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61 items found for 2025 [total: 509]
Impact of oxidative stress on Magnetospirillum gryphiswaldense MSR-1 physiology and magnetosome biomineralization at the single-cell level Mbio, 27 Dec 2025 DOI: 10.1128/mbio.03265-25
Paclitaxel compromises nuclear integrity in interphase through SUN2-mediated cytoskeletal coupling Journal Of Cell Science, Dec 2025 DOI: 10.1242/jcs.264494
Calicivirus assembly and stability are mediated by the N-terminal domain of the capsid protein with the involvement of the viral genome Plos Pathogens, 21 Dec 2025 DOI: 10.1371/journal.ppat.1013364
Hemoglobin receptor redundancy in Staphylococcus aureus: molecular flexibility as a determinant of divergent hemophore activity Journal Of Structural Biology: X, 12 Dec 2025 DOI: 10.1016/j.yjsbx.2025.100138
RAD51AP1 is a versatile RAD51 modulator Proceedings Of The National Academy Of Sciences, 122 Dec 2025 DOI: 10.1073/pnas.2514728122
Structure and encapsulation of carbonic anhydrase within the α-carboxysome Proceedings Of The National Academy Of Sciences, 122 Nov 2025 DOI: 10.1073/pnas.2523723122
Cryo-EM structure of FcεRI bound IgE reveals multiple defined conformations of the Fab-Fc hinge Allergy, Nov 2025 DOI: 10.1111/all.70132
Journal Paper Krios III-Titan Krios III at Diamond
Using atomic structures of extremophilic ribosomes to study bacterial adaptation to stress Nov 2025
Thesis Krios I-Titan Krios I at Diamond
Ancestral chaperonins provide the first structural glimpse into early multimeric protein evolution Molecular Biology And Evolution, Nov 2025 DOI: 10.1093/molbev/msaf314
The architecture of membrane structures involved in hepatitis C virus genome replication revealed under close-to-native conditions by cryo-electron tomography Journal Of General Virology, 106 Nov 2025 DOI: 10.1099/jgv.0.002168
Aviadenovirus structure: A highly thermostable capsid in the absence of stabilizing proteins Plos Pathogens, 21 Oct 2025 DOI: 10.1371/journal.ppat.1013553
Rational crystal contact engineering for programmable self-assembled protein architectures Angewandte Chemie International Edition, 8 Oct 2025 DOI: 10.1002/anie.202516635
Journal Paper Krios IV-Titan Krios IV at Diamond
Structural basis of multitasking by the apicoplast DNA polymerase from Plasmodium falciparum Nucleic Acids Research, 53 Oct 2025 DOI: 10.1093/nar/gkaf1005
Locating the missing chlorophylls f in far-red photosystem I Science, Oct 2025 DOI: 10.1126/science.ado6830
Journal Paper Krios III-Titan Krios III at Diamond
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail Science Advances, 11 Oct 2025 DOI: 10.1126/sciadv.adx1178
Structural basis of T-loop-independent recognition and activation of CDKs by the CDK-activating kinase Science, Oct 2025 DOI: 10.1126/science.adw0053
Journal Paper Krios I-Titan Krios I at Diamond Krios II-Titan Krios II at Diamond Krios III-Titan Krios III at Diamond
A binding site for the antibiotic GE81112 in the ribosomal mRNA channel Mbio, Oct 2025 DOI: 10.1128/mbio.03978-24
Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging Nature Communications, 16 Sept 2025 DOI: 10.1038/s41467-025-63363-9
Elucidating the structure and assembly mechanism of actinoporin pores in complex membrane environments Science Advances, 11 Sept 2025 DOI: 10.1126/sciadv.adv0683
Coming clean and avoiding bubble trouble - using detergents wisely in the purification of membrane proteins for Cryo-EM studies Biomolecules, 15 Sept 2025 DOI: 10.3390/biom15091315
