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As Diamond matures, the expansion and development of expertise and complementary facilities have become increasingly important to both our academic and industrial users. The Industrial Liaison service offer for integrated structural biology provides a synergistic approach, where our clients can access both world leading technology and talent across Macromolecular Crystallography (MX), fragment based drug discovery, Small Angle X-ray Scattering (SAXS) and cryo-electron microscopy (cryo-EM) techniques. Co-location of these advanced characterisation facilities at Diamond, supported by expert staff, leads to rapid technique development, streamlined sample handling processes and increased opportunities for innovation in all fields.
Cryo-EM in particular is an area of growth, as the popularity of the technique as an alternative route to high resolution structural information from hard-to-crystallise systems is rapidly increasing, far outstripping the availability of high-end microscopes. Few structural biology groups in industry yet have access to their own instruments, and specialist expertise is needed to fully exploit the power of the technique. Access to Diamond’s industrial cryo- EM service can therefore provide expert advice on experiment design, sample preparation, data collection and analysis; ideal for those starting out with cryo-EM or experienced users with complex problems to solve.
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
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