Instruments by Science Group
Macromolecular
Soft Condensed 
Imaging and
Biological
Magnetic
Structures and
Crystallography 
Spectroscopy B21 Contact
Beamline phone numbers:
+44 (0) 1235 77 8627
+44 (0) 1235 77 8640
Principal Beamline Scientist:
Nathan Cowieson
Tel: +44 (0) 1235 567 504
E-mail: [email protected]
Science Group Leader
Robert Rambo
Email: [email protected]
Tel: +44 (0)1235 56 7675
B21 High Throughput SAXS
Status: Operational
Beamsize: <75 μm
Detector: Eiger 4M
Energy: 6 - 23 keV
Detector: Eiger 4M
Energy: 6 - 23 keV
60 items found for 2019 [total: 654]
Nano-encapsulated Escherichia coli divisome anchor ZipA, and in complex with FtsZ Scientific Reports, 9 Dec 2019 DOI: 10.1038/s41598-019-54999-x
Structural insights into the intracellular region of the human magnesium transport mediator CNNM4 International Journal Of Molecular Sciences, 20 Dec 2019 DOI: 10.3390/ijms20246279
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Exploring the role of elongation Factor-Like 1 (EFL1) in Shwachman-Diamond syndrome through molecular dynamics Journal Of Biomolecular Structure And Dynamics, Dec 2019 DOI: 10.1080/07391102.2019.1704883
Journal Paper B21-High Throughput SAXS
Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition Nucleic Acids Research, 37 Dec 2019 DOI: 10.1093/nar/gkz1163
A multi-pronged approach to understanding the form and function of hStaufen protein Rna, Dec 2019 DOI: 10.1261/rna.072595.119
Journal Paper B21-High Throughput SAXS
Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection Proceedings Of The National Academy Of Sciences, 64 Dec 2019 DOI: 10.1073/pnas.1911776116
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
Rapid and direct preparation of lignin nanoparticles from alkaline pulping liquor by mild ultrasonication Acs Sustainable Chemistry & Engineering, Nov 2019 DOI: 10.1021/acssuschemeng.9b05445
Journal Paper B21-High Throughput SAXS
The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion Journal Of Biological Chemistry, 294 Nov 2019 DOI: 10.1074/jbc.RA119.010771
Aldehyde-alcohol dehydrogenase forms a high-order spirosome architecture critical for its activity Nature Communications, 10 Oct 2019 DOI: 10.1038/s41467-019-12427-8
Sequential electrostatic assembly of a polymer surfactant corona increases activity of the phosphotriesterase arPTE Bioconjugate Chemistry, Oct 2019 DOI: 10.1021/acs.bioconjchem.9b00664
Asparagine-84, a regulatory allosteric site residue, helps maintain the quaternary structure of Campylobacter jejuni dihydrodipicolinate synthase Journal Of Structural Biology, Oct 2019 DOI: 10.1016/j.jsb.2019.107409
Journal Paper B21-High Throughput SAXS
Experimental determination of second virial coefficients by small-angle X-ray scattering: a problem revisited European Biophysics Journal, 346 Oct 2019 DOI: 10.1007/s00249-019-01404-0
Journal Paper B21-High Throughput SAXS
Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability Scientific Reports, 9 Sept 2019 DOI: 10.1038/s41598-019-49944-x
Integrative analysis of the dynamics of rhomboid protease GlpG from Escherichia coli Sept 2019
Thesis B21-High Throughput SAXS
Structures of influenza A virus RNA polymerase offer insight into viral genome replication Nature, 573 Sept 2019 DOI: 10.1038/s41586-019-1530-7
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Krios I-Titan Krios I at Diamond
