Instruments by Science Group
Macromolecular
Soft Condensed 
Imaging and
Biological
Magnetic
Structures and
Crystallography 
Spectroscopy I03 Contact
Beamline Phone Number:
+44 (0) 1235 778707
Acting Principal Beamline Scientist:
Dave Hall
Tel: +44 (0) 1235 778926
E-mail: [email protected]
Science Group Leader
Dave Hall
Email: [email protected]
Tel: +44 (0) 1235 778926
I03 MX
Status: Operational
Beamsize: 90 µm x 20 µm
Detector: Eiger2 XE 16M
Wavelength: 0.50 - 2.07 Å
Energy: 6 - 25 keV
Detector: Eiger2 XE 16M
Wavelength: 0.50 - 2.07 Å
Energy: 6 - 25 keV
These publications are based on data gathered on beamline I03. If you are aware of any errors or publications that should be listed here, please send details to [email protected].
19 items found for 2008 [total: 2353]
Exploring the mechanism of tryptophan 2,3-dioxygenase Biochemical Society Transactions, 36 Dec 2008 DOI: 10.1042/BST0361120
A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex Nature, Nov 2008 DOI: 10.1038/nature07422
Journal Paper I03-Macromolecular Crystallography
Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL The Embo Journal, 27 (23) Nov 2008 DOI: 10.1038/emboj.2008.235
Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans. Acta Crystallographica Section F Structural Biology And Crystallization Communications, 64(12) Nov 2008 DOI: 10.1107/S1744309108037056
Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proceedings Of The National Academy Of Sciences, 105 Nov 2008 DOI: 10.1073/pnas.0807142105
Journal Paper I03-Macromolecular Crystallography
Molecular architecture of the "stressosome," a signal integration and transduction hub Science, 322 (5898) Oct 2008 DOI: 10.1126/science.1159572
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines Nature Structural & Molecular Biology, 15 (10) Oct 2008 DOI: 10.1038/nsmb.1484
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Structural insights into mechanism and specificity of O-GlcNAc transferase The Embo Journal, 27 (20) Sept 2008 DOI: 10.1038/emboj.2008.186
Vaccinia virus proteins A52 and B14 share a Bcl-2–like fold but have evolved to inhibit NF-κB rather than apoptosis Plos Pathogens, 4 (8) Aug 2008 DOI: 10.1371/journal.ppat.1000128
Macromolecular crystallography at Diamond Light Source: Automation and pathogenic sample environment Acta Crystallographica Section A, 64 Aug 2008 DOI: 10.1107/S0108767308094440
Poster I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Structural and functional analysis of the Crb2–BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair Genes And Development, 22 (15) Aug 2008 DOI: 10.1101/gad.472808
Journal Paper I03-Macromolecular Crystallography
Experience from operation and commissioning of the Phase 1 MX beamlines at Diamond Light Source Aug 2008
Conference Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125 Journal Of Biological Chemistry, 283 (31) Aug 2008 DOI: 10.1074/jbc.M803026200
The FACT Spt16 'peptidase' domain is a histone H3'H4 binding module Proceedings Of The National Academy Of Sciences, 105 (26) June 2008 DOI: 10.1073/pnas.0712293105
Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Structure of the DNA repair helicase XPD Cell, 133 (5) May 2008 DOI: 10.1016/j.cell.2008.04.029
Journal Paper I03-Macromolecular Crystallography
Decoding of methylated histone H3 tail by the pygo-BCL9 Wnt signaling complex Molecular Cell, 30 (4) May 2008 DOI: 10.1016/j.molcel.2008.03.011
Structures of the Shigella flexneriType 3 secretion system protein MxiC reveal conformational variability amongst homologues Journal Of Molecular Biology, 377 (4) Apr 2008 DOI: 10.1016/j.jmb.2008.01.072
Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex Proceedings Of The National Academy Of Sciences, 105 (12) Mar 2008 DOI: 10.1073/pnas.0711055105
Journal Paper I03-Macromolecular Crystallography
Structure of the topoisomerase IV from S. pneumoniae with a DNA target and quinolone drug Acta Crystallographica Section A Foundations of Crystallography, 64 Jan 2008
Poster I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-Macromolecular Crystallography
- Sarah J. Thackray, Christopher G. Mowat, Stephen K. Chapman, "Exploring the mechanism of tryptophan 2,3-dioxygenase", Biochemical Society Transactions, 36, 1120-1123 (2008), DOI: 10.1042/BST0361120
- Bernie Kelly, Airlie Mccoy, Kira Spate, Sharon Miller, Stefan Honing, David Owen, Phil Evans, "A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex", Nature (2008), DOI: 10.1038/nature07422
- Stephane Mouilleron, Sebastian Guettler, Carola Langer, Richard Treisman, Neil Mcdonald, "Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL", The Embo Journal, 27 (23), 3198 - 3208 (2008), DOI: 10.1038/emboj.2008.235
- Chi H. Trinh, Thérèse Hunter, Emma E. Stewart, Simon E. V. Phillips, Gary J. Hunter, "Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans.", Acta Crystallographica Section F Structural Biology And Crystallization Communications, 64(12), 1110-1114 (2008), DOI: 10.1107/S1744309108037056
