Conformational plasticity at the IgE-binding site of the B-cell receptor CD23 Balvinder Dhaliwal, Marie O. Y. Pang, Daopeng Yuan, Norhakim Yahya, Stella Fabiane, James M. Mcdonnell, Hannah J. Gould, Andrew J. Beavil, Brian J. Sutton
Molecular Immunology, 56 (4) Dec 2013 DOI: 10.1016/j.molimm.2013.07.005 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies Kristin A. Sutton, Paul J. Black, Kermit R. Mercer, Elspeth F. Garman, Robin Owen, Edward Snell, William A. Bernhard
Acta Crystallographica Section D Biological Crystallography, 69 Dec 2013 DOI: 10.1107/S0907444913022117 Journal Paper I24-Microfocus Macromolecular Crystallography open access Crystal structure of a promoter sequence in the B-raf gene reveals an intertwined dimer quadruplex Dengguo Wei, Alan K. Todd, Mire Zloh, Mekala Gunaratnam, Gary Parkinson, Stephen Neidle
Journal Of The American Chemical Society, 135 (51) Dec 2013 DOI: 10.1021/ja4101358 Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation Miranda Lewis, C. J. Arnot, H. Beeston, A. Mccoy, A. E. Ashcroft, N. J. Gay, Monique Gangloff
Proceedings Of The National Academy Of Sciences, 110 (51) Dec 2013 DOI: 10.1073/pnas.1317002110 Journal Paper I24-Microfocus Macromolecular Crystallography open access Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay Gustavo A. Afanador, Stephen Muench, Martin Mcphillie, Alina Fomovska, Arne Schön, Ying Zhou, Gang Cheng, Jozef Stec, Joel S. Freundlich, Hong-Ming Shieh, John W. Anderson, David P. Jacobus, David A. Fidock, Alan P. Kozikowski, Colin W. Fishwick, David W. Rice, Ernesto Freire, Rima Mcleod, Sean T. Prigge
Biochemistry, 52 (51) Dec 2013 DOI: 10.1021/bi400945y Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre Domenico Bellini, Delphine L. Caly, Yvonne Mccarthy, Mario Bumann, Shi-Qi An, J. Maxwell Dow, Robert P. Ryan, Martin A. Walsh
Molecular Microbiology, Nov 2013 DOI: 10.1111/mmi.12447 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Structure and assembly of an inner membrane platform for initiation of type IV pilus biogenesis Vijaykumar Karuppiah, R. F. Collins, A. Thistlethwaite, Ya Gao, Jeremy P. Derrick
Proceedings Of The National Academy Of Sciences, Nov 2013 DOI: 10.1073/pnas.1312313110 Journal Paper I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin Matthias Zebisch, Yang Xu, Christos Krastev, Bryan T. Macdonald, Maorong Chen, Robert J. C. Gilbert, Xi He, Edith Jones
Nature Communications, 4 Nov 2013 DOI: 10.1038/ncomms3787 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access The molecular recognition of kink-turn structure by the L7Ae class of proteins Lin Huang, David Lilley
Rna, 19 (12) Nov 2013 DOI: 10.1261/rna.041517.113 Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Screening protein - Single stranded RNA complexes by NMR spectroscopy for structure determination Jaelle Foot, Mike Feracci, Cyril Dominguez
Methods, Oct 2013 DOI: 10.1016/j.ymeth.2013.09.018 Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access A structural and dynamic investigation of the inhibition of catalase by nitric oxide Marco Candelaresi, Andrea Gumiero, Katrin Adamczyk, Kirsty Robb, César Bellota-Antón, Vartul Sangal, John Munnoch, Gregory M. Greetham, Mike Towrie, Paul A. Hoskisson, Anthony W. Parker, Nicholas P. Tucker, Martin A. Walsh, Neil T. Hunt
Organic & Biomolecular Chemistry, 11 (44) Oct 2013 DOI: 10.1039/c3ob41977k Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Structural insights into WcbI, a novel polysaccharide-biosynthesis enzyme Mirella Vivoli, Emily Ayres, Edward Beaumont, Michail N. Isupov, Nicholas J. Harmer
