DOI: 10.1021/acssynbio.4c00248
- Daniel M. Pinkas, Joshua C. Bufton, Alice E. Hunt, Charlotte E. Manning, William Richardson, Alex N. Bullock, "A BTB extension and ion-binding domain contribute to the pentameric structure and TFAP2A binding of KCTD1", Structure, 35 (2024), DOI: 10.1016/j.str.2024.07.023
- Sjors Van Klaveren, Mujtaba Hassan, Maria Håkansson, Richard E. Johnsson, Jessica Larsson, Žiga Jakopin, Marko Anderluh, Hakon Leffler, Tihomir Tomašič, Ulf J. Nilsson, "Galectin-8N-selective 4-halophenylphthalazinone-galactals double π-stack in a unique pocket", Acs Medicinal Chemistry Letters, 15, 1319 - 1324 (2024), DOI: 10.1021/acsmedchemlett.4c00212
- Taylor R. Quinn, Kathryn A. Giblin, Clare Thomson, Jeffrey A. Boerth, Gayathri Bommakanti, Erin Braybrooke, Christina Chan, Alex J. Chinn, Erin Code, Caifeng Cui, Yukai Fan, Neil P. Grimster, Keishi Kohara, Michelle L. Lamb, Lina Ma, Adelphe M. Mfuh, Graeme R. Robb, Kevin J. Robbins, Marianne Schimpl, Haoran Tang, Jamie Ware, Gail L. Wrigley, Lin Xue, Yun Zhang, Huimin Zhu, Samantha J. Hughes, "Accelerated discovery of carbamate Cbl-b Inhibitors using generative AI models and structure-based drug design", Journal Of Medicinal Chemistry (2024), DOI: 10.1021/acs.jmedchem.4c01034
- Sam C. Went, David M. Picton, Richard D. Morgan, Andrew Nelson, Aisling Brady, Giuseppina Mariano, David T. F. Dryden, Darren L. Smith, Nicolas Wenner, Jay C. D. Hinton, Tim R. Blower, "Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-51629-7
- Ashish Mehta, Rahul Makhija, Pallavi Barik, Shubham Dhiman, Ghanshyam Das Gupta, Vivek Asati, "Practical perspectives and roles of XRD in drug discovery: a review", Current Analytical Chemistry, 20, 449 - 470 (2024), DOI: 10.2174/0115734110296435240323113938
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- J. Wouter Beugelink, Henrietta Hóf, Bert J. C. Janssen, "CRTAC1 has a compact β-propeller–TTR core stabilized by potassium ions", Journal Of Molecular Biology, 26 (2024), DOI: 10.1016/j.jmb.2024.168712
- [Thesis] Swathi Lakshmi Senthil Kumar, "Activation of the canononical NF-kB pathway by the Kaposi's sarcoma-associated herpes virus oncoprotein vFLIP" (2024)
- Lawrence T. Wang, Andrew J. R. Cooper, Brendan Farrell, Kazutoyo Miura, Ababacar Diouf, Nicole Müller-Sienerth, Cécile Crosnier, Lauren Purser, Payton J. Kirtley, Maciej Maciuszek, Jordan R. Barrett, Kirsty Mchugh, Rodney Ogwang, Courtney Tucker, Shanping Li, Safiatou Doumbo, Didier Doumtabe, Chul-Woo Pyo, Jeff Skinner, Carolyn M. Nielsen, Sarah E. Silk, Kassoum Kayentao, Aissata Ongoiba, Ming Zhao, Doan C. Nguyen, F. Eun-Hyung Lee, Angela M. Minassian, Daniel E. Geraghty, Boubacar Traore, Robert A. Seder, Brandon K. Wilder, Peter D. Crompton, Gavin J. Wright, Carole A. Long, Simon J. Draper, Matthew K. Higgins, Joshua Tan, "Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5", Cell, 387 (2024), DOI: 10.1016/j.cell.2024.06.037
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- Baptiste Fischer, Tomasz Uchanski, Aidana Sheryazdanova, Simon Gonzalez, Alexander N. Volkov, Elke Brosens, Thomas Zogg, Valentina Kalichuk, Steven Ballet, Wim Versees, Anna A. Sablina, Els Pardon, Alexandre Wohlkonig, Jan Steyaert, "Allosteric nanobodies to study the interactions between SOS1 and RAS", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-50349-2
