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  • > Diamond and Thermo Fisher have joined forces to provide dedicated microscopes and cryo-EM services for industry.
  • Case Studies - How our clients have used synchrotron light in their research
  • > Synchrotron tomography explains observed dissolution variation in multi-particulate drug product batches
  • > A dedicated facility for industrial cryo-EM

Synchrotron Services for Industrial Scientists

Welcome to the Industrial Liaison Office. We are a group of specialist scientists with a diverse range of expertise, all dedicated to supporting scientists and researchers from a variety of industries access the facilities here at Diamond. The team has an assorted range of backgrounds and each member is a specialist in a different technique. We are therefore able to provide a multi-disciplinary approach to solving research and development problems.

To find out more about how we can help with your project, please select from the following options:

Alternatively you can search by the technique you are interested in, the industry sector you are from or simply find out more about the service we can offer by clicking one of the links below.

RESEARCH TECHNIQUES RESEARCH AREAS INDUSTRY SERVICES

 

Featured Case Studies

Understanding the failure mechanisms of electrospun fibres

The Problem profilephoto

The process of electrospinning has been around for many years. It was originally used for the development of textiles; however in the last 5-10 years, this method has been used for more innovative applications.

Electrospinning uses electric forces to draw charged threads of polymer solutions or polymer melts to create fibres with diameters of a few micrometres. It enables the generation of constructs with large surface areas and a fibrous morphology that closely resemble the macromolecular structure of many tissue matrices; it therefore provides a good structure for cell attachment, tissue regeneration, and even drug delivery.

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Pfizer - Visualising coating integrity for bead drug products

The Problem profilephoto

Drug products in the pharmaceutical industry are commonly prepared in the form of discrete multi-particulate units. Bead products are a vehicle used in the development of controlled release drugs and are prepared by coating an inert spherical core with multiple layers, including that of the active ingredient. Components in each applied layer can have a significant impact on how the drug will be released and porosity of the layers is a critical feature related to observed dissolution behaviour. However accurate and highly resolved measurement of the physical integrity of these layers is a significant challenge in the development of advanced multi-particulate dosage forms. 

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Personalising alendronate therapy when treating Osteoporosis

The Problem profilephoto

Osteoporosis is a bone disease that affects 200 million people worldwide and contributes to 8.9 million fractures annually. The condition causes a loss of bone mass and structure which in turn leads to bones becoming weak and breaking, usually during a trip or fall. The disease is prevalent in people over 55, and in particular women, due to the loss of oestrogen hormone during the menopause. Osteoporosis is becoming increasingly prevalent in men who receive cancer therapies which supress testosterone levels. Bisphosphonates are a family of medicines which are commonly prescribed to treat osteoporosis. The most common types are alendronate and zoledronate which aim to strengthen osteoporotic bones by slowing down the activity of bone cells.

Read more...

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Industrial Liaison Group:
Tel: +44 (0) 1235 778797

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Take a look at our event schedule for further details.

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  • Oct 10, 2018
    Understanding the failure mechanisms of electrospun fibres

    Understanding the failure mechanisms of electrospun fibres

    A recent collaborative study looks at the tensile deformation of electrospun fibrous materials to understand their failure mechanisms under stress.

  • Sep 24, 2018
    eBIC for Industry

    eBIC for Industry

    In our Spotlight on eBIC for industry we will review some of the new opportunities that this technique can offer to the biopharma sector. Read ...

  • Sep 11, 2018
    Cryo-EM for Industry

    Cryo-EM for Industry

    Cryo-EM is a research technique used to determine the structure of biological macromolecules and assemblies. It is a very effective method for ...