Katsuaki Inoue

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Katsuaki Inoue is Senior Beamline Scientist for the solution state SAXS beamline B21.

Email: katsuaki.inoue@diamond.ac.uk
Tel: +44 (0)1235 77 8863

Dr Katsuaki Inoue obtained his PhD from Graduate School of Science, Hiroshima University in Japan. Katsuaki has joined SPring-8, the 3rd generation synchrotron facility in Japan, in 1997. After spending 2 years as a postdoctoral research associate in RIKEN, he has got a beamline scientist position at Japan Synchrotron Research Institute (JASRI) and completed the construction of 2 SAXS beamlines and has been in charge them. Along with the beamline jobs, he has developed his skills and knowledge on the structural analysis of protein molecules with SAXS. He moved to the UK in 2008 and joined B21 team as a senior beamline scientist.      

Dr Inoue’s research interests focus on elucidating the relationship between the function and the structure of biological molecules. He has also studied kinetics at Hiroshima University and has many experiences on developing special equipment for the kinetic study. Along with SAXS studies on protein molecules, he is also currently undertaking the research with Diffracted X-ray Tracking technique.

Biophysical Characterizations in the Solution State” R. P. Rambo and K. Inoue Encyclopedia of Virology, 4th Edition, Volume 1 191–198doi:10.1016/B978-0-12-814515-9.00107-7

“Design of a multipurpose sample cell holder for the Diamond Light Source high-throughput SAXS beamline B21” C. J. C. Edwards-Gayle, N. Khunti, I. W. Hamley, K. Inoue, N. Cowieson and R. RamboJournal of Synchrotron Radiation (2021) 28 318-321. doi: 10.1107/S1600577520013831

“A common SNP risk variant MT1-MMP causative for Dupuytren’s disease has a specific defect in collagenolytic activity”Y. Itoh, M. Ng, A. Wiberg, K. Inoue, N. Hirata, K, B. S. Pavia, N. Ito, K. Dzobo, N. Sato, V. Gifford, Y. Fujita, M. Inada and D. Furniss Matrix Biology (2021) 97 20-39doi: 10.1016/j.matbio.2021.02.003

“Beamline B21: high-throughput small-angle X-ray scattering at Diamond Light Source”N. P. CowiesonC. J. C. Edwards-Gayle, K. Inoue, N. S. KhuntiJ. DoutchE. WilliamsS. DanielsG. PreeceN. A. KrumpaJ. P. SutterM. D. TullyN. J. Terrill and R. P. Rambo Journal of Synchrotron Radiation (2020) 27(5) 1438–1446 doi: 10.1107/S1600577520009960

“Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-β-synthase domain” A. Imamura, T. Okada, H. Mase, T. Otani, T. Kobayashi, M. Tamura, B. K. Kubata, K. Inoue, R. P. Rambo, S. Uchiyama, K. Ishii, S. Nishimura and T. Inui  Nature Communications (2020) 11, Article number: 1837 doi: 10.1038/s41467-020-15611-3

“Membrane Stability in the Presence of Methacrylate Esters”V. Yeh, A. Goode, G. Eastham, R. P. Rambo, K. Inoue, J. Doutch and B. B. Bonev Langmuir (2020), 36 9649-9657 doi: 10.1021/acs.langmuir.9b03759

“Hexameric assembly of AAA+ protein MCrB is necessary for GTPase activity” N. Nirwan, P. Singh, G. G. Mishra, C. M. Johnson, M. D. Szczelkun, K. Inoue, K. R. Vinothkumar and K. Saikrishnan Nucleic Acids Research (2019) 47(2) 868-882. doi: 10.1093/nar/gky1170

"Self-Assembly of the Cyclic Lipopeptide Daptomycin: Spherical Micelle Formation Does Not Depend on the Presence of Calcium Chloride"S. Kirkham, V. Castelletto, I.W. Hamley, K. Inoue, R. Rambo, M. Reza and J. Ruokolainen Chemphyschem. (2016) 17(14) 2118-22doi: 10.1002/cphc.201600308

“The Current Status of Small-Angle X-ray Scattering Beamline at Diamond Light Source” K. Inoue, J. Doutch and N. Terrill, BUNSEKI KAGAKU (2013) 62 565-570

“Drug delivery system for poorly water-soluble compounds using lipocalin-type prostaglandin D synthase”.A. Fukuhara, H. Nakajima, Y. Miyamoto, K. Inoue, S. Kume, Y. H. Lee, M. Noda, S. Uchiyama, S. Shimamoto, S. Nishimura, T. Ohkubo, Y Goto, T. Takeuchi and T. Inui Journal of Control Release (2012) 159 143-150

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