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Nanoparticles (NP) are used in different applications such as cosmetics and medicine. To assess potential toxic effects and to design NP-based drug delivery systems it is critical to understand what happens to proteins upon interaction with these special particles. This information is difficult to obtain, but for the first time we have shown that using the B23 beamline, it is possible to detect and analyze structural changes of proteins in protein-metallic nanoparticle complexes1. By using ...
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DNA is, besides displaying its central biological role as bearer of the genetic material, an extremely versatile construction material. DNA has become very attractive for the creation of novel nanosized objects. We are studying the influence of modifications of DNA with the aim to create functional DNA based nano-materials. Our modifications generally consist of large chromophores, which show specific light-induced activity such as energy or electron transfer. We are using modifications ...
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The three dimensional structure (i.e. conformation) of natural proteins and peptides plays an important role in their biological activity and has led to the development of non-natural backbones which mimic such conformations and offers therapeutic advantages. Peptoids are peptidomimetics where the chemical modification is responsible for desirable chemical, physical and biological properties. The presence of tertiary amides in the peptoid backbone results in complex NMR spectra due to ...
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Diamond welcomes today’s news that the Engineering and Physical Sciences Research Council (EPSRC) is investing £12.9 million in the UK Catalysis Hub. Catalysis science is critical for the country’s chemical, energy, pharmaceutical, food, personal care and materials sectors.
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The coupled magnetic and electronic properties of rare-earth doped GaN semiconductors have attracted a lot of interest by researchers from industry and academia in recent years. Researchers from University of Strathclyde, Osaka University (Japan) and Diamond Light Source have investigated Eu-doped GaN at Diamond beamlines B18 and I06. Their results have been published in Nature’s Scientific Reports.
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The coupled magnetic and electronic properties of rare-earth doped GaN semiconductors have attracted a lot of interest by researchers from industry and academia in recent years. Researchers from University of Strathclyde, Osaka University (Japan) and Diamond Light Source have investigated Eu-doped GaN at Diamond beamlines B18 and I06. Their results have been published in Nature’s Scientific Reports.
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The properties of nanocrystalline materials, where crystallinity is limited to particles of a few nanometres in dimension, are heavily researched in a number of contemporary areas. This is because once the crystal is reduced to such a small size, the properties may change dramatically from the bulk material. The structure of the surface atomic arrangement also becomes a significant proportion of the total structure, which may change the reactivity of the material in a nanocrystalline form. ...
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STFC have just announced the next Public Engagement Fellowships Scheme. For researchers with good communication skills who have demonstrated a track record in public engagement with research or communication work.
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High-energy X-rays produced by Diamond Light Source, the UK's national synchrotron science facility, have revealed the earliest rugose coral recorded to date. Using high-resolution tomography enabled by the Diamond synchrotron, researchers from Amgueddfa Cymru – National Museum Wales and Golestan University (Iran) were able to create 3D images of the rare fossil, without having to sample it destructively.
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The impressive appearance of the second largest Gothic cathedral in Northern Europe, York Minster, has dominated the townscape since medieval times (Figure 1). Representing the architectural expression of developing Christianity during that period, its international historical significance is unquestioned, and the Minster has provided a source of inspiration for scholars through the ages. However, recent centuries have seen conservationists battling to preserve the authenticity of this ...
