Instruments by Science Group
Macromolecular
Soft Condensed 
Imaging and
Biological
Magnetic
Structures and
Crystallography 
Spectroscopy I03 Contact
Beamline Phone Number:
+44 (0) 1235 778707
Acting Principal Beamline Scientist:
Dave Hall
Tel: +44 (0) 1235 778926
E-mail: [email protected]
Science Group Leader
Dave Hall
Email: [email protected]
Tel: +44 (0) 1235 778926
I03 MX
Status: Operational
Beamsize: 90 µm x 20 µm
Detector: Eiger2 XE 16M
Wavelength: 0.50 - 2.07 Å
Energy: 6 - 25 keV
Detector: Eiger2 XE 16M
Wavelength: 0.50 - 2.07 Å
Energy: 6 - 25 keV
These publications are based on data gathered on beamline I03. If you are aware of any errors or publications that should be listed here, please send details to [email protected].
66 items found for 2010 [total: 2353]
Cloning, purification and preliminary crystallographic analysis of cobalamin methyltransferases from Rhodobacter capsulatus Acta Crystallographica Section F Structural Biology And Crystallization Communications, 66 (12) Dec 2010 DOI: 10.1107/S1744309110042910
TOPSORT: TCR optimized peptide skewing of the repertoire of T-cells Dec 2010
Conference Paper I03-Macromolecular Crystallography
The crystal structure of the ubiquitin-like (UbL) domain of human homologue A of Rad23 (hHR23A) protein Protein Engineering Design And Selection, 24 Dec 2010 DOI: 10.1093/protein/gzq084
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Structural and mechanistic studies on γ-butyrobetaine hydroxylase Chemistry & Biology, 17 (12) Dec 2010 DOI: 10.1016/j.chembiol.2010.09.016
Using structural information to change the phosphotransfer specificity of a two-component chemotaxis signalling complex. Plos Biology, 8 (2) Dec 2010 DOI: 10.1371/journal.pbio.1000306
Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains Proceedings Of The National Academy Of Sciences, 108 (6) Dec 2010 DOI: 10.1073/pnas.1015287108
Journal Paper I03-Macromolecular Crystallography
Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis Acta Crystallographica Section F Structural Biology And Crystallization Communications, 66 (10) Dec 2010 DOI: 10.1107/S1744309110039679
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen Journal Of Biological Chemistry, 285 (49) Dec 2010 DOI: 10.1074/jbc.M110.164293
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Structural basis of semaphorin-plexin signalling. Nature, 467 Dec 2010 DOI: 10.1038/nature09468
Journal Paper I03-Macromolecular Crystallography
Structure of the nucleoprotein binding domain of Mokola virus phosphoprotein Journal Of Virology, 84 (2) Dec 2010 DOI: 10.1128/JVI.01520-09
Journal Paper I03-Macromolecular Crystallography
Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding Protein Science, 19 (12) Dec 2010 DOI: 10.1002/pro.507
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Structural basis of poly(ADP-ribose) recognition by the multizinc binding domain of checkpoint with forkhead-associated and RING domains (CHFR) Journal Of Biological Chemistry, 285 (50) Dec 2010 DOI: 10.1074/jbc.M110.159855
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr Virus infection Plos Pathogens, Nov 2010 DOI: 10.1371/journal.ppat.1001198
Crystallization and initial X-ray diffraction analysis of the tellurite-resistance S-adenosyl-L-methionine transferase protein TehB from Escherichia coli Acta Crystallographica Section F Structural Biology And Crystallization Communications, 66 (11) Nov 2010 DOI: 10.1107/S1744309110036043