Structural and biochemical insights into an engineered high-redox potential laccase overproduced in Aspergillus International Journal Of Biological Macromolecules, Sept 2019 DOI: 10.1016/j.ijbiomac.2019.09.052
Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum -infected erythrocytes Proceedings Of The National Academy Of Sciences, 8 Sept 2019 DOI: 10.1073/pnas.1911900116
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) open access
Double monoubiquitination modifies the molecular recognition properties of p15 PAF promoting binding to the reader module of Dnmt1 Acs Chemical Biology, Sept 2019 DOI: 10.1021/acschembio.9b00679
New structure for human flu virus protein Sept 2019
Science Highlight B21-High Throughput SAXS I03-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Krios I-Titan Krios I at Diamond
Multimodal control of liquid crystalline mesophases from surfactants with photoswitchable tails Journal Of Materials Chemistry C, 51 Aug 2019 DOI: 10.1039/C9TC04079J
Journal Paper B21-High Throughput SAXS
How the protein antibiotic pyocin S5 kills Pseudomonas aeruginosa Aug 2019
Thesis B21-High Throughput SAXS open access
Self-assembly, tunable hydrogel properties and selective anti- cancer activity of a carnosine-derived lipidated peptide Acs Applied Materials & Interfaces, Aug 2019 DOI: 10.1021/acsami.9b09065
The Bateman domain of IMP dehydrogenase is a binding target for dinucleoside polyphosphates Journal Of Biological Chemistry, Aug 2019 DOI: 10.1074/jbc.AC119.010055
Self-assembly of a catalytically active lipopeptide and its incorporation into cubosomes Acs Applied Bio Materials, Jul 2019 DOI: 10.1021/acsabm.9b00489
Designer artificial membrane binding proteins to direct stem cells to the myocardium Chemical Science, 20 Jul 2019 DOI: 10.1039/C9SC02650A
Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity Plos Pathogens, 15 Jul 2019 DOI: 10.1371/journal.ppat.1007458
Identification and characterization of mutations in ubiquitin required for non-covalent dimer formation Structure, Jul 2019 DOI: 10.1016/j.str.2019.06.008
Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) open access
Complementary substrate specificity and distinct quaternary assembly of the Escherichia coli aerobic and anaerobic beta-oxidation trifunctional enzyme complexes Biochemical Journal, June 2019 DOI: 10.1042/BCJ20190314
Journal Paper B21-High Throughput SAXS
Purification, functional characterization and crystallization of the PerR peroxide sensor from Saccharopolyspora erythraea June 2019
Thesis B21-High Throughput SAXS
Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism Nature Communications, 10 May 2019 DOI: 10.1038/s41467-019-09989-y
Structural studies of glycoside hydrolyses in solution using small-angle scattering (SAS) techniques May 2019 DOI: 10.11606/T.105.2019.tde-03052019-173258
Thesis B21-High Throughput SAXS
Solution structure and hydrodynamics of C. elegans UNC-6: a nematode paralogue of the vertebrate key axon guidance protein Netrin-1 Biophysical Journal, May 2019 DOI: 10.1016/j.bpj.2019.04.033
Journal Paper B21-High Throughput SAXS
Studies on the programmable protein assembly via genetically encoded native chemical ligation May 2019
Thesis B21-High Throughput SAXS
A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties Scientific Reports, 9 May 2019 DOI: 10.1038/s41598-019-44385-y
