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Soft Condensed Matter - Small Angle Scattering
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B21 Contact

Beamline phone numbers:
+44 (0) 1235 77 8627
+44 (0) 1235 77 8640

Principal Beamline Scientist: 
Nathan Cowieson

Tel: +44 (0) 1235 567 504
E-mail: [email protected]

More

Science Group Leader

Robert Rambo

Email: [email protected]
Tel: +44 (0)1235 56 7675

B21 High Throughput SAXS

Status: Operational

Beamsize: <75 μm
Detector: Eiger 4M
Energy: 6 - 23 keV

SAXS: Small Angle X-ray Scattering Humidity Control Remote Access Scattering
  1. Instruments
  2. Soft Condensed Matter
  3. Small Angle Scattering
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Publications

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84 items found for 2020 [total: 655]


The effects of chain length on the structural properties of intrinsically disordered proteins in concentrated solutions
Eric Fagerberg, Linda K. Månsson, Samuel Lenton, Marie Skepö
The Journal Of Physical Chemistry B, 124 Dec 2020 DOI: 10.1021/acs.jpcb.0c09635
Journal Paper B21-High Throughput SAXS open access
Molecular characterization of the RNA-protein complex directing -2/-1 programmed ribosomal frameshifting during arterivirus replicase expression
Ankoor Patel, Emmely E. Treffers, Markus Meier, Trushar R. Patel, Jörg Stetefeld, Eric J. Snijder, Brian L. Mark
Journal Of Biological Chemistry, 295 Dec 2020 DOI: 10.1074/jbc.RA120.016105
Journal Paper B21-High Throughput SAXS open access
Structural analysis of the partially disordered protein EspK from Mycobacterium tuberculosis
Abril Gijsbers, Nuria Sánchez-Puig, Ye Gao, Peter J. Peters, Raimond B. G. Ravelli, Dritan Siliqi
Crystals, 11 Dec 2020 DOI: 10.3390/cryst11010018
Journal Paper B21-High Throughput SAXS open access
Design of a multipurpose sample cell holder for the Diamond Light Source high-throughput SAXS beamline B21
Charlotte Jennifer Chante Edwards-Gayle, Nikul Khunti, Ian W. Hamley, Katsuaki Inoue, Nathan Cowieson, Robert Rambo
Journal Of Synchrotron Radiation, 28 Dec 2020 DOI: 10.1107/S1600577520013831
Journal Paper B21-High Throughput SAXS open access
Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa - decarboxylation is not essential for indole formation
Annika Soderholm, Matilda S. Newton, Wayne M. Patrick, Maria Selmer
Journal Of Biological Chemistry, 295(47) Nov 2020 DOI: 10.1074/jbc.RA120.014936
Journal Paper B21-High Throughput SAXS I04-Macromolecular Crystallography open access
Molecular changes in dengue envelope protein domain III upon interaction with glycosaminoglycans
James G. Hyatt, Sylvain Prévost, Juliette M. Devos, Courtney J. Mycroft-West, Mark A. Skidmore, Anja Winter
Pathogens, 9 Nov 2020 DOI: 10.3390/pathogens9110935
Journal Paper B21-High Throughput SAXS open access
Design of nanosystems for the delivery of quorum sensing inhibitors: A preliminary study
Supandeep Singh Hallan, Paolo Marchetti, Daria Bortolotti, Maddalena Sguizzato, Elisabetta Esposito, Paolo Mariani, Claudio Trapella, Roberta Rizzo, Rita Cortesi
Molecules, 25 Nov 2020 DOI: 10.3390/molecules25235655
Journal Paper B21-High Throughput SAXS open access
Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif
Maria S. Eriksen, Oleksii Nikolaienko, Erik I. Hallin, Sverre Grødem, Helene J. Bustad, Marte I. Flydal, Ian Merski, Tomohisa Hosokawa, Daniela Lascu, Shreeram Akerkar, Jorge Cuellar, James J. Chambers, Rory O’connell, Gopinath Muruganandam, Remy Loris, Christine Touma, Tambudzai Kanhema, Yasunori Hayashi, Margaret M. Stratton, José M. Valpuesta, Petri Kursula, Aurora Martinez, Clive R. Bramham
The Febs Journal, 3 Nov 2020 DOI: 10.1111/febs.15618
Journal Paper B21-High Throughput SAXS
Controlling protein nanocage assembly with hydrostatic pressure
Kristian Le Vay, Ben M. Carter, Daniel W. Watkins, T.-Y. Dora Tang, Valeska P. Ting, Helmut Cölfen, Robert P. Rambo, Andrew J. Smith, J. L. Ross Anderson, Adam W. Perriman
Journal Of The American Chemical Society, Nov 2020 DOI: 10.1021/jacs.0c07285
Journal Paper B21-High Throughput SAXS B23-Circular Dichroism I22-Small angle scattering & Diffraction
Light-responsive self-assembly of a cationic azobenzene surfactant at high concentration
Camille Blayo, Elaine A. Kelly, Judith E. Houston, Nikul Khunti, Nathan P. Cowieson, Rachel C. Evans
Soft Matter, 56 Oct 2020 DOI: 10.1039/D0SM01512A
Journal Paper B21-High Throughput SAXS open access
SAXS reveals highly flexible interdomain linkers of tandem acyl carrier protein–thioesterase domains from a fungal non‐reducing polyketide synthase
Waraporn Bunnak, Ashley J. Winter, Colin M. Lazarus, Matthew P. Crump, Paul R. Race, Pakorn Wattana‐amorn
Febs Letters, Oct 2020 DOI: 10.1002/1873-3468.13954
Journal Paper B21-High Throughput SAXS
Structure-function studies of key amyloid-degrading enzymes
Stephen Moss
Oct 2020
Thesis B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography
Controlling photocatalytic activity by self‐assembly – tuning perylene bisimide photocatalysts for the hydrogen evolution reaction
Daniel Mcdowall, Benjamin J. Greeves, Rob Clowes, Kate Mcaulay, Ana M. Fuentes‐caparrós, Lisa Thomson, Nikul Khunti, Nathan Cowieson, Michael C. Nolan, Matthew Wallace, Andrew I. Cooper, Emily R. Draper, Alexander J. Cowan, Dave J. Adams
Advanced Energy Materials, 10 Oct 2020 DOI: 10.1002/aenm.202002469
Journal Paper B21-High Throughput SAXS open access
Exploring conformational preferences of proteins: ionic liquid effects on the energy landscape of avidin
Talia A. Shmool, Laura K. Martin, Coby J. Clarke, Liem Bui-Le, Karen M. Polizzi, Jason P. Hallett
Chemical Science, 5 Oct 2020 DOI: 10.1039/D0SC04991C
Journal Paper B21-High Throughput SAXS B23-Circular Dichroism I22-Small angle scattering & Diffraction open access
Solvent‐free liquid avidin as a step towards cold chain elimination
Liem Bui-Le, Alex P. S. Brogan, Jason P. Hallett
Biotechnology And Bioengineering, Oct 2020 DOI: 10.1002/bit.27587