Journal Paper I03-Macromolecular Crystallography
Cap binding and immune evasion revealed by Lassa nucleoprotein structure Nature, 468 Nov 2010 DOI: 10.1038/nature09605
Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex Journal Of Biological Chemistry, 286 (2) Nov 2010 DOI: 10.1074/jbc.M110.195842
Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization Journal Of Medicinal Chemistry, 53 (21) Nov 2010 DOI: 10.1021/jm1008727
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Structure and functional analysis of LptC, a conserved membrane protein involved in the lipopolysaccharide export pathway in Escherichia coli Journal Of Biological Chemistry, 285 (43) Oct 2010 DOI: 10.1074/jbc.M110.144709
Circular permutation provides an evolutionary link between two families of calcium-dependent carbohydrate binding modules Journal Of Biological Chemistry, 285 (41) Oct 2010 DOI: 10.1074/jbc.M110.142133
Characterization of a novel WDR5-binding Site that recruits RbBP5 through a conserved motif to enhance methylation of histone H3 lysine 4 by mixed lineage leukemia protein-1 Journal Of Biological Chemistry, 285 (43) Oct 2010 DOI: 10.1074/jbc.M110.159921
A redox switch in angiotensinogen modulates angiotensin release Nature, Oct 2010 DOI: 10.1038/nature09505
Structure and metal loading of a soluble periplasm cuproprotein Journal Of Biological Chemistry, 285 (42) Oct 2010 DOI: 10.1074/jbc.M110.153080
Structural insights into substrate specificity in variants of N-acetylneuraminic acid lyase produced by directed evolution Journal Of Molecular Biology, Sept 2010 DOI: 10.1016/j.jmb.2010.08.008
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
The structural basis for catalysis and substrate specificity of a rhomboid protease The Embo Journal, Sept 2010 DOI: 10.1038/emboj.2010.243
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Crystallization and preliminary X-ray analysis of a glucansucrase from the dental caries pathogen Streptococcus mutans Acta Crystallographica Section F Structural Biology And Crystallization Communications, 66 (9) Sept 2010 DOI: 10.1107/S1744309110029714
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation Journal Of Biological Chemistry, 285 (49) Sept 2010 DOI: 10.1074/jbc.M110.177717
The structure of the FnIII Tandem A77-A78 points to a periodically conserved architecture in the myosin-binding region of titin Journal Of Molecular Biology, 401 (5) Sept 2010 DOI: 10.1016/j.jmb.2010.06.011
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
The Scottish Structural Proteomics Facility: targets, methods and outputs Journal Of Structural And Functional Genomics, 11 Sept 2010 DOI: 10.1007/s10969-010-9090-y
A highly unusual thioester bond in a pilus adhesin is required for efficient host cell interaction. Journal Of Biological Chemistry, Aug 2010 DOI: 10.1074/jbc.M110.149385
Visualizing the metal-binding versatility of copper trafficking sites Biochemistry, 49 (36) Aug 2010 DOI: 10.1021/bi101064w
Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4. Journal Of Molecular Biology, 401 (3) Aug 2010 DOI: 10.1016/j.jmb.2010.06.017
Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-'A' from Rhodococcus ruber DSM 44541 Chemical Communications, 46 (34) Aug 2010 DOI: 10.1039/c0cc00929f
Journal Paper I03-Macromolecular Crystallography
Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity Journal Of Medicinal Chemistry, Aug 2010 DOI: 10.1021/jm100470t
Journal Paper I03-Macromolecular Crystallography
