The Electron Bio-Imaging Centre (eBIC) was established at Diamond following the award
of a £15.6 million grant from the Wellcome Trust, the Medical Research Council (MRC) and
the Biotechnology and Biological Sciences Research Council (BBSRC).
The location of eBIC enables scientists to combine their techniques with many of the other
cutting-edge approaches that Diamond offers.
eBIC provides scientists with state-of-the-art experimental equipment and expertise in the
field of cryo-electron microscopy, for both single particle analysis and cryo-tomography.
Currently eBIC houses five Titan Krios microscopes, a Talos Arctica, Glacios, and
a Scios and Aquilos cryo-FIB/SEM.
Access to eBIC is available and currently operating under general beamline guidelines.
We are able to offer remote access, unattended automated data collection and mail-in services
for all research areas (currently only available: data collection using EPU).
COVID-19 research should be requested
through rapid access proposals following
For eBIC specific access: Instructions for unattended automated data collection.
* please note: Diamond EHC are available for support, providing 24hour coverage during
the week when the beamline is on. Over the weekend EHC coverage is for 12hours
only from 7am-7pm (Saturday & Sunday) *
Read about eBIC team changes
Advance work on SARS-CoV-2
eBIC User ‘virtual’ meeting
CryoFIB user program
Submit your proposal
• For lamella preparation on frozen
cells and microcrystals
• On-grid FIB milling only
• Rapid access
For more information please see here
We are pleased to announce a commissioning call for researchers to access the chameleon cryo-EM freezing device (application) developed commercially by SPT Labtech. This forms part of a collaboration between Diamond, the Rosalind Franklin Institute and SPT Labtech with the view to providing a platform for beta-testing of the chameleon by the wider user community that will aid further commercialisation of the system by SPT Labtech.
The chameleon uses piezo electric inkjet dispensing technology to apply nanolitre volumes of protein solution to self-wicking cryo-EM grids.
Please select the Rapid access route and the Talos instrument when you submit your proposal and also add that this is specifically for use with the chameleon.
Proposals are also open to existing BAG PIs.
Proposals will be reviewed by eBIC staff with a view to schedule beamtime from December/January.
Please follow this link for details about requirements and visit structure.
For inquiries please contact firstname.lastname@example.org
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