Journal Paper Krios I-Titan Krios I at Diamond Krios II-Titan Krios II at Diamond Krios III-Titan Krios III at Diamond Krios IV-Titan Krios IV at Diamond Krios V-Titan Krios V at Diamond open access
Resistance to CDK7 inhibitors directed by acquired mutation of a conserved residue in cancer cells The Embo Journal, 74 Sept 2025 DOI: 10.1038/s44318-025-00554-6
Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers Nature Structural & Molecular Biology, 32 Sept 2025 DOI: 10.1038/s41594-025-01665-8
Structural analysis of the NifL ‐ NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii The Febs Journal, 93 Sept 2025 DOI: 10.1111/febs.70253
Collagen VI microfibril structure reveals mechanism for molecular assembly and clustering of inherited pathogenic mutations Nature Communications, 16 Aug 2025 DOI: 10.1038/s41467-025-62923-3
In-cell structure and variability of pyrenoid Rubisco Nature Communications, 16 Aug 2025 DOI: 10.1038/s41467-025-62998-y
Direct visualization of HIV-1 core nuclear import and its interplay with the nuclear pore Embo Reports, 485 Aug 2025 DOI: 10.1038/s44319-025-00567-6
Covalently constrained 'Di-Gembodies' enable parallel structure solutions by cryo-EM Nature Chemical Biology, 52 Aug 2025 DOI: 10.1038/s41589-025-01972-7
HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability Nature Microbiology, 233 Jul 2025 DOI: 10.1038/s41564-025-02054-z
Unveiling the structural spectrum of SARS-CoV-2 fusion by in situ cryo-ET Nature Communications, 16 June 2025 DOI: 10.1038/s41467-025-60406-z
Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions Nature Communications, 16 June 2025 DOI: 10.1038/s41467-025-60536-4
Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states Cell Reports, 44 May 2025 DOI: 10.1016/j.celrep.2025.115581
Cryo-EM Structure of the relaxosome, a complex essential for bacterial mating and the spread of antibiotic resistance genes Nature Communications, 16 May 2025 DOI: 10.1038/s41467-025-60116-6
Structural maturation of the matrix lattice is not required for HIV-1 particle infectivity Science Advances, 11 May 2025 DOI: 10.1126/sciadv.adv4356
PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor Proceedings Of The National Academy Of Sciences, 122 Apr 2025 DOI: 10.1073/pnas.2417218122
Structural insight into a human H ferritin@gold-monocarbene adduct: aurophilicity revealed in a biological context Angewandte Chemie International Edition, Apr 2025 DOI: 10.1002/anie.202503778
Journal Paper Krios IV-Titan Krios IV at Diamond
Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment Nature Communications, 16 Apr 2025 DOI: 10.1038/s41467-025-58350-z
Transport of phenoxyacetic acid herbicides by PIN-FORMED auxin transporters Nature Plants, 115 Apr 2025 DOI: 10.1038/s41477-025-01984-0
Cryo-EM structure of the conjugation H-pilus reveals the cyclic nature of the TrhA pilin Proceedings Of The National Academy Of Sciences, 122 Apr 2025 DOI: 10.1073/pnas.2427228122
Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology Science, 388 Apr 2025 DOI: 10.1126/science.adp2433
Journal Paper Krios I-Titan Krios I at Diamond Krios III-Titan Krios III at Diamond Krios IV-Titan Krios IV at Diamond
Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213 Nature Structural & Molecular Biology, 62 Apr 2025 DOI: 10.1038/s41594-025-01530-8
Subunit specialization in AAA+ proteins and substrate unfolding during transcription complex remodeling Proceedings Of The National Academy Of Sciences, 122 Apr 2025 DOI: 10.1073/pnas.2425868122
Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis Nature Communications, 16 Apr 2025 DOI: 10.1038/s41467-025-58902-3