Structural studies of ligand recognition by the collectins hSP-D, CL-46 and conglutinin Jul 2010
Thesis I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor Journal Of Medicinal Chemistry, 53 (14) Jul 2010 DOI: 10.1021/jm100249w
Journal Paper I03-Macromolecular Crystallography
Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster Biochemical And Biophysical Research Communications, Jul 2010 DOI: 10.1016/j.bbrc.2010.06.113
Journal Paper I03-Macromolecular Crystallography
Structural basis for assembly of Hsp90-Sgt1-CHORD protein complexes: implications for chaperoning of NLR innate immunity receptors Molecular Cell, 39(2) Jul 2010 DOI: 10.1016/j.molcel.2010.05.010
Crystal structures of Bacillus subtilis Lon protease Journal Of Molecular Biology, 401 (4) June 2010 DOI: 10.1016/j.jmb.2010.06.030
X-ray crystal structure and time-resolved spectroscopy of the blue carotenoid violerythrin Journal Of Physical Chemistry B, 114 (26) June 2010 DOI: 10.1021/jp101296a
Journal Paper I03-Macromolecular Crystallography
Structural basis of gate-DNA breakage and resealing by Type II topoisomerases Plos One, 5 (6) June 2010 DOI: 10.1371/journal.pone.0011338
A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex Cell, June 2010 DOI: 10.1016/j.cell.2010.05.006
Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family Structure, 18 (6) June 2010 DOI: 10.1016/j.str.2010.03.008
Journal Paper I03-Macromolecular Crystallography
High-resolution crystal structures of Drosophila melanogaster angiotensin-converting enzyme in complex with novel inhibitors and antihypertensive drugs Journal Of Molecular Biology, 400 (3) May 2010 DOI: 10.1016/j.jmb.2010.05.024
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Mammal-restricted elements predispose human RET to folding impairment by HSCR mutations Nature Structural & Molecular Biology, 17 (6) May 2010 DOI: 10.1038/nsmb.1808
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography
The structure of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei reveals a zinc binding site at the heart of the active site Journal Of Molecular Biology, 400 (3) May 2010 DOI: 10.1016/j.jmb.2010.04.058
Crystallization and initial X-ray diffraction analysis of a mannose-binding lectin from champedak Acta Crystallographica Section F Structural Biology And Crystallization Communications, 66 (5) May 2010 DOI: 10.1107/S1744309110011760
Journal Paper I03-Macromolecular Crystallography
Crystal structure of human RNA helicase A (DHX9): Structural basis for unselective nucleotide base binding in a DEAD-box variant protein Journal Of Molecular Biology, 400 (4) May 2010 DOI: 10.1016/j.jmb.2010.05.046
Journal Paper I03-Macromolecular Crystallography
Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3 Biochemical Journal, 427 (3) Apr 2010 DOI: 10.1042/BJ20091603
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Domain cross-talk during effector binding to the multidrug binding TTGR regulator Journal Of Biological Chemistry, 285(28) Apr 2010 DOI: 10.1074/jbc.M110.113282
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Allosteric mechanism of pyruvate kinase from Leishmania mexicana uses a rock and lock model Journal Of Biological Chemistry, 285 (17) Apr 2010 DOI: 10.1074/jbc.M109.079905
Journal Paper I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Structural homology between the C-terminal domain of the PapC usher and its plug Journal Of Bacteriology, 192 (7) Apr 2010 DOI: 10.1128/JB.01677-09
