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The electron Bio-Imaging Centre (eBIC) was established at Diamond Light Source following the award of a £15.6 million grant from the Wellcome Trust, the Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC).
eBIC provides scientists with state-of-the-art experimental equipment and expertise in the field of cryo-electron microscopy, for single particle analysis, electron tomography and electron diffraction. The location of eBIC enables scientists to combine their techniques with many of the other cutting-edge approaches that Diamond offers.
Currently eBIC houses five Titan Krios microscopes, a Talos Arctica, two Glacios, a Scios and an Aquilos cryo-FIB/SEM, and a Leica CryoCLEM.
Access to eBIC is available and currently operating under general beamline guidelines.
We are able to offer remote access, unattended automated data collection and mail-in services for all research areas (currently only available: data collection using EPU).
COVID-19 research should be requested through rapid access proposals following these instructions.
NOTE: Diamond EHC are available for support, providing 24hour coverage during the week when the beamline is on. Over the weekend EHC coverage is for 12hours only from 7am-7pm (Saturday & Sunday).
CryoFIB user program
Submit your proposal
• For lamella preparation on frozen cells and microcrystals
• On-grid FIB milling only
• Rapid and BAG access
For more information please see here (download).
We are pleased to announce a commissioning call for researchers to access the chameleon cryo-EM freezing device (application) developed commercially by SPT Labtech. This forms part of a collaboration between Diamond, the Rosalind Franklin Institute and SPT Labtech with the view to providing a platform for beta-testing of the chameleon by the wider user community that will aid further commercialisation of the system by SPT Labtech.
The chameleon uses piezo electric inkjet dispensing technology to apply nanolitre volumes of protein solution to self-wicking cryo-EM grids.
Please select the Rapid access route and the Talos instrument when you submit your proposal and also add that this is specifically for use with the chameleon.
Principal Electron Microscopy Software Scientist
We now have an exciting opportunity at group-leader level for a Principal EM Scientist to underpin and further develop eBIC as a leading centre for cryoEM. eBIC together with B24, which provides a full-field cryo X-ray transmission microscope and a bespoke 3D super resolution fluorescence cryo-imaging microscope, makeup the Biological Cryo-Imaging group at Diamond. We work closely with the Imaging and Microscopy group in particular ePSIC, the physical sciences electron imaging centre. Overall, we provide an extraordinarily strong imaging platform for using electrons, X-rays and visible light to image a diverse range of samples across a range of length and time scales.
As a Principal EM Scientist at eBIC you will,
Read more here...Principal Electron Microscopy Software Scientist
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