Instruments by Science Group
Macromolecular
Soft Condensed 
Imaging and
Biological
Magnetic
Structures and
Crystallography 
Spectroscopy B21 Contact
Beamline phone numbers:
+44 (0) 1235 77 8627
+44 (0) 1235 77 8640
Principal Beamline Scientist:
Nathan Cowieson
Tel: +44 (0) 1235 567 504
E-mail: [email protected]
Science Group Leader
Robert Rambo
Email: [email protected]
Tel: +44 (0)1235 56 7675
B21 High Throughput SAXS
Status: Operational
Beamsize: <75 μm
Detector: Eiger 4M
Energy: 6 - 23 keV
Detector: Eiger 4M
Energy: 6 - 23 keV
70 items found for 2023 [total: 654]
Effect of steam sterilisation on physico-chemical properties of antibacterial covalently cross-linked ε-polylysine/hyaluronic acid hydrogels Carbohydrate Polymer Technologies And Applications, 6 Dec 2023 DOI: 10.1016/j.carpta.2023.100363
Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane Nature Communications, 14 Dec 2023 DOI: 10.1038/s41467-023-43585-5
Intercepting the inflammation signal Nov 2023
Science Highlight B21-High Throughput SAXS
tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut Nucleic Acids Research, Nov 2023 DOI: 10.1093/nar/gkad1188
Accurate and efficient SAXS/SANS implementation including solvation layer effects suitable for molecular simulations Journal Of Chemical Theory And Computation, Nov 2023 DOI: 10.1021/acs.jctc.3c00864
Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer Angewandte Chemie International Edition, Nov 2023 DOI: 10.1002/anie.202312517
Contactin 2 homophilic adhesion structure and conformational plasticity Structure, 11 Nov 2023 DOI: 10.1016/j.str.2023.10.012
The SKMT Algorithm: A method for assessing and comparing underlying protein entanglement Plos Computational Biology, 19 Nov 2023 DOI: 10.1371/journal.pcbi.1011248
X-ray structure of the metastable SEPT14–SEPT7 coiled coil reveals a hendecad region crucial for heterodimerization Acta Crystallographica Section D Structural Biology, 79 Oct 2023 DOI: 10.1107/S2059798323006514
Structure and function of Campylobacter jejuni polynucleotide phosphorylase (PNPase): Insights into the role of this RNase in pathogenicity Biochimie, 34 Oct 2023 DOI: 10.1016/j.biochi.2023.10.006
The solution structure of the heavy chain-only C5-Fc nanobody reveals exposed variable regions that are optimal for COVID-19 antigen interactions Journal Of Biological Chemistry, 363 Oct 2023 DOI: 10.1016/j.jbc.2023.105337
Compounds derived from Humulus lupulus inhibit SARS-CoV-2 papain-like protease and virus replication Phytomedicine, 80 Oct 2023 DOI: 10.1016/j.phymed.2023.155176
Journal Paper B21-High Throughput SAXS
An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function Nature Communications, 14 Oct 2023 DOI: 10.1038/s41467-023-41890-7
Modular bioorthogonal lipid nanoparticle modification platforms for cardiac homing Journal Of The American Chemical Society, Oct 2023 DOI: 10.1021/jacs.3c07811
Micro/nano-patterns for enhancing differentiation of human neural stem cells and fabrication of nerve conduits via soft lithography and 3D printing Biomaterials Advances, 15 Oct 2023 DOI: 10.1016/j.bioadv.2023.213653
Journal Paper B21-High Throughput SAXS
An enhanced biophysical screening strategy to investigate the affinity of ASOs for their target RNA Rsc Chemical Biology, 16 Oct 2023 DOI: 10.1039/D3CB00072A
Unveiling protein-protein interaction potential through Monte Carlo simulation combined with small-angle X-ray scattering International Journal Of Biological Macromolecules, 248 Sept 2023 DOI: 10.1016/j.ijbiomac.2023.125869
Journal Paper B21-High Throughput SAXS
Oligomeric state of β-coronavirus non-structural protein 10 stimulators studied by small angle X-ray scattering International Journal Of Molecular Sciences, 24 Sept 2023 DOI: 10.3390/ijms241713649
Crystal structure and solution state of the C-terminal head region of the narmovirus receptor binding protein Mbio, Sept 2023 DOI: 10.1128/mbio.01391-23
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography I04-Macromolecular Crystallography open access
The solution structure of the unbound IgG Fc receptor CD64 resembles its crystal structure: Implications for function Plos One, 18 Sept 2023 DOI: 10.1371/journal.pone.0288351
Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation Science, 381 Sept 2023 DOI: 10.1126/science.add7859
Journal Paper B21-High Throughput SAXS
Biophysical and biochemical characterization of an HBV cccDNA g-quadruplex targeting therapeutic Sept 2023
Thesis B21-High Throughput SAXS
Stretching the chains: the destabilizing impact of Cu 2+ and Zn 2+ ions on K48-linked diubiquitin Dalton Transactions, 22 Aug 2023 DOI: 10.1039/D3DT01815F
Journal Paper B21-High Throughput SAXS
The examination of extracellular matrix macromolecular components via the structural and biophysical hybrid method approach Aug 2023
Thesis B21-High Throughput SAXS
Structural studies of pH effects on botulinum toxins A & E Aug 2023
Thesis B21-High Throughput SAXS
Phage T3 overcomes the BREX defense through SAM cleavage and inhibition of SAM synthesis by SAM lyase Cell Reports, 42 Aug 2023 DOI: 10.1016/j.celrep.2023.112972
Intramolecular structural heterogeneity altered by long-range contacts in an intrinsically disordered protein Proceedings Of The National Academy Of Sciences, 120 Jul 2023 DOI: 10.1073/pnas.2220180120
Journal Paper B21-High Throughput SAXS
Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179 Science Signaling, 16 Jul 2023 DOI: 10.1126/scisignal.add9539
Journal Paper B21-High Throughput SAXS
Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: implication in AADC deficiency Protein Science, Jul 2023 DOI: 10.1002/pro.4732
Contacts in the nervous system: Structural insights into contactin mediated neural adhesion & signaling Jul 2023
Thesis B21-High Throughput SAXS I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography
Histone divergence in trypanosomes results in unique alterations to nucleosome structure Nucleic Acids Research, 251 Jul 2023 DOI: 10.1093/nar/gkad577
Molecular basis of the final step of cell division in Streptococcus pneumoniae Cell Reports, 42 Jul 2023 DOI: 10.1016/j.celrep.2023.112756
Effect of glycosylation on self-assembly of lipid A lipopolysaccharides in aqueous solutions Langmuir, 10 June 2023 DOI: 10.1021/acs.langmuir.3c00828
The structure of Leptospira interrogans GAPDH sheds light into an immunoevasion factor that can target the anaphylatoxin C5a of innate immunity Frontiers In Immunology, 14 June 2023 DOI: 10.3389/fimmu.2023.1190943
DNA-templated self-assembly of bradykinin into bioactive nanofibrils Soft Matter, June 2023 DOI: 10.1039/D3SM00431G
Journal Paper B21-High Throughput SAXS
Structural basis for DARC binding in reticulocyte invasion by Plasmodium vivax Nature Communications, 14 June 2023 DOI: 10.1038/s41467-023-39357-w
Journal Paper B21-High Throughput SAXS I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
New approaches to small angle scattering methods for studying α-synuclein and other protein aggregation June 2023
Thesis B21-High Throughput SAXS
Nanomaterials for membrane protein biology June 2023
Thesis B21-High Throughput SAXS I07-Surface & interface diffraction I22-Small angle scattering & Diffraction
Molecular insights into LINC complex architecture through the crystal structure of a luminal trimeric coiled-coil domain of SUN1 Frontiers In Cell And Developmental Biology, 11 June 2023 DOI: 10.3389/fcell.2023.1144277
Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate Frontiers In Chemistry, 11 May 2023 DOI: 10.3389/fchem.2023.1113885
Histidine-containing amphiphilic peptide-based non-cytotoxic hydrogelator with antibacterial activity and sustainable drug release Langmuir, May 2023 DOI: 10.1021/acs.langmuir.3c00235
Journal Paper B21-High Throughput SAXS
Autophagy receptor NDP52 alters DNA conformation to modulate RNA polymerase II transcription Nature Communications, 14 May 2023 DOI: 10.1038/s41467-023-38572-9
Chemically cross-linked hydrogels from repetitive protein arrays Journal Of Structural Biology, 25 May 2023 DOI: 10.1016/j.jsb.2023.107981
A diverse array of large capsules transform in response to stimuli Journal Of The American Chemical Society, May 2023 DOI: 10.1021/jacs.3c02491