Journal Paper B21-High Throughput SAXS B23-Circular Dichroism I22-Small angle scattering & Diffraction open access
Peptide-based gel in environmental remediation: removal of toxic organic dyes and hazardous Pb2+ and Cd2+ ions from wastewater and oil spill recovery
Biplab Mondal, Dipayan Bairagi, Nibedita Nandi, Biswanath Hansda, Krishna Sundar Das, Charlotte J. C. Edwards-Gayle, Valeria Castelletto, Ian W. Hamley, Arindam Banerjee
Langmuir, Oct 2020 DOI: 10.1021/acs.langmuir.0c02205
Journal Paper B21-High Throughput SAXS
Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases
Chatrin Chatrin, Mads Gabrielsen, Lori Buetow, Mark A. Nakasone, Syed F. Ahmed, David Sumpton, Gary J. Sibbet, Brian O. Smith, Danny Huang
Science Advances, 6 Sept 2020 DOI: 10.1126/sciadv.abc0418
Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access
Peptide nanotubes self-assembled from leucine-rich alpha helical surfactant-like peptides
Valeria Castelletto, Jani Seitsonen, Janne Ruokolainen, Cristian Piras, Rainer Cramer, Charlotte J. C. Edwards-Gayle, Ian W. Hamley
Chemical Communications, 369 Sept 2020 DOI: 10.1039/D0CC04299D
Journal Paper B21-High Throughput SAXS open access
PFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin
Rasmus Ree, Laura Kind, Anna Kaziales, Sylvia Varland, Minglu Dai, Klaus Richter, Adrian Drazic, Thomas Arnesen
Journal Of Biological Chemistry, Sept 2020 DOI: 10.1074/jbc.RA120.015468
Journal Paper B21-High Throughput SAXS open access
Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility
Fernando Sánchez-Sáez, Laura Gómez-H, Orla M. Dunne, Cristina Gallego-Páramo, Natalia Felipe-Medina, Manuel Sánchez-Martín, Elena Llano, Alberto M. Pendas, Owen R. Davies
Science Advances, 6 Sept 2020 DOI: 10.1126/sciadv.abb1660
Journal Paper B21-High Throughput SAXS open access
Structure of a nucleotide pyrophosphatase/phosphodiesterase (NPP) from Euphorbia characias latex characterized by small-angle X-ray scattering: clues for the general organization of plant NPPs
Annalaura Sabatucci, Francesca Pintus, Tiziana Cabras, Federica Vincenzoni, Mauro Maccarrone, Rosaria Medda, Enrico Dainese
Acta Crystallographica Section D Structural Biology, 76 Sept 2020 DOI: 10.1107/S2059798320010207
Journal Paper B21-High Throughput SAXS
Structure of the human cation-independent mannose 6-phosphate/IGF2 receptor domains 7–11 uncovers the mannose 6-phosphate binding site of domain 9
Alice J. Bochel, Christopher Williams, Airlie J. Mccoy, Hans-Jürgen Hoppe, Ashley J. Winter, Ryan D. Nicholls, Karl Harlos, E. Yvonne Jones, Imre Berger, A. Bassim Hassan, Matthew P. Crump
Structure, Sept 2020 DOI: 10.1016/j.str.2020.08.002
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography
Beamline B21: high-throughput small-angle X-ray scattering at Diamond Light Source
Nathan P. Cowieson, Charlotte J. C. Edwards-Gayle, Katsuaki Inoue, Nikul S. Khunti, James Doutch, Eugene Williams, Steven Daniels, Geoff Preece, Nicholas A. Krumpa, John P. Sutter, Mark D. Tully, Nick J. Terrill, Robert P. Rambo
Journal Of Synchrotron Radiation, 27 Sept 2020 DOI: 10.1107/S1600577520009960
Journal Paper B21-High Throughput SAXS open access
Transglutaminase-mediated cross-linking of tropoelastin to fibrillin stabilises the elastin precursor prior to elastic fibre assembly
Michael P. Lockhart-Cairns, Helena Newandee, Jennifer Thomson, Anthony S. Weiss, Clair Baldock, Anna Tarakanova
Journal Of Molecular Biology, Sept 2020 DOI: 10.1016/j.jmb.2020.08.023
Journal Paper B21-High Throughput SAXS open access
Heterogeneous dynamics in partially disordered proteins
Salla I. Virtanen, Anne M. Kiirikki, Kornelia M. Mikula, Hideo Iwaï, O. H. Samuli Ollila
Physical Chemistry Chemical Physics, 337 Sept 2020 DOI: 10.1039/D0CP03473H
Journal Paper B21-High Throughput SAXS open access
The architectural change of the shell forming block from linear to V-shaped accelerates micellar disassembly but slows the complete enzymatic degradation of the amphiphiles
Merav Segal, Lihi Ozery, Gadi Slor, Shreyas Shankar Wagle, Tamara Ehm, Roy Beck, Roey J. Amir
Biomacromolecules, Aug 2020 DOI: 10.1021/acs.biomac.0c00882
Journal Paper B21-High Throughput SAXS open access
Design and characterization of ethosomes for transdermal delivery of caffeic acid
Supandeep Singh Hallan, Maddalena Sguizzato, Paolo Mariani, Rita Cortesi, Nicolas Huang, Fanny Simelière, Nicola Marchetti, Markus Drechsler, Tautgirdas Ruzgas, Elisabetta Esposito
Pharmaceutics, 12 Aug 2020 DOI: 10.3390/pharmaceutics12080740
Journal Paper B21-High Throughput SAXS open access
Structural insight into the membrane targeting domain of the Legionella deAMPylase SidD
Igor Tascon, Xiao Li, María Lucas, D’anna Nelson, Ander Vidaurrazaga, Yi-Han Lin, Adriana L. Rojas, Aitor Hierro, Matthias P. Machner
Plos Pathogens, 16 Aug 2020 DOI: 10.1371/journal.ppat.1008734
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography open access
Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism
Gustavo A. Bezerra, William R. Foster, Henry J. Bailey, Kevin G. Hicks, Sven W. Sauer, Bianca Dimitrov, Thomas J. Mccorvie, Jürgen G. Okun, Jared Rutter, Stefan Kölker, Wyatt W. Yue
Iucrj, 7 Jul 2020 DOI: 10.1107/S205225252000696X
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography open access
Isotopic control over self-assembly in supramolecular gels
Kate Mcauley, Han Wang, Ana M. Fuentes-Caparros, Lisa Thomson, Nikul Khunti, Nathan P. Cowieson, Honggang Cui, Annela Seddon, Dave J. Adams
Langmuir, Jul 2020 DOI: 10.1021/acs.langmuir.0c01552
Journal Paper B21-High Throughput SAXS open access
Synthesis of multilamellar walls vesicles polyelectrolyte surfactant complexes from pH-stimulated phase transition using microbial biosurfactants
C. Seyrig, P. Le Griel, N. Cowieson, J. Perez, N. Baccile
Journal Of Colloid And Interface Science, Jul 2020 DOI: 10.1016/j.jcis.2020.07.021
Journal Paper B21-High Throughput SAXS
Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate binding site
