IR spectroscopy is a widely used and versatile method for analysis at the molecular scale.
In fact single molecular species are identified, and their amount quantified, by specific vibrational spectra with several characteristic absorption bands in the mid-IR range.
The high information content of such spectra lends itself to the operation of data bases and the "fingerprint" approach especially to organic and biological material identification, as well as condensed matter studies.
IR Microspectroscopy allows not only molecular identification but also spatial resolution, which is necessary to the understanding of the physical-chemical properties of the vast range of materials and surfaces that are organised on a microstructural level. These include biomedical samples like tissue or single cells that can be mapped in plots showing molecular composition versus position by IR imaging technique.
The high brightness and small spot size available on using synchrotron radiation source make experiments possible at the highest spatial resolution and over a wide spectral range spanning from from hard X-rays to the far-IR. In particular, the combination of IR with X-ray microspectroscopy techniques at the same SR facility easily allows the complementary characterization of samples both at molecular and atomic levels.
High pressure analysis of pharmaceutical products, analysis and development of novel catalysts, studies of advanced materials, cancer screening and medical diagnostics, chemical imaging of industrially important polymer structures, biomineralisation, studies of ancient artefacts, analysing processed food products and investigating airborne and waterborne pollutants.
MIRIAM (Multimode InfraRed Imaging And Microspectroscopy) provides a brilliant and versatile microprobe for high resolution imaging of molecular structures as well as high sensitivity vibrational spectroscopy via FTIR up to the THz range. Experiments span from biomedical applications to physical-chemical researches.More information
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
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