Mapping and characterization of G‐quadruplexes in monkeypox genomes Journal Of Medical Virology, 95 May 2023 DOI: 10.1002/jmv.28783
Self-sorting in diastereomeric mixtures of functionalized dipeptides Biomacromolecules, May 2023 DOI: 10.1021/acs.biomac.3c00246
Molecular structure of soluble vimentin tetramers Scientific Reports, 13 May 2023 DOI: 10.1038/s41598-023-34814-4
Harnessing the power of cryo electron microscopy to visualise a full-length kinesin KIFC1 (HSET) May 2023
Thesis B21-High Throughput SAXS Krios I-Titan Krios I at Diamond
Effect of charge on molecular self-assembly, nanoscopic and bulk material properties of ultra-short peptides Apr 2023
Conference Paper B21-High Throughput SAXS
Sample preparation of atherosclerotic plaque for SAXS/WAXS experimentation Acs Omega, Apr 2023 DOI: 10.1021/acsomega.3c00060
Journal Paper B21-High Throughput SAXS labSAXS-Offline SAXS and Sample Environment Development open access
Systematic construction of progressively larger capsules from a fivefold linking pyrrole-based subcomponent Nature Synthesis, 115 Apr 2023 DOI: 10.1038/s44160-023-00276-9
New studies towards lignin valorisation Apr 2023
Science Highlight B21-High Throughput SAXS I03-Macromolecular Crystallography I23-Long wavelength MX
The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation Nature Communications, 14 Mar 2023 DOI: 10.1038/s41467-023-36692-w
Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases Nature Communications, 14 Mar 2023 DOI: 10.1038/s41467-023-37215-3
Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein Acta Crystallographica Section F Structural Biology Communications, 79 Mar 2023 DOI: 10.1107/S2053230X23000717
Investigating RNA–RNA interactions through computational and biophysical analysis Nucleic Acids Research, 24 Mar 2023 DOI: 10.1093/nar/gkad223
Exploring processes to improve electroactivity in Shewanella oneidensis MR-1 Mar 2023
Thesis B21-High Throughput SAXS
Stabilization of the dimeric state of SARS-CoV-2 main protease by GC376 and Nirmatrelvir International Journal Of Molecular Sciences, 24 Mar 2023 DOI: 10.3390/ijms24076062
eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation Nucleic Acids Research, 168 Feb 2023 DOI: 10.1093/nar/gkad030
Charge regulation of poly(acrylic acid) in solutions of non-charged polymer and colloids Polymers, 15 Feb 2023 DOI: 10.3390/polym15051121
New insights on the release and self-healing model of stimuli-sensitive liposomes Journal Of Colloid And Interface Science, 12 Feb 2023 DOI: 10.1016/j.jcis.2023.02.099
Journal Paper B21-High Throughput SAXS
TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life Mabs, 15 Feb 2023 DOI: 10.1080/19420862.2022.2160229
Effect of cholesterol on the structure and composition of glyco-DIBMA lipid particles Langmuir, Feb 2023 DOI: 10.1021/acs.langmuir.2c03019
Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation Proceedings Of The National Academy Of Sciences, 120 Jan 2023 DOI: 10.1073/pnas.2212246120
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I23-Long wavelength MX open access
A cysteine pair controls flavin reduction by extracellular cytochromes during anoxic/oxic environmental transitions Mbio, Jan 2023 DOI: 10.1128/mbio.02589-22
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3 Nature Structural & Molecular Biology, 7 Jan 2023 DOI: 10.1038/s41594-022-00909-1
Journal Paper B21-High Throughput SAXS
Bio-SAXS of single-stranded DNA-binding proteins: radiation protection by the compatible solute ectoine Physical Chemistry Chemical Physics, 49 Jan 2023 DOI: 10.1039/D2CP05053F
Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome Life Science Alliance, 6 Jan 2023 DOI: 10.26508/lsa.202201588
Staphylococcal Periscope Proteins Aap, SasG and Pls project non-canonical legume-like lectin adhesin domains from the bacterial surface Journal Of Biological Chemistry, 350 Jan 2023 DOI: 10.1016/j.jbc.2023.102936
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) open access
Biophysical characterization of the structure of a SARS-CoV-2 self-amplifying RNA (saRNA) vaccine Biology Methods And Protocols, 8 Jan 2023 DOI: 10.1093/biomethods/bpad001