Melanin production by tyrosinase activity on a tyrosine-rich peptide fragment and pH-dependent self-assembly of its lipidated analogue Organic & Biomolecular Chemistry, 26 Apr 2019 DOI: 10.1039/C9OB00550A
Journal Paper B21-High Throughput SAXS
Crystallization and lamellar nanosheet formation of an aromatic dipeptoid Chemical Communications, 7 Apr 2019 DOI: 10.1039/C9CC02335F
Self-assembly, antimicrobial activity and membrane interactions of arginine-capped peptide bola-amphiphiles Acs Applied Bio Materials, Apr 2019 DOI: 10.1021/acsabm.9b00172
Colloidal self-assembly: particle synthesis, functionalisation and applications Apr 2019
Thesis B21-High Throughput SAXS
Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis Biochemical Journal, 476 Apr 2019 DOI: 10.1042/BCJ20180867
The molecular basis for apolipoprotein E4 as the major risk factor for late-onset Alzheimer's disease Journal Of Molecular Biology, Apr 2019 DOI: 10.1016/j.jmb.2019.04.019
Direct binding of the flexible C-terminal segment of Periaxin to β4 integrin suggests a molecular basis for CMT4F Frontiers In Molecular Neuroscience, 12 Apr 2019 DOI: 10.3389/fnmol.2019.00084
A molecular model for self-assembly of the synaptonemal complex protein SYCE3 Journal Of Biological Chemistry, Apr 2019 DOI: 10.1074/jbc.RA119.008404
Crystal structure and epitope analysis of house dust mite allergen Der f 21 Scientific Reports, 9 Mar 2019 DOI: 10.1038/s41598-019-40879-x
Dynamic ion pair behavior stabilizes single α-helices in proteins Journal Of Biological Chemistry, 294 Mar 2019 DOI: 10.1074/jbc.RA118.006752
Structure-self-assembly-function relationships of azobenzene photosurfactants Mar 2019
Thesis B21-High Throughput SAXS
Distinct USP25 and USP28 oligomerization states regulate deubiquitinating activity Molecular Cell, Mar 2019 DOI: 10.1016/j.molcel.2019.02.030
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) open access
Scalable geometrically designed protein cages assembled via genetically encoded split inteins Structure, Mar 2019 DOI: 10.1016/j.str.2019.02.005
Journal Paper B21-High Throughput SAXS
The biochemical and biophysical characterisation of protein antibiotics targeting Pectobacterium spp. and Streptococcus agalactiae Feb 2019
Thesis B21-High Throughput SAXS
Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation Scientific Reports, 9 Feb 2019 DOI: 10.1038/s41598-019-39722-0
A cholesterol analogue induces an oligomeric reorganization of VDAC Biophysical Journal, Feb 2019 DOI: 10.1016/j.bpj.2019.01.031
Journal Paper B21-High Throughput SAXS
Peptide-stabilized emulsions and gels from an arginine-rich surfactant-like peptide with antimicrobial activity Acs Applied Materials & Interfaces, Feb 2019 DOI: 10.1021/acsami.9b00581
Flexibility defines structure in crystals of amphiphilic DNA nanostars Journal Of Physics: Condensed Matter, 31 Feb 2019 DOI: 10.1088/1361-648X/aaf4a1
Molecular structure of human synaptonemal complex protein SYCE1 Chromosoma, 14 Jan 2019 DOI: 10.1007/s00412-018-00688-z
Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM Plos Pathogens, 15 Jan 2019 DOI: 10.1371/journal.ppat.1007537
The self-assembly of lipopeptides containing short peptide fragments derived from the gastrointestinal hormone PYY3-36: from micelles to amyloid fibrils The Journal Of Physical Chemistry B, Jan 2019 DOI: 10.1021/acs.jpcb.8b11097