Luca Martinelli, Athanasios Adamopoulos, Patrik Johansson, Paul T. Wan, Jenny Gunnarsson, Hongwei Guo, Helen Boyd, Noam Zelcer, Titia K. Sixma
Journal Of Biological Chemistry, Jul 2020 DOI: 10.1074/jbc.RA120.014349
Journal Paper B21-High Throughput SAXS open access
Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties
Giuditta Dal Cortivo, Valerio Marino, Francesco Boni, Mario Milani, Daniele Dell'Orco
Biochimica Et Biophysica Acta (bba) - Molecular Cell Research, Jul 2020 DOI: 10.1016/j.bbamcr.2020.118794
Journal Paper B21-High Throughput SAXS
Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ
Sudeep Karki, Alexander V. Shkumatov, Sungwon Bae, Hyeonho Kim, Jaewon Ko, Tommi Kajander
Scientific Reports, 10 Jul 2020 DOI: 10.1038/s41598-020-68502-4
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography open access
Natural killer cell activation receptor NKP30 oligomerization depends on its n-glycosylation
Ondřej Skořepa, Samuel Pazicky, Barbora Kalousková, Jan Bláha, Celeste Abreu, Tomáš Ječmen, Michal Rosůlek, Alexander Fish, Arthur Sedivy, Karl Harlos, Jan Dohnalek, Tereza Skálová, Ondřej Vaněk
Cancers, 12 Jul 2020 DOI: 10.3390/cancers12071998
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography open access
Architecture and functional dynamics of the pentafunctional AROM complex
Harshul Arora Verasztó, Maria Logotheti, Reinhard Albrecht, Alexander Leitner, Hongbo Zhu, Marcus D. Hartmann
Nature Chemical Biology, 64 Jul 2020 DOI: 10.1038/s41589-020-0587-9
Journal Paper B21-High Throughput SAXS
Dissecting the structural and chemical determinants of the 'open-to-closed' motion in the mannosyltransferase PimA from mycobacteria
Ane Rodrigo-Unzueta, Mattia Ghirardello, Saioa Urresti, Ignacio Delso, David Giganti, Itxaso Anso, Beatriz Trastoy, Natalia Comino, Montse Tersa, Cecilia D'Angelo, Javier O. Cifuente, Alberto Marina, Jobst Liebau, Lena Mäler, Alexandre Chenal, David Albesa-Jove, Pedro Merino, Marcelo E. Guerin
Biochemistry, Jul 2020 DOI: 10.1021/acs.biochem.0c00376
Journal Paper B21-High Throughput SAXS
Stimuli-induced nonequilibrium phase transitions in polyelectrolyte–surfactant complex coacervates
Chloe Seyrig, Gertrude Kignelman, Wim Thielemans, Patrick Le Griel, Nathan Cowieson, Javier Perez, Niki Baccile
Langmuir, Jul 2020 DOI: 10.1021/acs.langmuir.0c01177
Journal Paper B21-High Throughput SAXS
Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release
Henry J. Bailey, Gustavo A. Bezerra, Jason R. Marcero, Siladitya Padhi, William R. Foster, Elzbieta Rembeza, Arijit Roy, David F. Bishop, Robert J. Desnick, Gopalakrishnan Bulusu, Harry A. Dailey, Wyatt W. Yue
Nature Communications, 11 June 2020 DOI: 10.1038/s41467-020-16586-x
Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography I24-Microfocus Macromolecular Crystallography open access
The dual PDZ domain from Postsynaptic density protein 95 forms a scaffold with peptide ligand
N. A. Rodzli, M. P. Lockhart-Cairns, C. W. Levy, J. Chipperfield, L. Bird, C. Baldock, S. M. Prince
Biophysical Journal, June 2020 DOI: 10.1016/j.bpj.2020.06.018
Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) I04-Macromolecular Crystallography open access
Ethosomes for coenzyme Q10 cutaneous administration: From design to 3D skin tissue evaluation
Maddalena Sguizzato, Paolo Mariani, Francesco Spinozzi, Mascia Benedusi, Franco Cervellati, Rita Cortesi, Markus Drechsler, Roxane Prieux, Giuseppe Valacchi, Elisabetta Esposito
Antioxidants, 9 June 2020 DOI: 10.3390/antiox9060485
Journal Paper B21-High Throughput SAXS open access
Methionine-rich loop of multicopper oxidase McoA follows open-to-close transitions with a role in enzyme catalysis
Patricia Borges, Vânia Brissos, Guillem Hernandez, Laura Masgrau, Maria Fátima Lucas, Emanuele Monza, Carlos Frazao, Tiago Cordeiro, Lígia O. Martins
Acs Catalysis, June 2020 DOI: 10.1021/acscatal.0c01623
Journal Paper B21-High Throughput SAXS
Structure, dynamics and cellular insight into novel substrates of the Legionella pneumophila type II secretion system
Theo J. Portlock, Jessica Y. Tyson, Sarath C. Dantu, Saima Rehman, Richard C. White, Ian E. Mcintire, Lee Sewell, Katherine Richardson, Rosie Shaw, Alessandro Pandini, Nicholas P. Cianciotto, James Garnett
Frontiers In Molecular Biosciences, 7 June 2020 DOI: 10.3389/fmolb.2020.00112
Journal Paper B21-High Throughput SAXS I04-Macromolecular Crystallography open access
Revealing the complexity of ionic liquid–protein interactions through a multi-technique investigation
Liem Bui-Le, Coby J. Clarke, Andreas Brohl, Alex P. S. Brogan, James A. J. Arpino, Karen M. Polizzi, Jason P. Hallett
Communications Chemistry, 3 May 2020 DOI: 10.1038/s42004-020-0302-5
Journal Paper B21-High Throughput SAXS B23-Circular Dichroism open access
Structural and hydrodynamic characterization of dimeric human oligoadenylate synthetase 2
Amit Koul, Darren Gemmill, Nikhat Lubna, Markus Meier, Natalie Krahn, Evan P. Booy, Jörg Stetefeld, Trushar R. Patel, Sean A. Mckenna
Biophysical Journal, May 2020 DOI: 10.1016/j.bpj.2020.04.025
Journal Paper B21-High Throughput SAXS open access
Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation
Saima Rehman, Lubov S. Grigoryeva, Katherine H. Richardson, Paula Corsini, Richard C. White, Rosie Shaw, Theo J. Portlock, Benjamin Dorgan, Zeinab S. Zanjani, Arianna Fornili, Nicholas P. Cianciotto, James Garnett
Plos Pathogens, 16 May 2020 DOI: 10.1371/journal.ppat.1008342
Journal Paper B21-High Throughput SAXS I02-Macromolecular Crystallography I04-Macromolecular Crystallography open access
Purification and structural characterization of aggregation-prone human TDP-43 involved in neurodegenerative diseases
Gareth S. A. Wright, Tatiana F. Watanabe, Kangsa Amporndanai, Steven S. Plotkin, Neil R. Cashman, Svetlana V. Antonyuk, S. Samar Hasnain
Iscience, May 2020 DOI: 10.1016/j.isci.2020.101159
Journal Paper B21-High Throughput SAXS I03-Macromolecular Crystallography open access