- Artemijs Sceglovs, Jacek K. Wychowaniec, Ingus Skadins, Aigars Reinis, Charlotte Edwards-Gayle, Matteo D'Este, Kristine Salma-Ancane, "Effect of steam sterilisation on physico-chemical properties of antibacterial covalently cross-linked ε-polylysine/hyaluronic acid hydrogels", Carbohydrate Polymer Technologies And Applications, 6 (2023), DOI: 10.1016/j.carpta.2023.100363
- Amaia González-Magaña, Igor Tascon, Jon Altuna-Alvarez, María Queralt-Martín, Jake Colautti, Carmen Velázquez, Maialen Zabala, Jessica Rojas-Palomino, Marité Cárdenas, Antonio Alcaraz, John C. Whitney, Iban Ubarretxena-Belandia, David Albesa-Jove, "Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane", Nature Communications, 14 (2023), DOI: 10.1038/s41467-023-43585-5
- [Science Highlight] Diamond Light Source, "Intercepting the inflammation signal" (2023)
- Natalie Krahn, Jingji Zhang, Sergey V. Melnikov, Jeffery Tharp, Alessandra Villa, Armaan Patel, Rebecca J. Howard, Haben Gabir, Trushar R. Patel, Jörg Stetefeld, Joseph Puglisi, Dieter Söll, "tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut", Nucleic Acids Research (2023), DOI: 10.1093/nar/gkad1188
- Federico Ballabio, Cristina Paissoni, Michela Bollati, Matteo De Rosa, Riccardo Capelli, Carlo Camilloni, "Accurate and efficient SAXS/SANS implementation including solvation layer effects suitable for molecular simulations", Journal Of Chemical Theory And Computation (2023), DOI: 10.1021/acs.jctc.3c00864
- Francesco Rinaldi, Fabrizio Schipani, Beatrice Balboni, Federico Catalano, Roberto Marotta, Samuel H. Myers, Viola Previtali, Marina Veronesi, Luigi Scietti, Valentina Cecatiello, Sebastiano Pasqualato, Jose Antonio Ortega, Stefania Girotto, Andrea Cavalli, "Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer", Angewandte Chemie International Edition (2023), DOI: 10.1002/anie.202312517
- Lucas M. P. Chataigner, Lena Thärichen, J. Wouter Beugelink, Joke C. M. Granneman, Nadia J. Mokiem, Joost Snijder, Friedrich Förster, Bert J. C. Janssen, "Contactin 2 homophilic adhesion structure and conformational plasticity", Structure, 11 (2023), DOI: 10.1016/j.str.2023.10.012
- Arron Bale, Robert Rambo, Christopher Prior, "The SKMT Algorithm: A method for assessing and comparing underlying protein entanglement", Plos Computational Biology, 19 (2023), DOI: 10.1371/journal.pcbi.1011248
- Italo A. Cavini, Ashley J. Winter, Humberto D'Muniz Pereira, Derek N. Woolfson, Matthew P. Crump, Richard C. Garratt, "X-ray structure of the metastable SEPT14–SEPT7 coiled coil reveals a hendecad region crucial for heterodimerization", Acta Crystallographica Section D Structural Biology, 79 (2023), DOI: 10.1107/S2059798323006514
- Cátia Bárria, Diogo Athayde, Guillem Hernandez, Leonor Fonseca, Jorge Casinhas, Tiago N. Cordeiro, Margarida Archer, Cecília M. Arraiano, Jose A. Brito, Rute G. Matos, "Structure and function of Campylobacter jejuni polynucleotide phosphorylase (PNPase): Insights into the role of this RNase in pathogenicity", Biochimie, 34 (2023), DOI: 10.1016/j.biochi.2023.10.006
- Xin Gao, Joseph W. Thrush, Jayesh Gor, James H. Naismith, Raymond J. Owens, Stephen J. Perkins, "The solution structure of the heavy chain-only C5-Fc nanobody reveals exposed variable regions that are optimal for COVID-19 antigen interactions", Journal Of Biological Chemistry, 363 (2023), DOI: 10.1016/j.jbc.2023.105337
- Anna-Maria Herzog, Katharina Göbel, Luigi Marongiu, Natalia Ruetalo, Marta Campos Alonso, Christian Leischner, Christian Busch, Markus Burkard, Ulrich M. Lauer, Paul P. Geurink, Klaus-Peter Knobeloch, Michael Schindler, Guenter Fritz, Sascha Venturelli, "Compounds derived from Humulus lupulus inhibit SARS-CoV-2 papain-like protease and virus replication", Phytomedicine, 80 (2023), DOI: 10.1016/j.phymed.2023.155176
- Hipólito Nicolás Cuesta-Hernández, Julia Contreras, Pablo Soriano-Maldonado, Jana Sánchez-Wandelmer, Wayland Yeung, Ana Martín-Hurtado, Ines G. Munoz, Natarajan Kannan, Marta Llimargas, Javier Muñoz, Ivan Plaza-Menacho, "An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function", Nature Communications, 14 (2023), DOI: 10.1038/s41467-023-41890-7
