The effects of chain length on the structural properties of intrinsically disordered proteins in concentrated solutions Eric Fagerberg, Linda K. Månsson, Samuel Lenton, Marie Skepö
The Journal Of Physical Chemistry B, 124 Dec 2020 DOI: 10.1021/acs.jpcb.0c09635 Molecular characterization of the RNA-protein complex directing -2/-1 programmed ribosomal frameshifting during arterivirus replicase expression Ankoor Patel, Emmely E. Treffers, Markus Meier, Trushar R. Patel, Jörg Stetefeld, Eric J. Snijder, Brian L. Mark
Journal Of Biological Chemistry, 295 Dec 2020 DOI: 10.1074/jbc.RA120.016105 Structural analysis of the partially disordered protein EspK from Mycobacterium tuberculosis Abril Gijsbers, Nuria Sánchez-Puig, Ye Gao, Peter J. Peters, Raimond B. G. Ravelli, Dritan Siliqi
Crystals, 11 Dec 2020 DOI: 10.3390/cryst11010018 Design of a multipurpose sample cell holder for the Diamond Light Source high-throughput SAXS beamline B21 Charlotte Jennifer Chante Edwards-Gayle, Nikul Khunti, Ian W. Hamley, Katsuaki Inoue, Nathan Cowieson, Robert Rambo
Journal Of Synchrotron Radiation, 28 Dec 2020 DOI: 10.1107/S1600577520013831 Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa - decarboxylation is not essential for indole formation Annika Soderholm, Matilda S. Newton, Wayne M. Patrick, Maria Selmer
Journal Of Biological Chemistry, 295(47) Nov 2020 DOI: 10.1074/jbc.RA120.014936 Journal Paper B21-High Throughput SAXS I04-Macromolecular Crystallography open access Molecular changes in dengue envelope protein domain III upon interaction with glycosaminoglycans James G. Hyatt, Sylvain Prévost, Juliette M. Devos, Courtney J. Mycroft-West, Mark A. Skidmore, Anja Winter
Pathogens, 9 Nov 2020 DOI: 10.3390/pathogens9110935 Design of nanosystems for the delivery of quorum sensing inhibitors: A preliminary study Supandeep Singh Hallan, Paolo Marchetti, Daria Bortolotti, Maddalena Sguizzato, Elisabetta Esposito, Paolo Mariani, Claudio Trapella, Roberta Rizzo, Rita Cortesi
Molecules, 25 Nov 2020 DOI: 10.3390/molecules25235655 Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif Maria S. Eriksen, Oleksii Nikolaienko, Erik I. Hallin, Sverre Grødem, Helene J. Bustad, Marte I. Flydal, Ian Merski, Tomohisa Hosokawa, Daniela Lascu, Shreeram Akerkar, Jorge Cuellar, James J. Chambers, Rory O’connell, Gopinath Muruganandam, Remy Loris, Christine Touma, Tambudzai Kanhema, Yasunori Hayashi, Margaret M. Stratton, José M. Valpuesta, Petri Kursula, Aurora Martinez, Clive R. Bramham
The Febs Journal, 3 Nov 2020 DOI: 10.1111/febs.15618 Controlling protein nanocage assembly with hydrostatic pressure Kristian Le Vay, Ben M. Carter, Daniel W. Watkins, T.-Y. Dora Tang, Valeska P. Ting, Helmut Cölfen, Robert P. Rambo, Andrew J. Smith, J. L. Ross Anderson, Adam W. Perriman
Journal Of The American Chemical Society, Nov 2020 DOI: 10.1021/jacs.0c07285 Journal Paper B21-High Throughput SAXS B23-Circular Dichroism I22-Small angle scattering & Diffraction Light-responsive self-assembly of a cationic azobenzene surfactant at high concentration Camille Blayo, Elaine A. Kelly, Judith E. Houston, Nikul Khunti, Nathan P. Cowieson, Rachel C. Evans
