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Nature, Dec 2012 DOI: 10.1038/nature11683 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) Substrate channels revealed in the trimeric Lactobacillus reuteri bacterial microcompartment shell protein PduB Allan Pang, Mingzhi Liang, Michael B. Prentice, Richard W. Pickersgill
Acta Crystallographica Section D Biological Crystallography, 68 Dec 2012 DOI: 10.1107/S0907444912039315 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) Structure of ribose 5-phosphate isomerase from the probiotic bacterium Lactobacillus salivarius UCC118 Carina M. C. Lobley, Pierre Aller, Alice Douangamath, Yamini Reddivari, Mario Bumann, Louise E. Bird, Joanne E. Nettleship, Jose Brandao-Neto, Raymond J. Owens, Paul W. O'Toole, Martin A. Walsh
Acta Crystallographica Section F Structural Biology And Crystallization Communications, 68 Dec 2012 DOI: 10.1107/S174430911204273X Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) Crystal structures of MBOgg1 in complex with two abasic DNA ligands Hongjun Yu, Mingzhang Yang, Xian-En Zhang, Lijun Bi, Tao Jiang
Journal Of Structural Biology, 181 (3) Dec 2012 DOI: 10.1016/j.jsb.2012.12.003 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Structural and functional integration of the PLCγ interaction domains critical for regulatory mechanisms and signaling deregulation Tom D. Bunney, Diego Esposito, Corine Mas-Droux, Ekatarina Lamber, Rhona W. Baxendale, Marta Martins, Ambrose Cole, Dmitri Svergun, Paul C. Driscoll, Matilda Katan
Structure, 20 (12) Dec 2012 DOI: 10.1016/j.str.2012.09.005 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa Magnus Alphey, Lisa Pirrie, Leah S. Torrie, Wassila Abdelli Boulkeroua, Mary Gardiner, Aurijit Sarkar, Marko Maringer, Wulf Oehlmann, Ruth Brenk, Michael S. Scherman, Michael Mcneil, Martin Rejzek, Robert A. Field, Mahavir Singh, David Gray, Nicholas J. Westwood, James H. Naismith
Acs Chemical Biology, 8 (2) Nov 2012 DOI: 10.1021/cb300426u Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) open access Molecular basis for recognition of dilysine trafficking motifs by COPI Lauren P. Jackson, Michael Lewis, Helen m. Kent, Melissa a. Edeling, Philip R. Evans, Rainer Duden, David J. Owen
Developmental Cell, Nov 2012 DOI: 10.1016/j.devcel.2012.10.017 Journal Paper I02-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) open access Redox and chemical activities of the hemes in the sulfur oxidation pathway enzyme SoxAX Justin Bradley, Sophie J. Marritt, Margaret A. Kihlken, Kate Haynes, Andrew m. Hemmings, Ben C. Berks, Myles Cheesman, Julea N. Butt
Journal Of Biological Chemistry, 287 (48) Nov 2012 DOI: 10.1074/jbc.M112.396192 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) open access Cloning, expression, purification, crystallization and X-ray analysis of inositol monophosphatase from Mus musculus and Homo sapiens Nisha Singh, Amy C. Halliday, Matthew Knight, Nathan Lack, Ed Lowe, Grant C. Churchill
Acta Crystallographica Section F Structural Biology And Crystallization Communications, 68 (10) Oct 2012 DOI: 10.1107/S1744309112035191 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex Bert J. C. Janssen, Tomas Malinauskas, Greg A. Weir, M. Zameel Cader, Christian Siebold, E. Yvonne Jones
Nature Structural & Molecular Biology, 19 (12) Oct 2012 DOI: 10.1038/nsmb.2416 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) Structure, function, and evolution of the crimean-congo hemorrhagic fever virus nucleocapsid protein Stephen Carter, Rebecca Surtees, Cheryl T Walter, Antonio Ariza, Eric Bergeron, Stuart T Nichol, Julian A Hiscox, Thomas A Edwards, John N Barr
Journal Of Virology, 86 (20) Oct 2012 DOI: 10.1128/JVI.01555-12 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) open access An enzyme-trap approach allows isolation of intermediates in cobalamin biosynthesis Evelyne Deery, Susanne Schroeder, Andrew D. Lawrence, Samantha L. Taylor, Jitka Waterman, Keith S. Wilson, David Brown, Michael A. Geeves, Mark J. Howard, Richard Pickersgill, Martin J. Warren, Arefeh Seyedarabi
Nature Chemical Biology, 8 (11) Oct 2012 DOI: 10.1038/nchembio.1086 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access Design and synthesis of inhibitors of Plasmodium falciparumN-myristoyltransferase, a promising target for antimalarial drug discovery Zhiyong Yu, James A. Brannigan, David K. Moss, Andrzej Marek Brzozowski, Anthony Wilkinson, Anthony A. Holder, Edward W. Tate, Robin J. Leatherbarrow
