Instruments by Science Group
Macromolecular
Soft Condensed 
Imaging and
Biological
Magnetic
Structures and
Crystallography 
Spectroscopy B21 Contact
Beamline phone numbers:
+44 (0) 1235 77 8627
+44 (0) 1235 77 8640
Principal Beamline Scientist:
Nathan Cowieson
Tel: +44 (0) 1235 567 504
E-mail: [email protected]
Science Group Leader
Robert Rambo
Email: [email protected]
Tel: +44 (0)1235 56 7675
B21 High Throughput SAXS
Status: Operational
Beamsize: <75 μm
Detector: Eiger 4M
Energy: 6 - 23 keV
Detector: Eiger 4M
Energy: 6 - 23 keV
15 items found for 2015 [total: 654]
Structure of the helicase domain of DNA polymerase theta reveals a possible role in the microhomology- mediated end-joining pathway Structure, 23 (12) Dec 2015 DOI: 10.1016/j.str.2015.10.014
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access
Structurally plastic peptide capsules for synthetic antimicrobial viruses Chemical Science, Dec 2015 DOI: 10.1039/C5SC03260A
Interaction of partially denatured insulin with a DSPC floating lipid bilayer Soft Matter, Nov 2015 DOI: 10.1039/C5SM02502H
Successful chemo drug monitoring Nov 2015
Science Highlight B21-High Throughput SAXS
Structural insights into the MMACHC-MMADHC protein complex involved in vitamin B12 trafficking Journal Of Biological Chemistry, Oct 2015 DOI: 10.1074/jbc.M115.683268
Insights into collagen uptake by C-type mannose receptors from the crystal structure of Endo180 domains 1–4 Structure, Oct 2015 DOI: 10.1016/j.str.2015.09.004
Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus Nature, 527 (7576) Oct 2015 DOI: 10.1038/nature15525
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes Chemical Communications, 51 Oct 2015 DOI: 10.1039/C5CC08224B
The copolymer blending method: a new approach for targeted assembly of micellar nanoparticles Macromolecules, 48 (18) Sept 2015 DOI: 10.1021/acs.macromol.5b01426
Characterisation of cytochrome c MtoD from the iron-oxidising autotroph Sideroxydans lithotrophicus ES-1 Sept 2015
Thesis B21-High Throughput SAXS I03-Macromolecular Crystallography
RAID3 - An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity Rna Biology, 12 Jul 2015 DOI: 10.1080/15476286.2015.1079681
Journal Paper B21-High Throughput SAXS
Structural characterisation of non-deamidated acidic variants of Erwinia chrysanthemi l-asparaginase using small-angle X-ray scattering and ion-mobility mass spectrometry Pharmaceutical Research, June 2015 DOI: 10.1007/s11095-015-1722-2
Journal Paper B21-High Throughput SAXS
Self-assembly and collagen-stimulating activity of a peptide amphiphile incorporating a peptide sequence from lumican Langmuir, 31 (15) Apr 2015 DOI: 10.1021/acs.langmuir.5b00057
Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes Nucleic Acids Research, Apr 2015 DOI: 10.1093/nar/gkv373
Formation of DNA-copolymer fibrils through an amyloid-like nucleation polymerization mechanism Macromolecular Rapid Communications, 36 (8) Feb 2015 DOI: 10.1002/marc.201400728
Journal Paper B21-High Throughput SAXS
- Joseph A. Newman, Christopher D. O. Cooper, Hazel Aitkenhead, Opher Gileadi, "Structure of the helicase domain of DNA polymerase theta reveals a possible role in the microhomology- mediated end-joining pathway", Structure, 23 (12), 2319 - 2330 (2015), DOI: 10.1016/j.str.2015.10.014
- Valeria Castelletto, Emiliana De Santis, Hasan Alkassem, Baptiste Lamarre, James Noble, Santanu Ray, Angelo Bella, Jonathan R. Burns, Bart W. Hoogenboom, Maxim G. Ryadnov, "Structurally plastic peptide capsules for synthetic antimicrobial viruses", Chemical Science (2015), DOI: 10.1039/C5SC03260A