- Jordan R. Barrett, Dimitra Pipini, Nathan D. Wright, Andrew J. R. Cooper, Giacomo Gorini, Doris Quinkert, Amelia M. Lias, Hannah Davies, Cassandra A. Rigby, Maya Aleshnick, Barnabas G. Williams, William J. Bradshaw, Neil G. Paterson, Thomas Martinson, Payton Kirtley, Luc Picard, Christine D. Wiggins, Francesca R. Donnellan, Lloyd D. W. King, Lawrence T. Wang, Jonathan F. Popplewell, Sarah E. Silk, Jed De Ruiter Swain, Katherine Skinner, Vinayaka Kotraiah, Amy R. Noe, Randall S. Macgill, C. Richter King, Ashley J. Birkett, Lorraine A. Soisson, Angela M. Minassian, Douglas A. Lauffenburger, Kazutoyo Miura, Carole A. Long, Brandon K. Wilder, Lizbe Koekemoer, Joshua Tan, Carolyn M. Nielsen, Kirsty Mchugh, Simon J. Draper, "Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype", Cell, 24 (2024), DOI: 10.1016/j.cell.2024.06.015
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- Xiao Yin Lee, Wout Van Eynde, Christine Helsen, Hanne Willems, Kaat Peperstraete, Sofie De Block, Arnout Voet, Frank Claessens, "Structural mechanism underlying variations in DNA binding by the androgen receptor", The Journal Of Steroid Biochemistry And Molecular Biology, 241 (2024), DOI: 10.1016/j.jsbmb.2024.106499
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- Samuel L. Rose, Felix Martin Ferroni, Sam Horrell, Carlos Dante Brondino, Robert R. Eady, Sofia Jaho, Michael A. Hough, Robin L. Owen, Svetlana V. Antonyuk, S. Samar Hasnain, "Spectroscopically validated pH-dependent MSOX movies provide detailed mechanism of copper nitrite reductases", Journal Of Molecular Biology, 46 (2024), DOI: 10.1016/j.jmb.2024.168706
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- [Thesis] Charlotte R. Cordery, "Exploring the effects of redox within the bacterial biofilm lifecycle of Pseudomonas aeruginosa - the importance of sensory domains" (2024)
- Katy Cornish, Jiandong Huo, Luke Jones, Parul Sharma, Joseph W. Thrush, Sahar Abdelkarim, Anja Kipar, Siva Ramadurai, Miriam Weckener, Halina Mikolajek, Sai Liu, Imogen Buckle, Eleanor Bentley, Adam Kirby, Ximeng Han, Stephen M. Laidlaw, Michelle Hill, Lauren Eyssen, Chelsea Norman, Audrey Le Bas, John Clarke, William James, James P. Stewart, Miles Carroll, James Naismith, Raymond J. Owens, "Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2", Open Biology, 14 (2024), DOI: 10.1098/rsob.230252
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- Ana Martínez Gascueña, Haiyang Wu, Rui Wang, C. David Owen, Pedro J. Hernando, Serena Monaco, Matthew Penner, Ke Xing, Gwenaelle Le Gall, Richard Gardner, Didier Ndeh, Paulina A. Urbanowicz, Daniel I. R. Spencer, Martin Walsh, Jesus Angulo, Nathalie Juge, "Exploring the sequence-function space of microbial fucosidases", Communications Chemistry, 7 (2024), DOI: 10.1038/s42004-024-01212-4
- Martina Pierri, Xingui Liu, Alena Kroupova, Zoe Rutter, Alex J. Hallatt, Alessio Ciulli, "Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinity", Bioorganic & Medicinal Chemistry Letters, 21 (2024), DOI: 10.1016/j.bmcl.2024.129861
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- Lucia Dominguez-Molina, Tatsuaki Kurata, Albinas Cepauskas, Dannele Echemendia-Blanco, Safia Zedek, Ariel Talavera-Perez, Gemma C. Atkinson, Vasili Hauryliuk, Abel Garcia-Pino, "Mechanisms of neutralization of toxSAS from toxin–antitoxin modules", Nature Chemical Biology, 6 (2024), DOI: 10.1038/s41589-024-01630-4