Chain-end modifications and sequence arrangements of antimicrobial peptoids for mediating activity and nano-assembly
Abshar Hasan, Varun Saxena, Valeria Castelletto, Georgina Zimbitas, Jani Seitsonen, Janne Ruokolainen, Lalit M. Pandey, Jan Sefcik, Ian W. Hamley, King Hang Aaron Lau
Frontiers In Chemistry, 8 May 2020 DOI: 10.3389/fchem.2020.00416
Journal Paper B21-High Throughput SAXS open access
Isotype switching converts anti-CD40 antagonism to agonism to elicit potent antitumor activity
Xiaojie Yu, H.t. Claude Chan, Hayden Fisher, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Vikki English, J. Sjef Verbeek, Ann L. White, Ivo Tews, Martin J. Glennie, Mark S. Cragg
Cancer Cell, May 2020 DOI: 10.1016/j.ccell.2020.04.013
Journal Paper B21-High Throughput SAXS open access
Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2
Leanne Milton-Harris, Mark Jeeves, Sarah A. Walker, Simon E. Ward, Erika J. Mancini
Oncotarget, 11 May 2020 DOI: 10.18632/oncotarget.27580
Journal Paper B21-High Throughput SAXS open access
Nanoparticulate gels for cutaneous administration of caffeic acid
Maddalena Sguizzato, Paolo Mariani, Francesca Ferrara, Markus Drechsler, Supandeep Singh Hallan, Nicolas Huang, Fanny Simelière, Nikul Khunti, Rita Cortesi, Nicola Marchetti, Giuseppe Valacchi, Elisabetta Esposito
Nanomaterials, 10 May 2020 DOI: 10.3390/nano10050961
Journal Paper B21-High Throughput SAXS open access
Diamond’s 9000th publication: green materials for thermal energy storage
Diamond Light Source
May 2020
Science Highlight B21-High Throughput SAXS
Magnetic field-induced alignment of nanofibrous supramolecular membranes: a molecular design approach to create tissue-like biomaterials
Elham Radvar, Yejiao Shi, Salvatore Grasso, Charlotte J. C. Edwards-Gayle, Xitong Liu, Meagan S. Mauter, Valeria Castelletto, Ian W. Hamley, Michael J. Reece, Helena S. Azevedo
Acs Applied Materials & Interfaces, Apr 2020 DOI: 10.1021/acsami.0c05191
Journal Paper B21-High Throughput SAXS
Pyocin s5 import into Pseudomonas aeruginosa reveals a generic mode of bacteriocin transport
Hannah M. Behrens, Edward D. Lowe, Joseph Gault, Nicholas G. Housden, Renata Kaminska, T. Moritz Weber, Catriona M. A. Thompson, Gaëtan L. A. Mislin, Isabelle J. Schalk, Daniel Walker, Carol V. Robinson, Colin Kleanthous
Mbio, 11 Apr 2020 DOI: 10.1128/mBio.03230-19
Journal Paper B21-High Throughput SAXS open access
Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-β-synthase domain
Akira Imamura, Tetsuya Okada, Hikaru Mase, Takuya Otani, Tomoka Kobayashi, Manatsu Tamura, Bruno Kilunga Kubata, Katsuaki Inoue, Robert P. Rambo, Susumu Uchiyama, Kentaro Ishii, Shigenori Nishimura, Takashi Inui
Nature Communications, 11 Apr 2020 DOI: 10.1038/s41467-020-15611-3
Journal Paper B21-High Throughput SAXS open access
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells
Jingjing Zhang, Manickam Gurusaran, Yasuhiro Fujiwara, Kexin Zhang, Meriem Echbarthi, Egor Vorontsov, Rui Guo, Devon F. Pendlebury, Intekhab Alam, Gabriel Livera, Martini Emmanuelle, P. Jeremy Wang, Jayakrishnan Nandakumar, Owen Davies, Hiroki Shibuya
Nature Communications, 11 Apr 2020 DOI: 10.1038/s41467-020-15954-x
Journal Paper B21-High Throughput SAXS open access
Colloidal features of softwood galactoglucomannans-rich extract
Mamata Bhattarai, Irina Sulaeva, Leena Pitkänen, Inkeri Kontro, Maija Tenkanen, Antje Potthast, Kirsi S. Mikkonen
Carbohydrate Polymers, Apr 2020 DOI: 10.1016/j.carbpol.2020.116368
Journal Paper B21-High Throughput SAXS open access
Self-assembled gold nanoparticles and amphiphile peptides: a colorimetric probe for copper( ii ) ion detection
Juliane N. B. D. Pelin, Charlotte J. C. Edwards-Gayle, Herculano Martinho, Barbara B. Gerbelli, Valeria Castelletto, Ian W. Hamley, Wendel A. Alves
Dalton Transactions, 53 Apr 2020 DOI: 10.1039/D0DT00844C
Journal Paper B21-High Throughput SAXS
Modulating the release of pharmaceuticals from lipid cubic phases using a lipase inhibitor
Michele Dully, Christopher Brasnett, Ahmed Djeghader, Annela Seddon, John Neilan, David Murray, James Butler, Tewfik Soulimane, Sarah P. Hudson
Journal Of Colloid And Interface Science, Apr 2020 DOI: 10.1016/j.jcis.2020.04.015
Journal Paper B21-High Throughput SAXS open access
Polymorphism of asymmetric catalysts based on amphiphilic lipopeptides in solution
Juliane N. B. D. Pelin, Charlotte J. C. Edwards-Gayle, Andrea Aguilar, Amanpreet Kaur, Ian W. Hamley, Wendel A. Alves
Soft Matter, Apr 2020 DOI: 10.1039/D0SM00245C
Journal Paper B21-High Throughput SAXS
Molecular flexibility of DNA as a key determinant of RAD 51 recruitment
Federico Paoletti, Afaf H. El-Sagheer, Jun Allard, Tom Brown, Omer Dushek, Fumiko Esashi
The Embo Journal, 39 Apr 2020 DOI: 10.15252/embj.2019103002
Journal Paper B21-High Throughput SAXS open access
Lignin-fatty acid hybrid nanocapsules for scalable thermal energy storage in phase-change materials
Mika H. Sipponen, Alexander Henn, Paavo Penttilä, Monika Österberg
Chemical Engineering Journal, Mar 2020 DOI: 10.1016/j.cej.2020.124711
Journal Paper B21-High Throughput SAXS open access
Self-assembly, nematic phase formation, and organocatalytic behavior of a proline-functionalized lipopeptide
Juliane N. B. D. Pelin, Charlotte J. C. Edwards-Gayle, Valeria Castelletto, Andrea M. Aguilar, Wendel A. Alves, Jani Seitsonen, Janne Ruokolainen, Ian W. Hamley
Acs Applied Materials & Interfaces, Mar 2020 DOI: 10.1021/acsami.0c00686
Journal Paper B21-High Throughput SAXS open access
A single-component photorheological fluid with light-responsive viscosity
Elaine A. Kelly, Niamh Willis-Fox, Judith E. Houston, Camille Blayo, Giorgio Divitini, Nathan Cowieson, Ronan Daly, Rachel C. Evans
Nanoscale, 12 Mar 2020 DOI: 10.1039/C9NR10350C
Journal Paper B21-High Throughput SAXS open access
Amyloid peptide mixtures: self-assembly, hydrogelation, nematic ordering, and catalysts in aldol reactions