Soft Matter, 56 Oct 2020 DOI: 10.1039/D0SM01512A SAXS reveals highly flexible interdomain linkers of tandem acyl carrier protein–thioesterase domains from a fungal non‐reducing polyketide synthase Waraporn Bunnak, Ashley J. Winter, Colin M. Lazarus, Matthew P. Crump, Paul R. Race, Pakorn Wattana‐amorn
Febs Letters, Oct 2020 DOI: 10.1002/1873-3468.13954 Structure-function studies of key amyloid-degrading enzymes Stephen Moss
Oct 2020 Thesis B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Controlling photocatalytic activity by self‐assembly – tuning perylene bisimide photocatalysts for the hydrogen evolution reaction Daniel Mcdowall, Benjamin J. Greeves, Rob Clowes, Kate Mcaulay, Ana M. Fuentes‐caparrós, Lisa Thomson, Nikul Khunti, Nathan Cowieson, Michael C. Nolan, Matthew Wallace, Andrew I. Cooper, Emily R. Draper, Alexander J. Cowan, Dave J. Adams
Advanced Energy Materials, 10 Oct 2020 DOI: 10.1002/aenm.202002469 Exploring conformational preferences of proteins: ionic liquid effects on the energy landscape of avidin Talia A. Shmool, Laura K. Martin, Coby J. Clarke, Liem Bui-Le, Karen M. Polizzi, Jason P. Hallett
Chemical Science, 5 Oct 2020 DOI: 10.1039/D0SC04991C Journal Paper B21-High Throughput SAXS B23-Circular Dichroism I22-Small angle scattering & Diffraction open access Solvent‐free liquid avidin as a step towards cold chain elimination Liem Bui-Le, Alex P. S. Brogan, Jason P. Hallett
Biotechnology And Bioengineering, Oct 2020 DOI: 10.1002/bit.27587 Journal Paper B21-High Throughput SAXS B23-Circular Dichroism I22-Small angle scattering & Diffraction open access Peptide-based gel in environmental remediation: removal of toxic organic dyes and hazardous Pb2+ and Cd2+ ions from wastewater and oil spill recovery Biplab Mondal, Dipayan Bairagi, Nibedita Nandi, Biswanath Hansda, Krishna Sundar Das, Charlotte J. C. Edwards-Gayle, Valeria Castelletto, Ian W. Hamley, Arindam Banerjee
Langmuir, Oct 2020 DOI: 10.1021/acs.langmuir.0c02205 Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases Chatrin Chatrin, Mads Gabrielsen, Lori Buetow, Mark A. Nakasone, Syed F. Ahmed, David Sumpton, Gary J. Sibbet, Brian O. Smith, Danny Huang
Science Advances, 6 Sept 2020 DOI: 10.1126/sciadv.abc0418 Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access Peptide nanotubes self-assembled from leucine-rich alpha helical surfactant-like peptides Valeria Castelletto, Jani Seitsonen, Janne Ruokolainen, Cristian Piras, Rainer Cramer, Charlotte J. C. Edwards-Gayle, Ian W. Hamley
Chemical Communications, 369 Sept 2020 DOI: 10.1039/D0CC04299D PFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin Rasmus Ree, Laura Kind, Anna Kaziales, Sylvia Varland, Minglu Dai, Klaus Richter, Adrian Drazic, Thomas Arnesen
Journal Of Biological Chemistry, Sept 2020 DOI: 10.1074/jbc.RA120.015468 Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility Fernando Sánchez-Sáez, Laura Gómez-H, Orla M. Dunne, Cristina Gallego-Páramo, Natalia Felipe-Medina, Manuel Sánchez-Martín, Elena Llano, Alberto M. Pendas, Owen R. Davies
Science Advances, 6 Sept 2020 DOI: 10.1126/sciadv.abb1660 Structure of a nucleotide pyrophosphatase/phosphodiesterase (NPP) from Euphorbia characias latex characterized by small-angle X-ray scattering: clues for the general organization of plant NPPs Annalaura Sabatucci, Francesca Pintus, Tiziana Cabras, Federica Vincenzoni, Mauro Maccarrone, Rosaria Medda, Enrico Dainese
