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58 items found for 2024 [total: 509]
Rubisco packaging and stoichiometric composition of the native β-carboxysome in Synechococcus elongatus PCC7942 Plant Physiology, Dec 2024 DOI: 10.1093/plphys/kiae665
Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM Nature Communications, 15 Dec 2024 DOI: 10.1038/s41467-024-53745-w
Journal Paper Krios I-Titan Krios I at Diamond Krios II-Titan Krios II at Diamond Krios IV-Titan Krios IV at Diamond open access
Towards a molecular picture of the archaeal cell surface Nature Communications, 15 Dec 2024 DOI: 10.1038/s41467-024-53986-9
Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin Science, Dec 2024 DOI: 10.1126/science.adr7920
Journal Paper Krios I-Titan Krios I at Diamond
Engineering CO2-fixing modules in E. coli via efficient assembly of cyanobacterial Rubisco and carboxysomes Plant Communications, Dec 2024 DOI: 10.1016/j.xplc.2024.101217
Mechanism for Vipp1 spiral formation, ring biogenesis, and membrane repair Nature Structural & Molecular Biology, 184 Nov 2024 DOI: 10.1038/s41594-024-01401-8
The role of macromolecular condensates in the regulation of intracellular calcium transport for coccolith formation Advanced Functional Materials, 41 Nov 2024 DOI: 10.1002/adfm.202415344
Nucleosome flipping drives kinetic proofreading and processivity by SWR1 Nature, 12 Nov 2024 DOI: 10.1038/s41586-024-08152-y
The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment Embo Reports, 18 Nov 2024 DOI: 10.1038/s44319-024-00306-3
Structural characterisation of a phage-like bacteriocin from Pseudomonas sp. by cryo-Electron Microscopy Oct 2024 DOI: 10.1051/bioconf/202412921010
Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213 Embo Reports, 74 Oct 2024 DOI: 10.1038/s44319-024-00280-w
Mechanism of degrader-targeted protein ubiquitinability Science Advances, 10 Oct 2024 DOI: 10.1126/sciadv.ado6492
Structure of the turnover-ready state of an ancestral respiratory complex I Nature Communications, 15 Oct 2024 DOI: 10.1038/s41467-024-53679-3
Adaptive multi-epitope targeting and avidity-enhanced nanobody platform for ultrapotent, durable antiviral therapy Cell, 19 Oct 2024 DOI: 10.1016/j.cell.2024.09.043
CDK5RAP2 activates microtubule nucleator γTuRC by facilitating template formation and actin release Developmental Cell, 28 Sept 2024 DOI: 10.1016/j.devcel.2024.09.001
Journal Paper Krios III-Titan Krios III at Diamond
Intracellular morphogenesis of diatom silica is guided by local variations in membrane curvature Nature Communications, 15 Sept 2024 DOI: 10.1038/s41467-024-52211-x
Stabilization of the hexasome intermediate during histone exchange by yeast SWR1 complex Molecular Cell, 12 Sept 2024 DOI: 10.1016/j.molcel.2024.08.015
Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis Oncogene, 23 Sept 2024 DOI: 10.1038/s41388-024-03137-7
A monoclonal antibody targeting the Nipah virus fusion glycoprotein apex imparts protection from disease Journal Of Virology, Sept 2024 DOI: 10.1128/jvi.00638-24
Journal Paper Krios I-Titan Krios I at Diamond
Development of a two-component nanoparticle vaccine displaying an HIV-1 envelope glycoprotein that elicits tier 2 neutralising antibodies Vaccines, 12 Sept 2024 DOI: 10.3390/vaccines12091063