A nucleotide-dependent conformational switch controls the polymerization of human IMP dehydrogenases to modulate their catalytic activity Journal Of Molecular Biology, Jan 2019 DOI: 10.1016/j.jmb.2019.01.020
Calicivirus VP2 forms a portal-like assembly following receptor engagement Nature, 565 Jan 2019 DOI: 10.1038/s41586-018-0852-1
Journal Paper B21-High Throughput SAXS
Lysyl oxidase–like 2 (LOXL2)–mediated cross-linking of tropoelastin The Faseb Journal, Jan 2019 DOI: 10.1096/fj.201801860RR
Towards an understanding of the self-assembly and applications of phospholipid-containing nanoparticles Jan 2019
Thesis B21-High Throughput SAXS
Crystalline frameworks self-assembled from amphiphilic DNA nanostructures Jan 2019 DOI: 10.17863/CAM.36954
- Sarah C. Lee, Richard Collins, Yu-Pin Lin, Mohammed Jamshad, Claire Broughton, Sarah A. Harris, Benjamin S. Hanson, Cecilia Tognoloni, Rosemary A. Parslow, Ann E. Terry, Alison Rodger, Corinne J. Smith, Karen J. Edler, Robert Ford, David I. Roper, Timothy R. Dafforn, "Nano-encapsulated Escherichia coli divisome anchor ZipA, and in complex with FtsZ", Scientific Reports, 9 (2019), DOI: 10.1038/s41598-019-54999-x
- Paula Gimenez Mascarell, Iker Oyenarte, Irene Gonzalez Recio, Carmen Fernandez-Rodriguez, María Ángeles Corral-Rodríguez, Igone Campos-Zarraga, Jorge Simón, Elie Kostantin, Serge Hardy, Antonio Diaz Quintana, Mara Zubillaga Lizeaga, Nekane Merino, Tammo Diercks, Francisco J. Blanco, Irene Diaz Moreno, María Luz Martínez-Chantar, Michel L. Tremblay, Dominik Müller, Dritan Siliqi, Luis Alfonso Martinez-Cruz, "Structural insights into the intracellular region of the human magnesium transport mediator CNNM4", International Journal Of Molecular Sciences, 20 (2019), DOI: 10.3390/ijms20246279
- Pietro Delre, Domenico Alberga, Abril Gijsbers, Nuria Sánchez-Puig, Orazio Nicolotti, Michele Saviano, Dritan Siliqi, Giuseppe Felice Mangiatordi, "Exploring the role of elongation Factor-Like 1 (EFL1) in Shwachman-Diamond syndrome through molecular dynamics", Journal Of Biomolecular Structure And Dynamics (2019), DOI: 10.1080/07391102.2019.1704883
- Deepak Kumar Yadav, Dagmar Zigáčková, Maria Zlobina, Tomas Klumpler, Christelle Beaumont, Monika Kubíčková, Štěpánka Vaňáčová, Peter J. Lukavsky, "Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition", Nucleic Acids Research, 37 (2019), DOI: 10.1093/nar/gkz1163
- Silvia Visentin, Giuseppe Cannone, James Doutch, Gemma Harris, Michael L. Gleghorn, Luke Clifton, Brian O. Smith, Laura Spagnolo, "A multi-pronged approach to understanding the form and function of hStaufen protein", Rna (2019), DOI: 10.1261/rna.072595.119
- Fiona Whelan, Aleix Lafita, Samuel C. Griffiths, Rachael E. M. Cooper, Jean L. Whittingham, Johan P. Turkenburg, Iain W. Manfield, Alexander N. St. John, Emanuele Paci, Alex Bateman, Jennifer R. Potts, "Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection", Proceedings Of The National Academy Of Sciences, 64 (2019), DOI: 10.1073/pnas.1911776116
- Melissa B. Agustin, Paavo A. Penttilä, Maarit Lahtinen, Kirsi S. Mikkonen, "Rapid and direct preparation of lignin nanoparticles from alkaline pulping liquor by mild ultrasonication", Acs Sustainable Chemistry & Engineering (2019), DOI: 10.1021/acssuschemeng.9b05445
- Caroline Ridley, Michael P. Lockhart-Cairns, Richard F. Collins, Thomas A. Jowitt, Durai B. Subramani, Mehmet Kesimer, Clair Baldock, David J. Thornton, "The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion", Journal Of Biological Chemistry, 294, 17105 - 17116 (2019), DOI: 10.1074/jbc.RA119.010771
