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Elastin is the most abundant protein in mammalian elastic tissues and is responsible for their elastic recoil and resilience. Elastin dominates ...
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Flavopiridol was discovered to have anti-cancer properties in 19921, specifically by binding to cyclin-dependant kinases (CDKs) and inhibiting ...
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Transcriptional repression in eukaryotes requires the recruitment of large protein complexes to gene promoters and enhancers. These complexes ...
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Our indigenous gut microbiota play an important role in maintaining normal health and nutrition. They provide us with traits that the human genome ...
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Lentiviruses are associated with chronic disease states in a variety of mammals. However, until recently it was thought that these pathogens had ...
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The majority of bacterial gene regulators bind as symmetric dimers to palindromic DNA operators. Multimeric forms of proteins, including ...
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There are literally astronomical numbers of bacteriophages on Earth. These are viral parasites of bacteria and as such generate an immense ...
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The intricate wiring of the human brain requires cell surface signalling systems to guide the growing neurites to their correct locations. Indeed, ...
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G protein coupled receptors (GPCRs) are a large family of proteins that span the cell membrane of eukaryotes and consist of seven transmembrane ...
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Optimizing the electronic and magnetic properties of layered magnetic heterostructures for specific applications remains a challenging task for ...
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The spin-torque resonance effect on domain walls is an exciting new line of research for spintronic devices such as race-track memory and magnetic ...
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All living cells require energy, usually provided in the form of ATP, to carry out fundamental processes like movement and growth. Therefore, ...
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The anaphase promoting complex or cyclosome (APC/C) is a multi-subunit cullin-RING E3 ubiquitin ligase that functions to regulate progression ...
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Liquid crystals have transformed our daily lives, with the LCD industry currently being worth £300 bn per year worldwide. The nematic phase, the ...
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Organic photovoltaic (PV) materials have long-term promise for large area devices on flexible substrates produced by low-cost processes such as ...
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Our society takes for granted the high performance aluminium alloys used in aircraft, trains, fast ferries and motor vehicles. This high ...
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Synchrotron applications such as coherent X-ray diffraction and X-ray photon-correlation spectroscopy require detectors with a very small pixel ...
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Solid-state materials, particularly those performing useful functions (e.g. zeolites), often form frameworks or cellular structures on the ...
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Magnetic recording lies at the heart of many modern electronic devices. The density at which information can be stored is directy related to the ...
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Despite decades of study, the mechanisms that HIV employs at certain steps of its replication cycle remain relatively nebulous. One such step ...
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