- A. J. C. Dennison, R. A. L. Jones, R. A. Staniforth, A. J. Parnell, "Interaction of partially denatured insulin with a DSPC floating lipid bilayer", Soft Matter (2015), DOI: 10.1039/C5SM02502H
- [Science Highlight] Diamond Light Source, "Successful chemo drug monitoring" (2015)
- Sean Froese, Jolanta Kopec, Fiona Fitzpatrick, Marion Schuller, Thomas Mccorvie, Rod Chalk, Tanja Plessl, Victoria Fettelschoss, Brian Fowler, Matthias R. Baumgartner, Wyatt Yue, "Structural insights into the MMACHC-MMADHC protein complex involved in vitamin B12 trafficking", Journal Of Biological Chemistry (2015), DOI: 10.1074/jbc.M115.683268
- Patricia Paracuellos Torrecilla, David Briggs, Federico Carafoli, Tan Loncar, Erhard Hohenester, "Insights into collagen uptake by C-type mannose receptors from the crystal structure of Endo180 domains 1–4", Structure (2015), DOI: 10.1016/j.str.2015.09.004
- Narin Hengrung, Kamel El Omari, Itziar Serna Martin, Frank T. Vreede, Stephen Cusack, Robert P. Rambo, Clemens Vonrhein, Gérard Bricogne, David I. Stuart, Jonathan M. Grimes, Ervin Fodor, "Crystal structure of the RNA-dependent RNA polymerase from influenza C virus", Nature, 527 (7576), 114 - 117 (2015), DOI: 10.1038/nature15525
- Ian William Hamley, Steven Kirkham, Radoslaw M. Kowalczyk, Valeria Castelletto, Mehedi Reza, Janne Ruokolainen, "Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes", Chemical Communications, 51, 17680 - 17683 (2015), DOI: 10.1039/C5CC08224B
- Daniel B. Wright, Joseph P. Patterson, Anaïs Pitto-Barry, Annhelen Lu, Nigel Kirby, Nathan C. Gianneschi, Christophe Chassenieux, Olivier Colombani, Rachel K. O’reilly, "The copolymer blending method: a new approach for targeted assembly of micellar nanoparticles", Macromolecules, 48 (18), 6516 - 6522 (2015), DOI: 10.1021/acs.macromol.5b01426
- [Thesis] Christopher Robert Beckwith, "Characterisation of cytochrome c MtoD from the iron-oxidising autotroph Sideroxydans lithotrophicus ES-1" (2015)
- Florian Mittelberger, Cindy Meyer, Georg H. Waetzig, Martin Zacharias, Erica Valentini, Dmitri I. Svergun, Katharina Berg, Inken Lorenzen, Joachim Grötzinger, Stefan Rose-John, Ulrich Hahn, "RAID3 - An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity", Rna Biology, 12, 1043 - 1053 (2015), DOI: 10.1080/15476286.2015.1079681
- David Gervais, Darryl King, Patrick Kanda, Nicholas Foote, Lucy Elliott, Phillip Brown, Natacha O. Lee, Konstantinos Thalassinos, Claire Pizzey, Robert Rambo, Thomas C. Minshull, Mark J. Dickman, Stuart Smith, "Structural characterisation of non-deamidated acidic variants of Erwinia chrysanthemi l-asparaginase using small-angle X-ray scattering and ion-mobility mass spectrometry", Pharmaceutical Research (2015), DOI: 10.1007/s11095-015-1722-2
- Ian Hamley, Ashkan Dehsorkhi, Valeria Castelletto, Merlin N. M. Walter, Che Connon, Mehedi Reza, Janne Ruokolainen, "Self-assembly and collagen-stimulating activity of a peptide amphiphile incorporating a peptide sequence from lumican", Langmuir, 31 (15) (2015), DOI: 10.1021/acs.langmuir.5b00057
- Joseph A Newman, Pavel Savitsky, Charles K. Allerston, Anna H. Bizard, Ozgun Ozer, Kata Sarlos, Ying Liu, Els Pardon, Jan Steyaert, Ian D Hickson, Opher Gileadi, "Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes", Nucleic Acids Research (2015), DOI: 10.1093/nar/gkv373
- Dawid Kedracki, Sergey K. Filippov, Nidhi Gour, Helmut Schlaad, Corinne Nardin, "Formation of DNA-copolymer fibrils through an amyloid-like nucleation polymerization mechanism", Macromolecular Rapid Communications, 36 (8), 768 - 773 (2015), DOI: 10.1002/marc.201400728
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