Iucrj, 1 Oct 2013 DOI: 10.1107/S205225251302695X Journal Paper I02-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access On the catalytic mechanism of dimeric dUTPases Glyn Hemsworth, Dolores González-Pacanowska, Keith Wilson
Biochemical Journal, Sept 2013 DOI: 10.1042/BJ20130796 Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors Thomas L. Rodgers, Philip Townsend, David Burnell, Matthew L. Jones, Shane A. Richards, Tom C. B. Mcleish, Ehmke Pohl, Mark R. Wilson, Martin J. Cann
Plos Biology, 11 (9) Sept 2013 DOI: 10.1371/journal.pbio.1001651 Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access A two-domain elevator mechanism for sodium/proton antiport Chiara Lee, Haejoo Kang, Christoph Von Ballmoos, Simon Newstead, Povilas Uzdavinys, David L. Dotson, So Iwata, Oliver Beckstein, Alex Cameron, David Drew
Nature, Sept 2013 DOI: 10.1038/nature12484 Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography A novel allosteric inhibitor of the uridine diphosphate n-acetylglucosamine pyrophosphorylase from Trypanosoma brucei Michael D. Urbaniak, Iain T. Collie, Wenxia Fang, Tonia Aristotelous, Susanne Eskilsson, Olawale G. Raimi, Justin Harrison, Iva Hopkins Navratilova, Julie A. Frearson, Daan M. F. Van Aalten, Michael A. J. Ferguson
Acs Chemical Biology, 8 (9) Sept 2013 DOI: 10.1021/cb400411x Journal Paper I24-Microfocus Macromolecular Crystallography open access Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport Ivan Laponogov, Dennis A. Veselkov, Isabelle M.- T. Crevel, Xiao-Su Pan, L. Mark Fisher, Mark R. Sanderson
Nucleic Acids Research, Aug 2013 DOI: 10.1093/nar/gkt749 Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access The structure of the ternary complex of Krev Interaction Trapped 1 (KRIT1) bound to both the Rap1 GTPase and the Heart of Glass (HEG1) cytoplasmic tail Alexandre R. Gingras, Wilma Puzon-Mclaughlin, Mark H. Ginsberg
Journal Of Biological Chemistry, 288 (33) Aug 2013 DOI: 10.1074/jbc.M113.462911 Journal Paper I02-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Optimization of bimorph mirrors on x-ray synchrotron beamlines John Sutter, Simon Alcock, Kawal Sawhney
SPIE Newsroom, Aug 2013 DOI: 10.1117/2.1201308.005021 Magazine Article B16-Test Beamline I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography I19-Small Molecule Single Crystal Diffraction I22-Small angle scattering & Diffraction I24-Microfocus Macromolecular Crystallography The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle Nadia Arnaudo, Israel S. Fernandez, Stephen H. Mclaughlin, Sew Y. Peak-Chew, Daniela Rhodes, Fabrizio Martino
Nature Structural & Molecular Biology, Aug 2013 DOI: 10.1038/nsmb.2641 Tying down the arm in Bacillus dUTPase: structure and mechanism Javier García-Nafría, Jennifer Timm, Charlotte Harrison, Johan P. Turkenburg, Keith S. Wilson
Acta Crystallographica Section D Biological Crystallography, 69 Aug 2013 DOI: 10.1107/S090744491300735X Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography Binding of (5S)-penicilloic acid to penicillin binding protein 3 Sander S. Van Berkel, Joanne Nettleship, Ivanhoe K. H. Leung, Jurgen Brem, Hwanho Choi, David I. Stuart, Timothy D. W. Claridge, Michael A. Mcdonough, Raymond J. Owens, Jingshan Ren, Christopher J. Schofield