- Raquel Cruz-Samperio, Corrigan L. Hicks, Aaron Scott, Ignacio Gispert Contamina, Yuval Elani, Rebecca J. Richardson, Adam W. Perriman, "Modular bioorthogonal lipid nanoparticle modification platforms for cardiac homing", Journal Of The American Chemical Society (2023), DOI: 10.1021/jacs.3c07811
- Jagoda Litowczenko, Jacek K. Wychowaniec, Karol Załęski, Łukasz Marczak, Charlotte J. C. Edwards-Gayle, Krzysztof Tadyszak, Barbara M. Maciejewska, "Micro/nano-patterns for enhancing differentiation of human neural stem cells and fabrication of nerve conduits via soft lithography and 3D printing", Biomaterials Advances, 15 (2023), DOI: 10.1016/j.bioadv.2023.213653
- Rouven Stulz, Michael Lerche, Olivia Luige, Agnes Taylor, Stefan Geschwindner, Alice Ghidini, "An enhanced biophysical screening strategy to investigate the affinity of ASOs for their target RNA", Rsc Chemical Biology, 16 (2023), DOI: 10.1039/D3CB00072A
- Fernando T. Tanouye, Jozismar R. Alves, Francesco Spinozzi, Rosangela Itri, "Unveiling protein-protein interaction potential through Monte Carlo simulation combined with small-angle X-ray scattering", International Journal Of Biological Macromolecules, 248 (2023), DOI: 10.1016/j.ijbiomac.2023.125869
- Wolfgang Knecht, S. Zoë Fisher, Jiaqi Lou, Céleste Sele, Shumeng Ma, Anna Andersson Rasmussen, Nikos Pinotsis, Frank Kozielski, "Oligomeric state of β-coronavirus non-structural protein 10 stimulators studied by small angle X-ray scattering", International Journal Of Molecular Sciences, 24 (2023), DOI: 10.3390/ijms241713649
- Alice J. Stelfox, Kasopefoluwa Y. Oguntuyo, Ilona Rissanen, Karl Harlos, Robert Rambo, Benhur Lee, Thomas Bowden, "Crystal structure and solution state of the C-terminal head region of the narmovirus receptor binding protein", Mbio (2023), DOI: 10.1128/mbio.01391-23
- Gar Kay Hui, Xin Gao, Jayesh Gor, Jinghua Lu, Peter D. Sun, Stephen J. Perkins, "The solution structure of the unbound IgG Fc receptor CD64 resembles its crystal structure: Implications for function", Plos One, 18 (2023), DOI: 10.1371/journal.pone.0288351
- Pauline Juyoux, Ioannis Galdadas, Dorothea Gobbo, Jill Von Velsen, Martin Pelosse, Mark D. Tully, Oscar Vadas, Francesco Luigi Gervasio, Erika Pellegrini, Matthew W. Bowler, "Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation", Science, 381, 1217 - 1225 (2023), DOI: 10.1126/science.add7859
- [Thesis] Gerardo K. Balderas Figueroa, "Biophysical and biochemical characterization of an HBV cccDNA g-quadruplex targeting therapeutic" (2023)
- Vincenzo Mangini, Giulia Grasso, Benny D. Belviso, Michele F. M. Sciacca, Valeria Lanza, Rocco Caliandro, Danilo Milardi, "Stretching the chains: the destabilizing impact of Cu 2+ and Zn 2+ ions on K48-linked diubiquitin", Dalton Transactions, 22 (2023), DOI: 10.1039/D3DT01815F
- [Thesis] Fabian Heide, "The examination of extracellular matrix macromolecular components via the structural and biophysical hybrid method approach" (2023)
- [Thesis] Christophe J. Lalaurie, "Structural studies of pH effects on botulinum toxins A & E" (2023)
- Aleksandr Andriianov, Silvia Triguis, Alena Drobiazko, Nicolas Sierro, Nikolai V. Ivanov, Maria Selmer, Konstantin Severinov, Artem Isaev, "Phage T3 overcomes the BREX defense through SAM cleavage and inhibition of SAM synthesis by SAM lyase", Cell Reports, 42 (2023), DOI: 10.1016/j.celrep.2023.112972
- Gil Koren, Sagi Meir, Lennard Holschuh, Haydyn D. T. Mertens, Tamara Ehm, Nadav Yahalom, Adina Golombek, Tal Schwartz, Dmitri I. Svergun, Omar A. Saleh, Joachim Dzubiella, Roy Beck, "Intramolecular structural heterogeneity altered by long-range contacts in an intrinsically disordered protein", Proceedings Of The National Academy Of Sciences, 120 (2023), DOI: 10.1073/pnas.2220180120
- Dipak N. Patil, Serena Pantalone, Yan Cao, Thibaut Laboute, Scott J. Novick, Shikha Singh, Simone Savino, Silvia Faravelli, Francesca Magnani, Patrick R. Griffin, Appu K. Singh, Federico Forneris, Kirill A. Martemyanov, "Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179", Science Signaling, 16 (2023), DOI: 10.1126/scisignal.add9539
