• Diamond Home page
  • About
  • For Users
  • Public
  • Industry
  • Instruments
  • Careers
  • More Show more menu items
Search

About

  • About Diamond
  • About Synchrotrons
  • News and Features
  • Events
  • Contact Us
  • FAQ

For Users

  • Apply for beamtime
  • User guide
  • Diamond Users Commitee
  • FAQ
  • User Administration System
  • iSpyB

Industry

  • Techniques Available
  • Industry Research
  • Industry Case Studies
  • News
  • Meet the Industry Team

Science

  • Research
  • Computing
  • The Machine
  • Publications
  • Research Expertise
  • Membrane Protein Laboratory
  • Additional Facilities
  • Publications Database

Instruments

  • Biological Cryo-Imaging
  • Crystallography
  • Imaging and Microscopy
  • Macromolecular Crystallography
  • Magnetic Materials
  • Soft Condensed Matter
  • Spectroscopy
  • Structures and Surfaces

Diamond-II

  • Science
  • Machine
  • Beamlines
  • Software, Control and Computing
  • Infrastructure

Public

  • Public open days
  • School visits
  • Partner with Diamond
  • Explore Diamond

Procurement

  • Non-OJEU Tender Notices
  • OJEU PINs
  • OJEU Tender Notices
  • Registration Form

Careers

  • Vacancies
  • Info for applicants
  • Company Benefits
  • Apprenticeships
  • PhD Studentships
  • Work Placement

Main Content

Soft Condensed Matter - Small Angle Scattering
Sub-navigation
  • Small Angle Scattering
  • Beginner's Guide
  • B21
  • I22
  • labSAXS
  • Software for SAXS
  • Small Angle Scattering Staff
  • Events and Conferences
  • Contacts

In This Section

Sub Navigation
  • Updates on B21
  • Equipment Description
  • Planning Your Experiment
  • Accessing the beamline
  • Staff
  • Publications
  • Science Highlights and News
  • FAQs
  • Accessibility Information

Instruments by Science Group

Macromolecular
Crystallography
Soft Condensed
Matter
Imaging and
Microscopy
Biological
Cryo-Imaging
Magnetic
Materials
Structures and
Surfaces
Crystallography
Spectroscopy

B21 Contact

Beamline phone numbers:
+44 (0) 1235 77 8627
+44 (0) 1235 77 8640

Principal Beamline Scientist: 
Nathan Cowieson

Tel: +44 (0) 1235 567 504
E-mail: [email protected]

More

Science Group Leader

Robert Rambo

Email: [email protected]
Tel: +44 (0)1235 56 7675

B21 High Throughput SAXS

Status: Operational

Beamsize: <75 μm
Detector: Eiger 4M
Energy: 6 - 23 keV

SAXS: Small Angle X-ray Scattering Humidity Control Remote Access Scattering
  1. Instruments
  2. Soft Condensed Matter
  3. Small Angle Scattering
  4. B21
  5. Publications

Publications

2026 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013


47 items found for 2018 [total: 654]