- Gijeong Kim, Liyana Azmi, Seongmin Jang, Taeyang Jung, Hans Hebert, Andrew J. Roe, Olwyn Byron, Ji-Joon Song, "Aldehyde-alcohol dehydrogenase forms a high-order spirosome architecture critical for its activity", Nature Communications, 10 (2019), DOI: 10.1038/s41467-019-12427-8
- William Zhang, Benjamin M. Carter, Graham Day, Norman Govan, Colin J. Jackson, Adam Perriman, "Sequential electrostatic assembly of a polymer surfactant corona increases activity of the phosphotriesterase arPTE", Bioconjugate Chemistry (2019), DOI: 10.1021/acs.bioconjchem.9b00664
- Mohadeseh Majdi Yazdi, Sagar Saran, Tyler Mrozowich, Cheyanne Lehnert, Trushar R. Patel, David A. R. Sanders, David R. J. Palmer, "Asparagine-84, a regulatory allosteric site residue, helps maintain the quaternary structure of Campylobacter jejuni dihydrodipicolinate synthase", Journal Of Structural Biology (2019), DOI: 10.1016/j.jsb.2019.107409
- Tyler Mrozowich, Donald J. Winzor, David J. Scott, Trushar R. Patel, "Experimental determination of second virial coefficients by small-angle X-ray scattering: a problem revisited", European Biophysics Journal, 346 (2019), DOI: 10.1007/s00249-019-01404-0
- Catarina S. Tomé, Raquel R. Lopes, Pedro M. F. Sousa, Mariana P. Amaro, João Leandro, Haydyn D. T. Mertens, Paula Leandro, João B. Vicente, "Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability", Scientific Reports, 9 (2019), DOI: 10.1038/s41598-019-49944-x
- [Thesis] Yasser Almeida-Hernández, "Integrative analysis of the dynamics of rhomboid protease GlpG from Escherichia coli" (2019)
- Haitian Fan, Alexander P. Walker, Loic Carrique, Jeremy Keown, Itziar Serna Martin, Dimple Karia, Jane Sharps, Narin Hengrung, Els Pardon, Jan Steyaert, Jonathan M. Grimes, Ervin Fodor, "Structures of influenza A virus RNA polymerase offer insight into viral genome replication", Nature, 573, 287 - 290 (2019), DOI: 10.1038/s41586-019-1530-7
- Felipe De Salas, Rubén Cañadas, Gerard Santiago, Alicia Virseda-Jerez, Jesper Vind, Patrizia Gentili, Angel T. Martínez, Víctor Guallar, Ines G. Munoz, Susana Camarero, "Structural and biochemical insights into an engineered high-redox potential laccase overproduced in Aspergillus", International Journal Of Biological Macromolecules (2019), DOI: 10.1016/j.ijbiomac.2019.09.052
- Frank Lennartz, Cameron Smith, Alister G. Craig, Matthew K. Higgins, "Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum -infected erythrocytes", Proceedings Of The National Academy Of Sciences, 8 (2019), DOI: 10.1073/pnas.1911900116
- Amaia Gonzalez-Magaña, Alain Ibáñez De Opakua, Nekane Merino, Hugo Monteiro, Tammo Diercks, Javier Murciano-Calles, Irene Luque, Pau Bernadó, Tiago Cordeiro, Alfredo De Biasio, Francisco J Blanco, "Double monoubiquitination modifies the molecular recognition properties of p15 PAF promoting binding to the reader module of Dnmt1", Acs Chemical Biology (2019), DOI: 10.1021/acschembio.9b00679
- [Science Highlight] Diamond Light Source, "New structure for human flu virus protein" (2019)
- Judith E. Houston, Elaine A. Kelly, Margarita Kruteva, Kiriaki Chrissopoulou, Nathan Cowieson, Rachel C. Evans, "Multimodal control of liquid crystalline mesophases from surfactants with photoswitchable tails", Journal Of Materials Chemistry C, 51 (2019), DOI: 10.1039/C9TC04079J