- Giovanni Bisello, Rui P. Ribeiro, Massimiliano Perduca, Benny D. Belviso, Patrizia Polverino De' Laureto, Alejandro Giorgetti, Rocco Caliandro, Mariarita Bertoldi, "Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: implication in AADC deficiency", Protein Science (2023), DOI: 10.1002/pro.4732
- [Thesis] Lucas M. P. Chataigner, "Contacts in the nervous system: Structural insights into contactin mediated neural adhesion & signaling" (2023)
- Gauri Deák, Hannah Wapenaar, Gorka Sandoval, Ruofan Chen, Mark r. D. Taylor, Hayden Burdett, James A. Watson, Maarten W. Tuijtel, Shaun Webb, Marcus D. Wilson, "Histone divergence in trypanosomes results in unique alterations to nucleosome structure", Nucleic Acids Research, 251 (2023), DOI: 10.1093/nar/gkad577
- Siseth Martínez-Caballero, Céline Freton, Rafael Molina, Sergio G. Bartual, Virginie Gueguen-Chaignon, Chryslène Mercy, Federico Gago, Kiran V. Mahasenan, Ines G. Munoz, Mijoon Lee, Dusan Hesek, Shahriar Mobashery, Juan A. Hermoso, Christophe Grangeasse, "Molecular basis of the final step of cell division in Streptococcus pneumoniae", Cell Reports, 42 (2023), DOI: 10.1016/j.celrep.2023.112756
- Valeria Castelletto, Jani Seitsonen, Ian W. Hamley, "Effect of glycosylation on self-assembly of lipid A lipopolysaccharides in aqueous solutions", Langmuir, 10 (2023), DOI: 10.1021/acs.langmuir.3c00828
- Sergio Navas-Yuste, Karla De La Paz, Javier Querol-García, Sara Gómez-Quevedo, Santiago Rodríguez De Córdoba, Francisco J. Fernández, M. Cristina Vega, "The structure of Leptospira interrogans GAPDH sheds light into an immunoevasion factor that can target the anaphylatoxin C5a of innate immunity", Frontiers In Immunology, 14 (2023), DOI: 10.3389/fimmu.2023.1190943
- Thiago Da Costa Lourenço, Lucas Mello, Marcelo Y. Icimoto, Renata N. Bicev, Ian Hamley, Valeria Castelletto, Clovis R. Nakaie, Emerson R. Da Silva, "DNA-templated self-assembly of bradykinin into bioactive nanofibrils", Soft Matter (2023), DOI: 10.1039/D3SM00431G
- Re'Em Moskovitz, Tossapol Pholcharee, Sophia M. Donvito, Bora Guloglu, Edward Lowe, Franziska Mohring, Robert W. Moon, Matthew Higgins, "Structural basis for DARC binding in reticulocyte invasion by Plasmodium vivax", Nature Communications, 14 (2023), DOI: 10.1038/s41467-023-39357-w
- [Thesis] Han Yin, "New approaches to small angle scattering methods for studying α-synuclein and other protein aggregation" (2023)
- [Thesis] Eleonore Mason, "Nanomaterials for membrane protein biology" (2023)
- Manickam Gurusaran, Jelle J. Biemans, Christopher W. Wood, Owen R. Davies, "Molecular insights into LINC complex architecture through the crystal structure of a luminal trimeric coiled-coil domain of SUN1", Frontiers In Cell And Developmental Biology, 11 (2023), DOI: 10.3389/fcell.2023.1144277
- Philip Bardelang, Ewan J. Murray, Isobel Blower, Sara Zandomeneghi, Alice Goode, Rohanah Hussain, Divya Kumari, Giuliano Siligardi, Katsuaki Inoue, Jeni Luckett, James Doutch, Jonas Emsley, Weng C. Chan, Philip Hill, Paul Williams, Boyan B. Bonev, "Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate", Frontiers In Chemistry, 11 (2023), DOI: 10.3389/fchem.2023.1113885
- Biswanath Hansda, Jhilam Majumder, Biplab Mondal, Akash Chatterjee, Subhadeep Das, Sourav Kumar, Ratan Gachhui, Valeria Castelletto, Ian W. Hamley, Prosenjit Sen, Arindam Banerjee, "Histidine-containing amphiphilic peptide-based non-cytotoxic hydrogelator with antibacterial activity and sustainable drug release", Langmuir (2023), DOI: 10.1021/acs.langmuir.3c00235
- Ália Dos Santos, Daniel E. Rollins, Yukti Hari-Gupta, Hannah Mcarthur, Mingxue Du, Sabrina Yong Zi Ru, Kseniia Pidlisna, Ane Stranger, Faeeza Lorgat, Danielle Lambert, Ian Brown, Kevin Howland, Jesse Aaron, Lin Wang, Peter J. I. Ellis, Teng-Leong Chew, Marisa Martin-Fernandez, Alice L. B. Pyne, Christopher P. Toseland, "Autophagy receptor NDP52 alters DNA conformation to modulate RNA polymerase II transcription", Nature Communications, 14 (2023), DOI: 10.1038/s41467-023-38572-9