Journal Of Medicinal Chemistry, 55 (20) Oct 2012 DOI: 10.1021/jm301160h Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) The reaction coordinate of a bacterial GH47 α-mannosidase: a combined quantum mechanical and structural approach Andrew J. Thompson, Jerome Dabin, Javier Iglesias-Fernández, Albert Ardèvol, Zoran Dinev, Spencer J. Williams, Omprakash Bande, Aloysius Siriwardena, Carl Moreland, Ting-Chou Hu, David K. Smith, Harry J. Gilbert, Carme Rovira, Gideon J. Davies
Angewandte Chemie International Edition, 51 (44) Oct 2012 DOI: 10.1002/anie.201205338 Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography Conformational state of the MscS mechanosensitive channel in solution revealed by pulsed electron-electron double resonance (PELDOR) spectroscopy C. Pliotas, R. Ward, E. Branigan, A. Rasmussen, G. Hagelueken, H. Huang, S. S. Black, I. R. Booth, O. Schiemann, J. H. Naismith
Proceedings Of The National Academy Of Sciences, Sept 2012 DOI: 10.1073/pnas.1202286109 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) open access Structure of WbdD; a bifunctional kinase and methyltransferase that regulates the chain length of the O antigen in Escherichia coliO9a Gregor Hagelueken, Hexian Huang, Bradley R. Clarke, Thomas Lebl, Chris Whitfield, James H. Naismith
Molecular Microbiology, Sept 2012 DOI: 10.1111/mmi.12014 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers Chris Holland, Pierre Rizkallah, Sabrina Vollers, J. Mauricio Calvo-Calle, Florian Madura, Anna Fuller, Andrew K. Sewell, Lawrence J. Stern, Andrew Godkin, David K. Cole
Scientific Reports, 2 Sept 2012 DOI: 10.1038/srep00629 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) open access Structure of the catalytic core module of the module of the Chaetomium thermophilum family GH6 cellobiohydrolase Cel6A Andrew J. Thompson, Tia Heu, Tarana Shaghasi, Romil Benyamino, Aubrey Jones, Esben P. Friis, Keith S. Wilson, Gideon J. Davies
Acta Crystallographica Section D Biological Crystallography, 68 (8) Aug 2012 DOI: 10.1107/S0907444912016496 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) TCR/pMHC optimized protein crystallization screen Anna Bulek, Florian Madura, Anna Fuller, Chris Holland, Andrea Schauenburg, Andrew K. Sewell, Pierre J. Rizkallah, David K. Cole
Journal Of Immunological Methods, 382 Aug 2012 DOI: 10.1016/j.jim.2012.06.007 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access Structural basis for catalytic activation of protein Z-dependent protease inhibitor (ZPI) by protein Z X. Huang, Y. Yan, Y. Tu, J. Gatti, G. J. Broze, A. Zhou, S. T. Olson
Blood, 120 (8) Aug 2012 DOI: 10.1182/blood-2012-03-419598 Journal Paper I02-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) Characterization of the Interaction of Sclerostin with the Low Density Lipoprotein Receptor-related Protein (LRP) Family of Wnt Co-receptors Gill Holdsworth, Patrick Slocombe, Carl Doyle, Bernadette Sweeney, Vaclav Veverka, Kelly Le Riche, Richard J. Franklin, Joanne Compson, Daniel Brookings, James Turner, Jeffery Kennedy, Rachel Garlish, Jiye Shi, Laura Newnham, David Mcmillan, Mariusz Muzylak, Mark D. Carr, A. J. Henry, T. Ceska, M. K. Robinson
Journal Of Biological Chemistry, 287 Aug 2012 DOI: 10.1074/jbc.M112.350108 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) open access Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors S. M. Batt, T. Jabeen, V. Bhowruth, L. Quill, P. A. Lund, L. Eggeling, L. J. Alderwick, K. Futterer, G. S. Besra
Proceedings Of The National Academy Of Sciences, 109 (28) Jul 2012 DOI: 10.1073/pnas.1205735109 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases Nathan Rose, Esther C. Y. Woon, Anthony Tumber, Louise J. Walport, Rasheduzzaman Chowdhury, Xuan Shirley Li, Oliver N. F. King, Clarisse Lejeune, Stanley Ng, Tobias Krojer, Mun Chiang Chan, Anna M. Rydzik, Richard J. Hopkinson, Ka Hing Che, Michelle Daniel, Claire Strain-Damerell, Carina Gileadi, Grazyna Kochan, Ivanhoe K. H. Leung, James Dunford, Kar Kheng Yeo, Peter J. Ratcliffe, Nicola Burgess-Brown, Frank Von Delft, Susanne Muller, Brian Marsden, Paul. E. Brennan, Michael A. Mcdonough, Udo Oppermann, Robert J. Klose, Christopher J. Schofield, Akane Kawamura
