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  1. Science
  2. Research
  3. Science Highlights
  4. 2011

  • Molecular knots

    Molecular knots Dec 21, 2011

    Diamond Light Source has recently played a key role in helping to reveal the exact structure of the most complex non-DNA molecular knot prepared ...

  • Studying dust frozen in time Dec 8, 2011

    Ice cores drilled from the frozen Antarctic landscape are made up of layer upon layer of frozen snow, dating back hundreds of thousands of years. ...

  • Broken heart valves

    Broken heart valves Nov 22, 2011

    Artificial heart valves have been used since the 1960s to replace natural heart valves damaged through disease. Each of four valves enables ...

  • Protecting Historic Parchment

    Protecting Historic Parchment Nov 9, 2011

    Parchment has been used for recording historical information since at least the 2nd century BC and makes an important contribution to our nation’s ...

  • Better LEDs

    Better LEDs Nov 9, 2011

    With the phase-out of incandescent light bulbs becoming more common around the world, there is a need to investigate more efficient and robust ...

  • Structural properties of thin layered materials from X-ray standing wave enhanced elastic and inelastic scattering

    Structural properties of thin layered materials from X-ray standing wave enhanced elastic and inelastic scattering Nov 9, 2011

    Thin multilayer structures comprising of thin layers of alternating elements or compounds find widespread technological applications – be it the ...

  • Towards understanding nanotoxicology Oct 28, 2011

    Nanoparticles have been incorporated in many consumer products, however their safety and toxicity have not been clearly identified. This is made ...

  • Huntington's disease

    Huntington's disease Oct 20, 2011

    Huntington’s disease (HD) is a dominantly-inherited neuropsychiatric disorder. Typically the symptoms begin in adulthood, slowly progressing from ...

  • A role for gold in cancer treatment?

    A role for gold in cancer treatment? Oct 18, 2011

    During the course of their treatment, around half of cancer patients receive some type of radiation therapy. This therapy is widely used to target ...

  • Proteins could offer novel antibiotic target

    Proteins could offer novel antibiotic target Oct 5, 2011

    Bacteria are single-celled organisms that inhabit almost every environment on the planet, including the bodies of humans and animals. The cell ...

  • Fighting drug-resistant infections

    Fighting drug-resistant infections Sep 6, 2011

    A breakthrough in the fight against drug-resistant infections is one step closer following the discovery of the structure of NDM-1: a vicious form ...

  • Protecting herbarium staff from mercury contaminated specimens

    Protecting herbarium staff from mercury contaminated specimens Aug 22, 2011

    The University of Manchester museum herbarium was founded in 1860 and contains over a million specimens from all over the world, with collections ...

  • Structural study shows how plant pathogens evolve to attack our vegetables

    Structural study shows how plant pathogens evolve to attack our vegetables Aug 18, 2011

    Fungus-like eukaryotic plant pathogens of the genus Phytophthora are devastating to root crops and vegetables because the effector proteins they ...

  • Improving corneal surgery

    Improving corneal surgery Jul 27, 2011

    The cornea is the external lens of the eye, responsible for refracting incoming light onto the crystalline lens behind, which in turn focuses it ...

  • Virus family tree

    Virus family tree Jul 13, 2011

    Just as humans have an ancestry, so too do viruses. But whereas we can use fossils to help identify the creatures that roamed the earth before us, ...

  • Nanostructure and elastic properties of human tropoelastin

    Nanostructure and elastic properties of human tropoelastin Jun 8, 2011

    Elastin is the most abundant protein in mammalian elastic tissues and is responsible for their elastic recoil and resilience. Elastin dominates ...

  • Aiding the development of an anti-cancer drug

    Aiding the development of an anti-cancer drug Jun 8, 2011

    Flavopiridol was discovered to have anti-cancer properties in 19921, specifically by binding to cyclin-dependant kinases (CDKs) and inhibiting ...

  • Toxin-antitoxin induced altruism in bacteria protects populations from bacteriophage infection

    Toxin-antitoxin induced altruism in bacteria protects populations from bacteriophage infection Jun 3, 2011

    There are literally astronomical numbers of bacteriophages on Earth. These are viral parasites of bacteria and as such generate an immense ...

  • The semaphorin-plexin system: a structural and functional analysis of cell guidance

    The semaphorin-plexin system: a structural and functional analysis of cell guidance Jun 3, 2011

    The intricate wiring of the human brain requires cell surface signalling systems to guide the growing neurites to their correct locations. Indeed, ...

  • TBL1 serves as a tetrameric scaffold for the assembly of the SMRT/NCoR transcriptional repression machinery

    TBL1 serves as a tetrameric scaffold for the assembly of the SMRT/NCoR transcriptional repression machinery Jun 3, 2011

    Transcriptional repression in eukaryotes requires the recruitment of large protein complexes to gene promoters and enhancers. These complexes ...

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