Small Angle Scattering (SAXS)

Small Angle X-ray Scattering (SAXS) covers the major disciplines of Biology, Chemistry and Physics delivering structural and dynamic information in nanoscience, mesoscopic architectures, supramolecular structures and nucleation/growth of crystals. SAXS is also proving important in archaeological, environmental and conservation sciences,  indicating an ability to span a wide range of scientific disciplines.

Diamond has two beamlines dedicated to SAXS I22 and B21 but several others that carry out SAXS experiments from time to time, I12 (high energy SAXS, 50 - 150 KeV) and I07 (GiSAXS).

Post-Doc post combining SAXS and Tomography

As part of an international EPSRC-funded project (Tomo-SAXS) between QMUL, UCL, UoM, Diamond and ESRF, SEMS is seeking to appoint a Postdoctoral Research Assistant to couple synchrotron small-angle X-ray scattering (SAXS) and phase-contrast micro-tomography (pCT) to enable 3D imaging of fibrillar collagenous tissue in joints and intervertebral discs (IVD). The bioengineering challenge is to determine the correlated 3D deformation and structural changes at the molecular-, fibrillar-, and cell-matrix length-scales under physiological load in intact tissue, and how these alter in ageing, injury and disease. The post will be solely based on the Harwell Campus.

Postdoctoral Research Assistant - QMUL24137, see https://tinyurl.com/y4y3lcrw

Software Improvements

Dawn, with these tools, can be downloaded from www.dawnsci.org. The latest release of Dawn, includes an extensive set of data reduction tools for SAXS data. A detailed description of these tools can be found in the recent paper by Pauw et al. A paper concerning the processing perspective available in Dawn has been published recently and has been highlighted on the Diamond website.

New to SAXS?

  • The Beginners Guide to SAXS provides useful information on what is possible, helpful hints and tips for experiments and some basic background on our beamlines, I22 and B21. The Beginners guide also includes a useful reference book list for Small Angle Scattering.
  • A nice introduction to the technique was been printed in the 2015 issue of our "Inside Diamond" Magazine. You can find it on pages 20-21 of the magazine.

Protein Nanocage under pressure

Beamline Image

There are many drugs that are not in clinical use because they are either too toxic or too ...

Diamond Light Source

Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.

Copyright © 2020 Diamond Light Source

 

Diamond Light Source Ltd
Diamond House
Harwell Science & Innovation Campus
Didcot
Oxfordshire
OX11 0DE

See on Google Maps

Diamond Light Source® and the Diamond logo are registered trademarks of Diamond Light Source Ltd