Cotadutide reversible self-assembly based long-acting injectable depot for sustained delivery of GLP-1 glucagon receptor agonists with controlled burst release Journal Of Controlled Release, 380 Apr 2025 DOI: 10.1016/j.jconrel.2025.01.064
Journal Paper Krios V-Titan Krios V at Diamond
Penton blooming, a conserved mechanism of genome delivery used by disparate microviruses Mbio, Mar 2025 DOI: 10.1128/mbio.03713-24
Production of an immunogenic trivalent poliovirus virus-like particle vaccine candidate in yeast using controlled fermentation Npj Vaccines, 10 Mar 2025 DOI: 10.1038/s41541-025-01111-2
Stepwise recruitment of chaperone Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibril disassembly Communications Biology, 8 Mar 2025 DOI: 10.1038/s42003-025-07906-2
Structure and regulatory mechanism of human uncoupling protein 1 Mar 2025 DOI: 10.17863/CAM.116448
Thesis Krios I-Titan Krios I at Diamond
Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland Elife, 13 Mar 2025 DOI: 10.7554/eLife.103492
Molecular mechanism of bacteriophage contraction structure of an S-layer–penetrating bacteriophage Life Science Alliance, 8 Mar 2025 DOI: 10.26508/lsa.202403088
Cryo-EM structures of a protein pore reveal a cluster of cholesterol molecules and diverse roles of membrane lipids Nature Communications, 16 Mar 2025 DOI: 10.1038/s41467-025-58334-z
Cryo-EM structures of apo and atorvastatin-bound human 3-hydroxy-3-methylglutaryl-coenzyme A reductase Acta Crystallographica Section F Structural Biology Communications, 81 Mar 2025 DOI: 10.1107/S2053230X25001098
Proton conductance by human uncoupling protein 1 is inhibited by purine and pyrimidine nucleotides The Embo Journal, 630 Feb 2025 DOI: 10.1038/s44318-025-00395-3
The structure of the R2T complex reveals a different architecture from the related HSP90 cochaperone R2TP Structure, 18 Feb 2025 DOI: 10.1016/j.str.2025.01.023
Journal Paper Krios III-Titan Krios III at Diamond
Structural basis for lipid-mediated activation of G protein-coupled receptor GPR55 Nature Communications, 16 Feb 2025 DOI: 10.1038/s41467-025-57204-y
Cryo-EM structure and evolutionary history of the conjugation surface exclusion protein TraT Nature Communications, 16 Jan 2025 DOI: 10.1038/s41467-025-55834-w
Jigsaw puzzle: Deciphering the chloroplast transcription machinery Jan 2025
Science Highlight Krios II-Titan Krios II at Diamond Krios IV-Titan Krios IV at Diamond
Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2 Nature Communications, 16 Jan 2025 DOI: 10.1038/s41467-025-55942-7
Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines Nature Communications, 16 Jan 2025 DOI: 10.1038/s41467-025-56118-z
The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix Matrix Biology, 57 Jan 2025 DOI: 10.1016/j.matbio.2025.01.002
Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) Krios IV-Titan Krios IV at Diamond open access
Structure of WzxE the lipid III flippase for Enterobacterial Common Antigen polysaccharide Open Biology, 15 Jan 2025 DOI: 10.1098/rsob.240310
Journal Paper I03-Macromolecular Crystallography I23-Long wavelength MX I24-Microfocus Macromolecular Crystallography Krios II-Titan Krios II at Diamond open access
Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament Nature Communications, 16 Jan 2025 DOI: 10.1038/s41467-025-56127-y
- Marta Maso-Martinez, Julika Radecke, Craig Macgregor-Chatwin, Paul D. Topham, Alfred Fernandez-Castane, "Impact of oxidative stress on Magnetospirillum gryphiswaldense MSR-1 physiology and magnetosome biomineralization at the single-cell level", Mbio, 27 (2025), DOI: 10.1128/mbio.03265-25