- Rossana Boni, Elizabeth A. Blackburn, Dirk-Jan Kleinjan, Mantas Jonaitis, Flora Hewitt-Harris, Megan Murdoch, Susan Rosser, David C. Hay, Lynne Regan, "Chemically cross-linked hydrogels from repetitive protein arrays", Journal Of Structural Biology, 25 (2023), DOI: 10.1016/j.jsb.2023.107981
- Kai Wu, Tanya K. Ronson, Leonard Goh, Weichao Xue, Andrew W. Heard, Pingru Su, Xiaopeng Li, Mladen Vinković, Jonathan R. Nitschke, "A diverse array of large capsules transform in response to stimuli", Journal Of The American Chemical Society (2023), DOI: 10.1021/jacs.3c02491
- Higor Sette Pereira, Darren L. Gemmill, M. Quadir Siddiqui, Gunjan Vasudeva, Trushar R. Patel, "Mapping and characterization of G‐quadruplexes in monkeypox genomes", Journal Of Medical Virology, 95 (2023), DOI: 10.1002/jmv.28783
- Qingwen Guan, Kate Mcaulay, Tian Xu, Sarah E. Rogers, Charlotte Edwards-Gayle, Ralf Schweins, Honggang Cui, Annela M. Seddon, Dave J. Adams, "Self-sorting in diastereomeric mixtures of functionalized dipeptides", Biomacromolecules (2023), DOI: 10.1021/acs.biomac.3c00246
- Pieter-Jan Vermeire, Anastasia V. Lilina, Hani M. Hashim, Lada Dlabolová, Jan Fiala, Steven Beelen, Zdeněk Kukačka, Jeremy N. Harvey, Petr Novák, Sergei V. Strelkov, "Molecular structure of soluble vimentin tetramers", Scientific Reports, 13 (2023), DOI: 10.1038/s41598-023-34814-4
- [Thesis] Varun Ramaswamy, "Harnessing the power of cryo electron microscopy to visualise a full-length kinesin KIFC1 (HSET)" (2023)
- [Conference Paper] Mohamed Elsawy, Mohamed Soliman, Abdulwahhab Khedr, Charlotte Edwards-Gayle, Jacek Wychowaniec, "Effect of charge on molecular self-assembly, nanoscopic and bulk material properties of ultra-short peptides" (2023)
- Rebecca R. Mackley, Steven Huband, Tara L. Schiller, "Sample preparation of atherosclerotic plaque for SAXS/WAXS experimentation", Acs Omega (2023), DOI: 10.1021/acsomega.3c00060
- Kai Wu, Tanya K. Ronson, Pingru Su, Zhi Chen, Leonard Goh, Andrew W. Heard, Xiaopeng Li, Fabian Klautzsch, Christoph A. Schalley, Mladen Vinković, Jonathan R. Nitschke, "Systematic construction of progressively larger capsules from a fivefold linking pyrrole-based subcomponent", Nature Synthesis, 115 (2023), DOI: 10.1038/s44160-023-00276-9
- [Science Highlight] Diamond Light Source, "New studies towards lignin valorisation" (2023)
- Markus Meier, Monika Gupta, Serife Akgül, Matthew Mcdougall, Thomas Imhof, Denise Nikodemus, Raphael Reuten, Aniel Moya-Torres, Vu To, Fraser Ferens, Fabian Heide, Gay P. Padilla-Meier, Philipp Kukura, Wenming Huang, Birgit Gerisch, Matthias Mörgelin, Kate Poole, Adam Antebi, Manuel Koch, Jörg Stetefeld, "The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation", Nature Communications, 14 (2023), DOI: 10.1038/s41467-023-36692-w
- Beatriz Trastoy, Jonathan J. Du, Javier O. Cifuente, Lorena Rudolph, Mikel Garcia-Alija, Erik H. Klontz, Daniel Deredge, Nazneen Sultana, Chau G. Huynh, Maria W. Flowers, Chao Li, Diego E. Sastre, Lai-Xi Wang, Francisco Corzana, Alvaro Mallagaray, Eric J. Sundberg, Marcelo E. Guerin, "Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases", Nature Communications, 14 (2023), DOI: 10.1038/s41467-023-37215-3
- Jack D. Whitehead, Jonathan M. Grimes, Jeremy R. Keown, "Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein", Acta Crystallographica Section F Structural Biology Communications, 79 (2023), DOI: 10.1107/S2053230X23000717
- Tyler Mrozowich, Sean M. Park, Maria Waldl, Amy Henrickson, Scott Tersteeg, Corey r. Nelson, Anneke De Klerk, Borries Demeler, Ivo l. Hofacker, Michael t. Wolfinger, Trushar R. Patel, "Investigating RNA–RNA interactions through computational and biophysical analysis", Nucleic Acids Research, 24 (2023), DOI: 10.1093/nar/gkad223
- [Thesis] Ana V. Silva, "Exploring processes to improve electroactivity in Shewanella oneidensis MR-1" (2023)
- Alessandro Paciaroni, Valeria Libera, Francesca Ripanti, Andrea Orecchini, Caterina Petrillo, Daniela Francisci, Elisabetta Schiaroli, Samuele Sabbatini, Anna Gidari, Elisa Bianconi, Antonio Macchiarulo, Rohanah Hussain, Lucia Silvestrini, Paolo Moretti, Norhan Belhaj, Matteo Vercelli, Yessica Roque, Paolo Mariani, Lucia Comez, Francesco Spinozzi, "Stabilization of the dimeric state of SARS-CoV-2 main protease by GC376 and Nirmatrelvir", International Journal Of Molecular Sciences, 24 (2023), DOI: 10.3390/ijms24076062