- [Thesis] Hannah Behrens, "How the protein antibiotic pyocin S5 kills Pseudomonas aeruginosa" (2019)
- Valeria Castelletto, Charlotte J. C. Edwards-Gayle, Francesca Greco, Ian W. Hamley, Dr Jani Seitsonen, Janne Ruokolainen, "Self-assembly, tunable hydrogel properties and selective anti- cancer activity of a carnosine-derived lipidated peptide", Acs Applied Materials & Interfaces (2019), DOI: 10.1021/acsami.9b09065
- David Fernandez-Justel, Rafael Peláez, José Luis Revuelta, Ruben M. Buey, "The Bateman domain of IMP dehydrogenase is a binding target for dinucleoside polyphosphates", Journal Of Biological Chemistry (2019), DOI: 10.1074/jbc.AC119.010055
- Valeria Castelletto, Charlotte J. C. Edwards-Gayle, Ian W. Hamley, Juliane N. B. D. Pelin, Wendel Andrade Alves, Andrea Aguilar, Jani Seitsonen, Janne Ruokolainen, "Self-assembly of a catalytically active lipopeptide and its incorporation into cubosomes", Acs Applied Bio Materials (2019), DOI: 10.1021/acsabm.9b00489
- Wenjin Xiao, Thomas I. P. Green, Xiaowen Liang, Rosalia Cuahtecontzi Delint, Guillaume Perry, Michael S. Roberts, Kristian Le Vay, Catherine R. Back, Raimomdo Ascione, Haolu Wang, Paul R. Race, Adam W. Perriman, "Designer artificial membrane binding proteins to direct stem cells to the myocardium", Chemical Science, 20 (2019), DOI: 10.1039/C9SC02650A
- Rajesh Ponnusamy, Ritika Khatri, Paulo B. Correia, C. David Wood, Erika J. Mancini, Paul J. Farrell, Michelle J. West, "Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity", Plos Pathogens, 15 (2019), DOI: 10.1371/journal.ppat.1007458
- Mads Gabrielsen, Lori Buetow, Dominika Kowalczyk, Wei Zhang, Sachdev S. Sidhu, Danny Huang, "Identification and characterization of mutations in ubiquitin required for non-covalent dimer formation", Structure (2019), DOI: 10.1016/j.str.2019.06.008
- Shiv Sah-Teli, Mikko J. Hynönen, Werner Schmitz, James A. Geraets, Jani Seitsonen, Jan Skov Pedersen, Sarah J. Butcher, Rik .k. Wierenga, Rajaram Venkatesan, "Complementary substrate specificity and distinct quaternary assembly of the Escherichia coli aerobic and anaerobic beta-oxidation trifunctional enzyme complexes", Biochemical Journal (2019), DOI: 10.1042/BCJ20190314
- [Thesis] Grim Elison Kalman, "Purification, functional characterization and crystallization of the PerR peroxide sensor from Saccharopolyspora erythraea" (2019)
- Nicholas G. Fox, Xiaodi Yu, Xidong Feng, Henry J. Bailey, Alain Martelli, Joseph F. Nabhan, Claire Strain-Damerell, Christine Bulawa, Wyatt W. Yue, Seungil Han, "Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism", Nature Communications, 10 (2019), DOI: 10.1038/s41467-019-09989-y
- [Thesis] Piiadov Vasilii, "Structural studies of glycoside hydrolyses in solution using small-angle scattering (SAS) techniques" (2019), DOI: 10.11606/T.105.2019.tde-03052019-173258
- Natalie Krahn, Markus Meier, Raphael Reuten, Manuel Koch, Joerg Stetefeld, Trushar R. Patel, "Solution structure and hydrodynamics of C. elegans UNC-6: a nematode paralogue of the vertebrate key axon guidance protein Netrin-1", Biophysical Journal (2019), DOI: 10.1016/j.bpj.2019.04.033
- [Thesis] Wan Ling Won, "Studies on the programmable protein assembly via genetically encoded native chemical ligation" (2019)