Juliane N. B. D. Pelin, Barbara B. Gerbelli, Charlotte J. C. Edwards-Gayle, Andrea M. Aguilar, Valeria Castelletto, Ian W. Hamley, Wendel A. Alves
Langmuir, Mar 2020 DOI: 10.1021/acs.langmuir.0c00198
Journal Paper B21-High Throughput SAXS open access
Controlling the properties of the micellar and gel phase by varying the counterion in functionalised-dipeptide systems
Kate Mcaulay, Pedro Agís Ucha, Han Wang, Ana M. Fuentes-Caparros, Lisa Thomson, Osama Maklad, Nikul Khunti, Nathan Cowieson, Matthew Wallace, Honggang Cui, Robert J. Poole, Annela Seddon, Dave J. Adams
Chemical Communications, 97 Mar 2020 DOI: 10.1039/D0CC01252A
Journal Paper B21-High Throughput SAXS open access
Functional homo- and heterodimeric actin capping proteins from the malaria parasite
Abris Adam Bendes, Moon Chatterjee, Benjamin Götte, Petri Kursula, Inari Kursula
Biochemical And Biophysical Research Communications, Mar 2020 DOI: 10.1016/j.bbrc.2020.02.119
Journal Paper B21-High Throughput SAXS
The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture
Catherine R. Back, Victoria A. Higman, Kristian Levay, Viren V. Patel, Alice E. Parnell, Daniel Frankel, Howard F. Jenkinson, Steven G. Burston, Matthew P. Crump, Angela H. Nobbs, Paul R. Race
Journal Of Biological Chemistry, Mar 2020 DOI: 10.1074/jbc.RA119.011719
Journal Paper B21-High Throughput SAXS open access
Ellagic acid containing nanostructured lipid carriers for topical application: a preliminary study
Supandeep Singh Hallan, Maddalena Sguizzato, Gabriella Pavoni, Anna Baldisserotto, Markus Drechsler, Paolo Mariani, Elisabetta Esposito, Rita Cortesi
Molecules, 25 Mar 2020 DOI: 10.3390/molecules25061449
Journal Paper B21-High Throughput SAXS open access
Membrane stability in the presence of methacrylate esters
Vivien Yeh, Alice Goode, Graham Eastham, Robert P. Rambo, Katsuaki Inoue, James Doutch, Boyan B. Bonev
Langmuir, Mar 2020 DOI: 10.1021/acs.langmuir.9b03759
Journal Paper B21-High Throughput SAXS open access
Conformation and phase behavior of sodium carboxymethyl cellulose in the presence of mono- and divalent salts
William N. Sharratt, Róisín O’connell, Sarah E. Rogers, Carlos G. Lopez, Joao T. Cabral
Macromolecules, Feb 2020 DOI: 10.1021/acs.macromol.9b02228
Journal Paper B21-High Throughput SAXS
Phosphorylation of a disordered peptide – structural effects and force field inconsistencies
Ellen Rieloff, Marie Skepö
Journal Of Chemical Theory And Computation, Feb 2020 DOI: 10.1021/acs.jctc.9b01190
Journal Paper B21-High Throughput SAXS open access
Mechanism of crosstalk between the LSD1 demethylase and HDAC1 deacetylase in the CoREST complex
Yun Song, Lisbeth Dagil, Louise Fairall, Naomi Robertson, Mingxuan Wu, T. J. Ragan, Christos G. Savva, Almutasem Saleh, Nobuhiro Morone, Micha B. A. Kunze, Andrew G. Jamieson, Philip A. Cole, D. Flemming Hansen, John W. R. Schwabe
Cell Reports, 30 Feb 2020 DOI: 10.1016/j.celrep.2020.01.091
Journal Paper B21-High Throughput SAXS Krios I-Titan Krios I at Diamond open access
Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein
Lenka Stejskal, William D. Lees, David S. Moss, Machaela Palor, Richard J. Bingham, Adrian J. Shepherd, Joe Grove
Plos Computational Biology, 16 Feb 2020 DOI: 10.1371/journal.pcbi.1007710
Journal Paper B21-High Throughput SAXS open access
Solution structure of the cytoplasmic domain of NhaP2 a K+/H+ antiporter from Vibrio cholera
George L. Orriss, Vu To, Aniel Moya-Torres, Genevieve Seabrook, Joe O'Neil, Jörg Stetefeld
Biochimica Et Biophysica Acta (bba) - Biomembranes, Feb 2020 DOI: 10.1016/j.bbamem.2020.183225
Journal Paper B21-High Throughput SAXS
Investigating the influence of solvent quality on RAFT-mediated PISA of sulfonate-functional diblock copolymer nanoparticles
Shang-Pin Wen, Jack G. Saunders, Lee A. Fielding
Polymer Chemistry, 268 Feb 2020 DOI: 10.1039/C9PY01912J
Journal Paper B21-High Throughput SAXS
Oligomerization and characteristics of phosphoenolpyruvate carboxylase in Synechococcus PCC 7002
Claudia Durall De La Fuente, Sandesh Kanchugal Puttaswamy, Maria Selmer, Peter Lindblad
Scientific Reports, 10 Feb 2020 DOI: 10.1038/s41598-020-60249-2
Journal Paper B21-High Throughput SAXS open access
Nanoscale structure determination of Murray Valley encephalitis and Powassan virus non-coding RNAs
Tyler Mrozowich, Amy Henrickson, Borries Demeler, Trushar Patel
Viruses, 12 Jan 2020 DOI: 10.3390/v12020190
Journal Paper B21-High Throughput SAXS open access
Multimeric antibodies with increased valency surpassing functional affinity and potency thresholds using novel formats
Ami Miller, Stephen Carr, Terry Rabbitts, Hanif Ali
Mabs, 12 Jan 2020 DOI: 10.1080/19420862.2020.1752529
Journal Paper B21-High Throughput SAXS open access
Solution structure and oligomeric state of the E. coli glycerol facilitator
Mary Hernando, George Orris, Jacqueline Perodeau, Shixing Lei, Fraser G. Ferens, Trushar R. Patel, Jörg Stetefeld, Andrew J. Nieuwkoop, Joe D. O'Neil
Biochimica Et Biophysica Acta (bba) - Biomembranes, Jan 2020 DOI: 10.1016/j.bbamem.2020.183191
Journal Paper B21-High Throughput SAXS
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
Doo Nam Kim, Bernhard C. Thiel, Tyler Mrozowich, Scott P. Hennelly, Ivo L. Hofacker, Trushar R. Patel, Karissa Y. Sanbonmatsu
Nature Communications, 11 Jan 2020 DOI: 10.1038/s41467-019-13942-4
Journal Paper B21-High Throughput SAXS open access
Selective antibacterial activity and lipid membrane interactions of arginine-rich amphiphilic peptides
Charlotte J. C. Edwards-Gayle, Glyn Barrett, Shyamali Roy, Valeria Castelletto, Jani Seitsonen, Janne Ruokolainen, Ian W. Hamley
Acs Applied Bio Materials, Jan 2020 DOI: 10.1021/acsabm.9b00894
Journal Paper B21-High Throughput SAXS open access
Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate
Stephen Mcmahon, Wenlong Zhu, Shirley Graham, Robert Rambo, Malcolm F. White, Tracey M. Gloster
Nature Communications, 11 Jan 2020 DOI: 10.1038/s41467-019-14222-x
Journal Paper B21-High Throughput SAXS I04-1-Macromolecular Crystallography (fixed wavelength) open access
