eBIC
.JPG)
Eilis is a PDRA and joined the electron Bio-Imaging Centre (eBIC) in August 2022.
Email: eilis.bragginton@diamond.ac.ukEilis Bragginton
Éilís obtained her PhD from the University of Bristol (2019) within the laboratory of Prof. Jim Spencer where she used x-ray crystallography to study the structure and mechanism of antibiotic degrading enzymes.
In 2020, she moved to the University of Birmingham as a research fellow to work in the laboratory of Prof. Stephen Smerdon. Whilst at Birmingham, Éilís used cryo-Electron Microscopy (cryo-EM), x-ray crystallography and biophysical techniques to characterise the structure and function of chromatin binding proteins and signalling modifications to proteins involved in the repair of damaged DNA.
Éilís joined eBIC in August 2022 as a Post-Doctoral Research Associate using cryo-EM to investigate the structure of bacteriophage-like particles. Her research interests include using cryo-EM and cryo-Electron tomography to study the mechanisms bacteria employ for infection, therapeutic evasion, and manipulation of host cells.
Samphire, J. Takebayashi, Y. Hill, S.A. Hill, N. Heesom, K.J. Lewis, P.A. Alibhai, D. Bragginton, E.C. Dorh, J. Dorh, N. Spencer, J. Carmen Galan, M. (2021) Green Fluorescent Carbon Dots as Targeting Probes for LED-Dependent Bacterial Killing. Nano Select, (2021). DOI: 10.1002/nano.202100183.
Azmi, L. Bragginton, E.C. Cadby, I. T. Byron, O. Roe, A. J. Lovering, A. L. Gabrielsen, M. (2020) High-resolution structure of the alcohol dehydrogenase domain of the bifunctional bacterial enzyme AdhE. Acta Crystallogr F Struct Biol Commun, 76(9):414-421. DOI: 10.1107/S2053230X20010237.
Tooke, C.L. Hinchliffe, P. Bragginton, E.C. Colenso, C. K. Hirvonen, V. H. Takebayashi, Y. Spencer, J. (2019) β- Lactamases and β-Lactamase inhibitors in the 21st Century. Journal of Molecular Biology, 431(18):3472-3500. DOI: 10.1016/j.jmb.2019.04.002.
Hall, S.C.L. Tognoloni, C. Charlton, J. Bragginton, É.C. Rothnie, A.J. Sridhar, P. Wheatley, M. Knowles, T. J. Edler, K. J. Arnold, T & Dafforn, T. R. (2018) An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles. Nanoscale, 10(22):10609-10619. DOI: 10.1039/C8NR01322E.
Bragginton, E.C. & Piddock, L.J. (2014) UK and European Union public and charitable funding from 2008 to 2013 for bacteriology and antibiotic research in the UK: an observational study. Lancet Infectious Disease, 14(9):857-868. DOI: 10.1016/S1473-3099(14)70825-4.