Regulation of human HSC70 ATPase and chaperone activities by Apg2: Role of the acidic subdomain
Yovana Cabrera, Leire Dublang, José Angel Fernández-Higuero, David Albesa-Jove, Maria Lucas, Ana Rosa Viguera, Marcelo E. Guerin, Jose M. G. Vilar, Arturo Muga, Fernando Moro
Journal Of Molecular Biology, Dec 2018 DOI: 10.1016/j.jmb.2018.11.026
Journal Paper B21-High Throughput SAXS
Ferredoxin-linked flavoenzyme defines a family of pyridine nucleotide-independent thioredoxin reductases
Ruben M. Buey, David Fernandez-Justel, Jose M. De Pereda, José L. Revuelta, Peter Schürmann, Bob B. Buchanan, Monica Balsera
Proceedings Of The National Academy Of Sciences, 239 Dec 2018 DOI: 10.1073/pnas.1812781115
Journal Paper B21-High Throughput SAXS I24-Microfocus Macromolecular Crystallography
Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1
James M. Dunce, Amy E. Milburn, Manickam Gurusaran, Irene Da Cruz, Lee T. Sen, Ricardo Benavente, Owen R. Davies
Nature Communications, 9 Dec 2018 DOI: 10.1038/s41467-018-07794-7
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access
Hexameric assembly of the AAA+ protein McrB is necessary for GTPase activity
Neha Nirwan, Pratima Singh, Gyana Gourab Mishra, Christopher M. Johnson, Mark D. Szczelkun, Katsuaki Inoue, Kutti R. Vinothkumar, Kayarat Saikrishnan
Nucleic Acids Research, 57 Dec 2018 DOI: 10.1093/nar/gky1170
Journal Paper B21-High Throughput SAXS open access
Interactome rewiring following pharmacological targeting of BET bromodomains
Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D. R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras
Molecular Cell, Dec 2018 DOI: 10.1016/j.molcel.2018.11.006
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Biochemical characterization and low-resolution SAXS structure of two-domain endoglucanase BlCel9 from Bacillus licheniformis
Evandro Ares De Araújo, Mário De Oliveira Neto, Igor Polikarpov
Applied Microbiology And Biotechnology, 111 Dec 2018 DOI: 10.1007/s00253-018-9508-1
Journal Paper B21-High Throughput SAXS
Measurement of forces between supported cationic bilayers by colloid probe atomic force microscopy: electrolyte concentration and composition
Matthew Leivers, John M. Seddon, Marc Declercq, Eric S. J. Robles, Paul Frederick Luckham
Langmuir, Dec 2018 DOI: 10.1021/acs.langmuir.8b03555
Journal Paper B21-High Throughput SAXS
Interaction of the gtpase elongation factor Like-1 with the Shwachman-Diamond Syndrome protein and its missense mutations
Abril Gijsbers, Diana Montagut, Alfonso Méndez-Godoy, Davide Altamura, Michele Saviano, Dritan Siliqi, Nuria Sánchez-Puig
International Journal Of Molecular Sciences, 19 Dec 2018 DOI: 10.3390/ijms19124012
Journal Paper B21-High Throughput SAXS open access
Amino-acid-based metallo-hydrogel that acts like an esterase
Kousik Gayen, Kingshuk Basu, Dipayan Bairagi, Valeria Castelletto, Ian W. Hamley, Arindam Banerjee
Acs Applied Bio Materials, Nov 2018 DOI: 10.1021/acsabm.8b00513
Journal Paper B21-High Throughput SAXS
A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity
Marta Compte, Seandean Lykke Harwood, Ines G. Munoz, Rocio Navarro, Manuela Zonca, Gema Perez-Chacon, Ainhoa Erce-Llamazares, Nekane Merino, Antonio Tapia-Galisteo, Angel M. Cuesta, Kasper Mikkelsen, Eduardo Caleiras, Natalia Nuñez-Prado, M. Angela Aznar, Simon Lykkemark, Jorge Martínez-Torrecuadrada, Ignacio Melero, Francisco J. Blanco, Jorge Bernardino De La Serna, Juan M. Zapata, Laura Sanz, Luis Alvarez-Vallina
Nature Communications, 9 Nov 2018 DOI: 10.1038/s41467-018-07195-w
Journal Paper B21-High Throughput SAXS open access
Structural variability of EspG chaperones from mycobacterial ESX-1, ESX-3 and ESX-5 Type VII secretion systems
Anne T. Tuukkanen, Diana Freire, Sum Chan, Mark A. Arbing, Robert W. Reed, Timothy J. Evans, Grasilda Zenkeviciutė, Jennifer Kim, Sara Kahng, Michael R. Sawaya, Catherine T. Chaton, Matthias Wilmanns, David Eisenberg, Annabel H. A. Parret, Konstantin V. Korotkov
Journal Of Molecular Biology, Nov 2018 DOI: 10.1016/j.jmb.2018.11.003
Journal Paper B21-High Throughput SAXS
Crystal structure of the apo-form of NADPH-dependent thioredoxin reductase from a methane-producing archaeon
Ruben M. Buey, Ruth A. Schmitz, Bob B. Buchanan, Monica Balsera
Antioxidants, 7 Nov 2018 DOI: 10.3390/antiox7110166
Journal Paper B21-High Throughput SAXS open access
Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities
Erik I. Hallin, Maria S. Eriksen, Sergei Baryshnikov, Oleksii Nikolaienko, Sverre Grødem, Tomohisa Hosokawa, Yasunori Hayashi, Clive R. Bramham, Petri Kursula
Journal Of Neurochemistry, 147 Nov 2018 DOI: 10.1111/jnc.14556
Journal Paper B21-High Throughput SAXS
The molecular basis of protein toxin HicA–dependent binding of the protein antitoxin HicB to DNA
Ashley J. Winter, Christopher Williams, Michail N. Isupov, Hannah Crocker, Mariya Gromova, Philip Marsh, Oliver J. Wilkinson, Mark S. Dillingham, Nicholas J. Harmer, Richard W. Titball, Matthew P. Crump
Journal Of Biological Chemistry, Oct 2018 DOI: 10.1074/jbc.RA118.005173
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens
Vivek Srinivas, Hugo Lebrette, Daniel Lundin, Yuri Kutin, Margareta Sahlin, Michael Lerche, Jürgen Eirich, Rui M. M. Branca, Nicholas Cox, Britt-Marie Sjöberg, Martin Högbom
Nature, 47 Oct 2018 DOI: 10.1038/s41586-018-0653-6
Journal Paper B21-High Throughput SAXS I24-Microfocus Macromolecular Crystallography
The X-ray structure of human calbindin-D28K: an improved model
James W. Noble, Rehab Almalki, S. Mark Roe, Armin Wagner, Ramona Duman, John Atack
Acta Crystallographica Section D Structural Biology, 74 Oct 2018 DOI: 10.1107/S2059798318011610
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I23-Long wavelength MX open access
It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate
Indu Santhanagopalan, Matteo T. Degiacomi, Dale A. Shepherd, Georg K. A. Hochberg, Justin L. P. Benesch, Elizabeth Vierling
Journal Of Biological Chemistry, Oct 2018 DOI: 10.1074/jbc.RA118.005421
Journal Paper B21-High Throughput SAXS open access
Conformation and aggregation of selectively pegylated and lipidated gastric peptide hormone human PYY 3-36
Valeria Castelletto, Ian W. Hamley, Jani Seitsonen, Janne Ruokolainen, Gemma Harris, Kathrin Bellmann-Sickert, Annette G. Beck-Sickinger
Biomacromolecules, Sept 2018 DOI: 10.1021/acs.biomac.8b01209
Journal Paper B21-High Throughput SAXS
High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1
Matti Myllykoski, Maria A. Eichel, Ramona B. Jung, Sørge Kelm, Hauke B. Werner, Petri Kursula
Journal Of Neurochemistry, Sept 2018 DOI: 10.1111/jnc.14598
Journal Paper B21-High Throughput SAXS
X-ray structure of full-length human RuvB-Like 2 – mechanistic insights into coupling between ATP binding and mechanical action
Sara Silva, Jose A. Brito, Rocío Arranz, Carlos Óscar S. Sorzano, Christine Ebel, James Doutch, Mark D. Tully, José-María Carazo, José L. Carrascosa, Pedro M. Matias, Tiago M. Bandeiras
Scientific Reports, 8 Sept 2018 DOI: 10.1038/s41598-018-31997-z
Journal Paper B21-High Throughput SAXS open access
Biocompatible single-chain polymer nanoparticles for drug delivery – a dual approach
A. Pia P. Kroger, Naomi M. Hamelmann, Alberto Juan, Saskia Lindhoud, Jos M. J. Paulusse
Acs Applied Materials & Interfaces, Aug 2018 DOI: 10.1021/acsami.8b07450
Journal Paper B21-High Throughput SAXS open access
Internal cleavage and synergy with twisted gastrulation enhance BMP inhibition by BMPER
Michael P. Lockhart-Cairns, Karen Tzia Wei Lim, Alexandra Zuk, Alan R. F. Godwin, Stuart A. Cain, Gerhard Sengle, Clair Baldock
Matrix Biology, Aug 2018 DOI: 10.1016/j.matbio.2018.08.006
Journal Paper B21-High Throughput SAXS open access
Bacillus subtilis HelD, an RNA polymerase interacting helicase, forms amyloid-like fibrils
Gundeep Kaur, Srajan Kapoor, Krishan G. Thakur
Frontiers In Microbiology, 9 Aug 2018 DOI: 10.3389/fmicb.2018.01934
Journal Paper B21-High Throughput SAXS open access
Structural analysis of human NHLRC2, mutations of which are associated with FINCA disease
Ekaterina Biterova, Alexander Ignatyev, Johanna Uusimaa, Reetta Hinttala, Lloyd W. Ruddock
Plos One, 13 Aug 2018 DOI: 10.1371/journal.pone.0202391
Journal Paper B21-High Throughput SAXS open access
Pectin conformation in solution
Katerina Alba, Richard J. Bingham, Patrick A. Gunning, Peter J. Wilde, V. Kontogiorgos
The Journal Of Physical Chemistry B, Jul 2018 DOI: 10.1021/acs.jpcb.8b04790
Journal Paper B21-High Throughput SAXS
Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils
Gundeep Kaur, Soni Kaundal, Srajan Kapoor, Jonathan M. Grimes, Juha T. Huiskonen, Krishan Gopal Thakur
Scientific Reports, 8 Jul 2018 DOI: 10.1038/s41598-018-28290-4