Supertertiary structure analysis and comparison of BET proteins upon bivalent binding
Ailefeila Aihemaiti
Jan 2020
Thesis B21-High Throughput SAXS
  1. Eric Fagerberg, Linda K. Månsson, Samuel Lenton, Marie Skepö, "The effects of chain length on the structural properties of intrinsically disordered proteins in concentrated solutions", The Journal Of Physical Chemistry B, 124, 11843 - 11853 (2020), DOI: 10.1021/acs.jpcb.0c09635
  2. Ankoor Patel, Emmely E. Treffers, Markus Meier, Trushar R. Patel, Jörg Stetefeld, Eric J. Snijder, Brian L. Mark, "Molecular characterization of the RNA-protein complex directing -2/-1 programmed ribosomal frameshifting during arterivirus replicase expression", Journal Of Biological Chemistry, 295, 17904-17921 (2020), DOI: 10.1074/jbc.RA120.016105
  3. Abril Gijsbers, Nuria Sánchez-Puig, Ye Gao, Peter J. Peters, Raimond B. G. Ravelli, Dritan Siliqi, "Structural analysis of the partially disordered protein EspK from Mycobacterium tuberculosis", Crystals, 11 (2020), DOI: 10.3390/cryst11010018
  4. Charlotte Jennifer Chante Edwards-Gayle, Nikul Khunti, Ian W. Hamley, Katsuaki Inoue, Nathan Cowieson, Robert Rambo, "Design of a multipurpose sample cell holder for the Diamond Light Source high-throughput SAXS beamline B21", Journal Of Synchrotron Radiation, 28 (2020), DOI: 10.1107/S1600577520013831
  5. Annika Soderholm, Matilda S. Newton, Wayne M. Patrick, Maria Selmer, "Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa - decarboxylation is not essential for indole formation", Journal Of Biological Chemistry, 295(47), 15948-15956 (2020), DOI: 10.1074/jbc.RA120.014936
  6. James G. Hyatt, Sylvain Prévost, Juliette M. Devos, Courtney J. Mycroft-West, Mark A. Skidmore, Anja Winter, "Molecular changes in dengue envelope protein domain III upon interaction with glycosaminoglycans", Pathogens, 9 (2020), DOI: 10.3390/pathogens9110935
  7. Supandeep Singh Hallan, Paolo Marchetti, Daria Bortolotti, Maddalena Sguizzato, Elisabetta Esposito, Paolo Mariani, Claudio Trapella, Roberta Rizzo, Rita Cortesi, "Design of nanosystems for the delivery of quorum sensing inhibitors: A preliminary study", Molecules, 25 (2020), DOI: 10.3390/molecules25235655
  8. Maria S. Eriksen, Oleksii Nikolaienko, Erik I. Hallin, Sverre Grødem, Helene J. Bustad, Marte I. Flydal, Ian Merski, Tomohisa Hosokawa, Daniela Lascu, Shreeram Akerkar, Jorge Cuellar, James J. Chambers, Rory O’connell, Gopinath Muruganandam, Remy Loris, Christine Touma, Tambudzai Kanhema, Yasunori Hayashi, Margaret M. Stratton, José M. Valpuesta, Petri Kursula, Aurora Martinez, Clive R. Bramham, "Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif", The Febs Journal, 3 (2020), DOI: 10.1111/febs.15618
  9. Kristian Le Vay, Ben M. Carter, Daniel W. Watkins, T.-Y. Dora Tang, Valeska P. Ting, Helmut Cölfen, Robert P. Rambo, Andrew J. Smith, J. L. Ross Anderson, Adam W. Perriman, "Controlling protein nanocage assembly with hydrostatic pressure", Journal Of The American Chemical Society (2020), DOI: 10.1021/jacs.0c07285
  10. Camille Blayo, Elaine A. Kelly, Judith E. Houston, Nikul Khunti, Nathan P. Cowieson, Rachel C. Evans, "Light-responsive self-assembly of a cationic azobenzene surfactant at high concentration", Soft Matter, 56 (2020), DOI: 10.1039/D0SM01512A
  11. Waraporn Bunnak, Ashley J. Winter, Colin M. Lazarus, Matthew P. Crump, Paul R. Race, Pakorn Wattana‐amorn, "SAXS reveals highly flexible interdomain linkers of tandem acyl carrier protein–thioesterase domains from a fungal non‐reducing polyketide synthase", Febs Letters (2020), DOI: 10.1002/1873-3468.13954
  12. [Thesis] Stephen Moss, "Structure-function studies of key amyloid-degrading enzymes" (2020)
  13. Daniel Mcdowall, Benjamin J. Greeves, Rob Clowes, Kate Mcaulay, Ana M. Fuentes‐caparrós, Lisa Thomson, Nikul Khunti, Nathan Cowieson, Michael C. Nolan, Matthew Wallace, Andrew I. Cooper, Emily R. Draper, Alexander J. Cowan, Dave J. Adams, "Controlling photocatalytic activity by self‐assembly – tuning perylene bisimide photocatalysts for the hydrogen evolution reaction", Advanced Energy Materials, 10 (2020), DOI: 10.1002/aenm.202002469
  14. Talia A. Shmool, Laura K. Martin, Coby J. Clarke, Liem Bui-Le, Karen M. Polizzi, Jason P. Hallett, "Exploring conformational preferences of proteins: ionic liquid effects on the energy landscape of avidin", Chemical Science, 5 (2020), DOI: 10.1039/D0SC04991C
  15. Liem Bui-Le, Alex P. S. Brogan, Jason P. Hallett, "Solvent‐free liquid avidin as a step towards cold chain elimination", Biotechnology And Bioengineering (2020), DOI: 10.1002/bit.27587
  16. Biplab Mondal, Dipayan Bairagi, Nibedita Nandi, Biswanath Hansda, Krishna Sundar Das, Charlotte J. C. Edwards-Gayle, Valeria Castelletto, Ian W. Hamley, Arindam Banerjee, "Peptide-based gel in environmental remediation: removal of toxic organic dyes and hazardous Pb2+ and Cd2+ ions from wastewater and oil spill recovery", Langmuir (2020), DOI: 10.1021/acs.langmuir.0c02205
  17. Chatrin Chatrin, Mads Gabrielsen, Lori Buetow, Mark A. Nakasone, Syed F. Ahmed, David Sumpton, Gary J. Sibbet, Brian O. Smith, Danny Huang, "Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases", Science Advances, 6 (2020), DOI: 10.1126/sciadv.abc0418
  18. Valeria Castelletto, Jani Seitsonen, Janne Ruokolainen, Cristian Piras, Rainer Cramer, Charlotte J. C. Edwards-Gayle, Ian W. Hamley, "Peptide nanotubes self-assembled from leucine-rich alpha helical surfactant-like peptides", Chemical Communications, 369 (2020), DOI: 10.1039/D0CC04299D
  19. Rasmus Ree, Laura Kind, Anna Kaziales, Sylvia Varland, Minglu Dai, Klaus Richter, Adrian Drazic, Thomas Arnesen, "PFN2 and NAA80 cooperate to efficiently acetylate the N-terminus of actin", Journal Of Biological Chemistry (2020), DOI: 10.1074/jbc.RA120.015468