Bidirectional pilus processing in the Tad pilus system motor CpaF Nature Communications, 15 Aug 2024 DOI: 10.1038/s41467-024-50280-6
Cryo-EM structure of the CDK2-cyclin A-CDC25A complex Nature Communications, 15 Aug 2024 DOI: 10.1038/s41467-024-51135-w
Structural insights into Frizzled3 through nanobody modulators Nature Communications, 15 Aug 2024 DOI: 10.1038/s41467-024-51451-1
Structural and biochemical insights into the mechanism of action of the clinical USP1 inhibitor, KSQ-4279 Journal Of Medicinal Chemistry, Aug 2024 DOI: 10.1021/acs.jmedchem.4c01184
Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs Nature Structural & Molecular Biology, 20 Jul 2024 DOI: 10.1038/s41594-024-01357-9
Structure of the bacteriophage PhiKZ non-virion RNA polymerase transcribing from its promoter p119L Journal Of Molecular Biology, 15 Jul 2024 DOI: 10.1016/j.jmb.2024.168713
CryoET reveals actin filaments within platelet microtubules Nature Communications, 15 Jul 2024 DOI: 10.1038/s41467-024-50424-8
FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions Nature, 90 Jul 2024 DOI: 10.1038/s41586-024-07770-w
A first peek at a "crass" virus Jul 2024
Science Highlight Krios I-Titan Krios I at Diamond
Molecular plasticity of herpesvirus nuclear egress analysed in situ Nature Microbiology, 9 Jul 2024 DOI: 10.1038/s41564-024-01716-8
Journal Paper Scios-Scios at Diamond
Cryo-tomography and 3D electron diffraction reveal the polar habit and chiral structure of the malaria pigment crystal hemozoin Acs Central Science, Jul 2024 DOI: 10.1021/acscentsci.4c00162
Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria Nature Chemistry, 399 June 2024 DOI: 10.1038/s41557-024-01516-x
Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I Science, 384 June 2024 DOI: 10.1126/science.ado2075
Journal Paper Krios II-Titan Krios II at Diamond
CryoEM reveals the structure of an archaeal pilus involved in twitching motility Nature Communications, 15 June 2024 DOI: 10.1038/s41467-024-45831-w
Molecular basis for transposase activation by a dedicated AAA+ ATPase Nature, 630 June 2024 DOI: 10.1038/s41586-024-07550-6
Journal Paper Krios I-Titan Krios I at Diamond Krios II-Titan Krios II at Diamond Krios IV-Titan Krios IV at Diamond open access
Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2 Nature Communications, 15 June 2024 DOI: 10.1038/s41467-024-48921-x
Development of focused ultrasound-assisted nanoplexes for RNA delivery Nanomaterials, 14 June 2024 DOI: 10.3390/nano14131089
Distance tuneable integral membrane protein containing floating bilayers via in situ directed self-assembly Nanoscale, 277 June 2024 DOI: 10.1039/D3NR04622B
Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist Structure, 594 May 2024 DOI: 10.1016/j.str.2024.05.005
Understanding a protein that fuels bowel cancer May 2024
Science Highlight Krios I-Titan Krios I at Diamond Krios II-Titan Krios II at Diamond Krios III-Titan Krios III at Diamond
Structural and molecular mechanisms af ATP-dependent DNA transposition using IS21 as a model system May 2024
Thesis Krios I-Titan Krios I at Diamond
EMinsight : a tool to capture cryoEM microscope configuration and experimental outcomes for analysis and deposition Acta Crystallographica Section D Structural Biology, 80 Apr 2024 DOI: 10.1107/S2059798324001578
Journal Paper Krios II-Titan Krios II at Diamond Krios III-Titan Krios III at Diamond Krios IV-Titan Krios IV at Diamond open access