- Thomas Hale, Victoria L. Hale, Piotr Kolata, Ália Dos Santos, Matteo Allegretti, "Paclitaxel compromises nuclear integrity in interphase through SUN2-mediated cytoskeletal coupling", Journal Of Cell Science (2025), DOI: 10.1242/jcs.264494
- Guy Novoa, Carlos P. Mata, Johann Mertens, María Zamora-Ceballos, Juan M. Martínez-Romero, Juan Fontana, José L. Carrascosa, Juan Bárcena, Jose R. Caston, "Calicivirus assembly and stability are mediated by the N-terminal domain of the capsid protein with the involvement of the viral genome", Plos Pathogens, 21 (2025), DOI: 10.1371/journal.ppat.1013364
- Valeria Buoli Comani, Omar De Bei, Francesca Pancrazi, Marcos Gragera, Giulia Paris, Marialaura Marchetti, Barbara Campanini, Luca Ronda, Ben F. Luisi, Serena Faggiano, Anna Rita Bizzarri, Stefano Bettati, "Hemoglobin receptor redundancy in Staphylococcus aureus: molecular flexibility as a determinant of divergent hemophore activity", Journal Of Structural Biology: X, 12 (2025), DOI: 10.1016/j.yjsbx.2025.100138
- Lucas Kuhlen, Bilge Argunhan, Pengtao Liang, Janet Zhong, Laura Masino, Xiaodong Zhang, "RAD51AP1 is a versatile RAD51 modulator", Proceedings Of The National Academy Of Sciences, 122 (2025), DOI: 10.1073/pnas.2514728122
- Pei Cing Ng, Oluwatobi Adegbite, Tianpei Li, Arnaud Basle, Jon Marles-Wright, Lu-Ning Liu, "Structure and encapsulation of carbonic anhydrase within the α-carboxysome", Proceedings Of The National Academy Of Sciences, 122 (2025), DOI: 10.1073/pnas.2523723122
- Rasmus K. Jensen, Michaela Miehe, Rosaria Gandini, Martin H. Jørgensen, Edzard Spillner, Gregers R. Andersen, "Cryo-EM structure of FcεRI bound IgE reveals multiple defined conformations of the Fab-Fc hinge", Allergy (2025), DOI: 10.1111/all.70132
- [Thesis] Karla Helena-Bueno, "Using atomic structures of extremophilic ribosomes to study bacterial adaptation to stress" (2025)
- Rita Severino, Jorge Cuellar, Jorge Gutiérrez-Seijo, Moisés Maestro-López, Luis Sánchez-Pulido, César Santiago, Mercedes Moreno-Paz, José Maria Valpuesta, Víctor Parro, "Ancestral chaperonins provide the first structural glimpse into early multimeric protein evolution", Molecular Biology And Evolution (2025), DOI: 10.1093/molbev/msaf314
- Upasana M. Sykora, Thomas J. O'Sullivan, Juan Fontana, Mark Harris, "The architecture of membrane structures involved in hepatitis C virus genome replication revealed under close-to-native conditions by cryo-electron tomography", Journal Of General Virology, 106 (2025), DOI: 10.1099/jgv.0.002168
- Marta Perez-Illana, Anna Schachner, Mercedes Hernando-Perez, Gabriela N. Condezo, Alberto Paradela, Marta Martínez, Roberto Marabini, Michael Hess, Carmen San Martín, "Aviadenovirus structure: A highly thermostable capsid in the absence of stabilizing proteins", Plos Pathogens, 21 (2025), DOI: 10.1371/journal.ppat.1013553
- Mantas Liutkus, Adriana L. Rojas, Aitziber L. Cortajarena, "Rational crystal contact engineering for programmable self-assembled protein architectures", Angewandte Chemie International Edition, 8 (2025), DOI: 10.1002/anie.202516635
- Anamika Kumari, Theodora Enache, Timothy D. Craggs, Janice D. Pata, Indrajit Lahiri, "Structural basis of multitasking by the apicoplast DNA polymerase from Plasmodium falciparum", Nucleic Acids Research, 53 (2025), DOI: 10.1093/nar/gkaf1005
- Giovanni Consoli, Fiazall Tufail, Ho Fong Leong, Stefania Viola, Geoffry A. Davis, Nicholas Rew, Daniel Medranda, Michael Hofer, Paul Simpson, Marco Sandrin, Benoit Chachuat, Jenny Nelson, Thomas Renger, James W. Murray, Andrea Fantuzzi, A. William Rutherford, "Locating the missing chlorophylls f in far-red photosystem I", Science (2025), DOI: 10.1126/science.ado6830
