Instruments by Science Group
Macromolecular
Soft Condensed 
Imaging and
Biological
Magnetic
Structures and
Crystallography 
Spectroscopy B21 Contact
Beamline phone numbers:
+44 (0) 1235 77 8627
+44 (0) 1235 77 8640
Principal Beamline Scientist:
Nathan Cowieson
Tel: +44 (0) 1235 567 504
E-mail: [email protected]
Science Group Leader
Robert Rambo
Email: [email protected]
Tel: +44 (0)1235 56 7675
B21 High Throughput SAXS
Status: Operational
Beamsize: <75 μm
Detector: Eiger 4M
Energy: 6 - 23 keV
Detector: Eiger 4M
Energy: 6 - 23 keV
62 items found for 2022 [total: 654]
A solution structure analysis reveals a bent collagen triple helix in the complement activation recognition molecule mannan-binding lectin Journal Of Biological Chemistry, 174 Dec 2022 DOI: 10.1016/j.jbc.2022.102799
The crystal structure of the EspB-EspK virulence factor-chaperone complex suggests an additional type VII secretion mechanism in M. tuberculosis Journal Of Biological Chemistry, 113 Dec 2022 DOI: 10.1016/j.jbc.2022.102761
Self-assembly of tunable intrinsically disordered peptide amphiphiles Biomacromolecules, Dec 2022 DOI: 10.1021/acs.biomac.2c00866
A novel factor-dependent internal ribosome entry site and programmed frameshifting signal in the bemisia-associated dicistrovirus 2 Dec 2022
Thesis B21-High Throughput SAXS
Ex vivo evaluation of ethosomes and transethosomes applied on human skin: a comparative study International Journal Of Molecular Sciences, 23 Dec 2022 DOI: 10.3390/ijms232315112
Micelle and nanotape formation of benzene tricarboxamide analogues with selective cancer cell cytotoxicity Acs Omega, 49 Dec 2022 DOI: 10.1021/acsomega.2c05940
Structural insights into p300 regulation and acetylation-dependent genome organisation Nature Communications, 13 Dec 2022 DOI: 10.1038/s41467-022-35375-2
Influence of polymer molar mass and mixture stoichiometry on polyelectrolyte complexes of poly(l-arginine) and Poly(l-glutamic acid) Polymer, 3 Nov 2022 DOI: 10.1016/j.polymer.2022.125497
Structural insights into the contactin 1 - neurofascin 155 adhesion complex Nature Communications, 13 Nov 2022 DOI: 10.1038/s41467-022-34302-9
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Relations between structure and Zn(II) binding affinity shed light on the mechanisms of Rad50 hook domain functioning and its phosphorylation International Journal Of Molecular Sciences, 23 Oct 2022 DOI: 10.3390/ijms231911140
A study of the complex relationship between self-assembly, activity and material properties of low molecular weight gelators Oct 2022 DOI: 10.5525/gla.thesis.83209
Thesis B21-High Throughput SAXS
CD44 and CD221 directed magnetic cubosomes for the targeted delivery of helenalin to rhabdomyosarcoma cells Nano Research, 12 Oct 2022 DOI: 10.1007/s12274-022-5037-4
Investigations of prokaryotic defense systems Oct 2022
Thesis B21-High Throughput SAXS
Deciphering the alphabet of disorder - Glu and Asp act differently on local but not global properties Biomolecules, 12 Oct 2022 DOI: 10.3390/biom12101426
Light-responsive molecular release from cubosomes using swell-squeeze lattice control Journal Of The American Chemical Society, 2014 Oct 2022 DOI: 10.1021/jacs.2c08583
Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly Nature Communications, 13 Oct 2022 DOI: 10.1038/s41467-022-34058-2
Structural model of a Porphyromonas gingivalis type IX secretion system shuttle complex Journal Of Molecular Biology, 7 Oct 2022 DOI: 10.1016/j.jmb.2022.167871
Light responsiveness and assembly of arylazopyrazole-based surfactants in neat and mixed CTAB micelles Jacs Au, Oct 2022 DOI: 10.1021/jacsau.2c00453
Structural-functional relationship of the ribonucleolytic activity of aIF5A from Sulfolobus solfataricus Biomolecules, 12 Oct 2022 DOI: 10.3390/biom12101432
Non-canonical Staphylococcus aureus pathogenicity island repression Nucleic Acids Research, 2 Oct 2022 DOI: 10.1093/nar/gkac855
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) open access
The impact of forced degradation conditions on mAb dimer formation and subsequent influence on aggregation propensity Mabs, 14 Oct 2022 DOI: 10.1080/19420862.2022.2127172
Flavour compounds can bind to proteins and affect their structure Oct 2022
Science Highlight B21-High Throughput SAXS
Flavour compounds affect protein structure: The effect of methyl anthranilate on bovine serum albumin conformation Food Chemistry, 388 Sept 2022 DOI: 10.1016/j.foodchem.2022.133013
Journal Paper B21-High Throughput SAXS
Fine-tuning of the Hsc70-based human protein disaggregase machinery by the distinctive C-terminal extension of Apg2 Journal Of Molecular Biology, 47 Sept 2022 DOI: 10.1016/j.jmb.2022.167841
Amino acid containing amphiphilic hydrogelators with antibacterial and antiparasitic activities Soft Matter, 18 Sept 2022 DOI: 10.1039/D2SM00562J
Journal Paper B21-High Throughput SAXS
Heparins mediate the multimer assembly of secreted Noggin Protein Science, 31 Sept 2022 DOI: 10.1002/pro.4419
Journal Paper B21-High Throughput SAXS
Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1) Scientific Reports, 12 Sept 2022 DOI: 10.1038/s41598-022-18795-4
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography I03-Macromolecular Crystallography open access
Coiled-coil structure of meiosis protein TEX12 and conformational regulation by its C-terminal tip Communications Biology, 5 Sept 2022 DOI: 10.1038/s42003-022-03886-9
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Interaction between glyphosate pesticide and amphiphilic peptides for colorimetric analysis Nanoscale Advances, 147 Aug 2022 DOI: 10.1039/D2NA00345G
Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse Nature Communications, 13 Aug 2022 DOI: 10.1038/s41467-022-32577-6
Purification and characterization of inorganic pyrophosphatase for in vitro RNA transcription Biochemistry And Cell Biology, 7 Aug 2022 DOI: 10.1139/bcb-2022-0118
Structure-activity relationship of the dimeric and oligomeric forms of a cytotoxic biotherapeutic based on diphtheria toxin Biomolecules, 12 Aug 2022 DOI: 10.3390/biom12081111
Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti Nature Communications, 13 Aug 2022 DOI: 10.1038/s41467-022-32690-6
Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor Nature Communications, 13 Aug 2022 DOI: 10.1038/s41467-022-32728-9
Exploring Calbindin-IMPase fusion proteins structure and activity Biochemistry And Biophysics Reports, 30 Jul 2022 DOI: 10.1016/j.bbrep.2022.101266
Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch Proceedings Of The National Academy Of Sciences, 119 Jul 2022 DOI: 10.1073/pnas.2202209119
3D-printed SAXS chamber for controlled in situ dialysis and optical characterization Journal Of Synchrotron Radiation, 29 Jul 2022 DOI: 10.1107/S1600577522005136
Investigation of the function of the SH3-like domain of the Saccharopolyspora erythraea iron-dependent regulator Jul 2022
Thesis B21-High Throughput SAXS
Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes Cell Reports, 39 June 2022 DOI: 10.1016/j.celrep.2022.110959
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Minimalistic ice recrystallisation inhibitors based on phenylalanine Chemical Communications, June 2022 DOI: 10.1039/D2CC02531K
Non-ionic detergent assists formation of supercharged nanodiscs and insertion of membrane proteins Biochimica Et Biophysica Acta (bba) - Biomembranes, 1864 June 2022 DOI: 10.1016/j.bbamem.2022.183884
Structure and mechanism of two type III CRISPR defence nucleases activated by cyclic oligoadenylate June 2022
Thesis B21-High Throughput SAXS open access
Long acting injectables for therapeutic proteins Colloids And Surfaces B: Biointerfaces, 8 June 2022 DOI: 10.1016/j.colsurfb.2022.112644
Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E Journal Of Structural Biology, 12 June 2022 DOI: 10.1016/j.jsb.2022.107876
Biophysical characterisation of human LincRNA-p21 sense and antisense Alu inverted repeats Nucleic Acids Research, 50 June 2022 DOI: 10.1093/nar/gkac414
Diversity of mechanisms to control bacterial GTP homeostasis by the mutually exclusive binding of adenine and guanine nucleotides to IMP dehydrogenase Protein Science, 31 May 2022 DOI: 10.1002/pro.4314
Structural characterization of the full-length anti-CD20 antibody rituximab Frontiers In Molecular Biosciences, 9 Apr 2022 DOI: 10.3389/fmolb.2022.823174
Superstoichiometric binding of the anticancer agent titanocene dichloride by human serum transferrin and the accompanying lobe closure Biochemistry, 271 Apr 2022 DOI: 10.1021/acs.biochem.1c00813
Journal Paper B21-High Throughput SAXS
Global structure of the intrinsically disordered protein tau emerges from its local structure Jacs Au, Mar 2022 DOI: 10.1021/jacsau.1c00536
Targeting Xist with compounds that disrupt RNA structure and X inactivation Nature, Mar 2022 DOI: 10.1038/s41586-022-04537-z
Journal Paper B21-High Throughput SAXS
Mechanism of cooperative N-glycan processing by the multi-modular endoglycosidase EndoE Nature Communications, 13 Mar 2022 DOI: 10.1038/s41467-022-28722-w
Transparent colloidal crystals with structural colours Frontiers In Physics, 10 Mar 2022 DOI: 10.3389/fphy.2022.847142
Structural and biochemical characterisation of the prenylated flavin mononucleotide-dependent indole-3-carboxylic acid decarboxylase Journal Of Biological Chemistry, 632 Feb 2022 DOI: 10.1016/j.jbc.2022.101771
Structure and function of an atypical homodimeric actin capping protein from the malaria parasite Cellular And Molecular Life Sciences, 79 Feb 2022 DOI: 10.1007/s00018-021-04032-0
Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) open access
Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation Npj Biofilms And Microbiomes, 8 Feb 2022 DOI: 10.1038/s41522-022-00272-5