Acta Crystallographica Section D Structural Biology, 76 Sept 2020 DOI: 10.1107/S2059798320010207 Structure of the human cation-independent mannose 6-phosphate/IGF2 receptor domains 7–11 uncovers the mannose 6-phosphate binding site of domain 9 Alice J. Bochel, Christopher Williams, Airlie J. Mccoy, Hans-Jürgen Hoppe, Ashley J. Winter, Ryan D. Nicholls, Karl Harlos, E. Yvonne Jones, Imre Berger, A. Bassim Hassan, Matthew P. Crump
Structure, Sept 2020 DOI: 10.1016/j.str.2020.08.002 Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography Beamline B21: high-throughput small-angle X-ray scattering at Diamond Light Source Nathan P. Cowieson, Charlotte J. C. Edwards-Gayle, Katsuaki Inoue, Nikul S. Khunti, James Doutch, Eugene Williams, Steven Daniels, Geoff Preece, Nicholas A. Krumpa, John P. Sutter, Mark D. Tully, Nick J. Terrill, Robert P. Rambo
Journal Of Synchrotron Radiation, 27 Sept 2020 DOI: 10.1107/S1600577520009960 Transglutaminase-mediated cross-linking of tropoelastin to fibrillin stabilises the elastin precursor prior to elastic fibre assembly Michael P. Lockhart-Cairns, Helena Newandee, Jennifer Thomson, Anthony S. Weiss, Clair Baldock, Anna Tarakanova
Journal Of Molecular Biology, Sept 2020 DOI: 10.1016/j.jmb.2020.08.023 Heterogeneous dynamics in partially disordered proteins Salla I. Virtanen, Anne M. Kiirikki, Kornelia M. Mikula, Hideo Iwaï, O. H. Samuli Ollila
Physical Chemistry Chemical Physics, 337 Sept 2020 DOI: 10.1039/D0CP03473H The architectural change of the shell forming block from linear to V-shaped accelerates micellar disassembly but slows the complete enzymatic degradation of the amphiphiles Merav Segal, Lihi Ozery, Gadi Slor, Shreyas Shankar Wagle, Tamara Ehm, Roy Beck, Roey J. Amir
Biomacromolecules, Aug 2020 DOI: 10.1021/acs.biomac.0c00882 Design and characterization of ethosomes for transdermal delivery of caffeic acid Supandeep Singh Hallan, Maddalena Sguizzato, Paolo Mariani, Rita Cortesi, Nicolas Huang, Fanny Simelière, Nicola Marchetti, Markus Drechsler, Tautgirdas Ruzgas, Elisabetta Esposito
Pharmaceutics, 12 Aug 2020 DOI: 10.3390/pharmaceutics12080740 Structural insight into the membrane targeting domain of the Legionella deAMPylase SidD Igor Tascon, Xiao Li, María Lucas, D’anna Nelson, Ander Vidaurrazaga, Yi-Han Lin, Adriana L. Rojas, Aitor Hierro, Matthias P. Machner
Plos Pathogens, 16 Aug 2020 DOI: 10.1371/journal.ppat.1008734 Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography open access Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism Gustavo A. Bezerra, William R. Foster, Henry J. Bailey, Kevin G. Hicks, Sven W. Sauer, Bianca Dimitrov, Thomas J. Mccorvie, Jürgen G. Okun, Jared Rutter, Stefan Kölker, Wyatt W. Yue
Iucrj, 7 Jul 2020 DOI: 10.1107/S205225252000696X Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography open access Isotopic control over self-assembly in supramolecular gels Kate Mcauley, Han Wang, Ana M. Fuentes-Caparros, Lisa Thomson, Nikul Khunti, Nathan P. Cowieson, Honggang Cui, Annela Seddon, Dave J. Adams