- Magdalena Szczesna, Yizhou Huang, Rachel E. Lacoursiere, Francesca Bonini, Vito Pol, Fulya Koc, Beatrice Ward, Paul P. Geurink, Jonathan N. Pruneda, Teresa L. M. Thurston, "Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity", Cell Host & Microbe, 32, 913 - 924.e7 (2024), DOI: 10.1016/j.chom.2024.04.012
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- Sergio Redrado-Hernández, Javier Macías-León, Jorge Castro-López, Ana Belén Sanz, Elena Dolader, Maykel Arias, Andrés Manuel González-Ramírez, David Sánchez-Navarro, Yuliya Petryk, Vladimir Farkaš, Cecile Vincke, Serge Muyldermans, Irene García-Barbazán, Celia Del Agua, Oscar Zaragoza, Javier Arroyo, Julián Pardo, Eva Gálvez, Ramon Hurtado-Guerrero, "Broad protection against invasive fungal disease from a nanobody targeting the active site of fungal b‐1,3‐glucanosyltransferases", Angewandte Chemie International Edition (2024), DOI: 10.1002/anie.202405823
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- Katherine I. Albanese, Rokas Petrenas, Fabio Pirro, Elise A. Naudin, Ufuk Borucu, William M. Dawson, D. Arne Scott, Graham. J. Leggett, Orion D. Weiner, Thomas A. A. Oliver, Derek N. Woolfson, "Rationally seeded computational protein design of ɑ-helical barrels", Nature Chemical Biology, 53 (2024), DOI: 10.1038/s41589-024-01642-0
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- Yue Li, Chi H. Trinh, Amanda Acevedo-Jake, Diana Gimenez, Stuart L Warriner, Andrew J. Wilson, "Biophysical and structural analyses of the interaction between the SHANK1 PDZ domain and an internal SLiM", Biochemical Journal (2024), DOI: 10.1042/BCJ20240126
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- [Thesis] Hannah R. Adams, "Structural and spectroscopic characterisation of Cytochrome c’ and Cytochrome P460 from Methylococcus capsulatus" (2024)
- Karin E. J. Roedstroem, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H. M. Smith, Ashley C. W. Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R. Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J. Owens, Simon Newstead, Jan Steyaert, Elisabeth P. Carpenter, Stephen J. Tucker, "Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-48536-2
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- Fernando H. De Souza Gama, Luiz A. Dutra, Michael Hawgood, Caio Vinícius Dos Reis, Ricardo A. M. Serafim, Marcos A. Ferreira, Bruno V. M. Teodoro, Jéssica Emi Takarada, André S. Santiago, Dimitrios-Ilias Balourdas, Ann-Sofie Nilsson, Bruno Urien, Vitor M. Almeida, Carina Gileadi, Priscila Z. Ramos, Anita Salmazo, Stanley N. S. Vasconcelos, Micael R. Cunha, Susanne Mueller, Stefan Knapp, Katlin B. Massirer, Jonathan M. Elkins, Opher Gileadi, Alessandra Mascarello, Bennie B. L. G. Lemmens, Cristiano R. W. Guimarães, Hatylas Azevedo, Rafael M. Counago, "Novel dihydropteridinone derivatives as potent inhibitors of the understudied human kinases vaccinia-related kinase 1 and casein kinase 1δ/ε", Journal Of Medicinal Chemistry (2024), DOI: 10.1021/acs.jmedchem.3c02250
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- Phillip Nußbaum, Danguole Kureisaite-Ciziene, Dom Bellini, Chris Van Der Does, Marko Kojic, Najwa Taib, Anna Yeates, Maxime Tourte, Simonetta Gribaldo, Martin Loose, Jan Lowe, Sonja-Verena Albers, "Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division", Nature Microbiology, 9, 698 - 711 (2024), DOI: 10.1038/s41564-024-01600-5
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