Journal Paper B21-High Throughput SAXS open access
Merging in-solution x-ray and neutron scattering data allows fine structural analysis of membrane–protein detergent complexes
Gaetan Dias Mirandela, Giulia Tamburrino, Miloš T. Ivanović, Felix M. Strnad, Olwyn Byron, Tim Rasmussen, Paul A. Hoskisson, Jochen S. Hub, Ulrich Zachariae, Frank Gabel, Arnaud Javelle
The Journal Of Physical Chemistry Letters, Jul 2018 DOI: 10.1021/acs.jpclett.8b01598
Journal Paper B21-High Throughput SAXS open access
Restructuring of lipid membranes by an arginine-capped peptide bolaamphiphile
Valeria Castelletto, Ruth H. Barnes, Kimon-Andreas Karatzas, Charlotte J. C. Edwards-Gayle, Francesca Greco, Ian W. Hamley, Jani Seitsonen, Janne Ruokolainen
Langmuir, Jul 2018 DOI: 10.1021/acs.langmuir.8b01014
Journal Paper B21-High Throughput SAXS
Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly
James M. Dunce, Orla M. Dunne, Matthew Ratcliff, Claudia Millán, Suzanne Madgwick, Isabel Uson, Owen R. Davies
Nature Structural & Molecular Biology, 7 June 2018 DOI: 10.1038/s41594-018-0078-9
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) open access
The structure of SALM5 suggests a dimeric assembly for the presynaptic RPTP ligand recognition
Sudeep Karki, Prodeep Paudel, Celeste Sele, Alexander V. Shkumatov, Tommi Kajander
Protein Engineering, Design And Selection, 44 June 2018 DOI: 10.1093/protein/gzy012
Journal Paper B21-High Throughput SAXS
Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition
D. Sean Froese, Jolanta Kopec, Elzbieta Rembeza, Gustavo Arruda Bezerra, Anselm Erich Oberholzer, Terttu Suormala, Seraina Lutz, Rod Chalk, Oktawia Borkowska, Matthias R. Baumgartner, Wyatt W. Yue
Nature Communications, 9 June 2018 DOI: 10.1038/s41467-018-04735-2
Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) open access
The effect of lipidation on the self-assembly of the gut derived peptide hormone PYY3-36
Jessica A. Hutchinson, Samuel Burholt, Ian W. Hamley, Anna-Karin Lundback, Shahid Uddin, Ana Lucia Gomes Dos Santos, Mehedi Reza, Jani Seitsonen, Janne Ruokolainen
Bioconjugate Chemistry, June 2018 DOI: 10.1021/acs.bioconjchem.8b00286
Journal Paper B21-High Throughput SAXS I22-Small angle scattering & Diffraction
Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge
Markus Meier, Aniel Moya-Torres, Natalie J. Krahn, Matthew D. Mcdougall, George L. Orriss, Ewan K. S. Mcrae, Evan P. Booy, Kevin Mceleney, Trushar R. Patel, Sean A. Mckenna, Jörg Stetefeld
Nucleic Acids Research, 34 May 2018 DOI: 10.1093/nar/gky307
Journal Paper B21-High Throughput SAXS open access
Arginine-containing surfactant-like peptides: Interaction with lipid membranes and antimicrobial activity
Valeria Castelletto, Ruth H. Barnes, Kimon-Andreas Karatzas, Charlotte J. C. Edwards-Gayle, Francesca Greco, Ian W. Hamley, Robert Rambo, Jani Seitsonen, Janne Ruokolainen
Biomacromolecules, May 2018 DOI: 10.1021/acs.biomac.8b00391
Journal Paper B21-High Throughput SAXS I22-Small angle scattering & Diffraction
Stability of local secondary structure determines selectivity of viral RNA chaperones
Jack P. K. Bravo, Alexander Borodavka, Anders Barth, Antonio N. Calabrese, Peter Mojzes, Joseph J. B. Cockburn, Don C. Lamb, Roman Tuma
Nucleic Acids Research, 190 May 2018 DOI: 10.1093/nar/gky394
Journal Paper B21-High Throughput SAXS open access
Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S
Beatriz Trastoy, Erik Klontz, Jared Orwenyo, Alberto Marina, Lai-Xi Wang, Eric J. Sundberg, Marcelo E. Guerin
Nature Communications, 9 May 2018 DOI: 10.1038/s41467-018-04300-x
Journal Paper B21-High Throughput SAXS open access
An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles
Stephen C. L. Hall, Cecilia Tognoloni, Jack Charlton, Eilis C. Bragginton, Alice J. Rothnie, Pooja Sridhar, Mark Wheatley, Timothy J. Knowles, Thomas Arnold, Karen J. Edler, Tim R. Dafforn
Nanoscale, May 2018 DOI: 10.1039/C8NR01322E
Journal Paper B21-High Throughput SAXS open access
Structural and functional characterisation of feline calicivirus entry
Michaela Jayne Conley
Apr 2018
Thesis B21-High Throughput SAXS
Structure of Radical-Induced Cell Death1 hub domain reveals a common αα-scaffold for disorder in transcriptional networks
Katrine Bugge, Lasse Staby, Katherine R. Kemplen, Charlotte O'Shea, Sidsel K. Bendsen, Mikael K. Jensen, Johan G. Olsen, Karen Skriver, Birthe B. Kragelund