- Tobias Schmidt, Adrianna Dabrowska, Joseph A. Waldron, Kelly Hodge, Grigorios Koulouras, Mads Gabrielsen, June Munro, David C. Tack, Gemma Harris, Ewan Mcghee, David Scott, Leo m. Carlin, Danny Huang, John Le quesne, Sara Zanivan, Ania Wilczynska, Martin Bushell, "eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation", Nucleic Acids Research, 168 (2023), DOI: 10.1093/nar/gkad030
- Evgenee Yekymov, David Attia, Yael Levi-Kalisman, Ronit Bitton, Rachel Yerushalmi-Rozen, "Charge regulation of poly(acrylic acid) in solutions of non-charged polymer and colloids", Polymers, 15 (2023), DOI: 10.3390/polym15051121
- Olga V. Zaborova, Vadim A. Timoshenko, Corinne Nardin, Sergey K. Fillipov, "New insights on the release and self-healing model of stimuli-sensitive liposomes", Journal Of Colloid And Interface Science, 12 (2023), DOI: 10.1016/j.jcis.2023.02.099
- Emma Davé, Oliver Durrant, Neha Dhami, Joanne Compson, Janice Broadbridge, Sophie Archer, Asher Maroof, Kevin Whale, Karelle Menochet, Pierre Bonnaillie, Emily Barry, Gavin Wild, Claude Peerboom, Pallavi Bhatta, Mark Ellis, Matthew Hinchliffe, David P. Humphreys, Sam P. Heywood, "TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life", Mabs, 15 (2023), DOI: 10.1080/19420862.2022.2160229
- Julia Lenz, Andreas Haahr Larsen, Sandro Keller, Alessandra Luchini, "Effect of cholesterol on the structure and composition of glyco-DIBMA lipid particles", Langmuir (2023), DOI: 10.1021/acs.langmuir.2c03019
- Eugene Kuatsjah, Michael Zahn, Xiangyang Chen, Ryo Kato, Daniel J. Hinchen, Mikhail O. Konev, Rui Katahira, Christian Orr, Armin Wagner, Yike Zou, Stefan J. Haugen, Kelsey J. Ramirez, Joshua K. Michener, Andrew R. Pickford, Naofumi Kamimura, Eiji Masai, Kendall N. Houk, John Mcgeehan, Gregg T. Beckham, "Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation", Proceedings Of The National Academy Of Sciences, 120 (2023), DOI: 10.1073/pnas.2212246120
- Michael P. Norman, Marcus J. Edwards, Gaye F. White, Joshua A. J. Burton, Julea N. Butt, David J. Richardson, Ricardo O. Louro, Catarina M. Paquete, Thomas A. Clarke, "A cysteine pair controls flavin reduction by extracellular cytochromes during anoxic/oxic environmental transitions", Mbio (2023), DOI: 10.1128/mbio.02589-22
- James H. Crichton, James M. Dunce, Orla M. Dunne, Lucy J. Salmon, Paul S. Devenney, Jennifer Lawson, Ian R. Adams, Owen R. Davies, "Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3", Nature Structural & Molecular Biology, 7 (2023), DOI: 10.1038/s41594-022-00909-1
- Dorothea C. Hallier, Glen J. Smales, Harald Seitz, Marc Benjamin Hahn, "Bio-SAXS of single-stranded DNA-binding proteins: radiation protection by the compatible solute ectoine", Physical Chemistry Chemical Physics, 49 (2023), DOI: 10.1039/D2CP05053F
- James A. Watson, Raphaël Pantier, Uma Jayachandran, Kashyap Chhatbar, Beatrice Alexander-Howden, Valdeko Kruusvee, Michal Prendecki, Adrian Bird, Atlanta G. Cook, "Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome", Life Science Alliance, 6 (2023), DOI: 10.26508/lsa.202201588
- Laura C. Clark, Kate E. Atkin, Fiona Whelan, Andrew S. Brentnall, Gemma Harris, Aisling M. Towell, Johan P. Turkenburg, Yan Liu, Ten Feizi, Samuel C. Griffiths, Joan A. Geoghegan, Jennifer R. Potts, "Staphylococcal Periscope Proteins Aap, SasG and Pls project non-canonical legume-like lectin adhesin domains from the bacterial surface", Journal Of Biological Chemistry, 350 (2023), DOI: 10.1016/j.jbc.2023.102936
- Daniel Myatt, Lewis Wharram, Charlotte Graham, John Liddell, Harvey Branton, Claire Pizzey, Nathan P. Cowieson, Robert Rambo, Robin J. Shattock, "Biophysical characterization of the structure of a SARS-CoV-2 self-amplifying RNA (saRNA) vaccine", Biology Methods And Protocols, 8 (2023), DOI: 10.1093/biomethods/bpad001
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