Journal Of Medicinal Chemistry, 55 (14) Jul 2012 DOI: 10.1021/jm300677j Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) The crystal structure of the extracellular 11-heme cytochrome UndA reveals a conserved 10-heme motif and defined binding site for soluble iron chelates Marcus J. Edwards, Andrea Hall, Liang Shi, James K. Fredrickson, John M. Zachara, Julea N. Butt, David J. Richardson, Thomas A. Clarke
Structure, 20 (7) Jul 2012 DOI: 10.1016/j.str.2012.04.016 Journal Paper I02-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography NF45 dimerizes with NF90, Zfr and SPNR via a conserved domain that has a nucleotidyltransferase fold Atlanta G. Cook, Urszula Wolkowicz
Nucleic Acids Research , 40 (18) Jul 2012 DOI: 10.1093/nar/gks696 Journal Paper I02-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) open access Structure of a murine norovirus NS6 protease-product complex revealed by adventitious crystallisation Eoin N. Leen, Gabriela Baeza, Stephen Curry
Plos One, 7 (6) June 2012 DOI: 10.1371/journal.pone.0038723 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) open access Expression, purification and crystallization of the Crimean-Congo haemorrhagic fever virus nucleocapsid protein S. D. Carter, J. N. Barr, T. A. Edwards
Acta Crystallographica Section F Structural Biology And Crystallization Communications, 68 (5) May 2012 DOI: 10.1107/S1744309112009736 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) 3'-Processing and strand transfer catalysed by retroviral integrase in crystallo Stephen Hare, Goedele N Maertens, Peter Cherepanov
The Embo Journal, 31 (13) May 2012 DOI: 10.1038/emboj.2012.118 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) open access Fast high-pressure freezing of protein crystals in their mother liquor Anja Burkhardt, Martin Warmer, Saravanan Panneerselvam, Armin Wagner, Athina Zouni, Carina Gloeckner, Rudolph Reimer, Heinrich Hohenberg, Alke Meents
Acta Crystallographica Section F Structural Biology And Crystallization Communications, 68 (4) Apr 2012 DOI: 10.1107/S1744309112009670 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family Panagis Filippakopoulos, Sarah Picaud, Oleg Fedorov, Marco Keller, Matthias Wrobel, Olaf Morgenstern, Franz Bracher, Stefan Knapp
Bioorganic & Medicinal Chemistry, 20 (6) Mar 2012 DOI: 10.1016/j.bmc.2011.10.080 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) open access Histone recognition and large-scale structural analysis of the human bromodomain family Panagis Filippakopoulos, Sarah Picaud, Maria Mangos, Tracy Keates, Jean-Philippe Lambert, Dalia Barsyte-Lovejoy, Ildiko Felletar, Rudolf Volkmer, Susanne Müller, Tony Pawson, Anne-Claude Gingras, Cheryl h. Arrowsmith, Stefan Knapp
Cell, 149 (1) Mar 2012 DOI: 10.1016/j.cell.2012.02.013 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access Structural insights into human Kif7, a kinesin involved in Hedgehog signalling Marta Klejnot, Frank Kozielski
Acta Crystallographica Section D Biological Crystallography, 68 (2) Jan 2012 DOI: 10.1107/S0907444911053042 Journal Paper I04-1-Macromolecular Crystallography (fixed wavelength) open access Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl Hao Dou, Lori Buetow, Andreas Hock, Gary J Sibbet, Karen H Vousden, Danny Huang
Nature Structural & Molecular Biology, 19 (2) Jan 2012 DOI: 10.1038/nsmb.2231 Journal Paper I02-Macromolecular Crystallography I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) Structural and mechanistic insight into N-glycan processing by endo- -mannosidase Andrew Thompson, Rohan J. Williams, Zalihe Hakki, Dominic S. Alonzi, Tom Wennekes, Tracey Gloster, Kriangsak Songsrirote, Jane E. Thomas-Oates, Tanja M. Wrodnigg, Josef Spreitz, Arnold E. Stutz, Terry D. Butters, Spencer J. Williams, Gideon J. Davies
Proceedings Of The National Academy Of Sciences, Jan 2012 DOI: 10.1073/pnas.1111482109 Journal Paper I03-Macromolecular Crystallography I04-1-Macromolecular Crystallography (fixed wavelength) I24-Microfocus Macromolecular Crystallography open access Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands Gavin W. Collie, Rossella Promontorio, Sonja M. Hampel, Marialuisa Micco, Stephen Neidle, Gary N. Parkinson
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