Structure, Apr 2018 DOI: 10.1016/j.str.2018.03.013
Journal Paper B21-High Throughput SAXS
Oligonucleotide length dependent formation of virus-like particles
Stan J. Maassen, Mark Vincent De Ruiter, Saskia Lindhoud, Jeroen J. L. M. Cornelissen
Chemistry - A European Journal, Mar 2018 DOI: 10.1002/chem.201800285
Journal Paper B21-High Throughput SAXS
Structural and functional studies on CHFR autoubiquitination
Leanna Louise Smith
Mar 2018
Thesis B21-High Throughput SAXS
The conformation and aggregation of proline-rich surfactant-like peptides
Ian W. Hamley, Valeria Castelletto, Ashkan Dehsorkhi, Juan Torras, Carlos Aleman, Irina Portnaya, Dganit Danino
The Journal Of Physical Chemistry B, Feb 2018 DOI: 10.1021/acs.jpcb.7b11463
Journal Paper B21-High Throughput SAXS B23-Circular Dichroism
Conformational flexibility of proteins involved in ribosome biogenesis: investigations via Small Angle X-Ray Scattering (SAXS)
Dritan Siliqi, James Foadi, Marco Mazzorana, Davide Altamura, Alfonso Méndez-Godoy, Nuria Sánchez-Puig
Crystals, 8 Feb 2018 DOI: 10.3390/cryst8030109
Journal Paper B21-High Throughput SAXS I24-Microfocus Macromolecular Crystallography open access
Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions
Georg K. A. Hochberg, Dale A. Shepherd, Erik G. Marklund, Indu Santhanagoplan, Matteo T. Degiacomi, Arthur Laganowsky, Timothy M. Allison, Eman Basha, Michael T. Marty, Martin R. Galpin, Weston B. Struwe, Andrew J. Baldwin, Elizabeth Vierling, Justin L. P. Benesch
Science, 359 Feb 2018 DOI: 10.1126/science.aam7229
Journal Paper B21-High Throughput SAXS I04-Macromolecular Crystallography
A novel approach to increase the stability of liposomal containers via in prep coating by poly[n-(2-hydroxypropyl)methacrylamide] with covalently attached cholesterol groups
Olga V. Zaborova, Sergey K. Filippov, Petr Chytil, Lubomir Kováčik, Karel Ulbrich, Alexander A. Yaroslavov, Tomaš Etrych
Macromolecular Chemistry And Physics, 4 Jan 2018 DOI: 10.1002/macp.201700508
Journal Paper B21-High Throughput SAXS
Investigation into the mechanism of homo- and heterodimerization of angiotensin-converting enzyme
J. Albert Abrie, Wessel J. A. Moolman, Gyles E. Cozier, Sylva L. Schwager, K. Ravi Acharya, Edward D. Sturrock
Molecular Pharmacology, Jan 2018 DOI: 10.1124/mol.117.110866
Journal Paper B21-High Throughput SAXS open access
Structural characterization of nanoparticles formed by fluorinated poly(2-oxazoline)-based polyphiles
Anna Riabtseva, Leonid I. Kaberov, Laurence Noirez, Vasyl Ryukhtin, Corinne Nardin, Bart Veerbraeken, Richard Hoogenboom, Petr Stepanek, Sergey K. Filippov
European Polymer Journal, Jan 2018 DOI: 10.1016/j.eurpolymj.2018.01.007
Journal Paper B21-High Throughput SAXS
  1. Yovana Cabrera, Leire Dublang, José Angel Fernández-Higuero, David Albesa-Jove, Maria Lucas, Ana Rosa Viguera, Marcelo E. Guerin, Jose M. G. Vilar, Arturo Muga, Fernando Moro, "Regulation of human HSC70 ATPase and chaperone activities by Apg2: Role of the acidic subdomain", Journal Of Molecular Biology (2018), DOI: 10.1016/j.jmb.2018.11.026
  2. Ruben M. Buey, David Fernandez-Justel, Jose M. De Pereda, José L. Revuelta, Peter Schürmann, Bob B. Buchanan, Monica Balsera, "Ferredoxin-linked flavoenzyme defines a family of pyridine nucleotide-independent thioredoxin reductases", Proceedings Of The National Academy Of Sciences, 239 (2018), DOI: 10.1073/pnas.1812781115
  3. James M. Dunce, Amy E. Milburn, Manickam Gurusaran, Irene Da Cruz, Lee T. Sen, Ricardo Benavente, Owen R. Davies, "Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1", Nature Communications, 9 (2018), DOI: 10.1038/s41467-018-07794-7
  4. Neha Nirwan, Pratima Singh, Gyana Gourab Mishra, Christopher M. Johnson, Mark D. Szczelkun, Katsuaki Inoue, Kutti R. Vinothkumar, Kayarat Saikrishnan, "Hexameric assembly of the AAA+ protein McrB is necessary for GTPase activity", Nucleic Acids Research, 57 (2018), DOI: 10.1093/nar/gky1170
  5. Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D. R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras, "Interactome rewiring following pharmacological targeting of BET bromodomains", Molecular Cell (2018), DOI: 10.1016/j.molcel.2018.11.006
