Alistair Siebert
Tel: +44 (0) 1235 77 8356
E-mail: alistair.siebert@diamond.ac.uk
Daniel Clare
Tel: +44 (0) 1235 56 7501
E-mail: daniel.clare@diamond.ac.uk
The Electron Bio-Imaging Centre (eBIC) was established at Diamond following the award of a
£15.6 million grant from the Wellcome Trust, the Medical Research Council (MRC) and the
Biotechnology and Biological Sciences Research Council (BBSRC). The location of eBIC
enables scientists to combine their techniques with many of the other cutting-edge approaches
that Diamond offers; whilst a partnership with the University of Oxford allows users to access
the Polara, a high-containment cryo-electron microscope.
eBIC provides scientists with state-of-the-art experimental equipment and expertise in the field
of cryo-electron microscopy, for both single particle analysis and cryo-tomography. Currently
eBIC houses five Titan Krios microscopes, a Talos Arctica, Glacios, and a Scios and Aquilos cryo-FIB/SEM.
eBIC is pleased to announce its first user meeting on 29th April 2019. It will take place in Nottingham in collaboration with CCP-EM and their Spring Symposium. Sign up on the event website before the 25 January for an Early Bird discount:
eBIC is recruiting for a Principal Electron Microscope Scientist. This is an exciting group-leader level position. Deadline 4th Jan 2019. Please click here to find out more.
Shipping samples to eBIC? New process launched at eBIC relying on barcodes. Please use ISPyB to generate your barcode and attach to your dewar.
First eBIC user meeting planned for Monday 29th April 2019, Nottingham, leading into the CCP-EM spring symposium on Tues 30th April & Wed 1st May.
Third cryoEM sample preparation workshop begins
eBIC offically opened by Nobel prize winner Richard Henderson
eBIC control room now fully operational for remote control access to all Krios microscopes.
First BAG super user accreditation/training successfully completed.
eBIC welcomes three new members of staff, Katie Cunnea (Centre coordinator) James Gilchrist (Support Scientist) and Zhengyi Yang (Postdoc).
Krios II welcomes its first users from the University of Oxford
Krios I welcomes first users from MRC LMB Cambridge
[Publication] A national facility for biological cryo-electron microscopy. Saibil, H. R., Grunewald, K. & Stuart, D. I. (2015). Acta Cryst. D 71, 127-135. DOI: 10.1107/S1399004714025280
CryoFIB applications NOW OPEN
The cryoFIB instruments are now open for 'Rapid' and 'Standard' applications (see below).
In all cases, grid quality (ice thickness, sample density, etc.) will be assessed before progressing to further stages of review. Milling will be performed on a maximum of two autogrids per day.
All proposals should be submitted online via the UAS
If you have any questions please contact james.gilchrist@diamond.ac.uk
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
Copyright © 2018 Diamond Light Source
Diamond Light Source Ltd
Diamond House
Harwell Science & Innovation Campus
Didcot
Oxfordshire
OX11 0DE
Biological Cryo-Imaging
eBIC
Macromolecular
Soft Condensed 
Imaging and
Biological
Magnetic
Structures and
Crystallography 
Spectroscopy 
Some members of the eBIC team.
The Titan Krios Hall, where three of the four Krios are housed.