- Daniel X. Zhang, Michail N. Isupov, Rebecca M. Davies, Sabine Schwarzer, Mathew Mclaren, William S Stuart, Vicki A. M. Gold, Hanna M. Oksanen, Tessa E. F. Quax, Bertram Daum, "Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail", Science Advances, 11 (2025), DOI: 10.1126/sciadv.adx1178
- Victoria I. Cushing, Amy J. S. Mcgeoch, Sophie L. Williams, Theodoros I. Roumeliotis, Junjie Feng, Lucy M. Dan, Jyoti S. Choudhary, Norman E. Davey, Basil J. Greber, "Structural basis of T-loop-independent recognition and activation of CDKs by the CDK-activating kinase", Science (2025), DOI: 10.1126/science.adw0053
- Andreas Schedlbauer, Xu Han, Wouter Van Bakel, Tatsuya Kaminishi, Borja Ochoa-Lizarralde, Idoia Iturrioz, Retina Çapuni, Ransford Parry, Ronny Zegarra, David Gil-Carton, Jorge P. López-Alonso, Kristina Barragan Sanz, Letizia Brandi, Claudio O. Gualerzi, Paola Fucini, Sean R. Connell, "A binding site for the antibiotic GE81112 in the ribosomal mRNA channel", Mbio (2025), DOI: 10.1128/mbio.03978-24
- Yanan Zhu, Alex B. Kleinpeter, Juan S. Rey, Juan Shen, Yao Shen, Jialu Xu, Nathan Hardenbrook, Long Chen, Anka Lucic, Juan R. Perilla, Eric O. Freed, Peijun Zhang, "Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-63363-9
- Rocio Arranz, César Santiago, Simonas Masiulis, Esperanza Rivera-De-Torre, Juan Palacios-Ortega, Diego Carlero, Diego Heras-Márquez, José G. Gavilanes, Ernesto Arias-Palomo, Álvaro Martínez-Del-Pozo, Sara García-Linares, Jaime Martin-Benito, "Elucidating the structure and assembly mechanism of actinoporin pores in complex membrane environments", Science Advances, 11 (2025), DOI: 10.1126/sciadv.adv0683
- Bowen Chen, Peter Harrison, Vasileios Kargas, Naomi Pollock, Robert C. Ford, Stephen M. Prince, Richard F. Collins, "Coming clean and avoiding bubble trouble - using detergents wisely in the purification of membrane proteins for Cryo-EM studies", Biomolecules, 15 (2025), DOI: 10.3390/biom15091315
- Chun-Fui Lai, Victoria I. Cushing, Ellen Olden, Charlotte L Bevan, R. Charles Coombes, Basil J. Greber, Laki Buluwela, Simak Ali, "Resistance to CDK7 inhibitors directed by acquired mutation of a conserved residue in cancer cells", The Embo Journal, 74 (2025), DOI: 10.1038/s44318-025-00554-6
- Tianyang Liu, Luyan Cao, Miroslav Mladenov, Guillaume Romet-Lemonne, Michael Way, Carolyn A. Moores, "Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers", Nature Structural & Molecular Biology, 32 (2025), DOI: 10.1038/s41594-025-01665-8
- Marcelo Bueno Batista, Jake Richardson, Michael W. Webster, Dmitry Ghilarov, John W. Peters, David M. Lawson, Ray Dixon, "Structural analysis of the NifL ‐ NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii", The Febs Journal, 93 (2025), DOI: 10.1111/febs.70253
- Alan R. F. Godwin, Mark H. Becker, Rana Dajani, Matthew Snee, Alan M. Roseman, Clair Baldock, "Collagen VI microfibril structure reveals mechanism for molecular assembly and clustering of inherited pathogenic mutations", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-62923-3
- Nadav Elad, Zhen Hou, Maud Dumoux, Alireza Ramezani, Juan R. Perilla, Peijun Zhang, "In-cell structure and variability of pyrenoid Rubisco", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-62998-y
- Zhen Hou, Stanley Fronik, Yao Shen, Long Chen, Christopher Thompson, Sarah Neumann, Peijun Zhang, "Direct visualization of HIV-1 core nuclear import and its interplay with the nuclear pore", Embo Reports, 485 (2025), DOI: 10.1038/s44319-025-00567-6