The role of lipid chains as determinants of membrane stability in the presence of styrene Langmuir, Jan 2022 DOI: 10.1021/acs.langmuir.1c02332
Conformational trapping of an ABC transporter in polymer lipid nanoparticles Biochemical Journal, 479 Jan 2022 DOI: 10.1042/BCJ20210312
MDGA1 negatively regulates amyloid precursor protein–mediated synapse inhibition in the hippocampus Proceedings Of The National Academy Of Sciences, 119 Jan 2022 DOI: 10.1073/pnas.2115326119
Journal Paper B21-High Throughput SAXS
Teneurin4 dimer structures reveal a calcium‐stabilized compact conformation supporting homomeric trans‐interactions The Embo Journal, 66 Jan 2022 DOI: 10.15252/embj.2020107505
Amyloid and hydrogel formation of a peptide sequence from a coronavirus spike protein Acs Nano, 1777 Jan 2022 DOI: 10.1021/acsnano.1c10658
Reconstitution of the DTX3L-PARP9 complex reveals determinants for high affinity heterodimerization and multimeric assembly Biochemical Journal, Jan 2022 DOI: 10.1042/BCJ20210722
The C-terminal domains of the PB2 subunit of the influenza A virus RNA polymerase directly interact with cellular GTPase Rab11a Journal Of Virology, Jan 2022 DOI: 10.1128/jvi.01979-21
- Hina Iqbal, Ka Wai Fung, Jayesh Gor, Anthony C. Bishop, George I. Makhatadze, Barbara Brodsky, Stephen J. Perkins, "A solution structure analysis reveals a bent collagen triple helix in the complement activation recognition molecule mannan-binding lectin", Journal Of Biological Chemistry, 174 (2022), DOI: 10.1016/j.jbc.2022.102799
- Abril Gijsbers, Mathias Eymery, Ye Gao, Isabella Menart, Vanesa Vinciauskaite, Dritan Siliqi, Peter J. Peters, Andrew Mccarthy, Raimond B. G. Ravelli, "The crystal structure of the EspB-EspK virulence factor-chaperone complex suggests an additional type VII secretion mechanism in M. tuberculosis", Journal Of Biological Chemistry, 113 (2022), DOI: 10.1016/j.jbc.2022.102761
- Tamara Ehm, Hila Shinar, Guy Jacoby, Sagi Meir, Gil Koren, Merav Segal Asher, Joanna Korpanty, Matthew P. Thompson, Nathan C. Gianneschi, Michael M. Kozlov, Salome Azoulay-Ginsburg, Roey J. Amir, Joachim O. Rädler, Roy Beck, "Self-assembly of tunable intrinsically disordered peptide amphiphiles", Biomacromolecules (2022), DOI: 10.1021/acs.biomac.2c00866
- [Thesis] Yihang Chen, "A novel factor-dependent internal ribosome entry site and programmed frameshifting signal in the bemisia-associated dicistrovirus 2" (2022)
- Elisabetta Esposito, Laura Calderan, Andrea Galvan, Enrica Cappellozza, Markus Drechsler, Paolo Mariani, Alessia Pepe, Maddalena Sguizzato, Enrico Vigato, Edoardo Dalla Pozza, Manuela Malatesta, "Ex vivo evaluation of ethosomes and transethosomes applied on human skin: a comparative study", International Journal Of Molecular Sciences, 23 (2022), DOI: 10.3390/ijms232315112
- Nada Aljuaid, Jani Seitsonen, Janne Ruokolainen, Francesca Greco, Ian W. Hamley, "Micelle and nanotape formation of benzene tricarboxamide analogues with selective cancer cell cytotoxicity", Acs Omega, 49 (2022), DOI: 10.1021/acsomega.2c05940