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
With phases: how two wrongs can sometimes make a right Acta Crystallographica Section D Biological Crystallography, 66 (4) Apr 2010 DOI: 10.1107/S0907444909048112
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition Journal Of Biological Chemistry, 285 (19) Apr 2010 DOI: 10.1074/jbc.M109.082016
Chimeric microtubule disruptors Chemical Communications, 46 (17) Mar 2010 DOI: 10.1039/c002558e
Journal Paper I03-Macromolecular Crystallography
An analysis of substrate binding interactions in the heme peroxidase enzymes Archives Of Biochemistry And Biophysics, 500 (1) Mar 2010 DOI: 10.1016/j.abb.2010.02.015
Structural basis of substrate binding in WsaF, a rhamnosyltransferase from Geobacillus stearothermophilus Journal Of Molecular Biology, 397 (2) Mar 2010 DOI: 10.1016/j.jmb.2010.01.035
Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites Developmental & Comparative Immunology, 34 (2) Feb 2010 DOI: 10.1016/j.dci.2009.08.012
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex Proceedings Of The National Academy Of Sciences, 107 (7) Feb 2010 DOI: 10.1073/pnas.0913736107
Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches Journal Of Medicinal Chemistry, 53 (4) Jan 2010 DOI: 10.1021/jm901680b
Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes Biochemistry, 49 (8) Jan 2010 DOI: 10.1021/bi901970c
Journal Paper I03-Macromolecular Crystallography
Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme Chembiochem, 11 (2) Jan 2010 DOI: 10.1002/cbic.200900570
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78 Plos One, 5 (1) Jan 2010 DOI: 10.1371/journal.pone.0008625
Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein Proceedings Of The National Academy Of Sciences, 107 (5) Jan 2010 DOI: 10.1073/pnas.0910715107
ATP-dependent MurE ligase in Mycobacterium tuberculosis: Biochemical and structural characterisation Tuberculosis, 90 (1) Jan 2010 DOI: 10.1016/j.tube.2009.10.007
Journal Paper I03-Macromolecular Crystallography
Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2 Bioorganic & Medicinal Chemistry, 18 (2) Jan 2010 DOI: 10.1016/j.bmc.2009.11.058
Structural insights into the prereaction state of pyruvate decarboxylase from Zymomonas mobilis Biochemistry, 49 (8) Jan 2010 DOI: 10.1021/bi901864j
- Thomas Hutchison, Teng To, Evelyne Deery, Amanda Brindley, Martin J. Warren, Richard W. Pickersgill, Arefeh Seyedarabi, "Cloning, purification and preliminary crystallographic analysis of cobalamin methyltransferases from Rhodobacter capsulatus", Acta Crystallographica Section F Structural Biology And Crystallization Communications, 66 (12), 1652-1656 (2010), DOI: 10.1107/S1744309110042910
- [Conference Paper] J. Ekeruche, M. Clement, D. K. Cole, K. Ladell, E. Edwards, John Miles, K. Wynn, A. Fuller, A. Lissina, E. Gostick, "TOPSORT: TCR optimized peptide skewing of the repertoire of T-cells" (2010)
- Y. W. Chen, T. Tajima, S. Agrawal, "The crystal structure of the ubiquitin-like (UbL) domain of human homologue A of Rad23 (hHR23A) protein", Protein Engineering Design And Selection, 24, 131 - 138 (2010), DOI: 10.1093/protein/gzq084
- Ivanhoe K. H. Leung, Tobias J. Krojer, Grazyna T. Kochan, Luc Henry, Frank Von Delft, Timothy D. W. Claridge, Udo Oppermann, Michael A. Mcdonough, Christopher J. Schofield, "Structural and mechanistic studies on γ-butyrobetaine hydroxylase", Chemistry & Biology, 17 (12), 1316 - 1324 (2010), DOI: 10.1016/j.chembiol.2010.09.016
