Diamond-II Workshop: MX & Soft Condensed Matter

Sep 10. till Sep 11.

Benefits & opportunities of the Diamond upgrade for MX & Soft Condensed Matter

The aims of this workshop are to introduce Diamond-II, to discuss its potential benefits for the existing facilities, and to develop the science case for the machine upgrade.

Date
10/09/20182018-09-10 - 11/09/20182018-09-11
Location
Diamond Light Source

Registration

Registration is now closed.

 

Please contact events@diamond.ac.uk with any queries.
 

Accommodation

There are a number of hotels and bed-and-breakfast options in the immediate vicinity of Diamond.
Prices per night will vary. Please enquire directly with your hotel of choice for details. 

Hotels within a short driving distance of Diamond include:

Diamond is approximately 30 minutes drive from Oxford city centre which has a wide range of hotels and accommodation options.

 

Outline schedule

 

Day 1: MX Workshop - 10th September

09:45
Registration
 
 Session 1: Opportunities of the Diamond-II upgrade for MX beamlines
10:30
D-II and Grand Challenges
Dave Stuart (DLS, Oxford)
10:55
D-II Impact for MX beamlines
Dave Hall (DLS)
11:20
XChem and beamline move
Frank von Delft (DLS, Oxford)
11:45
Bang for your buck - getting the best data with D-II
Gwyndaf Evans (DLS)
12:10
Lunch
 
13:10
The future of cryo-samples - automation and streamlining
Katherine McAuley (DLS)
13:35
Future of phasing and exploiting tuneability
Armin Wagner (DLS)
14:00
Discussion
 
14:30
Coffee
 
 Session 2: Serial crystallography and time resolved experiments

15:00
Introduction to Serial crystallography
Robin Owen (DLS)
15:15
Opportunities for rapid and time resolved serial crystallography
Mike Hough (University of Essex)
15:40
What does D-II mean for the XFEL-Hub
Allen Orville (DLS)
16:05
MX at SLS and SwissFEL
Meitian Wang (Paul Scherrer Institut)
16:30
Discussion
 
17:00
Coffee
 
Session 3: Structural biology needs for the future

17:25
Elucidating mechanism of biotechnologically relevant enzymes, the need for time resolved approaches
Colin Levy (University of Manchester
17:50
TBA
Susan Lea (University of Oxford)
18:15
Discussion
 
19:00
Dinner
 
 
 
Day 1: Soft Condensed Matter Workshop - 10th September
09:45
Registration
 
10:30
SCM beam line introduction
Rob Rambo (DLS)
10:45
I22
Nick Terrill (DLS)
11:05
B23
Giuliano Siligardi (DLS)
11:25
B22
Gianfelice Cinque (DLS)
11:45
B21
Nathan Cowieson (DLS)
12:05
Lunch
 
13:00
SAXS tomography
TBA
13:20
CD MMP for imaging
Bart Kahr (NYU)
13:40
nano IR tomography 
Luca Quaroni (Jagiellonian University, Poland)
14:00
THZ MOF
Jin-Chong Tan (University of Oxford)
14:20
Discussion
 
14:50
Coffee
 
15:20
Applications of Microfluidics on I22
TBA
15:40
Applications of Microfluidics on B23
Jerome Charmet (Warwick University)
16:00
Applications of Microfluidics on B22
Russel Howe (Aberdeen University)
16:20
SOLEIL microfluidics
Benedikt Lassalle (SOLEIL)
16:40
Discussion
 
17:10
Coffee
 
17:30
XFMS
Peter Stockley (Lees U)/Sayan Gupta (ALS)
17:50
TBA
 
18:10
B22 In situ time-resolved electrochemistry and correlated IR molecular analysis (faster and signal-to-noise)
Kylie Vincent (University of Oxford)
18:30
IR imaging and correlative studies
Rohit Bhargava
18:50
Discussion
 
19:00
Dinner
 
 
 
Day 2: Joint MX and Soft Condensed Matter Workshop - 11th September
 
Session 1: High throughput methods and drug discovery

09:00
High-Throughput Methods and Drug Discovery Introduction
Dave Brown (University of Kent)
09:10
MPS1 inhibitors and the molecular basis of resistance to MPS1 inhibition
Rob van Montfort (ICR)
09:35
Drug Discovery an industrial perspective
Rob Cooke (Heptares)
10:00
Protein Engineering/Ligand Screening SAXS 
Greg Hura (ALS, Berkeley)
10:25
Coffee
 
10:55
CD based screening method
Lorenzo Di Bari (Pisa U.)
11:20
High-throughput GI-SAXS
Alex Hexemer(ALS, Berkeley)
11:45
Discussion
 
12:15
Lunch
 
 
Data deluge
 
13:15
Data handling at Diamond
Andrew Richards (DLS)
13:40
Data analysis for integrated biology at Diamond
Alun Ashton (DLS)
14:05
Data mining science
A Hexemer (ALS, Berkeley)
14:30
Discussion
 
15:00
Coffee
 
 
Broader topics
 
15:30
X-ray crystallography of large complexes in the age of cryo-EM
Ashwin Chari (Max Planck, Gottingen)
15:55
The ESRF upgrade - impact on MX and SAXS for users
Jean Susini (ESRF)
16:20
Mono and Pink beam SSX and Life Science with APS-U
Bob Fischetti (APS, Chicago)
16:45
Discussions and Conclusions
 

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