Acs Chemical Biology, 8 (10) Aug 2013 DOI: 10.1021/cb400200h Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography Multimeric complexes among ankyrin-repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: insights into the structure and assembly of ECS-type Cullin-RING E3 ubiquitin ligases Jemima C. Thomas, Dijana Matak-Vinkovic, Inge Van Molle, Alessio Ciulli
Biochemistry, 52 (31) Aug 2013 DOI: 10.1021/bi400758h Journal Paper I24-Microfocus Macromolecular Crystallography open access Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3 Hao Dou, Lori Buetow, Gary J Sibbet, Kenneth Cameron, Danny Huang
Nature Structural & Molecular Biology, 20 (8) Jul 2013 DOI: 10.1038/nsmb.2621 Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography James Foadi, Pierre Aller, Yilmaz Alguel, Alex Cameron, Danny Axford, Robin Owen, Wes Armour, David Waterman, So Iwata, Gwyndaf Evans
Acta Crystallographica Section D Biological Crystallography, 69 Jul 2013 DOI: 10.1107/S0907444913012274 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Micro-focused X-ray diffraction characterization of high-quality [6,6]-phenyl-C61-butyric acid methyl ester single crystals without solvent impurities Giuseppe Paternò, Jacob Spencer, Gwyndaf Evans, Victoria García Sakai, Jochen Blumberger, Franco Cacialli, Anna Warren
Journal Of Materials Chemistry C, Jul 2013 DOI: 10.1039/c3tc31075b Journal Paper I24-Microfocus Macromolecular Crystallography open access Squeezing the most from every crystal: the fine details of data collection Tobias Krojer, Ashley C. W. Pike, Frank Von Delft
Acta Crystallographica Section D Biological Crystallography, 69 Jul 2013 DOI: 10.1107/S0907444913013280 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism Haohao Dong, Ping Li, Bettina Boettcher, Richard M. Elliott, Changjiang Dong
Rna, 19 (8) Jul 2013 DOI: 10.1261/rna.039057.113 Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Key mutations alter the cytochrome P450 BM3 conformational landscape and remove inherent substrate bias Christopher F. Butler, Caroline Peet, Amy E. Mason, Michael W. Voice, David Leys, Andrew W. Munro
Journal Of Biological Chemistry, 288 (35) Jul 2013 DOI: 10.1074/jbc.M113.479717 Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access Microcrystal manipulation with laser tweezers Armin Wagner, Ramona Duman, Bob Stevens, Andy Ward
Acta Crystallographica Section D Biological Crystallography, 69 Jul 2013 DOI: 10.1107/S090744491300958X Journal Paper I24-Microfocus Macromolecular Crystallography open access Autoindexing diffraction images with iMosflm Harold R. Powell, Owen Johnson, Andrew G. W. Leslie
Acta Crystallographica Section D Biological Crystallography, 69 (7) Jul 2013 DOI: 10.1107/S0907444912048524 Journal Paper I24-Microfocus Macromolecular Crystallography open access Investigation of DNA sequence recognition by a streptomycete MarR family transcriptional regulator through surface plasmon resonance and X-ray crystallography Clare E. M. Stevenson, Aoun Assaad, Govind Chandra, Tung B. K. Le, Sandra J. Greive, Mervyn J. Bibb, David Lawson
Nucleic Acids Research, June 2013 DOI: 10.1093/nar/gkt523 Journal Paper I24-Microfocus Macromolecular Crystallography open access Fragment-based screening maps inhibitor interactions in the ATP-binding site of checkpoint kinase 2 Cris Silva-Santisteban, Isaac Westwood, Kathy Boxall, Nathan Brown, Sam Peacock, Craig Mcandrews, Elaine Barrie, Meirion Richards, Amin Mirza, Antony W. Oliver, Rosemary Burke, Swen Hoelder, Keith Jones, G. Wynne Aherne, Julian Blagg, Ian Collins, Michelle D. Garrett, Rob L. M. Van Montfort