- Christian H Bell, Steven L Porter, Annabel Strawson, David I. Stuart, Judith P. Armitage, "Using structural information to change the phosphotransfer specificity of a two-component chemotaxis signalling complex.", Plos Biology, 8 (2) (2010), DOI: 10.1371/journal.pbio.1000306
- M. Akutsu, Y. Ye, S. Virdee, J. W. Chin, D. Komander, "Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains", Proceedings Of The National Academy Of Sciences, 108 (6), 2228 - 2233 (2010), DOI: 10.1073/pnas.1015287108
- Mads Gabrielsen, Caroline E. Zetterström, Dai Wang, Katherine Beckham, Mikael Elofsson, Neil W. Isaacs, Andrew J. Roe, "Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis", Acta Crystallographica Section F Structural Biology And Crystallization Communications, 66 (10), 1606-1609 (2010), DOI: 10.1107/S1744309110039679
- Max D. Driscoll, Kirsty J. Mclean, Colin Levy, Nathalia Mast, Irina A Pikuleva, David Leys, Pierre Lafite, Stephen E. J. Rigby, Andrew W. Munro, "Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen", Journal Of Biological Chemistry, 285 (49), 38270-82 (2010), DOI: 10.1074/jbc.M110.164293
- Bert J. C. Janssen, Ross A. Robinson, Francesc Perez-Branguli, Christian H Bell, Kevin J Mitchell, Christian Siebold, E. Yvonne Jones, "Structural basis of semaphorin-plexin signalling.", Nature, 467, 1118-1122 (2010), DOI: 10.1038/nature09468
- René Assenberg, Olivier Delmas, Jingshan Ren, Pierre-Olivier Vidalain, Anil Verma, Florence Larrous, Stephen C. Graham, Frédéric Tangy, Jonathan M. Grimes, Hervé Bourhy, "Structure of the nucleoprotein binding domain of Mokola virus phosphoprotein", Journal Of Virology, 84 (2), 1089-1096 (2010), DOI: 10.1128/JVI.01520-09
- Joel L. Kaar, Nicolas Basse, Andreas C. Joerger, Elaine Stephens, Trevor J. Rutherford, Alan R. Fersht, "Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding", Protein Science, 19 (12), 2267-2278 (2010), DOI: 10.1002/pro.507
- J. Oberoi, M. W. Richards, S. Crumpler, N. Brown, J. Blagg, R. Bayliss, "Structural basis of poly(ADP-ribose) recognition by the multizinc binding domain of checkpoint with forkhead-associated and RING domains (CHFR)", Journal Of Biological Chemistry, 285 (50), 39348 - 39358 (2010), DOI: 10.1074/jbc.M110.159855
- John J. Miles, Anna M. Bulek, David K. Cole, Emma Gostick, Andrea J. Schauenburg, Garry Dolton, Vanessa Venturi, Miles Daveport, Mai Ping Tan, Scott Burrows, Linda Woolridge, David A. Price, Pierre J. Rizkallah, Andrew K. Sewell, "Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr Virus infection", Plos Pathogens (2010), DOI: 10.1371/journal.ppat.1001198
- Hassan Choudhury, Konstantinos Beis, "Crystallization and initial X-ray diffraction analysis of the tellurite-resistance S-adenosyl-L-methionine transferase protein TehB from Escherichia coli", Acta Crystallographica Section F Structural Biology And Crystallization Communications, 66 (11), 1496-1499 (2010), DOI: 10.1107/S1744309110036043
- Xiaoxuan Qi, Shuiyun Lan, Wenjian Wang, Lisa Mclay Schelde, Haohao Dong, Gregor D. Wallat, Hinh Ly, Yuying Liang, Changjiang Dong, "Cap binding and immune evasion revealed by Lassa nucleoprotein structure", Nature, 468, 779 - 783 (2010), DOI: 10.1038/nature09605
- Sara Lejon , Sock Yue Thong, Andal Murthy, Saad Alqarni, Nathalie V. Murzina, Gerd A. Blobel, Ernest D. Laue, Joel P. Mackay, "Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex", Journal Of Biological Chemistry, 286 (2), 1196-1203 (2010), DOI: 10.1074/jbc.M110.195842
