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  1. Diamond Light Source
  2. News and Literature
  3. Annual Review
  4. Diamond Annual Review 2019
  5. Science Group Updates
  6. Crystallography Group

Crystallography Group

  • annual review
    Sweet Success: Crystal structure of the full-length GLP-1 receptor bound to a peptide agonist

    Sweet Success: Crystal structure of the full-length GLP-1 receptor bound to a peptide agonist Jun 1, 2018

    To design such small molecules, a detailed map of the interactions between GLP-1 and its receptor was needed.

  • annual review
    Structural insights into the mechanism of bacterial ABC transporters

    Structural insights into the mechanism of bacterial ABC transporters Jun 1, 2018

    Bacteria utilise ATP-binding cassette (ABC) transporters to import nutrients and detoxify themselves. These transporters have been shown to exist in wide open conformations that permit the access of many substrates in the binding pocket.

  • annual review
    Structure of the surface layer surrounding Caulobacter crescentus bacteria

    Structure of the surface layer surrounding Caulobacter crescentus bacteria Jun 1, 2018

    Many types of single-celled microorganisms such as bacteria are covered with a protective outer layer of proteins known as the S-layer.

  • annual review
    How does an inspector call: structures of UGGT, the eukaryotic glycoprotein quality control checkpoint.

    How does an inspector call: structures of UGGT, the eukaryotic glycoprotein quality control checkpoint. Jun 1, 2018

    In all cells derived from animals, plants, fungi and protozoa a single protein called UGGT acts as a quality control checkpoint that inspects secreted glycoproteins.

  • annual review
    Insights into the mechanism of colistin resistance from crystal structures of MCR-1

    Insights into the mechanism of colistin resistance from crystal structures of MCR-1 Jun 1, 2018

    Gram-negative bacteria that are extensively resistant to multiple antibiotics are an ever-increasing global threat. Colistin is an antibiotic used as the last line of defence against highly resistant Gram-negative bacteria. However, in recent years bacteria have emerged with resistance to this crucial antibiotic.

  • annual review
    How human endoglin captures its ligand BMP9

    How human endoglin captures its ligand BMP9 Jun 1, 2018

    Endoglin (ENG)/CD105 is a mammalian glycoprotein that is found in the membranes of cells that line blood vessels. It is essential for healthy heart development and blood vessel growth, but conversely it is also involved in preeclampsia and can help tumours establish their blood supply.

Joe Hriljac, Science Group Leader

The Crystallography Science Group comprises the High Resolution Powder Diffraction beamline (I11), the Extreme Conditions beamline (I15), the X-ray Pair Distribution Function (XPDF) beamline (I15-1), and the Small-Molecule Single-Crystal Diffraction beamline (I19). Bringing these beamlines together into one science group means we can fully exploit the technical and scientific expertise within its teams to provide the basis for future development and pioneering experiments. The coming year will see many beamline upgrade projects, with the aim to further develop our tools, data analysis pipelines and strategic planning for the Diamond-II upgrade. Read more ...

  • annual review
    Solving the single-crystal structure of mixed-layer hexaferrites, for potential use in data storage

    Solving the single-crystal structure of mixed-layer hexaferrites, for potential use in data storage Aug 2, 2019

    Hexaferrites are an important class of magnetic oxides with applications in data storage and electronics, and have been the subject of numerous studies since their discovery in the 1950s.

  • annual review
    Mixing advanced materials to make hybrid glasses

    Mixing advanced materials to make hybrid glasses Aug 2, 2019

    Metal-organic frameworks (MOFs) are a class of crystalline materials with a structure of inorganic nodes connected by organic ligands.

  • annual review
    Elastic porous crystals

    Elastic porous crystals Aug 2, 2019

    Over the past few years, responsive materials - materials that change their structure when chemical, thermal, or mechanical stimuli are applied - have been studied extensively. A team of researchers used high-pressure X-ray diffraction on the Extreme Conditions beamline (I15) to study stimuli-responsive metal-organic frameworks (MOFs), a class of synthetic, crystalline, and porous materials constructed from organic and inorganic building units. Some MOFs are known to be flexible, and to ...

  • annual review
    Understanding the origin of poor cycling stability in novel high capacity Li-ion battery materials: A long duration study

    Understanding the origin of poor cycling stability in novel high capacity Li-ion battery materials: A long duration study Aug 2, 2019

    Climate change, dwindling supplies of fossil fuels, and growing environmental awareness are all contributing to a surge of interest in electric vehicles. However, battery-powered electric vehicles cost more, and have a shorter range, than petrol/diesel vehicles, due to the energy density of lithium-ion batteries, for which cathode materials are currently a limiting factor.

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Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.

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