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Scientists from Newcastle University have solved the first de novo crystal structure of a protein using diffraction data from Diamond Light Source. The researchers successfully crystallised a protein called RsbS from the bacterium Moorella thermoacetica, and solved the crystal structure to 2.5 Å resolution.
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What does the future look like for UK Light Sources? Diamond may only just have gone into operation, but experts are already looking at the next generation of light sources. Following an independent review, a consultation project is now underway to develop a clear strategic vision for light sources that defines the needs of the scientific community in the decades to come.
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In alignment with the themes set by the national body Science Learning Centres, and in response to the Public Attitudes to Science 2008 government report (PAS report) published on 11th March, Diamond plans to engage with the public by building a programme around three areas.
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Construction has begun on the latest addition to the UK’s world class new research facility, Diamond Light Source. The Joint Engineering, Environmental and Processing (JEEP) beamline will be the first experimental station to extend outside of the main building to enable large engineering components to be placed under Diamond’s powerful X-ray beam.
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On 30th January 2008, Beamline B16 was pleased to welcome its first users: Professor Moreton Moore, Professor Victor Petrashov and Dr Rais Shaikhaidarov from Royal Holloway, University of London. B16 is a flexible and versatile beamline for testing new developments in X-ray optics and detector technology and for trialling new experimental techniques. It is the ninth Diamond beamline to welcome users.
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Metal oxyhydroxide nanoparticles form in many natural (e.g. rivers) and contaminated land environments. These mineral particles are an important part of the global iron cycle and, due to their high surface reactivity, adsorb large amounts of dissolved species onto their surfaces and into their structures during formation. These processes significantly influence the distribution, speciation and bioavailability of trace elements in many natural systems. This is particularly relevant in ...
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Thin films produced by depositing pre-formed size-selected gas-phase nanoparticles are an important class of materials, particularly because of their application in magnetic memory.
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Zeolites are important nanoporous materials with many applications, including use in laundry detergents, as industrial catalysts and for cleaning up nuclear waste. Zeolites have a cage-like structure which enables them to trap charged particles called cations. Scientists from the University of Birmingham have been using Diamond to investigate new ways of locating cations and nanoparticles within different types of zeolites, this is important in order to understand and improve their use.
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In the UK, a parliamentary House of Lords Select Committee is undertaking an inquiry into the effectiveness of action by intergovernmental organisations to control the spread of infectious diseases.
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Diamond Light Source, the UK's world-class synchrotron facility, has welcomed the first users to its new Test beamline. Researchers from Royal Holloway, University of London, have used the Diamond synchrotron to take a closer look at industrial diamonds as a means to test their latest collimator technology.
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Scientists from the Mary Rose Trust are using cutting edge synchrotron technology at Diamond Light Source to provide 21st century solutions to enhance the conservation of Henry VIII’s Tudor warship.
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Thin films produced by depositing pre-formed size-selected gas-phase nanoparticles are an important class of materials, particularly because of their application in magnetic memory. A team led by Chris Binns at the University of Leicester worked with the team on the Nanoscience beamline to study the magnetic properties of Fe thin films produced by this technique and compared them to Fe thin films produced by conventional techniques. Their results have been published in the Journal of ...
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Tuberculosis is a major cause of death worldwide, killing over 1.5 million people each year. Understanding how the bacterium Mycobacterium tuberculosis causes disease in humans and how it survives in the body could provide the key to combating this killer disease. Scientists from the Universities of Oxford and British Columbia have used Diamond to determine the structure of a protein called HsaD, which enables the tuberculosis bacteria to survive in the human body. Knowing the structure of ...
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Tuberculosis is a major cause of death worldwide, killing over 1.5 million people each year. Understanding how the bacterium Mycobacterium tuberculosis causes disease in humans and how it survives in the body could provide the key to combating this killer disease. Scientists from the Universities of Oxford and British Columbia have used Diamond to determine the structure of a protein called HsaD, which enables the tuberculosis bacteria to survive in the human body.
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Following recent factually inaccurate media reports, we would like to provide clarification regarding expenditure relating to Diamond’s construction and operational budgets.
Diamond’s Phase I construction concluded at the end of December 2006 and was delivered within the approved budget of £263.2m including contingency.
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The The Rt. Hon, John Denham (Secretary of State for Innovation, Universities and Skills) and Mr Ian Pearson (Minister for Science and Innovation) visited the UK's new synchrotron facility as part of a visit to the Harwell Science and Innovation Campus, where Diamond Light Source is part of the growing research community.
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John Denham, Secretary of State for Innovation, Universities and Skills, will today present an honorary CBE to Professor Gerhard Materlik, Chief Executive of Diamond Light Source Ltd for services to science.
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Nerves and blood vessels grow to the right places because they receive instructions to keep them on the correct path. These instructions come from pairs of molecules: receptors and ligands on the surface of different cells. When a matched pair makes contact in a specific ‘handshake’ it directs the cell carrying the receptor right or left, just like SatNav. If we understand what different handshakes look like, we can design drugs that to strengthen them – to help nerve regeneration, or stop ...
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Aurora-A is an essential enzyme which is required for human cells to multiply. Aurora-A has higher activity than normal in many human cancers and is a target for the development of anti-cancer drugs, some of which are in clinical trials. X-ray crystallography is used to characterise how these small molecules interact with Aurora-A, and these data provide information on how they work and allow the production of a new generation of more potent inhibitors.
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Over one hundred members of the Oxfordshire Federation of Woman’s Institutes (WI) gathered together at Diamond Light Source this week to mark the finale of one of the largest art/science projects in the UK.