  20. Fernando Sánchez-Sáez, Laura Gómez-H, Orla M. Dunne, Cristina Gallego-Páramo, Natalia Felipe-Medina, Manuel Sánchez-Martín, Elena Llano, Alberto M. Pendas, Owen R. Davies, "Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility", Science Advances, 6 (2020), DOI: 10.1126/sciadv.abb1660
  21. Annalaura Sabatucci, Francesca Pintus, Tiziana Cabras, Federica Vincenzoni, Mauro Maccarrone, Rosaria Medda, Enrico Dainese, "Structure of a nucleotide pyrophosphatase/phosphodiesterase (NPP) from Euphorbia characias latex characterized by small-angle X-ray scattering: clues for the general organization of plant NPPs", Acta Crystallographica Section D Structural Biology, 76, 857 - 867 (2020), DOI: 10.1107/S2059798320010207
  22. Alice J. Bochel, Christopher Williams, Airlie J. Mccoy, Hans-Jürgen Hoppe, Ashley J. Winter, Ryan D. Nicholls, Karl Harlos, E. Yvonne Jones, Imre Berger, A. Bassim Hassan, Matthew P. Crump, "Structure of the human cation-independent mannose 6-phosphate/IGF2 receptor domains 7–11 uncovers the mannose 6-phosphate binding site of domain 9", Structure (2020), DOI: 10.1016/j.str.2020.08.002
  23. Nathan P. Cowieson, Charlotte J. C. Edwards-Gayle, Katsuaki Inoue, Nikul S. Khunti, James Doutch, Eugene Williams, Steven Daniels, Geoff Preece, Nicholas A. Krumpa, John P. Sutter, Mark D. Tully, Nick J. Terrill, Robert P. Rambo, "Beamline B21: high-throughput small-angle X-ray scattering at Diamond Light Source", Journal Of Synchrotron Radiation, 27 (2020), DOI: 10.1107/S1600577520009960
  24. Michael P. Lockhart-Cairns, Helena Newandee, Jennifer Thomson, Anthony S. Weiss, Clair Baldock, Anna Tarakanova, "Transglutaminase-mediated cross-linking of tropoelastin to fibrillin stabilises the elastin precursor prior to elastic fibre assembly", Journal Of Molecular Biology (2020), DOI: 10.1016/j.jmb.2020.08.023
  25. Salla I. Virtanen, Anne M. Kiirikki, Kornelia M. Mikula, Hideo Iwaï, O. H. Samuli Ollila, "Heterogeneous dynamics in partially disordered proteins", Physical Chemistry Chemical Physics, 337 (2020), DOI: 10.1039/D0CP03473H
  26. Merav Segal, Lihi Ozery, Gadi Slor, Shreyas Shankar Wagle, Tamara Ehm, Roy Beck, Roey J. Amir, "The architectural change of the shell forming block from linear to V-shaped accelerates micellar disassembly but slows the complete enzymatic degradation of the amphiphiles", Biomacromolecules (2020), DOI: 10.1021/acs.biomac.0c00882
  27. Supandeep Singh Hallan, Maddalena Sguizzato, Paolo Mariani, Rita Cortesi, Nicolas Huang, Fanny Simelière, Nicola Marchetti, Markus Drechsler, Tautgirdas Ruzgas, Elisabetta Esposito, "Design and characterization of ethosomes for transdermal delivery of caffeic acid", Pharmaceutics, 12 (2020), DOI: 10.3390/pharmaceutics12080740
  28. Igor Tascon, Xiao Li, María Lucas, D’anna Nelson, Ander Vidaurrazaga, Yi-Han Lin, Adriana L. Rojas, Aitor Hierro, Matthias P. Machner, "Structural insight into the membrane targeting domain of the Legionella deAMPylase SidD", Plos Pathogens, 16 (2020), DOI: 10.1371/journal.ppat.1008734
  29. Gustavo A. Bezerra, William R. Foster, Henry J. Bailey, Kevin G. Hicks, Sven W. Sauer, Bianca Dimitrov, Thomas J. Mccorvie, Jürgen G. Okun, Jared Rutter, Stefan Kölker, Wyatt W. Yue, "Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism", Iucrj, 7 (2020), DOI: 10.1107/S205225252000696X
  30. Kate Mcauley, Han Wang, Ana M. Fuentes-Caparros, Lisa Thomson, Nikul Khunti, Nathan P. Cowieson, Honggang Cui, Annela Seddon, Dave J. Adams, "Isotopic control over self-assembly in supramolecular gels", Langmuir (2020), DOI: 10.1021/acs.langmuir.0c01552
  31. C. Seyrig, P. Le Griel, N. Cowieson, J. Perez, N. Baccile, "Synthesis of multilamellar walls vesicles polyelectrolyte surfactant complexes from pH-stimulated phase transition using microbial biosurfactants", Journal Of Colloid And Interface Science (2020), DOI: 10.1016/j.jcis.2020.07.021
  32. Luca Martinelli, Athanasios Adamopoulos, Patrik Johansson, Paul T. Wan, Jenny Gunnarsson, Hongwei Guo, Helen Boyd, Noam Zelcer, Titia K. Sixma, "Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate binding site", Journal Of Biological Chemistry (2020), DOI: 10.1074/jbc.RA120.014349
  33. Giuditta Dal Cortivo, Valerio Marino, Francesco Boni, Mario Milani, Daniele Dell'Orco, "Missense mutations affecting Ca2+-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties", Biochimica Et Biophysica Acta (bba) - Molecular Cell Research (2020), DOI: 10.1016/j.bbamcr.2020.118794
  34. Sudeep Karki, Alexander V. Shkumatov, Sungwon Bae, Hyeonho Kim, Jaewon Ko, Tommi Kajander, "Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ", Scientific Reports, 10 (2020), DOI: 10.1038/s41598-020-68502-4
  35. Ondřej Skořepa, Samuel Pazicky, Barbora Kalousková, Jan Bláha, Celeste Abreu, Tomáš Ječmen, Michal Rosůlek, Alexander Fish, Arthur Sedivy, Karl Harlos, Jan Dohnalek, Tereza Skálová, Ondřej Vaněk, "Natural killer cell activation receptor NKP30 oligomerization depends on its n-glycosylation", Cancers, 12 (2020), DOI: 10.3390/cancers12071998
  36. Harshul Arora Verasztó, Maria Logotheti, Reinhard Albrecht, Alexander Leitner, Hongbo Zhu, Marcus D. Hartmann, "Architecture and functional dynamics of the pentafunctional AROM complex", Nature Chemical Biology, 64 (2020), DOI: 10.1038/s41589-020-0587-9
  37. Ane Rodrigo-Unzueta, Mattia Ghirardello, Saioa Urresti, Ignacio Delso, David Giganti, Itxaso Anso, Beatriz Trastoy, Natalia Comino, Montse Tersa, Cecilia D'Angelo, Javier O. Cifuente, Alberto Marina, Jobst Liebau, Lena Mäler, Alexandre Chenal, David Albesa-Jove, Pedro Merino, Marcelo E. Guerin, "Dissecting the structural and chemical determinants of the 'open-to-closed' motion in the mannosyltransferase PimA from mycobacteria", Biochemistry (2020), DOI: 10.1021/acs.biochem.0c00376
  38. Chloe Seyrig, Gertrude Kignelman, Wim Thielemans, Patrick Le Griel, Nathan Cowieson, Javier Perez, Niki Baccile, "Stimuli-induced nonequilibrium phase transitions in polyelectrolyte–surfactant complex coacervates", Langmuir (2020), DOI: 10.1021/acs.langmuir.0c01177