- Gangshun Yi, Dimitrios Mamalis, Mingda Ye, Loic Carrique, Michael Fairhead, Huanyu Li, Katharina L. Duerr, Peijun Zhang, David B. Sauer, Frank Von Delft, Benjamin G. Davis, Robert J. C. Gilbert, "Covalently constrained 'Di-Gembodies' enable parallel structure solutions by cryo-EM", Nature Chemical Biology, 52 (2025), DOI: 10.1038/s41589-025-01972-7
- Zhen Hou, Yao Shen, Stanley Fronik, Juan Shen, Jiong Shi, Jialu Xu, Long Chen, Nathan Hardenbrook, Alan N. Engelman, Christopher Aiken, Peijun Zhang, "HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability", Nature Microbiology, 233 (2025), DOI: 10.1038/s41564-025-02054-z
- Caner Akil, Jialu Xu, Juan Shen, Peijun Zhang, "Unveiling the structural spectrum of SARS-CoV-2 fusion by in situ cryo-ET", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-60406-z
- Alicia Santos-Aledo, Adrián Plaza-Pegueroles, Marta Sanz-Murillo, Federico M. Ruiz, Peini Hou, Jun Xu, David Gil-Carton, Dong Wang, Carlos Fernandez-Tornero, "Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-60536-4
- Anna Li, Ashley C. W. Pike, Richard Webster, Susan Maxwell, Wei-Wei Liu, Gamma Chi, Jacqueline Palace, David Beeson, David B. Sauer, Yin Yao Dong, "Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states", Cell Reports, 44 (2025), DOI: 10.1016/j.celrep.2025.115581
- Sunanda M. Williams, Sandra Raffl, Sabine Kienesberger, Aravindan Ilangovan, Ellen L. Zechner, Gabriel Waksman, "Cryo-EM Structure of the relaxosome, a complex essential for bacterial mating and the spread of antibiotic resistance genes", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-60116-6
- Long Chen, Yuta Hikichi, Juan S. Rey, Caner Akil, Yanan Zhu, Hana Veler, Yao Shen, Juan R. Perilla, Eric O. Freed, Peijun Zhang, "Structural maturation of the matrix lattice is not required for HIV-1 particle infectivity", Science Advances, 11 (2025), DOI: 10.1126/sciadv.adv4356
- Tarik Husremović, Vanessa Meier, Lucas Piëch, Katharina M. Siess, Sumire Antonioli, Irina Grishkovskaya, Nikoleta Kircheva, Silvia E. Angelova, Karoline Wenzl, Andreas Brandstätter, Jiri Veis, Fran Miočić-Stošić, Dorothea Anrather, Markus Hartl, Linda Truebestein, Luis M. Cerron-Alvan, Martin Leeb, Bojan Žagrović, Stephan Hann, Christoph Bock, Egon Ogris, Todor Dudev, Nicholas A. T. Irwin, David Haselbach, Thomas A. Leonard, "PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor", Proceedings Of The National Academy Of Sciences, 122 (2025), DOI: 10.1073/pnas.2417218122
- Lucrezia Cosottini, Andrea Giachetti, Annalisa Guerri, Ane Martinez-Castillo, Andrea Geri, Stefano Zineddu, Nicola G. A. Abrescia, Luigi Messori, Paola Turano, Antonio Rosato, "Structural insight into a human H ferritin@gold-monocarbene adduct: aurophilicity revealed in a biological context", Angewandte Chemie International Edition (2025), DOI: 10.1002/anie.202503778
- Zhuoyao Chen, Gamma Chi, Timea Balo, Xiangrong Chen, Beatriz Ralsi Montes, Steven C. Clifford, Vincenzo D'Angiolella, Timea Szabo, Arpad Kiss, Tibor Novak, András Herner, András Kotschy, Alex N. Bullock, "Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-58350-z
- Lukas Schulz, Kien Lam Ung, Lorena Zuzic, Sarah Koutnik-Abele, Birgit Schiøtt, David L. Stokes, Bjørn Panyella Pedersen, Ulrich Z. Hammes, "Transport of phenoxyacetic acid herbicides by PIN-FORMED auxin transporters", Nature Plants, 115 (2025), DOI: 10.1038/s41477-025-01984-0