Langmuir, Jul 2020 DOI: 10.1021/acs.langmuir.0c01552 Synthesis of multilamellar walls vesicles polyelectrolyte surfactant complexes from pH-stimulated phase transition using microbial biosurfactants C. Seyrig, P. Le Griel, N. Cowieson, J. Perez, N. Baccile
Journal Of Colloid And Interface Science, Jul 2020 DOI: 10.1016/j.jcis.2020.07.021 Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate binding site Luca Martinelli, Athanasios Adamopoulos, Patrik Johansson, Paul T. Wan, Jenny Gunnarsson, Hongwei Guo, Helen Boyd, Noam Zelcer, Titia K. Sixma
Journal Of Biological Chemistry, Jul 2020 DOI: 10.1074/jbc.RA120.014349 Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties Giuditta Dal Cortivo, Valerio Marino, Francesco Boni, Mario Milani, Daniele Dell'Orco
Biochimica Et Biophysica Acta (bba) - Molecular Cell Research, Jul 2020 DOI: 10.1016/j.bbamcr.2020.118794 Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ Sudeep Karki, Alexander V. Shkumatov, Sungwon Bae, Hyeonho Kim, Jaewon Ko, Tommi Kajander
Scientific Reports, 10 Jul 2020 DOI: 10.1038/s41598-020-68502-4 Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography open access Natural killer cell activation receptor NKP30 oligomerization depends on its n-glycosylation Ondřej Skořepa, Samuel Pazicky, Barbora Kalousková, Jan Bláha, Celeste Abreu, Tomáš Ječmen, Michal Rosůlek, Alexander Fish, Arthur Sedivy, Karl Harlos, Jan Dohnalek, Tereza Skálová, Ondřej Vaněk
Cancers, 12 Jul 2020 DOI: 10.3390/cancers12071998 Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography open access Architecture and functional dynamics of the pentafunctional AROM complex Harshul Arora Verasztó, Maria Logotheti, Reinhard Albrecht, Alexander Leitner, Hongbo Zhu, Marcus D. Hartmann
Nature Chemical Biology, 64 Jul 2020 DOI: 10.1038/s41589-020-0587-9 Dissecting the structural and chemical determinants of the 'open-to-closed' motion in the mannosyltransferase PimA from mycobacteria Ane Rodrigo-Unzueta, Mattia Ghirardello, Saioa Urresti, Ignacio Delso, David Giganti, Itxaso Anso, Beatriz Trastoy, Natalia Comino, Montse Tersa, Cecilia D'Angelo, Javier O. Cifuente, Alberto Marina, Jobst Liebau, Lena Mäler, Alexandre Chenal, David Albesa-Jove, Pedro Merino, Marcelo E. Guerin
Biochemistry, Jul 2020 DOI: 10.1021/acs.biochem.0c00376 Stimuli-induced nonequilibrium phase transitions in polyelectrolyte–surfactant complex coacervates Chloe Seyrig, Gertrude Kignelman, Wim Thielemans, Patrick Le Griel, Nathan Cowieson, Javier Perez, Niki Baccile
Langmuir, Jul 2020 DOI: 10.1021/acs.langmuir.0c01177 Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release Henry J. Bailey, Gustavo A. Bezerra, Jason R. Marcero, Siladitya Padhi, William R. Foster, Elzbieta Rembeza, Arijit Roy, David F. Bishop, Robert J. Desnick, Gopalakrishnan Bulusu, Harry A. Dailey, Wyatt W. Yue
Nature Communications, 11 June 2020 DOI: 10.1038/s41467-020-16586-x Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access The dual PDZ domain from Postsynaptic density protein 95 forms a scaffold with peptide ligand N. A. Rodzli, M. P. Lockhart-Cairns, C. W. Levy, J. Chipperfield, L. Bird, C. Baldock, S. M. Prince
Biophysical Journal, June 2020 DOI: 10.1016/j.bpj.2020.06.018 Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access Ethosomes for coenzyme Q10 cutaneous administration: From design to 3D skin tissue evaluation Maddalena Sguizzato, Paolo Mariani, Francesco Spinozzi, Mascia Benedusi, Franco Cervellati, Rita Cortesi, Markus Drechsler, Roxane Prieux, Giuseppe Valacchi, Elisabetta Esposito
