• Diamond Home page
  • About
  • For Users
  • Public
  • Industry
  • Instruments
  • Careers
  • More Show more menu items
Search

About

  • About Diamond
  • About Synchrotrons
  • News and Features
  • Events
  • Contact Us
  • FAQ

For Users

  • Apply for beamtime
  • User guide
  • Diamond Users Commitee
  • FAQ
  • User Administration System
  • iSpyB

Industry

  • Techniques Available
  • Industry Research
  • Industry Case Studies
  • News
  • Meet the Industry Team

Science

  • Research
  • Computing
  • The Machine
  • Publications
  • Research Expertise
  • Membrane Protein Laboratory
  • Additional Facilities
  • Publications Database

Instruments

  • Biological Cryo-Imaging
  • Crystallography
  • Imaging and Microscopy
  • Macromolecular Crystallography
  • Magnetic Materials
  • Soft Condensed Matter
  • Spectroscopy
  • Structures and Surfaces

Diamond-II

  • Science
  • Machine
  • Beamlines
  • Software, Control and Computing
  • Infrastructure

Public

  • Public open days
  • School visits
  • Partner with Diamond
  • Explore Diamond

Procurement

  • Non-OJEU Tender Notices
  • OJEU PINs
  • OJEU Tender Notices
  • Registration Form

Careers

  • Vacancies
  • Info for applicants
  • Company Benefits
  • Apprenticeships
  • PhD Studentships
  • Work Placement

Main Content

A brighter light for science
Sub-navigation
  • About
  • Governance
  • Legal and Compliance
  • News and Literature
  • Events
  • Contact

In This Section

Sub Navigation
  • News and Science Highlights
  • Annual Review
  • Literature Reviews
  • Impact Case Studies
  • Press and media

Opportunities at Diamond

Learn more about career and student opportunities at Diamond:

Vacancies

Students

  1. Diamond Light Source
  2. News and Literature
  3. Annual Review
  4. Diamond Annual Review 2018
  5. Science Group Updates
  6. Soft Condensed Matter Group

Soft Condensed Matter Group

  • annual review
    Sweet Success: Crystal structure of the full-length GLP-1 receptor bound to a peptide agonist

    Sweet Success: Crystal structure of the full-length GLP-1 receptor bound to a peptide agonist Jun 1, 2018

    To design such small molecules, a detailed map of the interactions between GLP-1 and its receptor was needed.

  • annual review
    Structural insights into the mechanism of bacterial ABC transporters

    Structural insights into the mechanism of bacterial ABC transporters Jun 1, 2018

    Bacteria utilise ATP-binding cassette (ABC) transporters to import nutrients and detoxify themselves. These transporters have been shown to exist in wide open conformations that permit the access of many substrates in the binding pocket.

  • annual review
    Structure of the surface layer surrounding Caulobacter crescentus bacteria

    Structure of the surface layer surrounding Caulobacter crescentus bacteria Jun 1, 2018

    Many types of single-celled microorganisms such as bacteria are covered with a protective outer layer of proteins known as the S-layer.

  • annual review
    How does an inspector call: structures of UGGT, the eukaryotic glycoprotein quality control checkpoint.

    How does an inspector call: structures of UGGT, the eukaryotic glycoprotein quality control checkpoint. Jun 1, 2018

    In all cells derived from animals, plants, fungi and protozoa a single protein called UGGT acts as a quality control checkpoint that inspects secreted glycoproteins.

  • annual review
    Insights into the mechanism of colistin resistance from crystal structures of MCR-1

    Insights into the mechanism of colistin resistance from crystal structures of MCR-1 Jun 1, 2018

    Gram-negative bacteria that are extensively resistant to multiple antibiotics are an ever-increasing global threat. Colistin is an antibiotic used as the last line of defence against highly resistant Gram-negative bacteria. However, in recent years bacteria have emerged with resistance to this crucial antibiotic.