The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili Nature Communications, 15 Apr 2024 DOI: 10.1038/s41467-024-47212-9
Architecture and regulation of filamentous human cystathionine beta-synthase Nature Communications, 15 Apr 2024 DOI: 10.1038/s41467-024-46864-x
Conformational changes in the Niemann–Pick type C1 protein NCR1 drive sterol translocation Proceedings Of The National Academy Of Sciences, 121 Apr 2024 DOI: 10.1073/pnas.2315575121
Journal Paper Krios I-Titan Krios I at Diamond Krios II-Titan Krios II at Diamond Krios IV-Titan Krios IV at Diamond
Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter Nature Communications, 15 Apr 2024 DOI: 10.1038/s41467-024-47385-3
Expression, purification, and Cryo-EM structural analysis of an outer membrane secretin channel Mar 2024 DOI: 10.1007/978-1-0716-3734-0_18
Book Chapter Krios II-Titan Krios II at Diamond
A service-based approach to cryoEM facility processing pipelines at eBIC Acta Crystallographica Section D Structural Biology, 80 Mar 2024 DOI: 10.1107/S2059798324000986
Journal Paper Krios I-Titan Krios I at Diamond Krios II-Titan Krios II at Diamond Krios III-Titan Krios III at Diamond Krios IV-Titan Krios IV at Diamond Krios V-Titan Krios V at Diamond open access
Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency Nature Communications, 15 Mar 2024 DOI: 10.1038/s41467-024-46235-6
Structural basis for the modulation of MRP2 activity by phosphorylation and drugs Nature Communications, 15 Mar 2024 DOI: 10.1038/s41467-024-46392-8
A structural and dynamic visualization of the interaction between MAP7 and microtubules Nature Communications, 15 Mar 2024 DOI: 10.1038/s41467-024-46260-5
The binding and mechanism of a positive allosteric modulator of Kv3 channels Nature Communications, 15 Mar 2024 DOI: 10.1038/s41467-024-46813-8
Structure of the plant plastid-encoded RNA polymerase Cell, 187 Feb 2024 DOI: 10.1016/j.cell.2024.01.036
Filament structure and subcellular organization of the bacterial intermediate filament–like protein crescentin Proceedings Of The National Academy Of Sciences, 121 Feb 2024 DOI: 10.1073/pnas.2309984121
A new family of bacterial ribosome hibernation factors Nature, 52 Feb 2024 DOI: 10.1038/s41586-024-07041-8
Understanding the power of movement in plants Feb 2024
Science Highlight Krios II-Titan Krios II at Diamond
Structural basis of σ54 displacement and promoter escape in bacterial transcription Proceedings Of The National Academy Of Sciences, 121 Jan 2024 DOI: 10.1073/pnas.2309670120
Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4−/− mouse The Embo Journal, 1861 Jan 2024 DOI: 10.1038/s44318-023-00001-4
- Yaqi Sun, Yuewen Sheng, Tao Ni, Xingwu Ge, Joscelyn Sarsby, Philip J. Brownridge, Kang Li, Nathan Hardenbrook, Gregory F. Dykes, Nichola Rockliffe, Claire E. Eyers, Peijun Zhang, Lu-Ning Liu, "Rubisco packaging and stoichiometric composition of the native β-carboxysome in Synechococcus elongatus PCC7942", Plant Physiology (2024), DOI: 10.1093/plphys/kiae665
- Jianbing Ma, Gangshun Yi, Mingda Ye, Craig Macgregor-Chatwin, Yuewen Sheng, Ying Lu, Ming Li, Qingrong Li, Dong Wang, Robert J. C. Gilbert, Peijun Zhang, "Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-53745-w