Antioxidants, 9 June 2020 DOI: 10.3390/antiox9060485 Methionine-rich loop of multicopper oxidase McoA follows open-to-close transitions with a role in enzyme catalysis Patricia Borges, Vânia Brissos, Guillem Hernandez, Laura Masgrau, Maria Fátima Lucas, Emanuele Monza, Carlos Frazao, Tiago Cordeiro, Lígia O. Martins
Acs Catalysis, June 2020 DOI: 10.1021/acscatal.0c01623 Structure, dynamics and cellular insight into novel substrates of the Legionella pneumophila type II secretion system Theo J. Portlock, Jessica Y. Tyson, Sarath C. Dantu, Saima Rehman, Richard C. White, Ian E. Mcintire, Lee Sewell, Katherine Richardson, Rosie Shaw, Alessandro Pandini, Nicholas P. Cianciotto, James Garnett
Frontiers In Molecular Biosciences, 7 June 2020 DOI: 10.3389/fmolb.2020.00112 Journal Paper B21-High Throughput SAXS I04-Macromolecular Crystallography open access Revealing the complexity of ionic liquid–protein interactions through a multi-technique investigation Liem Bui-Le, Coby J. Clarke, Andreas Brohl, Alex P. S. Brogan, James A. J. Arpino, Karen M. Polizzi, Jason P. Hallett
Communications Chemistry, 3 May 2020 DOI: 10.1038/s42004-020-0302-5 Journal Paper B21-High Throughput SAXS B23-Circular Dichroism open access Structural and hydrodynamic characterization of dimeric human oligoadenylate synthetase 2 Amit Koul, Darren Gemmill, Nikhat Lubna, Markus Meier, Natalie Krahn, Evan P. Booy, Jörg Stetefeld, Trushar R. Patel, Sean A. Mckenna
Biophysical Journal, May 2020 DOI: 10.1016/j.bpj.2020.04.025 Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation Saima Rehman, Lubov S. Grigoryeva, Katherine H. Richardson, Paula Corsini, Richard C. White, Rosie Shaw, Theo J. Portlock, Benjamin Dorgan, Zeinab S. Zanjani, Arianna Fornili, Nicholas P. Cianciotto, James Garnett
Plos Pathogens, 16 May 2020 DOI: 10.1371/journal.ppat.1008342 Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography I04-Macromolecular Crystallography open access Purification and structural characterization of aggregation-prone human TDP-43 involved in neurodegenerative diseases Gareth S. A. Wright, Tatiana F. Watanabe, Kangsa Amporndanai, Steven S. Plotkin, Neil R. Cashman, Svetlana V. Antonyuk, S. Samar Hasnain
Iscience, May 2020 DOI: 10.1016/j.isci.2020.101159 Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography open access Chain-end modifications and sequence arrangements of antimicrobial peptoids for mediating activity and nano-assembly Abshar Hasan, Varun Saxena, Valeria Castelletto, Georgina Zimbitas, Jani Seitsonen, Janne Ruokolainen, Lalit M. Pandey, Jan Sefcik, Ian W. Hamley, King Hang Aaron Lau
Frontiers In Chemistry, 8 May 2020 DOI: 10.3389/fchem.2020.00416 Isotype switching converts anti-CD40 antagonism to agonism to elicit potent antitumor activity Xiaojie Yu, H.t. Claude Chan, Hayden Fisher, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Vikki English, J. Sjef Verbeek, Ann L. White, Ivo Tews, Martin J. Glennie, Mark S. Cragg
Cancer Cell, May 2020 DOI: 10.1016/j.ccell.2020.04.013 Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2 Leanne Milton-Harris, Mark Jeeves, Sarah A. Walker, Simon E. Ward, Erika J. Mancini