- Daniel K. Whelligan, Savade Solanki, Dawn Taylor, Douglas W. Thomson, Kwai-Ming J. Cheung, Kathy Boxall, Corine Mas-Droux, Caterina Barillari, Samantha Burns, Charles G. Grummitt, Ian Collins, Rob L. M. Van Montfort, G. Wynne Aherne, Richard Bayliss, Swen Hoelder, "Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization", Journal Of Medicinal Chemistry, 53 (21), 7682 - 7698 (2010), DOI: 10.1021/jm1008727
- A. X. Tran, C. Dong, C. Whitfield, "Structure and functional analysis of LptC, a conserved membrane protein involved in the lipopolysaccharide export pathway in Escherichia coli", Journal Of Biological Chemistry, 285 (43), 33529 - 33539 (2010), DOI: 10.1074/jbc.M110.144709
- Cedric Montanier, James E. Flint, David N. Bolam, Hefang Xie, Ziyang Liu, Artur Rogowski, David P. Weiner, Supriya Ratnaparkhe, Didier Nurizzo, Shirley Roberts, Johan Turkenburg, Gideon J. Davies, Harry J. Gilbert, "Circular permutation provides an evolutionary link between two families of calcium-dependent carbohydrate binding modules", Journal Of Biological Chemistry, 285 (41), 31742 - 31754 (2010), DOI: 10.1074/jbc.M110.142133
- Zain Odho, Stacey M. Southall, Jon R. Wilson, "Characterization of a novel WDR5-binding Site that recruits RbBP5 through a conserved motif to enhance methylation of histone H3 lysine 4 by mixed lineage leukemia protein-1", Journal Of Biological Chemistry, 285 (43), 32967-32976 (2010), DOI: 10.1074/jbc.M110.159921
- Aiwu Zhou, Robin W. Carrell, Michael P. Murphy, Zhenquan Wei, Yahui Yan, Peter L. D. Stanley, Penelope E. Stein, Fiona Broughton Pipkin, Randy J. Read, "A redox switch in angiotensinogen modulates angiotensin release", Nature (2010), DOI: 10.1038/nature09505
- K. J. Waldron, Susan Firbank, S. J. Dainty, M. Perez-Rama, S. Tottey, N. J. Robinson, "Structure and metal loading of a soluble periplasm cuproprotein", Journal Of Biological Chemistry, 285 (42), 32504 - 32511 (2010), DOI: 10.1074/jbc.M110.153080
- Ivan Campeotto, Amanda H. Bolt, Thomas Harman , Caitriona Dennis, Chi Hung Trinh, Simon Phillips, Adam Nelson, Alan Berry, Arwen Pearson, "Structural insights into substrate specificity in variants of N-acetylneuraminic acid lyase produced by directed evolution", Journal Of Molecular Biology (2010), DOI: 10.1016/j.jmb.2010.08.008
- Kutti R. Vinothkumar, Kvido Strisovsky, Antonina Andreeva, Yonka Christova, Steven Verhelst, Matthew Freeman, "The structural basis for catalysis and substrate specificity of a rhomboid protease", The Embo Journal (2010), DOI: 10.1038/emboj.2010.243
- Keisuke Ito , Sohei Ito, Tatsuro Shimamura, Yasuaki Kawarasaki, Keiko Abe, Takumi Misaka, Takuya Kobayashi, So Iwata, "Crystallization and preliminary X-ray analysis of a glucansucrase from the dental caries pathogen Streptococcus mutans", Acta Crystallographica Section F Structural Biology And Crystallization Communications, 66 (9), 1086-1088 (2010), DOI: 10.1107/S1744309110029714
- D. Sean Froese, Grazyna Kochan, João R. C. Muniz, Xuchu Wu, Carina Gileadi, Emelie Ugochukwu, Ewelina Krysztofinska, Roy A. Gravel, Udo Oppermann, Wyatt W. Yue, "Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation", Journal Of Biological Chemistry, 285 (49), 38204-38213 (2010), DOI: 10.1074/jbc.M110.177717
- Olga Mayans, Rainer M. Bucher, Dmitri I. Svergun, Claudia Muhle-Goll, "The structure of the FnIII Tandem A77-A78 points to a periodically conserved architecture in the myosin-binding region of titin", Journal Of Molecular Biology, 401 (5), 843-53 (2010), DOI: 10.1016/j.jmb.2010.06.011
