B21 is a dedicated solution state Small Angle X-ray Scattering (SAXS) beamline with an emphasis on providing an optimised experimental setup for measuring scattering from biological samples. iNEXT and Instruct users can access this through our mail-in service described below.
Why use bio-SAXS?
The technique provides a rapid way to obtain low resolution structural data which in some cases can complement or add to data from other techniques such as MX and Cryo-EM. Other uses include understanding subunit arrangement in larger macromolecular complexes and observation of protein- or ligand-induced conformational changes.
What is mail-in bio-SAXS?
You mail your samples to us in specially prepared B21 sample containers, and choose from two data collection methods:
The data collection results are available immediately online using the ISPyB database. Additional mail-in containers are shipped back together with a report. Mail-in SAXS services include both SEC-SAXS and batch-mode. Mail-in SEC-SAXS users can specify Superdex 200, Superose 6, or the Shodex series of columns (KW-402, -403, -404, -405).
For further details see the B21 webpages here.
Dr Nathan Cowieson: firstname.lastname@example.org
Mr Nikul Khunti: email@example.com
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