Plos One, 8 (6) June 2013 DOI: 10.1371/journal.pone.0065689 Journal Paper I02-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Class I HDAc's share a common mechanism of regulation by inositol phosphate Christopher Millard, Peter Watson, Ivana Celardo, Yuliya Gordiyenko, Shaun Cowley, Carol Robinson, Louise Fairall, John W. R. Schwabe
Molecular Cell, June 2013 DOI: 10.1016/j.molcel.2013.05.020 Journal Paper I24-Microfocus Macromolecular Crystallography open access Picornavirus uncoating intermediate captured in atomic detail Jingshan Ren, Xiangxi Wang, Zhongyu Hu, Qiang Gao, Yao Sun, Xuemei Li, Claudine Porta, Thomas Walter, Robert Gilbert, Yuguang Zhao, Danny Axford, Mark Williams, Katherine Mcauley, David J. Rowlands, Weidong Yin, Junzhi Wang, David I. Stuart, Zihe Rao, Elizabeth E. Fry
Nature Communications, 4 June 2013 DOI: 10.1038/ncomms2889 Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Structure of class B GPCR corticotropin-releasing factor receptor 1 Kaspar Hollenstein, James Kean, Andrea Bortolato, Robert K. Y. Cheng, Andrew S. Dore, Ali Jazayeri, Robert M. Cooke, Malcolm Weir, Fiona Marshall
Nature, 499 (7459) June 2013 DOI: 10.1038/nature12357 Structurally encoded intraclass differences in EphA clusters drive distinct cell responses Elena Seiradake, Andreas Schaupp, Daniel Del Toro Ruiz, Rainer Kaufmann, Nikolaos Mitakidis, Karl Harlos, A. Radu Aricescu, Rüdiger Klein, E. Yvonne Jones
Nature Structural & Molecular Biology, 20 (8) June 2013 DOI: 10.1038/nsmb.2617 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing Judith Reeks, Richard d. Sokolowski, Shirley Graham, Huanting Liu, James H. Naismith, Malcolm White
Biochemical Journal, 452 June 2013 DOI: 10.1042/BJ20130269 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry Manuel Hilbert, Michele C. Erat, Virginie Hachet, Paul Guichard, I. D. Blank, Isabelle Fluckiger, Leanne Slater, Edward D. Lowe, Georgios N. Hatzopoulos, Michel O. Steinmetz, Pierre Gonczy, Ioannis Vakonakis
Proceedings Of The National Academy Of Sciences, June 2013 DOI: 10.1073/pnas.1302721110 Journal Paper I02-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access X-ray crystal structure of ERK5 (MAPK7) in complex with a specific inhibitor Jonathan M. Elkins, Jing Wang, Xianming Deng, Michael J. Pattison, J. Simon C. Arthur, Tatiana Erazo, Nestor Gomez, Jose M. Lizcano, Nathanael S. Gray, Stefan Knapp
Journal Of Medicinal Chemistry, 56 (11) June 2013 DOI: 10.1021/jm4000837 Journal Paper I24-Microfocus Macromolecular Crystallography open access Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF N. G. Housden, J. T. S. Hopper, N. Lukoyanova, D. Rodriguez-Larrea, J. A. Wojdyla, A. Klein, R. Kaminska, H. Bayley, H. R. Saibil, C. V. Robinson, C. Kleanthous
Science, 340 (6140) June 2013 DOI: 10.1126/science.1237864 Molecular architecture of the ankyrin SOCS box family of Cul5-dependent E3 ubiquitin ligases Joao Muniz, Kunde Guo, Nadia J. Kershaw, Vikram Ayinampudi, Frank Von Delft, Jeffrey J. Babon, Alex Bullock
Journal Of Molecular Biology, June 2013 DOI: 10.1016/j.jmb.2013.06.015 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Structure of rhomboid protease in complex with β-lactam inhibitors defines the S2' cavity Kutti R. Vinothkumar, Olivier a. Pierrat, Jonathan m. Large, Matthew Freeman
Structure, May 2013 DOI: 10.1016/j.str.2013.03.013 Journal Paper I02-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Crystal structure of the integral membrane diacylglycerol kinase Dianfan Li, Joseph A. Lyons, Valerie Pye, Lutz Vogeley, David Aragao, Colin P. Kenyon, Syed T. A. Shah, Christine Doherty, Margaret Aherne, Martin Caffrey