  39. Henry J. Bailey, Gustavo A. Bezerra, Jason R. Marcero, Siladitya Padhi, William R. Foster, Elzbieta Rembeza, Arijit Roy, David F. Bishop, Robert J. Desnick, Gopalakrishnan Bulusu, Harry A. Dailey, Wyatt W. Yue, "Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release", Nature Communications, 11 (2020), DOI: 10.1038/s41467-020-16586-x
  40. N. A. Rodzli, M. P. Lockhart-Cairns, C. W. Levy, J. Chipperfield, L. Bird, C. Baldock, S. M. Prince, "The dual PDZ domain from Postsynaptic density protein 95 forms a scaffold with peptide ligand", Biophysical Journal (2020), DOI: 10.1016/j.bpj.2020.06.018
  41. Maddalena Sguizzato, Paolo Mariani, Francesco Spinozzi, Mascia Benedusi, Franco Cervellati, Rita Cortesi, Markus Drechsler, Roxane Prieux, Giuseppe Valacchi, Elisabetta Esposito, "Ethosomes for coenzyme Q10 cutaneous administration: From design to 3D skin tissue evaluation", Antioxidants, 9 (2020), DOI: 10.3390/antiox9060485
  42. Patricia Borges, Vânia Brissos, Guillem Hernandez, Laura Masgrau, Maria Fátima Lucas, Emanuele Monza, Carlos Frazao, Tiago Cordeiro, Lígia O. Martins, "Methionine-rich loop of multicopper oxidase McoA follows open-to-close transitions with a role in enzyme catalysis", Acs Catalysis (2020), DOI: 10.1021/acscatal.0c01623
  43. Theo J. Portlock, Jessica Y. Tyson, Sarath C. Dantu, Saima Rehman, Richard C. White, Ian E. Mcintire, Lee Sewell, Katherine Richardson, Rosie Shaw, Alessandro Pandini, Nicholas P. Cianciotto, James Garnett, "Structure, dynamics and cellular insight into novel substrates of the Legionella pneumophila type II secretion system", Frontiers In Molecular Biosciences, 7 (2020), DOI: 10.3389/fmolb.2020.00112
  44. Liem Bui-Le, Coby J. Clarke, Andreas Brohl, Alex P. S. Brogan, James A. J. Arpino, Karen M. Polizzi, Jason P. Hallett, "Revealing the complexity of ionic liquid–protein interactions through a multi-technique investigation", Communications Chemistry, 3 (2020), DOI: 10.1038/s42004-020-0302-5
  45. Amit Koul, Darren Gemmill, Nikhat Lubna, Markus Meier, Natalie Krahn, Evan P. Booy, Jörg Stetefeld, Trushar R. Patel, Sean A. Mckenna, "Structural and hydrodynamic characterization of dimeric human oligoadenylate synthetase 2", Biophysical Journal (2020), DOI: 10.1016/j.bpj.2020.04.025
  46. Saima Rehman, Lubov S. Grigoryeva, Katherine H. Richardson, Paula Corsini, Richard C. White, Rosie Shaw, Theo J. Portlock, Benjamin Dorgan, Zeinab S. Zanjani, Arianna Fornili, Nicholas P. Cianciotto, James Garnett, "Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation", Plos Pathogens, 16 (2020), DOI: 10.1371/journal.ppat.1008342
  47. Gareth S. A. Wright, Tatiana F. Watanabe, Kangsa Amporndanai, Steven S. Plotkin, Neil R. Cashman, Svetlana V. Antonyuk, S. Samar Hasnain, "Purification and structural characterization of aggregation-prone human TDP-43 involved in neurodegenerative diseases", Iscience (2020), DOI: 10.1016/j.isci.2020.101159
  48. Abshar Hasan, Varun Saxena, Valeria Castelletto, Georgina Zimbitas, Jani Seitsonen, Janne Ruokolainen, Lalit M. Pandey, Jan Sefcik, Ian W. Hamley, King Hang Aaron Lau, "Chain-end modifications and sequence arrangements of antimicrobial peptoids for mediating activity and nano-assembly", Frontiers In Chemistry, 8 (2020), DOI: 10.3389/fchem.2020.00416
  49. Xiaojie Yu, H.t. Claude Chan, Hayden Fisher, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Vikki English, J. Sjef Verbeek, Ann L. White, Ivo Tews, Martin J. Glennie, Mark S. Cragg, "Isotype switching converts anti-CD40 antagonism to agonism to elicit potent antitumor activity", Cancer Cell (2020), DOI: 10.1016/j.ccell.2020.04.013
  50. Leanne Milton-Harris, Mark Jeeves, Sarah A. Walker, Simon E. Ward, Erika J. Mancini, "Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2", Oncotarget, 11, 1737 - 1748 (2020), DOI: 10.18632/oncotarget.27580
  51. Maddalena Sguizzato, Paolo Mariani, Francesca Ferrara, Markus Drechsler, Supandeep Singh Hallan, Nicolas Huang, Fanny Simelière, Nikul Khunti, Rita Cortesi, Nicola Marchetti, Giuseppe Valacchi, Elisabetta Esposito, "Nanoparticulate gels for cutaneous administration of caffeic acid", Nanomaterials, 10 (2020), DOI: 10.3390/nano10050961
  52. [Science Highlight] Diamond Light Source, "Diamond’s 9000th publication: green materials for thermal energy storage" (2020)
  53. Elham Radvar, Yejiao Shi, Salvatore Grasso, Charlotte J. C. Edwards-Gayle, Xitong Liu, Meagan S. Mauter, Valeria Castelletto, Ian W. Hamley, Michael J. Reece, Helena S. Azevedo, "Magnetic field-induced alignment of nanofibrous supramolecular membranes: a molecular design approach to create tissue-like biomaterials", Acs Applied Materials & Interfaces (2020), DOI: 10.1021/acsami.0c05191
  54. Hannah M. Behrens, Edward D. Lowe, Joseph Gault, Nicholas G. Housden, Renata Kaminska, T. Moritz Weber, Catriona M. A. Thompson, Gaëtan L. A. Mislin, Isabelle J. Schalk, Daniel Walker, Carol V. Robinson, Colin Kleanthous, "Pyocin s5 import into Pseudomonas aeruginosa reveals a generic mode of bacteriocin transport", Mbio, 11 (2020), DOI: 10.1128/mBio.03230-19
  55. Akira Imamura, Tetsuya Okada, Hikaru Mase, Takuya Otani, Tomoka Kobayashi, Manatsu Tamura, Bruno Kilunga Kubata, Katsuaki Inoue, Robert P. Rambo, Susumu Uchiyama, Kentaro Ishii, Shigenori Nishimura, Takashi Inui, "Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-β-synthase domain", Nature Communications, 11 (2020), DOI: 10.1038/s41467-020-15611-3
  56. Jingjing Zhang, Manickam Gurusaran, Yasuhiro Fujiwara, Kexin Zhang, Meriem Echbarthi, Egor Vorontsov, Rui Guo, Devon F. Pendlebury, Intekhab Alam, Gabriel Livera, Martini Emmanuelle, P. Jeremy Wang, Jayakrishnan Nandakumar, Owen Davies, Hiroki Shibuya, "The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells", Nature Communications, 11 (2020), DOI: 10.1038/s41467-020-15954-x
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Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.

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