  6. Evandro Ares De Araújo, Mário De Oliveira Neto, Igor Polikarpov, "Biochemical characterization and low-resolution SAXS structure of two-domain endoglucanase BlCel9 from Bacillus licheniformis", Applied Microbiology And Biotechnology, 111 (2018), DOI: 10.1007/s00253-018-9508-1
  7. Matthew Leivers, John M. Seddon, Marc Declercq, Eric S. J. Robles, Paul Frederick Luckham, "Measurement of forces between supported cationic bilayers by colloid probe atomic force microscopy: electrolyte concentration and composition", Langmuir (2018), DOI: 10.1021/acs.langmuir.8b03555
  8. Abril Gijsbers, Diana Montagut, Alfonso Méndez-Godoy, Davide Altamura, Michele Saviano, Dritan Siliqi, Nuria Sánchez-Puig, "Interaction of the gtpase elongation factor Like-1 with the Shwachman-Diamond Syndrome protein and its missense mutations", International Journal Of Molecular Sciences, 19 (2018), DOI: 10.3390/ijms19124012
  9. Kousik Gayen, Kingshuk Basu, Dipayan Bairagi, Valeria Castelletto, Ian W. Hamley, Arindam Banerjee, "Amino-acid-based metallo-hydrogel that acts like an esterase", Acs Applied Bio Materials (2018), DOI: 10.1021/acsabm.8b00513
  10. Marta Compte, Seandean Lykke Harwood, Ines G. Munoz, Rocio Navarro, Manuela Zonca, Gema Perez-Chacon, Ainhoa Erce-Llamazares, Nekane Merino, Antonio Tapia-Galisteo, Angel M. Cuesta, Kasper Mikkelsen, Eduardo Caleiras, Natalia Nuñez-Prado, M. Angela Aznar, Simon Lykkemark, Jorge Martínez-Torrecuadrada, Ignacio Melero, Francisco J. Blanco, Jorge Bernardino De La Serna, Juan M. Zapata, Laura Sanz, Luis Alvarez-Vallina, "A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity", Nature Communications, 9 (2018), DOI: 10.1038/s41467-018-07195-w
  11. Anne T. Tuukkanen, Diana Freire, Sum Chan, Mark A. Arbing, Robert W. Reed, Timothy J. Evans, Grasilda Zenkeviciutė, Jennifer Kim, Sara Kahng, Michael R. Sawaya, Catherine T. Chaton, Matthias Wilmanns, David Eisenberg, Annabel H. A. Parret, Konstantin V. Korotkov, "Structural variability of EspG chaperones from mycobacterial ESX-1, ESX-3 and ESX-5 Type VII secretion systems", Journal Of Molecular Biology (2018), DOI: 10.1016/j.jmb.2018.11.003
  12. Ruben M. Buey, Ruth A. Schmitz, Bob B. Buchanan, Monica Balsera, "Crystal structure of the apo-form of NADPH-dependent thioredoxin reductase from a methane-producing archaeon", Antioxidants, 7 (2018), DOI: 10.3390/antiox7110166
  13. Erik I. Hallin, Maria S. Eriksen, Sergei Baryshnikov, Oleksii Nikolaienko, Sverre Grødem, Tomohisa Hosokawa, Yasunori Hayashi, Clive R. Bramham, Petri Kursula, "Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities", Journal Of Neurochemistry, 147, 323 - 343 (2018), DOI: 10.1111/jnc.14556
  14. Ashley J. Winter, Christopher Williams, Michail N. Isupov, Hannah Crocker, Mariya Gromova, Philip Marsh, Oliver J. Wilkinson, Mark S. Dillingham, Nicholas J. Harmer, Richard W. Titball, Matthew P. Crump, "The molecular basis of protein toxin HicA–dependent binding of the protein antitoxin HicB to DNA", Journal Of Biological Chemistry (2018), DOI: 10.1074/jbc.RA118.005173
  15. Vivek Srinivas, Hugo Lebrette, Daniel Lundin, Yuri Kutin, Margareta Sahlin, Michael Lerche, Jürgen Eirich, Rui M. M. Branca, Nicholas Cox, Britt-Marie Sjöberg, Martin Högbom, "Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens", Nature, 47 (2018), DOI: 10.1038/s41586-018-0653-6
  16. James W. Noble, Rehab Almalki, S. Mark Roe, Armin Wagner, Ramona Duman, John Atack, "The X-ray structure of human calbindin-D28K: an improved model", Acta Crystallographica Section D Structural Biology, 74, 1008 - 1014 (2018), DOI: 10.1107/S2059798318011610
  17. Indu Santhanagopalan, Matteo T. Degiacomi, Dale A. Shepherd, Georg K. A. Hochberg, Justin L. P. Benesch, Elizabeth Vierling, "It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate", Journal Of Biological Chemistry (2018), DOI: 10.1074/jbc.RA118.005421
  18. Valeria Castelletto, Ian W. Hamley, Jani Seitsonen, Janne Ruokolainen, Gemma Harris, Kathrin Bellmann-Sickert, Annette G. Beck-Sickinger, "Conformation and aggregation of selectively pegylated and lipidated gastric peptide hormone human PYY 3-36", Biomacromolecules (2018), DOI: 10.1021/acs.biomac.8b01209
  19. Matti Myllykoski, Maria A. Eichel, Ramona B. Jung, Sørge Kelm, Hauke B. Werner, Petri Kursula, "High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1", Journal Of Neurochemistry (2018), DOI: 10.1111/jnc.14598