Nature, 497 (7450) May 2013 DOI: 10.1038/nature12179 Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states Chitra A. Shintre, Ashley C. W. Pike, Quihong Li, Jung-In Kim, Alistair J. Barr, Solenne Goubin, Leela Shrestha, Jingjie Yang, Georgina Berridge, Jonathan Ross, Phillip J. Stansfeld, Mark S. P. Sansom, Aled M. Edwards, Chas Bountra, Brian D. Marsden, Frank Von Delft, Alex N. Bullock, Opher Gileadi, Nicola A. Burgess-Brown, Elisabeth P. Carpenter
Proceedings Of The National Academy Of Sciences, May 2013 DOI: 10.1073/pnas.1217042110 Journal Paper I24-Microfocus Macromolecular Crystallography open access Structural basis for Rab1 de-AMPylation by the Legionella pneumophila effector SidD Yang Chen, Igor Tascón, M. Ramona Neunuebel, Chiara Pallara, Jacqueline Brady, Lisa N. Kinch, Juan Fernández-Recio, Adriana Rojas, Matthias P. Machner, Aitor Hierro
Plos Pathogens, 9 (5) May 2013 DOI: 10.1371/journal.ppat.1003382 Journal Paper I24-Microfocus Macromolecular Crystallography open access ‘In crystallo’ substrate binding triggers major domain movements and reveals magnesium as a co-activator of Trypanosoma brucei pyruvate kinase Wenhe Zhong, Hugh P. Morgan, Iain W. Mcnae, Paul A.m. Michels, Linda A. Fothergill-Gilmore, Malcolm Walkinshaw
Acta Crystallographica Section D Biological Crystallography, 69 May 2013 DOI: 10.1107/S0907444913013875 Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Bacteriophage P23-77 capsid protein structures reveal the archetype of an ancient branch from a major virus lineage Ilona Rissanen, Jonathan M. Grimes, Alice Pawlowski, Sari Mäntynen, Karl Harlos, Jaana k. H. Bamford, David I. Stuart
Structure, Apr 2013 DOI: 10.1016/j.str.2013.02.026 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Marine Rhodobacteraceae l-haloacid dehalogenase contains a novel His/Glu dyad that could activate the catalytic water Leeni Novak, Chris Sayer, Misha Isupov, Konrad Paszkiewicz, Dorothee Gotz, Andrew Mearns Spragg, Jennifer Littlechild
Febs Journal, 280 (7) Apr 2013 DOI: 10.1111/febs.12177 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Investigating the active centre of the S. thermophilum catalase Yonca Yuzugullu, Chi Hung Trinh, Lucy Fairhurst, Zumrut B. Ogel, Michael J. Mcpherson, Arwen R. Pearson
Acta Crystallographica Section F Structural Biology And Crystallization Communications, 69 Apr 2013 DOI: 10.1107/S1744309113004211 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography Host lipid and temperature as important screening variables for crystallizing integral membrane proteins in lipidic mesophases. Trials with diacylglycerol kinase Dianfan Li, Syed T. A. Shah, Martin Caffrey
Crystal Growth & Design, 13 (7) Apr 2013 DOI: 10.1021/cg400254v Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization Antonio Ariza, Sian Tanner, Cheryl T. Walter, Kyle C. Dent, Dale A. Shepherd, Weining Wu, Susan V. Matthews, Julian A. Hiscox, Todd J. Green, Ming Luo, Richard M. Elliott, Anthony R. Fooks, Alison E. Ashcroft, Nicola J. Stonehouse, Neil A. Ranson, John N. Barr, Thomas A. Edwards
Nucleic Acids Research, Apr 2013 DOI: 10.1093/nar/gkt268 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access 14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins Philippe Riou, Svend Kjær, Ritu Garg, Andy Purkiss, Roger George, Robert J. Cain, Ganka Bineva, Nicolas Reymond, Brad Mccoll, Andrew Thompson, Nicola O'Reilly, Neil Mcdonald, Peter J. Parker, Anne J. Ridley
