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          • A novel dynamic flow system for chemical analysis of live biological cells
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  1. Diamond Light Source
  2. News & Literature
  3. Annual Review
  4. Diamond Annual Review 2019
  5. Science Group Updates
  6. Soft Condensed Matter Group

Soft Condensed Matter Group

  • Sweet Success: Crystal structure of the full-length GLP-1 receptor bound to a peptide agonist

    Sweet Success: Crystal structure of the full-length GLP-1 receptor bound to a peptide agonist Jun 1, 2018

    To design such small molecules, a detailed map of the interactions between GLP-1 and its receptor was needed.

  • Structural insights into the mechanism of bacterial ABC transporters

    Structural insights into the mechanism of bacterial ABC transporters Jun 1, 2018

    Bacteria utilise ATP-binding cassette (ABC) transporters to import nutrients and detoxify themselves. These transporters have been shown to exist ...

  • Structure of the surface layer surrounding Caulobacter crescentus bacteria

    Structure of the surface layer surrounding Caulobacter crescentus bacteria Jun 1, 2018

    Many types of single-celled microorganisms such as bacteria are covered with a protective outer layer of proteins known as the S-layer.

  • How does an inspector call: structures of UGGT, the eukaryotic glycoprotein quality control checkpoint.

    How does an inspector call: structures of UGGT, the eukaryotic glycoprotein quality control checkpoint. Jun 1, 2018

    In all cells derived from animals, plants, fungi and protozoa a single protein called UGGT acts as a quality control checkpoint that inspects ...

  • Insights into the mechanism of colistin resistance from crystal structures of MCR-1

    Insights into the mechanism of colistin resistance from crystal structures of MCR-1 Jun 1, 2018

    Gram-negative bacteria that are extensively resistant to multiple antibiotics are an ever-increasing global threat. Colistin is an antibiotic used ...

  • How human endoglin captures its ligand BMP9

    How human endoglin captures its ligand BMP9 Jun 1, 2018

    Endoglin (ENG)/CD105 is a mammalian glycoprotein that is found in the membranes of cells that line blood vessels. It is essential for healthy ...

Robert Rambo, Science Group Leader

The Soft Condensed Matter (SCM) Group provides the infrared (IR) and Circular Dichroism (CD) microspectroscopy and both Small and Wide Angle X-ray Scattering (SAXS and WAXS) capabilities of Diamond. The group comprises of four beamlines: High Throughput SAXS (B21), the Multimode Infrared Imaging And Microspectroscopy (MIRIAM) beamline (B22), SAXS and Diffraction (I22) and the CD beamline (B23). This unique portfolio of beamlines can analyse a range of samples that include two-dimensional thin films (photovoltaics), living mammalian cells, three-dimensional matrices (e.g. metal-organic frameworks, gels and waxes) and nano-particles in non-crystalline states.

  • Cancer cells hijack human body systems in order to spread

    Cancer cells hijack human body systems in order to spread Aug 9, 2019

    Acute myeloid leukaemia (AML) is a rapid and often fatal disease. The disease originates in the body’s system for producing white blood cells, ...

  • A step towards earlier detection of multiple sclerosis

    A step towards earlier detection of multiple sclerosis Aug 9, 2019

    Using Diamond Light Source’s Small Angle Scattering & Diffraction beamline (I22), I911-SAXS at MAX IV Laboratory, SWING at SOLEIL synchrotron, and ...

  • A novel dynamic flow system for chemical analysis of live biological cells

    A novel dynamic flow system for chemical analysis of live biological cells Aug 9, 2019

    Analysing cells on a cell-by-cell basis using infrared microspectroscopy can reveal important biochemical information, providing insight into ...

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