Diamond-II Webinar: I24 KMX Upgrade Proposal

Nov 03. till Nov 03.

Diamond-II Webinar: I24 KMX Upgrade Proposal

This webinar is your opportunity to gain insight into the proposed substantial upgrade to Beamline I24 for Diamond-II, a co-ordinated programme of development that includes a major machine upgrade to a low emittance storage ring at higher energy, as well as a portfolio of new and rebuilt beamlines and enhancements to existing ones. This proposal offers an exciting and transformational change for the MX and I24 user community, so attendance is highly encouraged.

03/11/20202020-11-03T16:00:00 - 03/11/20202020-11-03T17:00:00
16:00 - 17:00
Online via Zoom

About the upgrade

The new beamline, called I24 KMX (kinetic macromolecular crystallography) will significantly enhance the capability of I24 in the measurement of high quality, low-dose, microsecond time-resolved (TR) MX data from cryo-cooled and room temperature 1 – 10 micron-sized crystals. Critically it will build upon I24’s strong track record in delivering high quality microfocus capability by further optimising the beam parameters, experimental setup and detectors to improve signal to noise. In the area of TR crystallography, I24 KMX will provide well-integrated tools for initiating and tracking reactions in the microsecond to second time domain, thereby complementing the femto- to nano-second time resolution that can be achieved at XFELs. The project goal will be to enable routine microsecond, microbeam SSX capability within the envelope of a world-class microfocus structural biology beamline.

Recent work at I24 has demonstrated that the combination of microfocus and serial crystallography is a powerful one. The proposed I24 KMX upgrade will seek to build on this blurring of the boundary between ‘traditional’ multi-crystal microfocus MX and serial approaches by allowing much of the same infrastructure to be exploited for each. I24 KMX will offer routine pin and serial MX with in situ validation of intermediate states and appraisal of radiation induced damage through the integration of complementary data such as XES and other spectroscopies.


Find out more about the Diamond-II programme here, and download the Diamond-II | Advancing Science science case here.

This webinar forms part of the second stage of user engagement for the Group's proposal. In 2018, an introductory workshop was held for users to discuss the project's potential benefits for research and to help further develop the science case and direction for the machine upgrade. You can revisit the event page here.

The business case for flagship beamline projects was presented to the Diamond Science Advisory Committee (SAC) and Diamond Industrial Science Committee (DISCo) in May, who recommended that a full business case should be put together for each new beamline or upgrade proposal. The Diamond team for each proposal has formed its own User Working Group with representatives from the User Community, who will build the finalised business cases, to be put forward to SAC/DISCo for consideration and prioritisation in December 2020.

User engagement and input is therefore vital for this proposal to build the strongest case possible and ensure key capabilities are captured.

Keep informed

If you are interested in keeping up to date on the I24 KMX Working Group progress and would like to receive updates by email, please sign up to our I24 KMX Flagship Interest Group by filling out this quick form.

You are also welcome to contact the project lead Robin Owen or working group chair Mike Hough with any questions or feedback.

If you have any questions about the webinar itself, please email the Diamond Events Team.

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