- Ziad Ibrahim, Tao Wang, Olivier Destaing, Nicola Salvi, Naghmeh Hoghoughi, Clovis Chabert, Alexandra Rusu, Jinjun Gao, Leonardo Feletto, Nicolas Reynoird, Thomas Schalch, Yingming Zhao, Martin Blackledge, Saadi Khochbin, Daniel Panne, "Structural insights into p300 regulation and acetylation-dependent genome organisation", Nature Communications, 13 (2022), DOI: 10.1038/s41467-022-35375-2
- Valeria Castelletto, Lucas De Mello, Foteini Arfara, Hermis Iatrou, Jani Seitsonen, Ian W. Hamley, "Influence of polymer molar mass and mixture stoichiometry on polyelectrolyte complexes of poly(l-arginine) and Poly(l-glutamic acid)", Polymer, 3 (2022), DOI: 10.1016/j.polymer.2022.125497
- Lucas M. P. Chataigner, Christos Gogou, Maurits A. Den Boer, Cátia P. Frias, Dominique M. E. Thies-Weesie, Joke C. M. Granneman, Albert J. R. Heck, Dimphna H. Meijer, Bert J. C. Janssen, "Structural insights into the contactin 1 - neurofascin 155 adhesion complex", Nature Communications, 13 (2022), DOI: 10.1038/s41467-022-34302-9
- Jozef Ba Tran, Michal Padjasek, Artur Krezel, "Relations between structure and Zn(II) binding affinity shed light on the mechanisms of Rad50 hook domain functioning and its phosphorylation", International Journal Of Molecular Sciences, 23 (2022), DOI: 10.3390/ijms231911140
- [Thesis] Daniel Mcdowall, "A study of the complex relationship between self-assembly, activity and material properties of low molecular weight gelators" (2022), DOI: 10.5525/gla.thesis.83209
- Hakmin Mun, Yuriy Chaban, Tanveer A. Tabish, Nanasaheb Thorat, Nathan Cowieson, C. David Owen, Helen E. Townley, "CD44 and CD221 directed magnetic cubosomes for the targeted delivery of helenalin to rhabdomyosarcoma cells", Nano Research, 12 (2022), DOI: 10.1007/s12274-022-5037-4
- [Thesis] Hannah Domgaard, "Investigations of prokaryotic defense systems" (2022)
- Mette Ahrensback Roesgaard, Jeppe E. Lundsgaard, Estella A. Newcombe, Nina L. Jacobsen, Francesco Pesce, Emil E. Tranchant, Søren Lindemose, Andreas Prestel, Rasmus Hartmann-Petersen, Kresten Lindorff-Larsen, Birthe B. Kragelund, "Deciphering the alphabet of disorder - Glu and Asp act differently on local but not global properties", Biomolecules, 12 (2022), DOI: 10.3390/biom12101426
- Beatrice E. Jones, Elaine A. Kelly, Nathan Cowieson, Giorgio Divitini, Rachel C. Evans, "Light-responsive molecular release from cubosomes using swell-squeeze lattice control", Journal Of The American Chemical Society, 2014 (2022), DOI: 10.1021/jacs.2c08583
- Elyse S. Fischer, Conny W. H. Yu, Johannes F. Hevler, Stephen H. Mclaughlin, Sarah L. Maslen, Albert J. R. Heck, Stefan M. V. Freund, David Barford, "Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly", Nature Communications, 13 (2022), DOI: 10.1038/s41467-022-34058-2
- Ben Dorgan, Yichao Liu, Sunjun Wang, Joseph Aduse-Opoku, Sara B. M. Whittaker, Mark A. J. Roberts, Christian D. Lorenz, Mike A. Curtis, James A. Garnett, "Structural model of a Porphyromonas gingivalis type IX secretion system shuttle complex", Journal Of Molecular Biology, 7 (2022), DOI: 10.1016/j.jmb.2022.167871
- Gunjan Tyagi, Jake L. Greenfield, Beatrice E. Jones, William N. Sharratt, Kasim Khan, Dale Seddon, Lorna A. Malone, Nathan Cowieson, Rachel C. Evans, Matthew J. Fuchter, Joao T. Cabral, "Light responsiveness and assembly of arylazopyrazole-based surfactants in neat and mixed CTAB micelles", Jacs Au (2022), DOI: 10.1021/jacsau.2c00453