- Matthew C. Gaines, Michail N. Isupov, Mathew Mclaren, Clara L. Mollat, Risat U. I. Haque, Jake K. Stephenson, Shamphavi Sivabalasarma, Cyril Hanus, Daniel Kattnig, Vicki A. M. Gold, Sonja Albers, Bertram Daum, "Towards a molecular picture of the archaeal cell surface", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-53986-9
- Alexander Carver, Tai-Yuan Yu, Luke A. Yates, Travis White, Raymond Wang, Katie Lister, Maria Jasin, Xiaodong Zhang, "Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin", Science (2024), DOI: 10.1126/science.adr7920
- Yaqi Sun, Taiyu Chen, Xingwu Ge, Tao Ni, Gregory F. Dykes, Peijun Zhang, Fang Huang, Lu-Ning Liu, "Engineering CO2-fixing modules in E. coli via efficient assembly of cyanobacterial Rubisco and carboxysomes", Plant Communications (2024), DOI: 10.1016/j.xplc.2024.101217
- Souvik Naskar, Andrea Merino, Javier Espadas, Jayanti Singh, Aurelien Roux, Adai Colom, Harry H. Low, "Mechanism for Vipp1 spiral formation, ring biogenesis, and membrane repair", Nature Structural & Molecular Biology, 184 (2024), DOI: 10.1038/s41594-024-01401-8
- Ehud Bino, Lior Aram, Debojit Paul, Yuval Kadan, Daniel Clare, James B. Gilchrist, Nadav Elad, Assaf Gal, "The role of macromolecular condensates in the regulation of intracellular calcium transport for coccolith formation", Advanced Functional Materials, 41 (2024), DOI: 10.1002/adfm.202415344
- Paul Girvan, Adam S. B, Jalal, Elizabeth A. Mccormack, Michael T. Skehan, Carol L. Knight, Dale B. Wigley, David S. Rueda, "Nucleosome flipping drives kinetic proofreading and processivity by SWR1", Nature, 12 (2024), DOI: 10.1038/s41586-024-08152-y
- Hannah Wapenaar, Gillian Clifford, Willow Rolls, Moira Pasquier, Hayden Burdett, Yujie Zhang, Gauri Deak, Juan Zou, Christos Spanos, Mark R. D. Taylor, Jacquie Mills, James A. Watson, Dhananjay Kumar, Richard Clark, Alakta Das, Devisree Valsakumar, Janice Bramham, Philipp Voigt, Duncan Sproul, Marcus D. Wilson, "The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment", Embo Reports, 18 (2024), DOI: 10.1038/s44319-024-00306-3
- [Conference Paper] Eilis Bragginton, Miles Graham, Liam Mead, Matthew Byrne, Karen Davies, "Structural characterisation of a phage-like bacteriocin from Pseudomonas sp. by cryo-Electron Microscopy" (2024), DOI: 10.1051/bioconf/202412921010
- Ana Crespillo-Casado, Prathyush Pothukuchi, Katerina Naydenova, Matthew C. J. Yip, Janet M. Young, Jerome Boulanger, Vimisha Dharamdasani, Ceara Harper, Pierre-Mehdi Hammoudi, Elsje G. Otten, Keith Boyle, Mayuri Gogoi, Harmit S. Malik, Felix Randow, "Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213", Embo Reports, 74 (2024), DOI: 10.1038/s44319-024-00280-w
- Charlotte Crowe, Mark A. Nakasone, Sarah Chandler, Conner Craigon, Gajanan Sathe, Michael H. Tatham, Nikolai Makukhin, Ronald T. Hay, Alessio Ciulli, "Mechanism of degrader-targeted protein ubiquitinability", Science Advances, 10 (2024), DOI: 10.1126/sciadv.ado6492
- Bozhidar S. Ivanov, Hannah R. Bridges, Owen D. Jarman, Judy Hirst, "Structure of the turnover-ready state of an ancestral respiratory complex I", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-53679-3
