Current Calls

We are pleased to announce a commissioning call for Cryogenic Correlated Light and Electron Microscopy (Cryo-CLEM) proposals, at eBIC.

Cryo-light and electron microscopy can be used to image and correlate samples in frozen hydrated specimen in a close-to-native state to achieve high-resolution structural data.

• Access to the Leica Cryo Light Microscope (cryoLM), a FIB-SEM if needed, and a Titan Krios fitted with an energy filter and Falcon4i or K3
• For technical inquiries please contact: julika.radecke@diamond.ac.uk or craig.macgregor-chatwin@diamond.ac.uk

For more details please see Cryo-CLEM: Call for proposals and for rapid access details follow the Rapid access route.

Submit your proposal

• For lamella preparation on frozen cells and microcrystals

• On-grid FIB milling only

• Rapid and BAG access

For more information please see here (download).

We are pleased to announce a commissioning call for researchers to access the chameleon cryo-EM freezing device (application) developed commercially by SPT Labtech. This forms part of a collaboration between Diamond, the Rosalind Franklin Institute and SPT Labtech.

The chameleon uses piezo electric inkjet dispensing technology to apply nanolitre volumes of protein solution to self-wicking cryo-EM grids.

Please select the Rapid access route and the Talos instrument when you submit your proposal and also add that this is specifically for use with the chameleon.

• Proposals are also open to existing BAG PIs.
• Proposals will be reviewed by eBIC staff, based on availability.
• Please follow this link for details about requirements and visit structure (download).
• For enquiries please contact david.owen@diamond.ac.uk or lorna.malone@diamond.ac.uk.