Maud Dumoux

Maud has a PhD in immunology from Paris 7 Diderot. Prior to working at the Rosalind Franklin Institute (RFI), she worked at the Institute of Structural and Molecular Biology and Diamond Light Source. She is interested in the development of imaging modalities and host pathogen interactions.

 

Krasnoselska, G.O. et al. (2021). Transient Transfection and Expression of Eukaryotic Membrane Proteins in Expi293F Cells and Their Screening on a Small Scale: Application for Structural Studies. In: Owens, R.J. (eds) Structural Proteomics. Methods in Molecular Biology, vol 2305. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1406-8_5

Okolo, CA, Jadhav, A, Phillips, P, et al. Correlative imaging using super-resolution fluorescence microscopy and soft X-ray tomography at cryogenic temperatures provides a new way to assess virosome solutions for vaccine development. Journal of Microscopy. 2021; 284: 214– 232. https://doi.org/10.1111/jmi.13054

Phillips P, Parkhurst JM, Kounatidis I, Okolo C, Fish TM, Naismith JH, Walsh MA, Harkiolaki M, Dumoux M. Single Cell Cryo-Soft X-ray Tomography Shows That Each Chlamydia Trachomatis Inclusion Is a Unique Community of Bacteria. Life. 2021; 11(8):842. https://doi.org/10.3390/life11080842

Huo, J., Bas, A.L., Ruza, R.R. et al. Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2. Nat Struct Mol Biol 28, 326 (2021). https://doi.org/10.1038/s41594-021-00566-w

Andrew SC, Dumoux M, Hayward RD. Chlamydia Uses K⁺ Electrical Signalling to Orchestrate Host Sensing, Inter-Bacterial Communication and Differentiation. Microorganisms. 2021; 9(1):173. https://doi.org/10.3390/microorganisms9010173

Kim, Y.C., Dumoux, M., Owens, R.J., Reyes-Sandoval, A. (2020). Optimization of Small-Scale Production of Zika Virus Envelope Glycoprotein by Transient Expression in HEK293 Cells for ELISA. In: Kobinger, G., Racine, T. (eds) Zika Virus. Methods in Molecular Biology, vol 2142. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0581-3_9

Huo, J., Le Bas, A., Ruza, R.R. et al. Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2. Nat Struct Mol Biol 27, 846–854 (2020). https://doi.org/10.1038/s41594-020-0469-6

Ahmed, A.R., Owens, R.J., Stubbs, C.D. et al. Direct imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells. Sci Rep 9, 3408 (2019). https://doi.org/10.1038/s41598-019-39410-z

Prevost MS, Pinotsis N, Dumoux M, Hayward RD, Waksman G. The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery. Scientific Reports. 2017 Aug;7(1):9450. DOI: 10.1038/s41598-017-10249-6. PMID: 28842705; PMCID: PMC5572681.

Dumoux M, Hayward RD. Membrane contact sites between pathogen-containing compartments and host organelles. Biochimica et Biophysica Acta. 2016 Aug;1861(8 Pt B):895-899. DOI: 10.1016/j.bbalip.2016.01.018. PMID: 26825687.

Clare DK, Dumoux M, Delacour D. In vivo examination of the cortical cytoskeleton in multiciliated cells using electron tomography. Methods in Cell Biology. 2015;129:61-82. DOI: 10.1016/bs.mcb.2015.03.001. PMID: 26175434.

Dumoux M, Menny A, Delacour D, Hayward RD. A Chlamydia effector recruits CEP170 to reprogram host microtubule organization. Journal of Cell Science. 2015 Sep;128(18):3420-3434. DOI: 10.1242/jcs.169318. PMID: 26220855; PMCID: PMC4582400.

Dumoux M, Nans A, Saibil HR, Hayward RD. Making connections: snapshots of chlamydial type III secretion systems in contact with host membranes. Current Opinion in Microbiology. 2015 Feb;23:1-7. DOI: 10.1016/j.mib.2014.09.019. PMID: 25461566.

Clare DK, Magescas J, Piolot T, et al. Basal foot MTOC organizes pillar MTs required for coordination of beating cilia. Nature Communications. 2014 Sep;5:4888. DOI: 10.1038/ncomms5888. PMID: 25215410; PMCID: PMC4993237.

Dumoux M, Le Gall SM, Habbeddine M, et al. Penicillin kills Chlamydia following the fusion of bacteria with lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice. Plos one. 2013 ;8(12):e83511. DOI: 10.1371/journal.pone.0083511. PMID: 24376710; PMCID: PMC3871543.

Barry D, Roque H, Dumoux M, et al. Meeting report - imaging in cell biology: where next? Journal of Cell Science. 2013 Jan;126(Pt 1):43-44. DOI: 10.1242/jcs.129197. PMID: 23516329.

Dumoux M, Clare DK, Saibil HR, Hayward RD. Chlamydiae assemble a pathogen synapse to hijack the host endoplasmic reticulum. Traffic (Copenhagen, Denmark). 2012 Dec;13(12):1612-1627. DOI: 10.1111/tra.12002. PMID: 22901061; PMCID: PMC3533787.