Oncotarget, 11 May 2020 DOI: 10.18632/oncotarget.27580 Nanoparticulate gels for cutaneous administration of caffeic acid Maddalena Sguizzato, Paolo Mariani, Francesca Ferrara, Markus Drechsler, Supandeep Singh Hallan, Nicolas Huang, Fanny Simelière, Nikul Khunti, Rita Cortesi, Nicola Marchetti, Giuseppe Valacchi, Elisabetta Esposito
Nanomaterials, 10 May 2020 DOI: 10.3390/nano10050961 Diamond’s 9000th publication: green materials for thermal energy storage Diamond Light Source
May 2020 Science Highlight B21-High Throughput SAXS
Magnetic field-induced alignment of nanofibrous supramolecular membranes: a molecular design approach to create tissue-like biomaterials Elham Radvar, Yejiao Shi, Salvatore Grasso, Charlotte J. C. Edwards-Gayle, Xitong Liu, Meagan S. Mauter, Valeria Castelletto, Ian W. Hamley, Michael J. Reece, Helena S. Azevedo
Acs Applied Materials & Interfaces, Apr 2020 DOI: 10.1021/acsami.0c05191 Pyocin s5 import into Pseudomonas aeruginosa reveals a generic mode of bacteriocin transport Hannah M. Behrens, Edward D. Lowe, Joseph Gault, Nicholas G. Housden, Renata Kaminska, T. Moritz Weber, Catriona M. A. Thompson, Gaëtan L. A. Mislin, Isabelle J. Schalk, Daniel Walker, Carol V. Robinson, Colin Kleanthous
Mbio, 11 Apr 2020 DOI: 10.1128/mBio.03230-19 Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-β-synthase domain Akira Imamura, Tetsuya Okada, Hikaru Mase, Takuya Otani, Tomoka Kobayashi, Manatsu Tamura, Bruno Kilunga Kubata, Katsuaki Inoue, Robert P. Rambo, Susumu Uchiyama, Kentaro Ishii, Shigenori Nishimura, Takashi Inui
Nature Communications, 11 Apr 2020 DOI: 10.1038/s41467-020-15611-3 The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Jingjing Zhang, Manickam Gurusaran, Yasuhiro Fujiwara, Kexin Zhang, Meriem Echbarthi, Egor Vorontsov, Rui Guo, Devon F. Pendlebury, Intekhab Alam, Gabriel Livera, Martini Emmanuelle, P. Jeremy Wang, Jayakrishnan Nandakumar, Owen Davies, Hiroki Shibuya
Nature Communications, 11 Apr 2020 DOI: 10.1038/s41467-020-15954-x Colloidal features of softwood galactoglucomannans-rich extract Mamata Bhattarai, Irina Sulaeva, Leena Pitkänen, Inkeri Kontro, Maija Tenkanen, Antje Potthast, Kirsi S. Mikkonen
Carbohydrate Polymers, Apr 2020 DOI: 10.1016/j.carbpol.2020.116368 Self-assembled gold nanoparticles and amphiphile peptides: a colorimetric probe for copper( ii ) ion detection Juliane N. B. D. Pelin, Charlotte J. C. Edwards-Gayle, Herculano Martinho, Barbara B. Gerbelli, Valeria Castelletto, Ian W. Hamley, Wendel A. Alves
Dalton Transactions, 53 Apr 2020 DOI: 10.1039/D0DT00844C Modulating the release of pharmaceuticals from lipid cubic phases using a lipase inhibitor Michele Dully, Christopher Brasnett, Ahmed Djeghader, Annela Seddon, John Neilan, David Murray, James Butler, Tewfik Soulimane, Sarah P. Hudson
Journal Of Colloid And Interface Science, Apr 2020 DOI: 10.1016/j.jcis.2020.04.015 Polymorphism of asymmetric catalysts based on amphiphilic lipopeptides in solution Juliane N. B. D. Pelin, Charlotte J. C. Edwards-Gayle, Andrea Aguilar, Amanpreet Kaur, Ian W. Hamley, Wendel A. Alves