- Naito Ishimoto, Joshua L. C. Wong, Shan He, Sally Shirran, Olivia Wright-Paramio, Chloe Seddon, Nanki Singh, Carlos Balsalobre, Ravi R. Sonani, Abigail Clements, Edward H. Egelmane, Gad Frankel, Konstantinos Beis, "Cryo-EM structure of the conjugation H-pilus reveals the cyclic nature of the TrhA pilin", Proceedings Of The National Academy Of Sciences, 122 (2025), DOI: 10.1073/pnas.2427228122
- Nattapong Sanguankiattichai, Balakumaran Chandrasekar, Yuewen Sheng, Nathan Hardenbrook, Werner W. A. Tabak, Margit Drapal, Farnusch Kaschani, Clemens Grünwald-Gruber, Daniel Krahn, Pierre Buscaill, Suzuka Yamamoto, Atsushi Kato, Robert Nash, George Fleet, Richard Strasser, Paul D. Fraser, Markus Kaiser, Peijun Zhang, Gail M. Preston, Renier A. L. Van Der Hoorn, "Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology", Science, 388, 297 - 303 (2025), DOI: 10.1126/science.adp2433
- Katerina Naydenova, Keith B. Boyle, Claudio Pathe, Prathyush Pothukuchi, Ana Crespillo-Casado, Felix Scharte, Pierre-Mehdi Hammoudi, Elsje G. Otten, Neal M. Alto, Felix Randow, "Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213", Nature Structural & Molecular Biology, 62 (2025), DOI: 10.1038/s41594-025-01530-8
- Forson Gao, Fuzhou Ye, Martin Buck, Xiaodong Zhang, "Subunit specialization in AAA+ proteins and substrate unfolding during transcription complex remodeling", Proceedings Of The National Academy Of Sciences, 122 (2025), DOI: 10.1073/pnas.2425868122
- Adrián González-López, Xueliang Ge, Daniel S. D. Larsson, Carina Sihlbom Wallem, Suparna Sanyal, Maria Selmer, "Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-58902-3
- Bin Yang, Durga Devalla, Silvia Sonzini, Mikael Boberg, Sashi Gopaul, Monika Sundqvist, Iain Grant, Christopher Jones, Stephanie Brookes, Cindy Weidauer, Eleonora Paladino, Najet Mahmoudi, Jason Van Rooyen, Ana Gomes Dos Santos, Johanna Laru, Andy Campbell, Lutz Jermutus, Annette Bak, "Cotadutide reversible self-assembly based long-acting injectable depot for sustained delivery of GLP-1 glucagon receptor agonists with controlled burst release", Journal Of Controlled Release, 380, 647 - 663 (2025), DOI: 10.1016/j.jconrel.2025.01.064
- Pavol Bardy, Conor I. W. Macdonald, Paul C. Kirchberger, Huw T. Jenkins, Tibor Botka, Lewis Byrom, Nawshin T. B. Alim, Daouda A. K. Traore, Hannah C. Koenig, Tristan R. Nicholas, Maria Chechik, Samuel J. Hart, Johan P. Turkenburg, James N. Blaza, J. Thomas Beatty, Paul C. M. Fogg, Alfred A. Antson, "Penton blooming, a conserved mechanism of genome delivery used by disparate microviruses", Mbio (2025), DOI: 10.1128/mbio.03713-24
- Lee Sherry, Keith Grehan, Mohammad W. Bahar, Jessica J. Swanson, Helen Fox, Sue Matthews, Sarah Carlyle, Ling Qin, Claudine Porta, Steven Wilkinson, Suzanne Robb, Naomi Clark, John Liddell, Elizabeth E. Fry, David I. Stuart, Andrew J. Macadam, David J. Rowlands, Nicola J. Stonehouse, "Production of an immunogenic trivalent poliovirus virus-like particle vaccine candidate in yeast using controlled fermentation", Npj Vaccines, 10 (2025), DOI: 10.1038/s41541-025-01111-2
- Jim Monistrol, Joseph G. Beton, Erin C. Johnston, Thi Lieu Dang, Bernd Bukau, Helen R. Saibil, "Stepwise recruitment of chaperone Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibril disassembly", Communications Biology, 8 (2025), DOI: 10.1038/s42003-025-07906-2
- [Thesis] Scott Jones, "Structure and regulatory mechanism of human uncoupling protein 1" (2025), DOI: 10.17863/CAM.116448
- Gabriel Magno De Freitas Almeida, Iker Arriaga, Bruna Luiza De Azevedo, Miika Leppänen, Jonatas S. Abrahão, Julien Andreani, Davide Zabeo, Janne J. Ravantti, Nicola G. A. Abrescia, Lotta-Riina Sundberg, "Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland", Elife, 13 (2025), DOI: 10.7554/eLife.103492