  20. Sara Silva, Jose A. Brito, Rocío Arranz, Carlos Óscar S. Sorzano, Christine Ebel, James Doutch, Mark D. Tully, José-María Carazo, José L. Carrascosa, Pedro M. Matias, Tiago M. Bandeiras, "X-ray structure of full-length human RuvB-Like 2 – mechanistic insights into coupling between ATP binding and mechanical action", Scientific Reports, 8 (2018), DOI: 10.1038/s41598-018-31997-z
  21. A. Pia P. Kroger, Naomi M. Hamelmann, Alberto Juan, Saskia Lindhoud, Jos M. J. Paulusse, "Biocompatible single-chain polymer nanoparticles for drug delivery – a dual approach", Acs Applied Materials & Interfaces (2018), DOI: 10.1021/acsami.8b07450
  22. Michael P. Lockhart-Cairns, Karen Tzia Wei Lim, Alexandra Zuk, Alan R. F. Godwin, Stuart A. Cain, Gerhard Sengle, Clair Baldock, "Internal cleavage and synergy with twisted gastrulation enhance BMP inhibition by BMPER", Matrix Biology (2018), DOI: 10.1016/j.matbio.2018.08.006
  23. Gundeep Kaur, Srajan Kapoor, Krishan G. Thakur, "Bacillus subtilis HelD, an RNA polymerase interacting helicase, forms amyloid-like fibrils", Frontiers In Microbiology, 9 (2018), DOI: 10.3389/fmicb.2018.01934
  24. Ekaterina Biterova, Alexander Ignatyev, Johanna Uusimaa, Reetta Hinttala, Lloyd W. Ruddock, "Structural analysis of human NHLRC2, mutations of which are associated with FINCA disease", Plos One, 13 (2018), DOI: 10.1371/journal.pone.0202391
  25. Katerina Alba, Richard J. Bingham, Patrick A. Gunning, Peter J. Wilde, V. Kontogiorgos, "Pectin conformation in solution", The Journal Of Physical Chemistry B (2018), DOI: 10.1021/acs.jpcb.8b04790
  26. Gundeep Kaur, Soni Kaundal, Srajan Kapoor, Jonathan M. Grimes, Juha T. Huiskonen, Krishan Gopal Thakur, "Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils", Scientific Reports, 8 (2018), DOI: 10.1038/s41598-018-28290-4
  27. Gaetan Dias Mirandela, Giulia Tamburrino, Miloš T. Ivanović, Felix M. Strnad, Olwyn Byron, Tim Rasmussen, Paul A. Hoskisson, Jochen S. Hub, Ulrich Zachariae, Frank Gabel, Arnaud Javelle, "Merging in-solution x-ray and neutron scattering data allows fine structural analysis of membrane–protein detergent complexes", The Journal Of Physical Chemistry Letters (2018), DOI: 10.1021/acs.jpclett.8b01598
  28. Valeria Castelletto, Ruth H. Barnes, Kimon-Andreas Karatzas, Charlotte J. C. Edwards-Gayle, Francesca Greco, Ian W. Hamley, Jani Seitsonen, Janne Ruokolainen, "Restructuring of lipid membranes by an arginine-capped peptide bolaamphiphile", Langmuir (2018), DOI: 10.1021/acs.langmuir.8b01014
  29. James M. Dunce, Orla M. Dunne, Matthew Ratcliff, Claudia Millán, Suzanne Madgwick, Isabel Uson, Owen R. Davies, "Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly", Nature Structural & Molecular Biology, 7 (2018), DOI: 10.1038/s41594-018-0078-9
  30. Sudeep Karki, Prodeep Paudel, Celeste Sele, Alexander V. Shkumatov, Tommi Kajander, "The structure of SALM5 suggests a dimeric assembly for the presynaptic RPTP ligand recognition", Protein Engineering, Design And Selection, 44 (2018), DOI: 10.1093/protein/gzy012
  31. D. Sean Froese, Jolanta Kopec, Elzbieta Rembeza, Gustavo Arruda Bezerra, Anselm Erich Oberholzer, Terttu Suormala, Seraina Lutz, Rod Chalk, Oktawia Borkowska, Matthias R. Baumgartner, Wyatt W. Yue, "Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition", Nature Communications, 9 (2018), DOI: 10.1038/s41467-018-04735-2
  32. Jessica A. Hutchinson, Samuel Burholt, Ian W. Hamley, Anna-Karin Lundback, Shahid Uddin, Ana Lucia Gomes Dos Santos, Mehedi Reza, Jani Seitsonen, Janne Ruokolainen, "The effect of lipidation on the self-assembly of the gut derived peptide hormone PYY3-36", Bioconjugate Chemistry (2018), DOI: 10.1021/acs.bioconjchem.8b00286
  33. Markus Meier, Aniel Moya-Torres, Natalie J. Krahn, Matthew D. Mcdougall, George L. Orriss, Ewan K. S. Mcrae, Evan P. Booy, Kevin Mceleney, Trushar R. Patel, Sean A. Mckenna, Jörg Stetefeld, "Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge", Nucleic Acids Research, 34 (2018), DOI: 10.1093/nar/gky307
  34. Valeria Castelletto, Ruth H. Barnes, Kimon-Andreas Karatzas, Charlotte J. C. Edwards-Gayle, Francesca Greco, Ian W. Hamley, Robert Rambo, Jani Seitsonen, Janne Ruokolainen, "Arginine-containing surfactant-like peptides: Interaction with lipid membranes and antimicrobial activity", Biomacromolecules (2018), DOI: 10.1021/acs.biomac.8b00391
