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Macromolecular crystallography offers important insights into an ancient family of enzymes.
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eBIC was used to determine the first structure of a DNA crosslink repair E3 ligase
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Engineers at Diamond developed an acoustic levitation system for sample delivery to improve MX experiments
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Facilities like Diamond Light Source help to address and promote cutting-edge earth science research, helping to act as an agent of change for 21st century geoscience challenges.
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Using I12 to virtually unwrap 2,000 year old scrolls in the hope they will provide new insights into the ancient world.
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Worldwide scientific collaboration creates simple ways to get metal nanoparticles under control and substantially reduce the cost of making catalysts for the production of everyday goods like fertilisers, pharmaceuticals and liquid fuels like petrol.
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Macromolecular crystallography on I24 shines a light on a new way to target the malaria parasite
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A new 6M€ grant is being launched for the Photon and Neutron Data Services (ExPaNDS) to come together and work under the European Open Science Cloud (EOSC).
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Diamond Light Source has been welcomed as the twelfth member of The Rosalind Franklin Institute (The Franklin), close neighbours on Harwell Campus.
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The structure shows how the protein works and provides a new drug target
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Pirbright has granted an exclusive commercial licence for a vaccine to protect livestock against foot-and-mouth-disease-virus (FMDV)
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X-ray microtomography at Diamond generates 3D images of bumblebee eyes and explores effect of size on vision.
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annual review
Acute myeloid leukaemia (AML) is a rapid and often fatal disease. The disease originates in the body’s system for producing white blood cells, where diseased AML cells (in common with many other types of cancer) will interfere with healthy human cytotoxic lymphoid cells, the body’s natural defence system against cancerous cells.
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annual review
Using Diamond Light Source’s Small Angle Scattering & Diffraction beamline (I22), I911-SAXS at MAX IV Laboratory, SWING at SOLEIL synchrotron, and P12 at EMBL BioSAXS, a team of researchers from Tel Aviv University and the Technion-Israel Institute of Technology mapped, for the first time, the delicate and complicated force balance between the myelin sheath constituents and their effect on the myelin structure.
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annual review
Analysing cells on a cell-by-cell basis using infrared microspectroscopy can reveal important biochemical information, providing insight into diseases, and drug-cell interactions. However, for visible and infrared microscopy, the cells have to be preserved and dried; also, water is a strong infrared absorber and obscures the spectrum of the cells under investigation.
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annual review
Diesel is the fuel of choice for heavy goods vehicles, but diesel combustion generates nitrogen oxides (NOx) that are known to be harmful to human health;
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annual review
Some of the most effective cancer treatments involve platinum-based drugs, but resistance to platinum compounds is increasing and there is an urgent need to find alternatives. A team from the University of Warwick has discovered a new osmium-based (Os-based) anti-cancer agent, FY26, which exhibits high potency against a range of cancer cell lines and is capable of overcoming platinum resistance. Before it can be tested in clinical trials, the team needs to understand fully how it works.
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annual review
The increasing energy storage needs of electric vehicles and mobile devices is driving research into higher performance batteries. One particular challenge for some applications is safely charging/discharging fast enough, and most materials that offer both high power and fast charging require nanoparticles that are expensive to make and difficult to produce in large quantities.
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An international research team from the University of Cambridge, Diamond Light Source and the Advanced Photon Source have been awarded the 2019 Charles Hatchett Award.
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annual review
Hexaferrites are an important class of magnetic oxides with applications in data storage and electronics, and have been the subject of numerous studies since their discovery in the 1950s.