- Rupert J. Russell, Philip S. Kerry, David J. Stevens, David A. Steinhauer, Stephen Martin, Steven J. Gamblin, John J. Skehel, "Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion", Proceedings Of The National Academy Of Sciences, 105, 17736-17741 (2008), DOI: 10.1073/pnas.0807142105
- Jon Marles-Wright, Tim Grant, Olivier Delumeau, Gijs Van Duinen, Susan J. Firbank, Peter J. Lewis, James W. Murray, Joseph A. Newman, Maureen B. Quin, Paul R. Race, Alexis Rohou, Marin Van Heel, Richard J. Lewis, "Molecular architecture of the "stressosome," a signal integration and transduction hub", Science, 322 (5898), 92 (2008), DOI: 10.1126/science.1159572
- Jan Kadlec, Silvia Loureiro, Ian M. Jones, Nicola G. A. Abrescia, David I. Stuart, "The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines", Nature Structural & Molecular Biology, 15 (10), 1024 - 30 (2008), DOI: 10.1038/nsmb.1484
- Andrew Clarke, Ramon Hurtado-Guerrero, Shalini Pathak, Alexander W. Schüttelkopf, Vladimir Borodkin, Sharon M. Shepherd, Adel F. M. Ibrahim, Daan M. F. Van Aalten , "Structural insights into mechanism and specificity of O-GlcNAc transferase", The Embo Journal, 27 (20), 2780 - 2788 (2008), DOI: 10.1038/emboj.2008.186
- Mohammad W. Bahar, Samantha Cooray, Ron A.-J. Chen, Daniel Whalen, Nicola G. A. Abrescia, David Alderton, Raymond J. Owens, Geoffrey L. Smith, Stephen C. Graham, David I. Stuart, Jonathan M. Grimes, "Vaccinia virus proteins A52 and B14 share a Bcl-2–like fold but have evolved to inhibit NF-κB rather than apoptosis", Plos Pathogens, 4 (8) (2008), DOI: 10.1371/journal.ppat.1000128
- [Poster] David Hall, Alun Ashton, Jose Brandao-Neto, David Butler, Elizabeth Duke, Gwyndaf Evans, Ralf Flaig, Andrew Foster, Paul Gibbons, Mic Harding, Mike Latchem, Karl Levik, Katherine Mcauley, James O'Hea, Geoff Preece, James Sandy, Thomas Sorensen, David Waterman, Mark Williams, Richard Woolliscroft, "Macromolecular crystallography at Diamond Light Source: Automation and pathogenic sample environment", Acta Crystallographica Section A, 64, C174 (2008), DOI: 10.1107/S0108767308094440
- M. Kilkenny, A. Dore, K. Nestoras, J. C. Y. Ho, F. Z. Watts, L. Pearl, S. M. Roe, "Structural and functional analysis of the Crb2–BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair", Genes And Development, 22 (15), 2034-2047 (2008), DOI: 10.1101/gad.472808
- [Conference Paper] Ralf Flaig, Alun Ashton, Jose Brandao-Neto, Liz Duke, Gwyndaf Evans, Andrew Foster, Paul Gibbons, A. Grant, David Hall, Mike Latchem, Karl Levik, Katherine Mcauley, James O'Hea, Geoff Preece, James Sandy, Thomas Sorensen, David Waterman, Richard Woolliscroft, "Experience from operation and commissioning of the Phase 1 MX beamlines at Diamond Light Source" (2008)
- M. L. H. Chu, L. M. G. Chavas, K. T. Douglas, P. A. Eyers, L. Tabernero, "Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125", Journal Of Biological Chemistry, 283 (31), 21495 - 21500 (2008), DOI: 10.1074/jbc.M803026200
- Tobias Stuwe, Michael Hothorn, Erwan Lejeune, Vladimir Rybin, Miriam Bortfeld, Klaus Scheffzek, Andreas Ladurner, "The FACT Spt16 'peptidase' domain is a histone H3'H4 binding module", Proceedings Of The National Academy Of Sciences, 105 (26), 8884-8889 (2008), DOI: 10.1073/pnas.0712293105
- Huntang Liu, Jana Rudolf, Kenneth A. Johnson, Stephen A. Mcmahon, Muse Oke, Lester Carter, Anne-Marrie Mcrobbie, Sara E. Brown, Malcolm F. White, James H. Naismith, "Structure of the DNA repair helicase XPD", Cell, 133 (5), 801 - 822 (2008), DOI: 10.1016/j.cell.2008.04.029
- Marc Fiedler, María José Sánchez-Barrena, Maxim Nekrasov, Juliusz Mieszczanek, Vladimir Rybin, Jürg Müller, Phil Evans, Mariann Bienz, "Decoding of methylated histone H3 tail by the pygo-BCL9 Wnt signaling complex", Molecular Cell, 30 (4), 507 - 518 (2008), DOI: 10.1016/j.molcel.2008.03.011
- Janet E. Deane, Pietro Roversi, Carole King, Steven Johnson, Susan M. Lea, "Structures of the Shigella flexneriType 3 secretion system protein MxiC reveal conformational variability amongst homologues", Journal Of Molecular Biology, 377 (4), 985 - 992 (2008), DOI: 10.1016/j.jmb.2008.01.072
- Wei Li, Ty E. Adams, Jyoti Nangalia, Charles T. Esmon, James A. Huntington, "Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex", Proceedings Of The National Academy Of Sciences, 105 (12), 4661 - 6 (2008), DOI: 10.1073/pnas.0711055105
- [Poster] Ivan Laponogov, Maninder Sohi, Dennis Veselkov, Xiao-Su Pan, Ritica Sawhney, Andrew Thompson, L . Mark Fisher, Mark Sanderson, "Structure of the topoisomerase IV from S. pneumoniae with a DNA target and quinolone drug", Acta Crystallographica Section A Foundations of Crystallography, 64, C307 (2008)
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
Diamond Light Source Ltd
Diamond House
Harwell Science & Innovation Campus
Didcot
Oxfordshire
OX11 0DE
Copyright © Diamond Light Source. Diamond Light Source® and the Diamond logo are registered trademarks of Diamond Light Source Ltd
Registered in England and Wales at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom. Company number: 4375679. VAT number: 287 461 957. Economic Operators Registration and Identification (EORI) number: GB287461957003.