eBIC: Electron Bio-Imaging Centre

 CryoFIB user program

Submit your proposal

• For lamella preparation on frozen cells and microcrystals

• On-grid FIB milling only

• Rapid and BAG access

For more information please see here (download).

We are pleased to announce a commissioning call for researchers to access the chameleon cryo-EM freezing device (application) developed commercially by SPT Labtech. This forms part of a collaboration between Diamond, the Rosalind Franklin Institute and SPT Labtech with the view to providing a platform for beta-testing of the chameleon by the wider user community that will aid further commercialisation of the system by SPT Labtech.

The chameleon uses piezo electric inkjet dispensing technology to apply nanolitre volumes of protein solution to self-wicking cryo-EM grids.

Please select the Rapid access route and the Talos instrument when you submit your proposal and also add that this is specifically for use with the chameleon.

• Proposals are also open to existing BAG PIs.
• Proposals will be reviewed by eBIC staff with a view to schedule beamtime from December/January.
• Please follow this link for details about requirements and visit structure (download).
• For inquiries please contact daniel.clare@diamond.ac.uk.

Principal Electron Microscopy Software Scientist

We now have an exciting opportunity at group-leader level for a Principal EM Scientist to underpin and further develop eBIC as a leading centre for cryoEM. eBIC together with B24, which provides a full-field cryo X-ray transmission microscope and a bespoke 3D super resolution fluorescence cryo-imaging microscope, makeup the Biological Cryo-Imaging group at Diamond. We work closely with the Imaging and Microscopy group in particular ePSIC, the physical sciences electron imaging centre. Overall, we provide an extraordinarily strong imaging platform for using electrons, X-rays and visible light to image a diverse range of samples across a range of length and time scales.

As a Principal EM Scientist at eBIC you will,

• Lead a small team of scientists to establish a competitive research programme which exploits the capabilities of eBIC and Diamond in general
• Take part in the management of the operation, maintenance, and development of eBIC, in particular in software development relating to cryoEM/ET data analysis

Read more here...Principal Electron Microscopy Software Scientist