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  1. Diamond Light Source
  2. News & Literature
  3. Annual Review
  4. Diamond Annual Review 2018
  5. Science Group Updates
  6. Biological Cryo-Imaging Group

Biological Cryo-Imaging Group

  • Sweet Success: Crystal structure of the full-length GLP-1 receptor bound to a peptide agonist

    Sweet Success: Crystal structure of the full-length GLP-1 receptor bound to a peptide agonist Jun 1, 2018

    To design such small molecules, a detailed map of the interactions between GLP-1 and its receptor was needed.

  • Structural insights into the mechanism of bacterial ABC transporters

    Structural insights into the mechanism of bacterial ABC transporters Jun 1, 2018

    Bacteria utilise ATP-binding cassette (ABC) transporters to import nutrients and detoxify themselves. These transporters have been shown to exist ...

  • Structure of the surface layer surrounding Caulobacter crescentus bacteria

    Structure of the surface layer surrounding Caulobacter crescentus bacteria Jun 1, 2018

    Many types of single-celled microorganisms such as bacteria are covered with a protective outer layer of proteins known as the S-layer.

  • How does an inspector call: structures of UGGT, the eukaryotic glycoprotein quality control checkpoint.

    How does an inspector call: structures of UGGT, the eukaryotic glycoprotein quality control checkpoint. Jun 1, 2018

    In all cells derived from animals, plants, fungi and protozoa a single protein called UGGT acts as a quality control checkpoint that inspects ...

  • Insights into the mechanism of colistin resistance from crystal structures of MCR-1

    Insights into the mechanism of colistin resistance from crystal structures of MCR-1 Jun 1, 2018

    Gram-negative bacteria that are extensively resistant to multiple antibiotics are an ever-increasing global threat. Colistin is an antibiotic used ...

  • How human endoglin captures its ligand BMP9

    How human endoglin captures its ligand BMP9 Jun 1, 2018

    Endoglin (ENG)/CD105 is a mammalian glycoprotein that is found in the membranes of cells that line blood vessels. It is essential for healthy ...

Update

Biological imaging at Diamond now has a new home with the recent formation of the Biological Cryo-Imaging Group. This brings together dedicated facilities for X-ray, light and electron microscopy at Diamond. The bending magnet beamline B24 is the source of X-rays for the full field cryo-transmission X-ray microscope dedicated to biological X-ray imaging and the beamline has also established a cryo super resolution fluorescence microscopy facility which is a joint venture between Diamond and the University of Oxford.

The Biological Cryo-Imaging Group is completed with the recently established national centre for cryo-electron microscopy at Diamond, eBIC (Electron Bio-Imaging Centre). Read more ...

  • Red light photosynthesis

    Red light photosynthesis Jun 1, 2018

    The structure of a photosynthetic protein complex that absorbs infrared light in aquatic bacteria has been determined for the first time, using ...

  • How malaria parasites break out of red blood cells during the infection cycle

    How malaria parasites break out of red blood cells during the infection cycle Jun 1, 2018

    Malaria is a highly infectious disease that is widespread in tropical and sub-tropical regions of the world. It is caused by a group of parasitic ...

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