- Yufei Xiang, Jialu Xu, Briana L. Mcgovern, Anna Ranzenigo, Wei Huang, Zhe Sang, Juan Shen, Randy Diaz-Tapia, Ngoc Dung Pham, Abraham J. P. Teunissen, M. Luis Rodriguez, Jared Benjamin, Derek J. Taylor, Mandy M. T. Van Leent, Kris M. White, Adolfo García-Sastre, Peijun Zhang, Yi Shi, "Adaptive multi-epitope targeting and avidity-enhanced nanobody platform for ultrapotent, durable antiviral therapy", Cell, 19 (2024), DOI: 10.1016/j.cell.2024.09.043
- Marina Serna, Fabian Zimmermann, Chithran Vineethakumari, Nayim Gonzalez-Rodriguez, Oscar Llorca, Jens Lüders, "CDK5RAP2 activates microtubule nucleator γTuRC by facilitating template formation and actin release", Developmental Cell, 28 (2024), DOI: 10.1016/j.devcel.2024.09.001
- Lior Aram, Diede De Haan, Neta Varsano, James B. Gilchrist, Christoph Heintze, Ron Rotkopf, Katya Rechav, Nadav Elad, Nils Kröger, Assaf Gal, "Intracellular morphogenesis of diatom silica is guided by local variations in membrane curvature", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-52211-x
- Adam S. B. Jalal, Paul Girvan, Eugene Y. D. Chua, Lexin Liu, Shijie Wang, Elizabeth A. Mccormack, Michael T. Skehan, Carol L. Knight, David S. Rueda, Dale B. Wigley, "Stabilization of the hexasome intermediate during histone exchange by yeast SWR1 complex", Molecular Cell, 12 (2024), DOI: 10.1016/j.molcel.2024.08.015
- Clarissa N. Pacyna, Madhanagopal Anandapadamanaban, Kevin W. Loudon, Iain M. Hay, Olga Perisic, Ruoyan Li, Matthew Byrne, Laura Allen, Kirsty Roberts, Yvette Hooks, Anne Y. Warren, Grant D. Stewart, Menna R. Clatworthy, Sarah A. Teichmann, Sam Behjati, Peter J. Campbell, Roger L. Williams, Thomas J. Mitchell, "Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis", Oncogene, 23 (2024), DOI: 10.1038/s41388-024-03137-7
- Victoria A. Avanzato, Trenton Bushmaker, Kasopefoluwa Y. Oguntuyo, Claude Kwe Yinda, Helen M. E. Duyvesteyn, Robert Stass, Kimberly Meade-White, Rebecca Rosenke, Tina Thomas, Neeltje Van Doremalen, Greg Saturday, Katie J. Doores, Benhur Lee, Thomas A. Bowden, Vincent J. Munster, "A monoclonal antibody targeting the Nipah virus fusion glycoprotein apex imparts protection from disease", Journal Of Virology (2024), DOI: 10.1128/jvi.00638-24
- Kegomoditswe Malebo, Jeremy Woodward, Phindile Ximba, Qiniso Mkhize, Sanele Cingo, Thandeka Moyo-Gwete, Penny L. Moore, Anna-Lise Williamson, Rosamund Chapman, "Development of a two-component nanoparticle vaccine displaying an HIV-1 envelope glycoprotein that elicits tier 2 neutralising antibodies", Vaccines, 12 (2024), DOI: 10.3390/vaccines12091063
- Michael Hohl, Emma J. Banks, Max P. Manley, Tung B. K. Le, Harry H. Low, "Bidirectional pilus processing in the Tad pilus system motor CpaF", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-50280-6
- Rhianna J. Rowland, Svitlana Korolchuk, Marco Salamina, Natalie J. Tatum, James R. Ault, Sam Hart, Johan P. Turkenburg, James N. Blaza, Martin E. M. Noble, Jane A. Endicott, "Cryo-EM structure of the CDK2-cyclin A-CDC25A complex", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-51135-w
- James Hillier, Yuguang Zhao, Loic Carrique, Tomas Malinauskas, Reinis R. Ruza, Tao-Hsin Chang, Gangshun Yi, Helen M. E. Duyvesteyn, Jing Yu, Weixian Lu, Els Pardon, Jan Steyaert, Yanan Zhu, Tao Ni, E. Yvonne Jones, "Structural insights into Frizzled3 through nanobody modulators", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-51451-1