- Muse Oke, Lester G. Carter, Kenneth A. Johnson, Huanting Liu, Stephen A. Mcmahon, Xuan Yan, Melina Kerou, Nadine D. Weikart, Nadia Kadi, Md. Arif Sheikh, Stefan Schmelz, Mark Dorward, Michal Zawadzki, Christopher Cozens, Helen Falconer, Helen Powers, Ian M. Overton, C. A. Johannes Van Niekerk, Xu Peng, James H. Naismith, "The Scottish Structural Proteomics Facility: targets, methods and outputs", Journal Of Structural And Functional Genomics, 11, 167 - 180 (2010), DOI: 10.1007/s10969-010-9090-y
- Jonathan Pointon, Wendy Smith, Gerhard Saalbach, Allister Crow, Michael A. Kehoe, Mark J. Banfield, "A highly unusual thioester bond in a pilus adhesin is required for efficient host cell interaction.", Journal Of Biological Chemistry (2010), DOI: 10.1074/jbc.M110.149385
- Adriana Badarau, Susan J. Firbank, Andrew A. Mccarthy, Mark J. Banfield, Christopher Dennison, "Visualizing the metal-binding versatility of copper trafficking sites", Biochemistry, 49 (36), 77987810 (2010), DOI: 10.1021/bi101064w
- Panagis Filippakopoulos, Andrew Low, Timothy D. Sharpe, Jonas Uppenberg, Shenggen Yao, Zhihe Kuang, Pavel Savitsky, Rowena S. Lewis, Sandra E. Nicholson, Raymond S. Norton, Alex N. Bullock, "Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.", Journal Of Molecular Biology, 401 (3), 389 (2010), DOI: 10.1016/j.jmb.2010.06.017
- Martin Karabec, Andrzej Łyskowski, Katharina C. Tauber, Georg Steinkellner, Wolfgang Kroutil, Gideon Grogan, Karl Gruber, "Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-'A' from Rhodococcus ruber DSM 44541", Chemical Communications, 46 (34), 6314-6316 (2010), DOI: 10.1039/c0cc00929f
- Erik Chorell, Jerome S. Pinkner, Gilles Phan , Sofie Edvinson, Floris Buelens, Han Remaut, Gabriel Waksman, Scott J. Hultgren, Fredrik Almqvist, "Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity", Journal Of Medicinal Chemistry (2010), DOI: 10.1021/jm100470t
- [Thesis] Amy Shaw, "Structural studies of ligand recognition by the collectins hSP-D, CL-46 and conglutinin" (2010)
- Tobias Karlberg, Natalia Markova, Ida Johansson, Martin Hammarstrom, Patrick Schutz, Johan Weigelt, Herwig Schuler, "Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor", Journal Of Medicinal Chemistry, 53 (14), 53552-5355 (2010), DOI: 10.1021/jm100249w
- Akif Mohd, Ioanna Ntai, Edward Sturrock, R Elwyn Isaac, Brian Bachmann, Ravi Acharya, "Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster", Biochemical And Biophysical Research Communications (2010), DOI: 10.1016/j.bbrc.2010.06.113
- Minghao Zhang, Yasuhiro Kadota, Chrisostomos Prodromou, Ken Shirasu, Laurence H. Pearl, "Structural basis for assembly of Hsp90-Sgt1-CHORD protein complexes: implications for chaperoning of NLR innate immunity receptors", Molecular Cell, 39(2), 269-281 (2010), DOI: 10.1016/j.molcel.2010.05.010
- Ramona Duman, Jan Lowe, "Crystal structures of Bacillus subtilis Lon protease", Journal Of Molecular Biology, 401 (4), 653-670 (2010), DOI: 10.1016/j.jmb.2010.06.030
- Tomas Polivka, Harry A. Frank, Miriam M. Enriquez, Dariusz M. Niedzwiedzki, Synnove Liaaen-Jenson, Joanna Hemming, Madeleine Helliwell, John R. Helliwell, "X-ray crystal structure and time-resolved spectroscopy of the blue carotenoid violerythrin", Journal Of Physical Chemistry B, 114 (26), 8760-8769 (2010), DOI: 10.1021/jp101296a
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