- Charlotte E. Mardle, Thomas J. Shakespeare, Louise E. Butt, Layla R. Goddard, Darren M. Gowers, Helen S. Atkins, Helen A. Vincent, Anastasia J. Callaghan, "A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties", Scientific Reports, 9 (2019), DOI: 10.1038/s41598-019-44385-y
- Jessica A. Hutchinson, Ian W. Hamley, Charlotte J. C. Edwards-Gayle, Valeria Castelletto, Cristian Piras, Rainer Cramer, Radoslaw Kowalczyk, Jani Seitsonen, Janne Ruokolainen, Robert P. Rambo, "Melanin production by tyrosinase activity on a tyrosine-rich peptide fragment and pH-dependent self-assembly of its lipidated analogue", Organic & Biomolecular Chemistry, 26 (2019), DOI: 10.1039/C9OB00550A
- Valeria Castelletto, Ann M. Chippindale, Ian W. Hamley, Sarah Barnett, Abshar Hasan, King Hang Aaron Lau, "Crystallization and lamellar nanosheet formation of an aromatic dipeptoid", Chemical Communications, 7 (2019), DOI: 10.1039/C9CC02335F
- Charlotte J. C. Edwards-Gayle, Valeria Castelletto, Ian W. Hamley, Glyn Barrett, Francesca Greco, Daniel Hermida-Merino, Robert P. Rambo, Jani Seitsonen, Janne Ruokolainen, "Self-assembly, antimicrobial activity and membrane interactions of arginine-capped peptide bola-amphiphiles", Acs Applied Bio Materials (2019), DOI: 10.1021/acsabm.9b00172
- [Thesis] M. Zupkauskas, "Colloidal self-assembly: particle synthesis, functionalisation and applications" (2019)
- Fiona J. Sorrell, Lena M. Kilian, Jonathan M. Elkins, "Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis", Biochemical Journal, 476, 1037 - 1051 (2019), DOI: 10.1042/BCJ20180867
- Ana-Caroline Raulin, Lucas Kraft, Youssra K. Al-Hilaly, Wei-Feng Xue, John E. Mcgeehan, John R. Atack, Louise Serpell, "The molecular basis for apolipoprotein E4 as the major risk factor for late-onset Alzheimer's disease", Journal Of Molecular Biology (2019), DOI: 10.1016/j.jmb.2019.04.019
- Arne Raasakka, Helen Linxweiler, Peter J. Brophy, Diane L. Sherman, Petri Kursula, "Direct binding of the flexible C-terminal segment of Periaxin to β4 integrin suggests a molecular basis for CMT4F", Frontiers In Molecular Neuroscience, 12 (2019), DOI: 10.3389/fnmol.2019.00084
- Orla M. Dunne, Owen R. Davies, "A molecular model for self-assembly of the synaptonemal complex protein SYCE3", Journal Of Biological Chemistry (2019), DOI: 10.1074/jbc.RA119.008404
- Sze Lei Pang, Kok Lian Ho, Jitka Waterman, Robert Paul Rambo, Aik-Hong Teh, Indran Mathavan, Gemma Harris, Konstantinos Beis, Yee-How Say, Matta Sri Anusha, Yang Yie Sio, Fook Tim Chew, Chyan Leong Ng, "Crystal structure and epitope analysis of house dust mite allergen Der f 21", Scientific Reports, 9 (2019), DOI: 10.1038/s41598-019-40879-x
- Matthew Batchelor, Marcin Wolny, Emily G. Baker, Emanuele Paci, Arnout P. Kalverda, Michelle Peckham, "Dynamic ion pair behavior stabilizes single α-helices in proteins", Journal Of Biological Chemistry, 294, 3219 - 3234 (2019), DOI: 10.1074/jbc.RA118.006752
- [Thesis] Camille Blayo, "Structure-self-assembly-function relationships of azobenzene photosurfactants" (2019)
- Malte Gersch, Jane L. Wagstaff, Angela V. Toms, Bradford Graves, Stefan M. V. Freund, David Komander, "Distinct USP25 and USP28 oligomerization states regulate deubiquitinating activity", Molecular Cell (2019), DOI: 10.1016/j.molcel.2019.02.030
- James N. Wright, Wan Ling Wong, Joseph A. Harvey, James A. Garnett, Laura S. Itzhaki, Ewan R. G. Main, "Scalable geometrically designed protein cages assembled via genetically encoded split inteins", Structure (2019), DOI: 10.1016/j.str.2019.02.005