- Martin L. Rennie, Mehmet Gundogdu, Connor Arkinson, Steven Liness, Sheelagh Frame, Helen Walden, "Structural and biochemical insights into the mechanism of action of the clinical USP1 inhibitor, KSQ-4279", Journal Of Medicinal Chemistry (2024), DOI: 10.1021/acs.jmedchem.4c01184
- Gangshun Yi, Mingda Ye, Loic Carrique, Afaf H. El-Sagheer, Tom Brown, Chris J. Norbury, Peijun Zhang, Robert J. C. Gilbert, "Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs", Nature Structural & Molecular Biology, 20 (2024), DOI: 10.1038/s41594-024-01357-9
- Natalia De Martin Garrido, Chao-Sheng Chen, Kailash Ramlaul, Christopher H. S. Aylett, Maria Yakunina, "Structure of the bacteriophage PhiKZ non-virion RNA polymerase transcribing from its promoter p119L", Journal Of Molecular Biology, 15 (2024), DOI: 10.1016/j.jmb.2024.168713
- Chisato Tsuji, Marston Bradshaw, Megan F. Allen, Molly L. Jackson, Judith Mantell, Ufuk Borucu, Alastair W. Poole, Paul Verkade, Ingeborg Hers, Danielle M. Paul, Mark P. Dodding, "CryoET reveals actin filaments within platelet microtubules", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-50424-8
- Pablo Alcon, Artur P. Kaczmarczyk, Korak Kumar Ray, Themistoklis Liolios, Guillaume Guilbaud, Tamara Sijacki, Yichao Shen, Stephen H. Mclaughlin, Julian E. Sale, Puck Knipscheer, David S. Rueda, Lori A. Passmore, "FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions", Nature, 90 (2024), DOI: 10.1038/s41586-024-07770-w
- [Science Highlight] Diamond Light Source, "A first peek at a "crass" virus" (2024)
- Vojtěch Pražák, Yuliia Mironova, Daven Vasishtan, Christoph Hagen, Ulrike Laugks, Yannick Jensen, Saskia Sanders, John M. Heumann, Barbara G. Klupp, Thomas C. Mettenleiter, Michael Grange, Kay Grunewald, Jens B. Bosse, "Molecular plasticity of herpesvirus nuclear egress analysed in situ", Nature Microbiology, 9, 1842 - 1855 (2024), DOI: 10.1038/s41564-024-01716-8
- Paul B. Klar, David G. Waterman, Tim Gruene, Debakshi Mullick, Yun Song, James B. Gilchrist, C. David Owen, Wen Wen, Idan Biran, Lothar Houben, Neta Regev-Rudzki, Ron Dzikowski, Noa Marom, Lukas Palatinus, Peijun Zhang, Leslie Leiserowitz, Michael Elbaum, "Cryo-tomography and 3D electron diffraction reveal the polar habit and chiral structure of the malaria pigment crystal hemozoin", Acs Central Science (2024), DOI: 10.1021/acscentsci.4c00162
- Alexander T. Bakker, Ioli Kotsogianni, Mariana Avalos, Jeroen M. Punt, Bing Liu, Diana Piermarini, Berend Gagestein, Cornelis J. Slingerland, Le Zhang, Joost J. Willemse, Leela B. Ghimire, Richard J. H. B. N. Van Den Berg, Antonius P. A. Janssen, Tom H. M. Ottenhoff, Constant A. A. Van Boeckel, Gilles P. Van Wezel, Dmitry Ghilarov, Nathaniel I. Martin, Mario Van Der Stelt, "Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria", Nature Chemistry, 399 (2024), DOI: 10.1038/s41557-024-01516-x
- Daniel N. Grba, John J. Wright, Zhan Yin, William Fisher, Judy Hirst, "Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I", Science, 384, 1247 - 1253 (2024), DOI: 10.1126/science.ado2075
- Matthew C. Gaines, Shamphavi Sivabalasarma, Michail N. Isupov, Risat U. I. Haque, Mathew Mclaren, Cyril Hanus, Vicki A. M. Gold, Sonja-Verena Albers, Bertram Daum, "CryoEM reveals the structure of an archaeal pilus involved in twitching motility", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-45831-w
- Álvaro De La Gándara, Mercedes Spínola-Amilibia, Lidia Araujo-Bazan, Rafael Nunez-Ramirez, James M. Berger, Ernesto Arias-Palomo, "Molecular basis for transposase activation by a dedicated AAA+ ATPase", Nature, 630, 1003 - 1011 (2024), DOI: 10.1038/s41586-024-07550-6
- Huanyu Z. Li, Ashley C. W. Pike, Irina Lotsaris, Gamma Chi, Jesper S. Hansen, Sarah C. Lee, Karin E. J. Roedstroem, Simon R. Bushell, David Speedman, Adam Evans, Dong Wang, Didi He, Leela Shrestha, Chady Nasrallah, Nicola A. Burgess-Brown, Robert J. Vandenberg, Timothy R. Dafforn, Elisabeth P. Carpenter, David B. Sauer, "Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-48921-x
- Sanjeev Ranjan, Stef Bosch, Hannamari Lukkari, Johanna Schirmer, Niina Aaltonen, Heikki J. Nieminen, Vesa-Pekka Lehto, Arto Urtti, Tatu Lajunen, Kirsi Rilla, "Development of focused ultrasound-assisted nanoplexes for RNA delivery", Nanomaterials, 14 (2024), DOI: 10.3390/nano14131089
- Stephen C. L. Hall, David J. Hardy, Eilis C. Bragginton, Hannah Johnston, Tudor Onose, Rachel Holyfield, Pooja Sridhar, Timothy J. Knowles, Luke A. Clifton, "Distance tuneable integral membrane protein containing floating bilayers via in situ directed self-assembly", Nanoscale, 277 (2024), DOI: 10.1039/D3NR04622B
- Gamma Chi, Dawid Jaślan, Veronika Kudrina, Julia Böck, Huanyu Li, Ashley C. W. Pike, Susanne Rautenberg, Einar Krogsaeter, Tina Bohstedt, Dong Wang, Gavin Mckinley, Alejandra Fernandez-Cid, Shubhashish M. M. Mukhopadhyay, Nicola A. Burgess-Brown, Marco Keller, Franz Bracher, Christian Grimm, Katharina L. Dürr, "Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist", Structure, 594 (2024), DOI: 10.1016/j.str.2024.05.005
- [Science Highlight] Diamond Light Source, "Understanding a protein that fuels bowel cancer" (2024)
- [Thesis] Ernesto Arias-Palomo, "Structural and molecular mechanisms af ATP-dependent DNA transposition using IS21 as a model system" (2024)
- Daniel Hatton, Jaehoon Cha, Stephen Riggs, Peter Harrison, Jeyan Thiyagalingam, Daniel K. Clare, Kyle L. Morris, "EMinsight : a tool to capture cryoEM microscope configuration and experimental outcomes for analysis and deposition", Acta Crystallographica Section D Structural Biology, 80, 259 - 269 (2024), DOI: 10.1107/S2059798324001578
- Dawid S. Zyla, Thomas Wiegand, Paul Bachmann, Rafal Zdanowicz, Christoph Giese, Beat H. Meier, Gabriel Waksman, Manuela K. Hospenthal, Rudi Glockshuber, "The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-47212-9
- Thomas J. Mccorvie, Douglas Adamoski, Raquel A. C. Machado, Jiazhi Tang, Henry J. Bailey, Douglas S. M. Ferreira, Claire Strain-Damerell, Arnaud Basle, Andre L. B. Ambrosio, Sandra M. G. Dias, Wyatt W. Yue, "Architecture and regulation of filamentous human cystathionine beta-synthase", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-46864-x
- Kelly M. Frain, Emil Dedic, Lynette Nel, Anastasiia Bohush, Esben Olesen, Katja Thaysen, Daniel Wüstner, David L. Stokes, Bjorn Panyella Pedersen, "Conformational changes in the Niemann–Pick type C1 protein NCR1 drive sterol translocation", Proceedings Of The National Academy Of Sciences, 121 (2024), DOI: 10.1073/pnas.2315575121
- Josep Rullo-Tubau, Maria Martinez-Molledo, Paola Bartoccioni, Ignasi Puch-Giner, Ángela Arias, Suwipa Saen-Oon, Camille Stephan-Otto Attolini, Rafael Artuch, Lucía Díaz, Víctor Guallar, Ekaitz Errasti-Murugarren, Manuel Palacin, Oscar Llorca, "Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-47385-3
- [Book Chapter] Rebecca Conners, Mathew Mclaren, Marjorie Russel, Vicki A. M. Gold, "Expression, purification, and Cryo-EM structural analysis of an outer membrane secretin channel" (2024), DOI: 10.1007/978-1-0716-3734-0_18
- Anna Horstmann, Stephen Riggs, Yuriy Chaban, Daniel K. Clare, Guilherme De Freitas, David Farmer, Andrew Howe, Kyle L. Morris, Daniel Hatton, "A service-based approach to cryoEM facility processing pipelines at eBIC", Acta Crystallographica Section D Structural Biology, 80 (2024), DOI: 10.1107/S2059798324000986
- Scott Gardner, Yibo Jin, Paul K. Fyfe, Tomas B. Voisin, Junel Sotolongo Bellón, Elizabeth Pohler, Jacob Piehler, Ignacio Moraga, Doryen Bubeck, "Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-46235-6
- Tiziano Mazza, Theodoros I. Roumeliotis, Elena Garitta, David Drew, S. Tamir Rashid, Cesare Indiveri, Jyoti S. Choudhary, Kenneth J. Linton, Konstantinos Beis, "Structural basis for the modulation of MRP2 activity by phosphorylation and drugs", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-46392-8
- Agnes Adler, Mamata Bangera, J. Wouter Beugelink, Salima Bahri, Hugo Van Ingen, Carolyn A. Moores, Marc Baldus, "A structural and dynamic visualization of the interaction between MAP7 and microtubules", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-46260-5
- Qiansheng Liang, Gamma Chi, Leonardo Cirqueira, Lianteng Zhi, Agostino Marasco, Nadia Pilati, Martin J. Gunthorpe, Giuseppe Alvaro, Charles H. Large, David B. Sauer, Werner Treptow, Manuel Covarrubias, "The binding and mechanism of a positive allosteric modulator of Kv3 channels", Nature Communications, 15 (2024), DOI: 10.1038/s41467-024-46813-8
- Ángel Vergara-Cruces, Ishika Pramanick, David Pearce, Vinod K. Vogirala, Matthew J. Byrne, Jason K. K. Low, Michael W. Webster, "Structure of the plant plastid-encoded RNA polymerase", Cell, 187, 1145 - 1159.e21 (2024), DOI: 10.1016/j.cell.2024.01.036
- Yue Liu, Fusinita Van Den Ent, Jan Lowe, "Filament structure and subcellular organization of the bacterial intermediate filament–like protein crescentin", Proceedings Of The National Academy Of Sciences, 121 (2024), DOI: 10.1073/pnas.2309984121
- Karla Helena-Bueno, Mariia Yu. Rybak, Chinenye L. Ekemezie, Rudi Sullivan, Charlotte R. Brown, Charlotte Dingwall, Arnaud Basle, Claudia Schneider, James P. R. Connolly, James N. Blaza, Bálint Csörgő, Patrick J. Moynihan, Matthieu G. Gagnon, Chris H. Hill, Sergey V. Melnikov, "A new family of bacterial ribosome hibernation factors", Nature, 52 (2024), DOI: 10.1038/s41586-024-07041-8
- [Science Highlight] Diamond Light Source, "Understanding the power of movement in plants" (2024)
- Forson Gao, Fuzhou Ye, Bowen Zhang, Nora Cronin, Martin Buck, Xiaodong Zhang, "Structural basis of σ54 displacement and promoter escape in bacterial transcription", Proceedings Of The National Academy Of Sciences, 121 (2024), DOI: 10.1073/pnas.2309670120
- Zhan Yin, Ahmed-Noor A. Agip, Hannah R. Bridges, Judy Hirst, "Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4−/− mouse", The Embo Journal, 1861 (2024), DOI: 10.1038/s44318-023-00001-4
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
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