Cell, 153 (3) Apr 2013 DOI: 10.1016/j.cell.2013.03.044 Journal Paper I24-Microfocus Macromolecular Crystallography open access Structures of protein-protein complexes involved in electron transfer Svetlana V. Antonyuk, Cong Han, Robert R. Eady, S. Samar Hasnain
Nature, 496 (7443) Apr 2013 DOI: 10.1038/nature11996 Journal Paper I02-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Structural basis for kinesin-1:cargo recognition Stefano Pernigo, Anneri Lamprecht, Roberto A. Steiner, Mark P. Dodding
Science, 340 (6130) Apr 2013 DOI: 10.1126/science.1234264 Structure of the archaeal Cascade subunit Csa5: Relating the small subunits of CRISPR effector complexes Judith Reeks, Shirley Graham, Linzi Anderson, Huanting Liu, Malcolm F. White, James H. Naismith
Rna Biology, 10 (5) Apr 2013 DOI: 10.4161/rna.23854 Journal Paper I24-Microfocus Macromolecular Crystallography open access Biophysical fragment screening of the β1-adrenergic receptor: identification of high affinity arylpiperazine leads using structure-based drug design John Christopher, Jason Brown, Andrew Dore, James Errey, Markus Koglin, Fiona H. Marshall, Dave Myszka, Rebecca L. Rich, Christopher G. Tate, Benjamin Tehan, Tony Warne, Miles Congreve
Journal Of Medicinal Chemistry, 56 (9) Mar 2013 DOI: 10.1021/jm400140q Journal Paper I24-Microfocus Macromolecular Crystallography open access The structural basis of ZMPSTE24-dependent laminopathies A. Quigley, Y. Y. Dong, A. C. W. Pike, L. Dong, L. Shrestha, G. Berridge, P. J. Stansfeld, M. S. P. Sansom, A. M. Edwards, C. Bountra, F. Von Delft, A. N. Bullock, N. A. Burgess-Brown, E. P. Carpenter
Science, 339 (6127) Mar 2013 DOI: 10.1126/science.1231513 Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen Claudine Porta, Abhay Kotecha, Alison Burman, Terry Jackson, Jingshan Ren, Silvia Loureiro, Ian M. Jones, Elizabeth E. Fry, David I. Stuart, Bryan Charleston
Plos Pathogens, 9 (3) Mar 2013 DOI: 10.1371/journal.ppat.1003255 Journal Paper I24-Microfocus Macromolecular Crystallography open access Interactions of a periplasmic binding protein with a tetradentate siderophore mimic Daniel J. Raines, Olga V. Moroz, Keith S. Wilson, Anne-K. Duhme-Klair
Angewandte Chemie International Edition, Mar 2013 DOI: 10.1002/anie.201300751 Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Structure of Schmallenberg orthobunyavirus nucleoprotein suggests a novel mechanism for genome encapsidation Haohao Dong, Ping Li, Richard M. Elliott, Changjiang Dong
Journal Of Virology, Mar 2013 DOI: 10.1128/JVI.00223-13 Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Structure of the tubulin/FtsZ-like protein TubZ from Pseudomonas bacteriophage ΦKZ Christopher Aylett, Thierry Izore, Linda Amos, Jan Lowe
Journal Of Molecular Biology, 425 (12) Mar 2013 DOI: 10.1016/j.jmb.2013.03.019 Journal Paper I24-Microfocus Macromolecular Crystallography open access RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover B. T. Goult, T. Zacharchenko, N. Bate, R. Tsang, F. Hey, A. R. Gingras, P. Elliott, G. C. K. Roberts, C. Ballestrem, D. R. Critchley, I. L. Barsukov
Journal Of Biological Chemistry, 288 (12) Mar 2013 DOI: 10.1074/jbc.M112.438119 Journal Paper I24-Microfocus Macromolecular Crystallography open access Structure determination from a single high-pressure-frozen virus crystal Anja Burkhardt, Armin Wagner, Martin Warmer, Rudolph Reimer, Heinrich Hohenberg, Jingshan Ren, Elizabeth E. Fry, David I. Stuart, Alke Meents