Soft Matter, Apr 2020 DOI: 10.1039/D0SM00245C Molecular flexibility of DNA as a key determinant of RAD 51 recruitment Federico Paoletti, Afaf H. El-Sagheer, Jun Allard, Tom Brown, Omer Dushek, Fumiko Esashi
The Embo Journal, 39 Apr 2020 DOI: 10.15252/embj.2019103002 Lignin-fatty acid hybrid nanocapsules for scalable thermal energy storage in phase-change materials Mika H. Sipponen, Alexander Henn, Paavo Penttilä, Monika Österberg
Chemical Engineering Journal, Mar 2020 DOI: 10.1016/j.cej.2020.124711 Self-assembly, nematic phase formation, and organocatalytic behavior of a proline-functionalized lipopeptide Juliane N. B. D. Pelin, Charlotte J. C. Edwards-Gayle, Valeria Castelletto, Andrea M. Aguilar, Wendel A. Alves, Jani Seitsonen, Janne Ruokolainen, Ian W. Hamley
Acs Applied Materials & Interfaces, Mar 2020 DOI: 10.1021/acsami.0c00686 A single-component photorheological fluid with light-responsive viscosity Elaine A. Kelly, Niamh Willis-Fox, Judith E. Houston, Camille Blayo, Giorgio Divitini, Nathan Cowieson, Ronan Daly, Rachel C. Evans
Nanoscale, 12 Mar 2020 DOI: 10.1039/C9NR10350C Amyloid peptide mixtures: self-assembly, hydrogelation, nematic ordering, and catalysts in aldol reactions Juliane N. B. D. Pelin, Barbara B. Gerbelli, Charlotte J. C. Edwards-Gayle, Andrea M. Aguilar, Valeria Castelletto, Ian W. Hamley, Wendel A. Alves
Langmuir, Mar 2020 DOI: 10.1021/acs.langmuir.0c00198 Controlling the properties of the micellar and gel phase by varying the counterion in functionalised-dipeptide systems Kate Mcaulay, Pedro Agís Ucha, Han Wang, Ana M. Fuentes-Caparros, Lisa Thomson, Osama Maklad, Nikul Khunti, Nathan Cowieson, Matthew Wallace, Honggang Cui, Robert J. Poole, Annela Seddon, Dave J. Adams
Chemical Communications, 97 Mar 2020 DOI: 10.1039/D0CC01252A Functional homo- and heterodimeric actin capping proteins from the malaria parasite Abris Adam Bendes, Moon Chatterjee, Benjamin Götte, Petri Kursula, Inari Kursula
Biochemical And Biophysical Research Communications, Mar 2020 DOI: 10.1016/j.bbrc.2020.02.119 The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture Catherine R. Back, Victoria A. Higman, Kristian Levay, Viren V. Patel, Alice E. Parnell, Daniel Frankel, Howard F. Jenkinson, Steven G. Burston, Matthew P. Crump, Angela H. Nobbs, Paul R. Race
Journal Of Biological Chemistry, Mar 2020 DOI: 10.1074/jbc.RA119.011719 Ellagic acid containing nanostructured lipid carriers for topical application: a preliminary study Supandeep Singh Hallan, Maddalena Sguizzato, Gabriella Pavoni, Anna Baldisserotto, Markus Drechsler, Paolo Mariani, Elisabetta Esposito, Rita Cortesi
Molecules, 25 Mar 2020 DOI: 10.3390/molecules25061449 Membrane stability in the presence of methacrylate esters Vivien Yeh, Alice Goode, Graham Eastham, Robert P. Rambo, Katsuaki Inoue, James Doutch, Boyan B. Bonev
Langmuir, Mar 2020 DOI: 10.1021/acs.langmuir.9b03759 Conformation and phase behavior of sodium carboxymethyl cellulose in the presence of mono- and divalent salts William N. Sharratt, Róisín O’connell, Sarah E. Rogers, Carlos G. Lopez, Joao T. Cabral
Macromolecules, Feb 2020 DOI: 10.1021/acs.macromol.9b02228 Phosphorylation of a disordered peptide – structural effects and force field inconsistencies Ellen Rieloff, Marie Skepö