  • annual review
    How human endoglin captures its ligand BMP9

    How human endoglin captures its ligand BMP9 Jun 1, 2018

    Endoglin (ENG)/CD105 is a mammalian glycoprotein that is found in the membranes of cells that line blood vessels. It is essential for healthy heart development and blood vessel growth, but conversely it is also involved in preeclampsia and can help tumours establish their blood supply.

Update

The Soft Condensed Matter Group provides the infrared (IR) and Circular Dichroism (CD) spectroscopy and, both Small and Wide Angle X-ray Scattering (SAXS and WAXS) imaging capabilities of Diamond. The Soft Condensed Matter Group comprises of four beamlines B21, B22, I22 and B23. This unique portfolio of beamlines can analyse a range of samples that include two-dimensional thin films (photovoltaics), living mammalian cells, three-dimensional matrices (metal-organic frameworks) and nano-particles in non-crystalline states. Read more ...
  • annual review
    Unravelling the mechanisms of immune escape by acute myeloid leukaemia

    Unravelling the mechanisms of immune escape by acute myeloid leukaemia Jun 1, 2018

    Acute myeloid leukaemia (AML) is a type of blood cancer that originates from white blood cells in the bone marrow. It is often fatal and is considered one of the most common cancers of children and the elderly. The high mortality rate associated with this cancer can partly be ascribed to ineffective current treatments, which consist of aggressive chemotherapy and stem cell transplantation. There is a great need to find alternative treatments for AML patients to improve their outcomes. By ...

  • annual review
    Shocking protein crystals into action: combining electrochemistry and infrared microscopy provides insight into [NiFe] hydrogenase mechanism

    Shocking protein crystals into action: combining electrochemistry and infrared microscopy provides insight into [NiFe] hydrogenase mechanism Jun 1, 2018

    Proteins are the nanoscale ‘machines’ that control almost all processes in cells, and revealing their structures is paramount to understanding how they work. X-ray crystallography is a valuable tool for providing ‘snapshot’ images of working proteins at an atomic level; however, some proteins are very tricky to freeze at particular moments in time.

  • annual review
    Building 3D nanomaterials with sticky DNA bricks

    Building 3D nanomaterials with sticky DNA bricks Jun 1, 2018

    Several technological applications, spanning from energy storage to biomedicine, require the preparation of new materials with a finely organised 3D nanoscale structure. To achieve such delicate structures, they must be assembled from the bottom up, much like the iconic Lego bricks. However, unlike Lego, the building blocks in these scenarios are too small to be handled directly, so they must be encouraged to self-assemble.

  • annual review
    Complex Self-assembly Inside Atmospheric Aerosol Droplets?

    Complex Self-assembly Inside Atmospheric Aerosol Droplets? Jun 1, 2018

    Aerosols are significant to the Earth’s climate, with nearly all atmospheric aerosols containing organic compounds that often contain amphiphilic molecules. However, the nature of how these compounds are arranged within an aerosol droplet remains unknown. It was recently demonstrated that fatty acids in proxies for atmospheric aerosols self-assemble into highly ordered three-dimensional nanostructures known as lyotropic liquid crystalline phases. This finding may have implications for ...

  • Contact Us
  • About Diamond Light Source
  • Procurement
  • Supply Chain Transparency
  • Cookie Policy
  • Website Terms of Use
  • Privacy Notice

Diamond Light Source

Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.

Follow us on Facebook Follow us on Linkedin Follow us on Instagram Follow us on Bluesky

Diamond Light Source Ltd
Diamond House
Harwell Science & Innovation Campus
Didcot
Oxfordshire
OX11 0DE

See on Google Maps

Copyright © Diamond Light Source. Diamond Light Source® and the Diamond logo are registered trademarks of Diamond Light Source Ltd

Registered in England and Wales at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom. Company number: 4375679. VAT number: 287 461 957. Economic Operators Registration and Identification (EORI) number: GB287461957003.

feedback