Acta Crystallographica Section D Biological Crystallography, 69 Feb 2013 DOI: 10.1107/S090744491204543X Structural insights into the regulation of cohesion establishment by Wpl1 Avradip Chatterjee, Silva Zakian, Xiao-Wen Hu, Martin R. Singleton
The Embo Journal, Feb 2013 DOI: 10.1038/emboj.2013.16 Journal Paper I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access The structure of F1-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF1 Graham C. Robinson, John Bason, Martin Montgomery, Ian M. Fearnley, David M. Mueller, Andrew G. W. Leslie, John E. Walker
Open Biology, 3 Feb 2013 DOI: 10.1098/rsob.120164 Journal Paper I24-Microfocus Macromolecular Crystallography open access Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis Muhammad Saleem, Stephen M. Prince, Stephen E. J. Rigby, Muhammad Imran, Hema Patel, Hannah Chan, Holly Sanders, Martin C. J. Maiden, Ian M. Feavers, Jeremy P. Derrick
Plos One, 8 (2) Feb 2013 DOI: 10.1371/journal.pone.0056746 Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Structural integrity of the B24 site in human insulin is important for hormone functionality Lenka Zakova, Emília Kletvíková, Vaclav Veverka, Martin Lepsik, Christopher J. Watson, Johan P. Turkenburg, Jiri Jiracek, Andrzej M. Brzozowski
Journal Of Biological Chemistry, Feb 2013 DOI: 10.1074/jbc.M112.448050 Journal Paper I24-Microfocus Macromolecular Crystallography open access Activity-based probes for rhomboid proteases discovered in a mass spectrometry-based assay Oliver Vosyka, Kutti R. Vinothkumar, Eliane V. Wolf, Arwin J. Brouwer, Rob M. J. Liskamp, Steven H. L. Verhelst
Proceedings Of The National Academy Of Sciences, 110 (7) Feb 2013 DOI: 10.1073/pnas.1215076110 Journal Paper I02-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography How insulin engages its primary binding site on the insulin receptor John Menting, Jonathan Whittaker, Mai B. Margetts, Linda J. Whittaker, Geoffrey K.-W. Kong, Brian J. Smith, Christopher J. Watson, Lenka Záková, Emília Kletvíková, Jiří Jiráček, Shu Jin Chan, Donald F. Steiner, Guy G. Dodson, Andrzej M. Brzozowski, Michael A. Weiss, Colin W. Ward, Michael C. Lawrence
Nature, 493 Jan 2013 DOI: 10.1038/nature11781 Structural basis for Cul3 assembly with the BTB-Kelch family of E3 ubiquitin ligases Peter Canning, Christopher D. O. Cooper, Tobias Krojer, James W. Murray, Ashley C. W. Pike, Apirat Chaikuad, Tracy Keates, Chancievan Thangaratnarajah, Viktorija Hojzan, Brian D. Marsden, Opher Gileadi, Stefan Knapp, Frank Von Delft, Alex N. Bullock
Journal Of Biological Chemistry, Jan 2013 DOI: 10.1074/jbc.M112.437996 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access To scavenge or not to scavenge, that is STILL the question Elizabeth G. Allan, Ian Carmichael, Elspeth F. Garman, Melissa C. Kander
Journal Of Synchrotron Radiation, 20 Jan 2013 DOI: 10.1107/S0909049512046237 Journal Paper I02-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Expression, purification and crystallization of the ectodomain of the envelope glycoprotein E2 from Bovine viral diarrhoea virus Oleg Iourin, Karl Harlos, Kamel El Omari, Weixian Lu, Jan Kadlec, Munir Iqbal, Christoph Meier, Andrew Palmer, Ian Jones, Carole Thomas, Joe Brownlie, Jonathan M. Grimes, David I. Stuart
Acta Crystallographica Section F Structural Biology And Crystallization Communications, 69 Jan 2013 DOI: 10.1107/S1744309112049184 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography