Macromolecules tend to form small, imperfect and weakly diffracting crystals. The high brightness of synchrotron X-rays makes the collection of precise measurements possible. Automated remote sample handling systems allow high throughput for testing samples.
Rational drug design, enzyme mechanisms, supramolecular structure, molecular recognition, nucleic acids, structural genomics, high throughput crystallography.
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
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