- Alice Romagnoli, Paolo Moretti, Mattia D'Agostino, Jesmina Rexha, Nunzio Perta, Astra Piccinini, Daniele Di Marino, Francesco Spinozzi, Anna La Teana, "Structural-functional relationship of the ribonucleolytic activity of aIF5A from Sulfolobus solfataricus", Biomolecules, 12 (2022), DOI: 10.3390/biom12101432
- Laura Miguel-Romero, Mohammed Alqasmi, Julio Bacarizo, Jason A. Tan, Richard J. Cogdell, John Chen, Olwyn Byron, Gail E. Christie, Alberto Marina, José R. Penadés, "Non-canonical Staphylococcus aureus pathogenicity island repression", Nucleic Acids Research, 2 (2022), DOI: 10.1093/nar/gkac855
- Michael J. Knight, Léontine Floret, Nisha Patel, John O’hara, Elizabeth Rodriguez, "The impact of forced degradation conditions on mAb dimer formation and subsequent influence on aggregation propensity", Mabs, 14 (2022), DOI: 10.1080/19420862.2022.2127172
- [Science Highlight] Diamond Light Source, "Flavour compounds can bind to proteins and affect their structure" (2022)
- Vlad Dinu, Pallab Kumar Borah, Molly Muleya, David J Scott, Ryan Lithgo, Jacob Pattem, Stephen E. Harding, Gleb E. Yakubov, Ian D. Fisk, "Flavour compounds affect protein structure: The effect of methyl anthranilate on bovine serum albumin conformation", Food Chemistry, 388 (2022), DOI: 10.1016/j.foodchem.2022.133013
- Yovana Cabrera, Ganeko Bernardo-Seisdedos, Leire Dublang, David Albesa-Jove, Natalia Orozco, Ana Rosa Viguera, Oscar Millet, Arturo Muga, Fernando Moro, "Fine-tuning of the Hsc70-based human protein disaggregase machinery by the distinctive C-terminal extension of Apg2", Journal Of Molecular Biology, 47 (2022), DOI: 10.1016/j.jmb.2022.167841
- Biplab Mondal, Vivek Kumar Gupta, Biswanath Hansda, Arpita Bhoumik, Tanushree Mondal, Hemanta K. Majumder, Charlotte J. C. Edwards-Gayle, Ian W. Hamley, Parasuraman Jaisankar, Arindam Banerjee, "Amino acid containing amphiphilic hydrogelators with antibacterial and antiparasitic activities", Soft Matter, 18, 7201 - 7216 (2022), DOI: 10.1039/D2SM00562J
- Fabian Heide, Scott Legare, Vu To, Monika Gupta, Haben Gabir, Thomas Imhof, Aniel Moya-Torres, Matthew Mcdougall, Markus Meier, Manuel Koch, Jörg Stetefeld, "Heparins mediate the multimer assembly of secreted Noggin", Protein Science, 31 (2022), DOI: 10.1002/pro.4419
- Urvashi Sharma, Sandrine Vadon-Le Goff, Karl Harlos, Yuguang Zhao, Natacha Mariano, Cecile Bijakowski, Jean-Marie Bourhis, Catherine Moali, David J. S. Hulmes, Nushin Aghajari, "Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1)", Scientific Reports, 12 (2022), DOI: 10.1038/s41598-022-18795-4
- James M. Dunce, Lucy J. Salmon, Owen R. Davies, "Coiled-coil structure of meiosis protein TEX12 and conformational regulation by its C-terminal tip", Communications Biology, 5 (2022), DOI: 10.1038/s42003-022-03886-9
- Barbara B. Gerbelli, Pedro L. O. Filho, Bruna Cortez, Pedro T. Sodré, Mauricio D. Coutinho-Neto, Ian W. Hamley, Jani Seitsonen, Wendel A. Alves, "Interaction between glyphosate pesticide and amphiphilic peptides for colorimetric analysis", Nanoscale Advances, 147 (2022), DOI: 10.1039/D2NA00345G
- Jan Bláha, Tereza Skálová, Barbora Kalousková, Ondřej Skořepa, Denis Cmunt, Valéria Grobárová, Samuel Pazicky, Edita Poláchová, Celeste Abreu, Jan Stransky, Tomas Koval, Jarmila Duskova, Yuguang Zhao, Karl Harlos, Jindřich Hašek, Jan Dohnalek, Ondřej Vaněk, "Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse", Nature Communications, 13 (2022), DOI: 10.1038/s41467-022-32577-6
- Scott Tersteeg, Tyler Mrozowich, Amy Henrickson, Borries Demeler, Trushar R. Patel, "Purification and characterization of inorganic pyrophosphatase for in vitro RNA transcription", Biochemistry And Cell Biology, 7 (2022), DOI: 10.1139/bcb-2022-0118
- Marcin Mielecki, Marcin Ziemniak, Magdalena Ozga, Radosław Borowski, Jarosław Antosik, Angelika Kaczyńska, Beata Pająk, "Structure-activity relationship of the dimeric and oligomeric forms of a cytotoxic biotherapeutic based on diphtheria toxin", Biomolecules, 12 (2022), DOI: 10.3390/biom12081111
- Yoann Saucereau, Thomas H. Wilson, Matthew C. K. Tang, Martin C. Moncrieffe, Steven W. Hardwick, Dimitri Y. Chirgadze, Sandro G. Soares, Maria Jose Marcaida, Nicholas J. Gay, Monique Gangloff, "Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti", Nature Communications, 13 (2022), DOI: 10.1038/s41467-022-32690-6
- Olivia J. S. Macleod, Alexander D. Cook, Helena Webb, Mandy Crow, Roisin Burns, Maria Redpath, Stefanie Seisenberger, Camilla E. Trevor, Lori Peacock, Angela Schwede, Nicola Kimblin, Amanda F. Francisco, Julia Pepperl, Steve Rust, Paul Voorheis, Wendy Gibson, Martin C. Taylor, Matthew K. Higgins, Mark Carrington, "Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor", Nature Communications, 13 (2022), DOI: 10.1038/s41467-022-32728-9
- James Noble, John R. Atack, "Exploring Calbindin-IMPase fusion proteins structure and activity", Biochemistry And Biophysics Reports, 30 (2022), DOI: 10.1016/j.bbrep.2022.101266
- Maryline Fresquet, Michael P. Lockhart-Cairns, Samuel J. Rhoden, Thomas A. Jowitt, David C. Briggs, Clair Baldock, Paul E. Brenchley, Rachel Lennon, "Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch", Proceedings Of The National Academy Of Sciences, 119 (2022), DOI: 10.1073/pnas.2202209119
- Tamara Ehm, Julian Philipp, Martin Barkey, Martina Ober, Achim Theo Brinkop, David Simml, Miriam Von Westphalen, Bert Nickel, Roy Beck, Joachim O. Rädler, "3D-printed SAXS chamber for controlled in situ dialysis and optical characterization", Journal Of Synchrotron Radiation, 29 (2022), DOI: 10.1107/S1600577522005136
- [Thesis] Carita Hammar, "Investigation of the function of the SH3-like domain of the Saccharopolyspora erythraea iron-dependent regulator" (2022)
- Lucy C. Walters, Daniel Rozbesky, Karl Harlos, Max Quastel, Hong Sun, Sebastian Springer, Robert P. Rambo, Fiyaz Mohammed, E. Yvonne Jones, Andrew J. Mcmichael, Geraldine M. Gillespie, "Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes", Cell Reports, 39 (2022), DOI: 10.1016/j.celrep.2022.110959
- Matthew T. Warren, Iain Galpin, Muhammad Hasan, Steve Hindmarsh, John Padrnos, Charlotte J. C. Edwards-Gayle, Robert T. Mathers, Dave J. Adams, Gabriele Cesare Sosso, Matthew Ian Gibson, "Minimalistic ice recrystallisation inhibitors based on phenylalanine", Chemical Communications (2022), DOI: 10.1039/D2CC02531K
- Frederik G. Tidemand, Sara Blemmer, Nicolai T. Johansen, Lise Arleth, Martin Cramer Pedersen, "Non-ionic detergent assists formation of supercharged nanodiscs and insertion of membrane proteins", Biochimica Et Biophysica Acta (bba) - Biomembranes, 1864 (2022), DOI: 10.1016/j.bbamem.2022.183884
- [Thesis] Wenlong Zhu, "Structure and mechanism of two type III CRISPR defence nucleases activated by cyclic oligoadenylate" (2022)
- Sally Ryan, Kim Shortall, Michele Dully, Ahmed Djehedar, David Murray, James Butler, John Neilan, Tewfik Soulimane, Sarah P. Hudson, "Long acting injectables for therapeutic proteins", Colloids And Surfaces B: Biointerfaces, 8 (2022), DOI: 10.1016/j.colsurfb.2022.112644
- Christophe J. Lalaurie, Andrew Splevins, Teresa S. Barata, Karen A. Bunting, Daniel R. Higazi, Mire Zloh, Valentina A. Spiteri, Stephen J. Perkins, Paul A. Dalby, "Elucidation of critical pH-dependent structural changes in Botulinum Neurotoxin E", Journal Of Structural Biology, 12 (2022), DOI: 10.1016/j.jsb.2022.107876
- Michael H D'Souza, Tyler Mrozowich, Maulik D. Badmalia, Mitchell Geeraert, Angela Frederickson, Amy Henrickson, Borries Demeler, Michael t. Wolfinger, Trushar R. Patel, "Biophysical characterisation of human LincRNA-p21 sense and antisense Alu inverted repeats", Nucleic Acids Research, 50, 5881 - 5898 (2022), DOI: 10.1093/nar/gkac414
- David Fernandez-Justel, Íñigo Marcos‐alcalde, Federico Abascal, Nerea Vidaña, Paulino Gómez-Puertas, Alberto Jiménez, José L. Revuelta, Ruben M. Buey, "Diversity of mechanisms to control bacterial GTP homeostasis by the mutually exclusive binding of adenine and guanine nucleotides to IMP dehydrogenase", Protein Science, 31 (2022), DOI: 10.1002/pro.4314
- Benny D. Belviso, Giuseppe Felice Mangiatordi, Domenico Alberga, Vincenzo Mangini, Benedetta Carrozzini, Rocco Caliandro, "Structural characterization of the full-length anti-CD20 antibody rituximab", Frontiers In Molecular Biosciences, 9 (2022), DOI: 10.3389/fmolb.2022.823174
- Lauren A. Profitt, Richard H. G. Baxter, Ann M. Valentine, "Superstoichiometric binding of the anticancer agent titanocene dichloride by human serum transferrin and the accompanying lobe closure", Biochemistry, 271 (2022), DOI: 10.1021/acs.biochem.1c00813
- Lukas S. Stelzl, Lisa M. Pietrek, Andrea Holla, Javier Oroz, Mateusz Sikora, Jürgen Köfinger, Benjamin Schuler, Markus Zweckstetter, Gerhard Hummer, "Global structure of the intrinsically disordered protein tau emerges from its local structure", Jacs Au (2022), DOI: 10.1021/jacsau.1c00536
- Rodrigo Aguilar, Kerrie B. Spencer, Barry Kesner, Noreen F. Rizvi, Maulik D. Badmalia, Tyler Mrozowich, Jonathan D. Mortison, Carlos Rivera, Graham F. Smith, Julja Burchard, Peter J. Dandliker, Trushar R. Patel, Elliott B. Nickbarg, Jeannie T. Lee, "Targeting Xist with compounds that disrupt RNA structure and X inactivation", Nature (2022), DOI: 10.1038/s41586-022-04537-z
- Mikel García-Alija, Jonathan J. Du, Izaskun Ordóñez, Asier Diz-Vallenilla, Alicia Moraleda-Montoya, Nazneen Sultana, Chau G. Huynh, Chao Li, Thomas Connor Donahue, Lai-Xi Wang, Beatriz Trastoy, Eric J. Sundberg, Marcelo E. Guerin, "Mechanism of cooperative N-glycan processing by the multi-modular endoglycosidase EndoE", Nature Communications, 13 (2022), DOI: 10.1038/s41467-022-28722-w
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