Journal Of Chemical Theory And Computation, Feb 2020 DOI: 10.1021/acs.jctc.9b01190 Mechanism of crosstalk between the LSD1 demethylase and HDAC1 deacetylase in the CoREST complex Yun Song, Lisbeth Dagil, Louise Fairall, Naomi Robertson, Mingxuan Wu, T. J. Ragan, Christos G. Savva, Almutasem Saleh, Nobuhiro Morone, Micha B. A. Kunze, Andrew G. Jamieson, Philip A. Cole, D. Flemming Hansen, John W. R. Schwabe
Cell Reports, 30 Feb 2020 DOI: 10.1016/j.celrep.2020.01.091 Journal Paper B21-High Throughput SAXS Krios I-Titan Krios I at Diamond open access Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein Lenka Stejskal, William D. Lees, David S. Moss, Machaela Palor, Richard J. Bingham, Adrian J. Shepherd, Joe Grove
Plos Computational Biology, 16 Feb 2020 DOI: 10.1371/journal.pcbi.1007710 Solution structure of the cytoplasmic domain of NhaP2 a K+/H+ antiporter from Vibrio cholera George L. Orriss, Vu To, Aniel Moya-Torres, Genevieve Seabrook, Joe O'Neil, Jörg Stetefeld
Biochimica Et Biophysica Acta (bba) - Biomembranes, Feb 2020 DOI: 10.1016/j.bbamem.2020.183225 Investigating the influence of solvent quality on RAFT-mediated PISA of sulfonate-functional diblock copolymer nanoparticles Shang-Pin Wen, Jack G. Saunders, Lee A. Fielding
Polymer Chemistry, 268 Feb 2020 DOI: 10.1039/C9PY01912J Oligomerization and characteristics of phosphoenolpyruvate carboxylase in Synechococcus PCC 7002 Claudia Durall De La Fuente, Sandesh Kanchugal Puttaswamy, Maria Selmer, Peter Lindblad
Scientific Reports, 10 Feb 2020 DOI: 10.1038/s41598-020-60249-2 Nanoscale structure determination of Murray Valley encephalitis and Powassan virus non-coding RNAs Tyler Mrozowich, Amy Henrickson, Borries Demeler, Trushar Patel
Viruses, 12 Jan 2020 DOI: 10.3390/v12020190 Multimeric antibodies with increased valency surpassing functional affinity and potency thresholds using novel formats Ami Miller, Stephen Carr, Terry Rabbitts, Hanif Ali
Mabs, 12 Jan 2020 DOI: 10.1080/19420862.2020.1752529 Solution structure and oligomeric state of the E. coli glycerol facilitator Mary Hernando, George Orris, Jacqueline Perodeau, Shixing Lei, Fraser G. Ferens, Trushar R. Patel, Jörg Stetefeld, Andrew J. Nieuwkoop, Joe D. O'Neil
Biochimica Et Biophysica Acta (bba) - Biomembranes, Jan 2020 DOI: 10.1016/j.bbamem.2020.183191 Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution Doo Nam Kim, Bernhard C. Thiel, Tyler Mrozowich, Scott P. Hennelly, Ivo L. Hofacker, Trushar R. Patel, Karissa Y. Sanbonmatsu
Nature Communications, 11 Jan 2020 DOI: 10.1038/s41467-019-13942-4 Selective antibacterial activity and lipid membrane interactions of arginine-rich amphiphilic peptides Charlotte J. C. Edwards-Gayle, Glyn Barrett, Shyamali Roy, Valeria Castelletto, Jani Seitsonen, Janne Ruokolainen, Ian W. Hamley
Acs Applied Bio Materials, Jan 2020 DOI: 10.1021/acsabm.9b00894 Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate Stephen Mcmahon, Wenlong Zhu, Shirley Graham, Robert Rambo, Malcolm F. White, Tracey M. Gloster
Nature Communications, 11 Jan 2020 DOI: 10.1038/s41467-019-14222-x Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) open access Supertertiary structure analysis and comparison of BET proteins upon bivalent binding Ailefeila Aihemaiti
Jan 2020 Thesis B21-High Throughput SAXS