- [Thesis] Catriona Thompson, "The biochemical and biophysical characterisation of protein antibiotics targeting Pectobacterium spp. and Streptococcus agalactiae" (2019)
- Albert Castellví, Isidro Crespo, Eva Crosas, Ana Cámara-Artigas, Jose A. Gavira, Miguel A. G. Aranda, Xavier Parés, Jaume Farrés, Judith Juanhuix, "Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation", Scientific Reports, 9 (2019), DOI: 10.1038/s41598-019-39722-0
- Fraser G. Ferens, Trushar R. Patel, George Orriss, Deborah A. Court, Jörg Stetefeld, "A cholesterol analogue induces an oligomeric reorganization of VDAC", Biophysical Journal (2019), DOI: 10.1016/j.bpj.2019.01.031
- Valeria Castelletto, Charlotte J. C. Edwards-Gayle, Ian W. Hamley, Glyn Barrett, Jani Seitsonen, Janne Ruokolainen, "Peptide-stabilized emulsions and gels from an arginine-rich surfactant-like peptide with antimicrobial activity", Acs Applied Materials & Interfaces (2019), DOI: 10.1021/acsami.9b00581
- Ryan Brady, Will T. Kaufhold, Nicholas J. Brooks, Vito Foderà, Lorenzo Di Michele, "Flexibility defines structure in crystals of amphiphilic DNA nanostars", Journal Of Physics: Condensed Matter, 31 (2019), DOI: 10.1088/1361-648X/aaf4a1
- Orla M. Dunne, Owen R. Davies, "Molecular structure of human synaptonemal complex protein SYCE1", Chromosoma, 14 (2019), DOI: 10.1007/s00412-018-00688-z
- Tommaso Tosi, Fumiya Hoshiga, Charlotte Millership, Rahul Singh, Charles Eldrid, Delphine Patin, Dominique Mengin-Lecreulx, Konstantinos Thalassinos, Paul Freemont, Angelika Gründling, "Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM", Plos Pathogens, 15 (2019), DOI: 10.1371/journal.ppat.1007537
- Jessica A. Hutchinson, Ian W. Hamley, Juan Torras, Carlos Alemán, Dr Jani Seitsonen, Janne Ruokolainen, "The self-assembly of lipopeptides containing short peptide fragments derived from the gastrointestinal hormone PYY3-36: from micelles to amyloid fibrils", The Journal Of Physical Chemistry B (2019), DOI: 10.1021/acs.jpcb.8b11097
- David Fernandez-Justel, Rafael Nunez, Jaime Martin-Benito, David Jimeno, Adrián González-López, Eva María Soriano, José Luis Revuelta, Ruben M. Buey, "A nucleotide-dependent conformational switch controls the polymerization of human IMP dehydrogenases to modulate their catalytic activity", Journal Of Molecular Biology (2019), DOI: 10.1016/j.jmb.2019.01.020
- Michaela J. Conley, Marion Mcelwee, Liyana Azmi, Mads Gabrielsen, Olwyn Byron, Ian G. Goodfellow, David Bhella, "Calicivirus VP2 forms a portal-like assembly following receptor engagement", Nature, 565, 377 - 381 (2019), DOI: 10.1038/s41586-018-0852-1
- Christian E. H. Schmelzer, Andrea Heinz, Helen Troilo, Michael P. Lockhart-Cairns, Thomas A. Jowitt, Marion F. Marchand, Laurent Bidault, Marine Bignon, Tobias Hedtke, Alain Barret, James C. Mcconnell, Michael J. Sherratt, Stéphane Germain, David J. S. Hulmes, Clair Baldock, Laurent Muller, "Lysyl oxidase–like 2 (LOXL2)–mediated cross-linking of tropoelastin", The Faseb Journal (2019), DOI: 10.1096/fj.201801860RR
- [Thesis] Stephen C. L. Hall, "Towards an understanding of the self-assembly and applications of phospholipid-containing nanoparticles" (2019)
- [Thesis] Ryan Brady, "Crystalline frameworks self-assembled from amphiphilic DNA nanostructures" (2019), DOI: 10.17863/CAM.36954
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