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- Manikandan Karuppasamy, Jason Van Rooyen, "Cryo-EM structures of apo and atorvastatin-bound human 3-hydroxy-3-methylglutaryl-coenzyme A reductase", Acta Crystallographica Section F Structural Biology Communications, 81 (2025), DOI: 10.1107/S2053230X25001098
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- Alberto Palacios-Abella, Andres Lopez-Perrote, Jasminka Boskovic, Sandra Fonseca, Cristina Úrbez, Vicente Rubio, Oscar Llorca, David Alabadí, "The structure of the R2T complex reveals a different architecture from the related HSP90 cochaperone R2TP", Structure, 18 (2025), DOI: 10.1016/j.str.2025.01.023
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- Chloe Seddon, Sophia David, Joshua L. C. Wong, Naito Ishimoto, Shan He, Jonathan Bradshaw, Wen Wen Low, Gad Frankel, Konstantinos Beis, "Cryo-EM structure and evolutionary history of the conjugation surface exclusion protein TraT", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-55834-w
- [Science Highlight] Diamond Light Source, "Jigsaw puzzle: Deciphering the chloroplast transcription machinery" (2025)
- Huanyu Z. Li, Ashley C. Pike, Yung-Ning Chang, Dheeraj Prakaash, Zuzana Gelova, Josefina Stanka, Christophe Moreau, Hannah C. Scott, Frank Wunder, Gernot Wolf, Andreea Scacioc, Gavin Mckinley, Helena Batoulis, Shubhashish Mukhopadhyay, Andrea Garofoli, Adán Pinto-Fernández, Benedikt M. Kessler, Nicola A. Burgess-Brown, Saša Štefanić, Tabea Wiedmer, Katharina L. Duerr, Vera Puetter, Alexander Ehrmann, Syma Khalid, Alvaro Ingles-Prieto, Giulio Superti-Furga, David B. Sauer, "Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-55942-7
- Lee Sherry, Mohammad W. Bahar, Claudine Porta, Helen Fox, Keith Grehan, Veronica Nasta, Helen M. E. Duyvesteyn, Luigi De Colibus, Johanna Marsian, Inga Murdoch, Daniel Ponndorf, Seong-Ryong Kim, Sachin Shah, Sarah Carlyle, Jessica J. Swanson, Sue Matthews, Clare Nicol, George P. Lomonossoff, Andrew J. Macadam, Elizabeth E. Fry, David I. Stuart, Nicola J. Stonehouse, David J. Rowlands, "Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-56118-z
- Anokhi Shah, Xiaoli Zhang, Matthew Snee, Michael P. Lockhart-Cairns, Colin W. Levy, Thomas A. Jowitt, Holly L. Birchenough, Louisa Dean, Richard Collins, Rebecca J. Dodd, Abigail R. E. Roberts, Jan J. Enghild, Alberto Mantovani, Juan Fontana, Clair Baldock, Antonio Inforzato, Ralf P. Richter, Anthony J. Day, "The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix", Matrix Biology, 57 (2025), DOI: 10.1016/j.matbio.2025.01.002
- Audrey Le Bas, Bradley R. Clarke, Tanisha Teelucksingh, Micah Lee, Kamel El Omari, Andrew M. Giltrap, Stephen A. Mcmahon, Hui Liu, John H. Beale, Vitaliy Mykhaylyk, Ramona Duman, Neil G. Paterson, Philip N. Ward, Peter J. Harrison, Miriam Weckener, Els Pardon, Jan Steyaert, Huanting Liu, Andrew Quigley, Benjamin G. Davis, Armin Wagner, Chris Whitfield, James H. Naismith, "Structure of WzxE the lipid III flippase for Enterobacterial Common Antigen polysaccharide", Open Biology, 15 (2025), DOI: 10.1098/rsob.240310
- Emmajay Sutherland, Christopher J. Harding, Tancrède Du Monceau De Bergendal, Gordon J. Florence, Katrin Ackermann, Bela E. Bode, Silvia Synowsky, Ramasubramanian Sundaramoorthy, Clarissa Melo Czekster, "Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament", Nature Communications, 16 (2025), DOI: 10.1038/s41467-025-56127-y
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