  35. Jack P. K. Bravo, Alexander Borodavka, Anders Barth, Antonio N. Calabrese, Peter Mojzes, Joseph J. B. Cockburn, Don C. Lamb, Roman Tuma, "Stability of local secondary structure determines selectivity of viral RNA chaperones", Nucleic Acids Research, 190 (2018), DOI: 10.1093/nar/gky394
  36. Beatriz Trastoy, Erik Klontz, Jared Orwenyo, Alberto Marina, Lai-Xi Wang, Eric J. Sundberg, Marcelo E. Guerin, "Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S", Nature Communications, 9 (2018), DOI: 10.1038/s41467-018-04300-x
  37. Stephen C. L. Hall, Cecilia Tognoloni, Jack Charlton, Eilis C. Bragginton, Alice J. Rothnie, Pooja Sridhar, Mark Wheatley, Timothy J. Knowles, Thomas Arnold, Karen J. Edler, Tim R. Dafforn, "An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles", Nanoscale (2018), DOI: 10.1039/C8NR01322E
  38. [Thesis] Michaela Jayne Conley, "Structural and functional characterisation of feline calicivirus entry" (2018)
  39. Katrine Bugge, Lasse Staby, Katherine R. Kemplen, Charlotte O'Shea, Sidsel K. Bendsen, Mikael K. Jensen, Johan G. Olsen, Karen Skriver, Birthe B. Kragelund, "Structure of Radical-Induced Cell Death1 hub domain reveals a common αα-scaffold for disorder in transcriptional networks", Structure (2018), DOI: 10.1016/j.str.2018.03.013
  40. Stan J. Maassen, Mark Vincent De Ruiter, Saskia Lindhoud, Jeroen J. L. M. Cornelissen, "Oligonucleotide length dependent formation of virus-like particles", Chemistry - A European Journal (2018), DOI: 10.1002/chem.201800285
  41. [Thesis] Leanna Louise Smith, "Structural and functional studies on CHFR autoubiquitination" (2018)
  42. Ian W. Hamley, Valeria Castelletto, Ashkan Dehsorkhi, Juan Torras, Carlos Aleman, Irina Portnaya, Dganit Danino, "The conformation and aggregation of proline-rich surfactant-like peptides", The Journal Of Physical Chemistry B (2018), DOI: 10.1021/acs.jpcb.7b11463
  43. Dritan Siliqi, James Foadi, Marco Mazzorana, Davide Altamura, Alfonso Méndez-Godoy, Nuria Sánchez-Puig, "Conformational flexibility of proteins involved in ribosome biogenesis: investigations via Small Angle X-Ray Scattering (SAXS)", Crystals, 8 (2018), DOI: 10.3390/cryst8030109
  44. Georg K. A. Hochberg, Dale A. Shepherd, Erik G. Marklund, Indu Santhanagoplan, Matteo T. Degiacomi, Arthur Laganowsky, Timothy M. Allison, Eman Basha, Michael T. Marty, Martin R. Galpin, Weston B. Struwe, Andrew J. Baldwin, Elizabeth Vierling, Justin L. P. Benesch, "Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions", Science, 359, 930 - 935 (2018), DOI: 10.1126/science.aam7229
  45. Olga V. Zaborova, Sergey K. Filippov, Petr Chytil, Lubomir Kováčik, Karel Ulbrich, Alexander A. Yaroslavov, Tomaš Etrych, "A novel approach to increase the stability of liposomal containers via in prep coating by poly[n-(2-hydroxypropyl)methacrylamide] with covalently attached cholesterol groups", Macromolecular Chemistry And Physics, 4 (2018), DOI: 10.1002/macp.201700508
  46. J. Albert Abrie, Wessel J. A. Moolman, Gyles E. Cozier, Sylva L. Schwager, K. Ravi Acharya, Edward D. Sturrock, "Investigation into the mechanism of homo- and heterodimerization of angiotensin-converting enzyme", Molecular Pharmacology (2018), DOI: 10.1124/mol.117.110866
  47. Anna Riabtseva, Leonid I. Kaberov, Laurence Noirez, Vasyl Ryukhtin, Corinne Nardin, Bart Veerbraeken, Richard Hoogenboom, Petr Stepanek, Sergey K. Filippov, "Structural characterization of nanoparticles formed by fluorinated poly(2-oxazoline)-based polyphiles", European Polymer Journal (2018), DOI: 10.1016/j.eurpolymj.2018.01.007
  • Contact Us
  • About Diamond Light Source
  • Procurement
  • Supply Chain Transparency
  • Cookie Policy
  • Website Terms of Use
  • Privacy Notice

Diamond Light Source

Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.

Follow us on Facebook Follow us on Linkedin Follow us on Instagram Follow us on Bluesky

Diamond Light Source Ltd
Diamond House
Harwell Science & Innovation Campus
Didcot
Oxfordshire
OX11 0DE

See on Google Maps

Copyright © Diamond Light Source. Diamond Light Source® and the Diamond logo are registered trademarks of Diamond Light Source Ltd

Registered in England and Wales at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom. Company number: 4375679. VAT number: 287 461 957. Economic Operators Registration and Identification (EORI) number: GB287461957003.

feedback