The aims of this workshop are to introduce Diamond-II, to discuss its potential benefits for the existing facilities, and to develop the science case for the machine upgrade.
There are a number of hotels and bed-and-breakfast options in the immediate vicinity of Diamond.
Prices per night will vary. Please enquire directly with your hotel of choice for details.
Hotels within a short driving distance of Diamond include:
Diamond is approximately 30 minutes drive from Oxford city centre which has a wide range of hotels and accommodation options.
Day 1: MX Workshop - 10th September
| 09:45 | Registration | |
| Session 1: Opportunities of the Diamond-II upgrade for MX beamlines | ||
| 10:30 | D-II and Grand Challenges | Dave Stuart (DLS, Oxford) |
| 10:55 | D-II Impact for MX beamlines | Dave Hall (DLS) |
| 11:20 | XChem and beamline move | Frank von Delft (DLS, Oxford) |
| 11:45 | Bang for your buck - getting the best data with D-II | Gwyndaf Evans (DLS) |
| 12:10 | Lunch | |
| 13:10 | The future of cryo-samples - automation and streamlining | Katherine McAuley (DLS) |
| 13:35 | Future of phasing and exploiting tuneability | Armin Wagner (DLS) |
| 14:00 | Discussion | |
| 14:30 | Coffee | |
| Session 2: Serial crystallography and time resolved experiments | ||
| 15:00 | Introduction to Serial crystallography | Robin Owen (DLS) |
| 15:15 | Opportunities for rapid and time resolved serial crystallography | Mike Hough (University of Essex) |
| 15:40 | What does D-II mean for the XFEL-Hub | Allen Orville (DLS) |
| 16:05 | MX at SLS and SwissFEL | Meitian Wang (Paul Scherrer Institut) |
| 16:30 | Discussion | |
| 17:00 | Coffee | |
| Session 3: Structural biology needs for the future | ||
| 17:25 | Elucidating mechanism of biotechnologically relevant enzymes, the need for time resolved approaches | Colin Levy (University of Manchester |
| 17:50 | TBA | Susan Lea (University of Oxford) |
| 18:15 | Discussion | |
| 19:00 | Dinner | |
| 09:45 | Registration | |
| 10:30 | SCM beam line introduction | Rob Rambo (DLS) |
| 10:45 | I22 | Nick Terrill (DLS) |
| 11:05 | B23 | Giuliano Siligardi (DLS) |
| 11:25 | B22 | Gianfelice Cinque (DLS) |
| 11:45 | B21 | Nathan Cowieson (DLS) |
| 12:05 | Lunch | |
| 13:00 | SAXS tomography | TBA |
| 13:20 | CD MMP for imaging | Bart Kahr (NYU) |
| 13:40 | nano IR tomography | Luca Quaroni (Jagiellonian University, Poland) |
| 14:00 | THZ MOF | Jin-Chong Tan (University of Oxford) |
| 14:20 | Discussion | |
| 14:50 | Coffee | |
| 15:20 | Applications of Microfluidics on I22 | TBA |
| 15:40 | Applications of Microfluidics on B23 | Jerome Charmet (Warwick University) |
| 16:00 | Applications of Microfluidics on B22 | Russel Howe (Aberdeen University) |
| 16:20 | SOLEIL microfluidics | Benedikt Lassalle (SOLEIL) |
| 16:40 | Discussion | |
| 17:10 | Coffee | |
| 17:30 | XFMS | Peter Stockley (Lees U)/Sayan Gupta (ALS) |
| 17:50 | TBA | |
| 18:10 | B22 In situ time-resolved electrochemistry and correlated IR molecular analysis (faster and signal-to-noise) | Kylie Vincent (University of Oxford) |
| 18:30 | IR imaging and correlative studies | Rohit Bhargava |
| 18:50 | Discussion | |
| 19:00 | Dinner | |
| Session 1: High throughput methods and drug discovery | ||
| 09:00 | High-Throughput Methods and Drug Discovery Introduction | Dave Brown (University of Kent) |
| 09:10 | MPS1 inhibitors and the molecular basis of resistance to MPS1 inhibition | Rob van Montfort (ICR) |
| 09:35 | Drug Discovery an industrial perspective | Rob Cooke (Heptares) |
| 10:00 | Protein Engineering/Ligand Screening SAXS | Greg Hura (ALS, Berkeley) |
| 10:25 | Coffee | |
| 10:55 | CD based screening method | Lorenzo Di Bari (Pisa U.) |
| 11:20 | High-throughput GI-SAXS | Alex Hexemer(ALS, Berkeley) |
| 11:45 | Discussion | |
| 12:15 | Lunch | |
| | Data deluge | |
| 13:15 | Data handling at Diamond | Andrew Richards (DLS) |
| 13:40 | Data analysis for integrated biology at Diamond | Alun Ashton (DLS) |
| 14:05 | Data mining science | A Hexemer (ALS, Berkeley) |
| 14:30 | Discussion | |
| 15:00 | Coffee | |
| | Broader topics | |
| 15:30 | X-ray crystallography of large complexes in the age of cryo-EM | Ashwin Chari (Max Planck, Gottingen) |
| 15:55 | The ESRF upgrade - impact on MX and SAXS for users | Jean Susini (ESRF) |
| 16:20 | Mono and Pink beam SSX and Life Science with APS-U | Bob Fischetti (APS, Chicago) |
| 16:45 | Discussions and Conclusions | |
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