BCA-CCP4 Summer School

Aug 27. till Sep 01.

BCA/CCP4 Summer School

A week long residential course, the BCA - CCP4 Protein Crystallography Summer School is intended to provide students and researchers with an introduction to crystallography.

Date
27/08/20182018-08-27 - 01/09/20182018-09-01
Location
Diamond Light Source, Oxfordshire, UK

BCA/CCP4 Summer School in Protein Crystallography

Monday 27th August - Saturday 1st September 2018

The BCA/CCP4 Protein Crystallography Summer School is intended for students and researchers new to crystallography. Its dual aims are to provide comprehensive training in crystallography and to promote best practise within the British crystallographic community. The lectures cover the gamut of techniques required for a structure solution, from protein expression through to structure validation. Intensively supervised computer tutorials enable students to relate the theory presented in the lectures to practice. Although CCP4 programmes will primarily be used in these tutorials, the aim will be to approach crystallographic questions in a software-agnostic manner. There will also be a crystal manipulation and cooling workshop. (Note that the course is scheduled during Diamond synchrotron downtime, so there will not be active data collection at the Diamond beamlines).

If you have any further questions, please contact our events team on events@diamond.ac.uk or 01235 778384
 

Eligibility

Postgraduate students should have started their research degree in or before October 2017.

All applicants will require a letter of support from their supervisor.

Cost

Registration fees for attendees are kept well below cost price thanks to substantial resources allocated to bursaries, a grant from CCP4 and generous donations from our sponsors.

Sucessful applicants holding a BBSRC funded PhD studentship will have their registration fee covered by the BBSRC.

The cost of the school, including full board, will be 360 GBP (includes VAT). 

Application

Before beginning the application process please prepare your CV/resume including a description of your crystallographic experience, other skills, and why you want to attend the course. You should also confirm in advance that the person you nominate as your referee will support your application, because your referee will be sent an email automatically as soon as you submit your application.

We will allocate places on the grounds of merit and anticipated benefit to the student.

Accepted Students will be required confirm they will attend the whole course (no late arrivals or early departures).

KEY DATES

Applications are now closed.  For all queries email events@diamond.ac.uk 

Applications deadline -   extended to 25th May 

References due by - 1st June 2018

Venue

The course is residential, with accommodation provided at Ridgeway Guest House on the Harwell Science and Innovation Campus.

Lectures and tutorials will take place at Diamond Light Source. 

The crystal manipulation and cooling workshop will be held at the Research Complex at Harwell (located next to the Diamond synchrotron).

Programme- BCA/CCP4 Protein Crystallography Summer School 2018

DOWNLOAD PROGRAMME HERE

 

 Monday 27th August 2018

15:00
Arrival and registration
16:00
Welcome
16:10
Talk: Crystallography
16:30
Student Stories
18:30
Dinner
19:30
Student Stories
21:30
Drinks
 
Tuesday 28th August 2018
 
7:30
Breakfast
9:00
Lecture: Crystallization
9:45
Lecture: Diffraction  
10:30
Coffee
11:00
Lecture: Crystal Preparation for Cryocrystallography
11:45
Lecture: Fourier Transform
12:30
Lunch
13:30
Lecture: Symmetry and Space Groups
14:15
Lecture: Space Group Determination
15:30
Tea
16:00
Social Event in Oxford
 
Wednesday 29th August 2018
 
7:30
Breakfast
9:00
Lecture: Data Collection
9:45
Lecture: Data Scaling and Merging
10:30
Coffee
11:00
Practical: Data Processing
12:30
Lunch
13:30
Lecture: Pattersons
14:00
Lecture: Models for Molecular Replacement
14:30
Lecture: Molecular Replacement
15:30
Tea
16:00
Practical: Molecular Replacement
19:00
Dinner
20:00
Guest Lecture
 
Thursday 30th August 2018
 
7:30
Breakfast
9:00
Lecture: Maximum likelihood with Dice
9:45
Lecture: Preparation of Derivatives
10:30
Coffee
11:00
Lecture: Finding Heavy Atom Sites
11:30
Lecture: Experimental Phasing MAD/SAD
12.30
Lunch
13:30
Lecture: Phase Improvement and Model Building
15:00
Tea
15:30-18:00
Practical: Your own data or
                Complete previous practical or
                 MAD/MIR Phasing with phenix
19:00
Dinner
20:00
Movie: The Double Helix
 
Friday 31st August 2018
 
7:30
Breakfast
9:00
Lecture: Refinement
10:30
Coffee
11:00
Lecture: Validation
12:30
Lunch
13:30
Lecture: Radiation Damage
14:15
Lecture: Twinning
15:30
Tea
16:00
Practical: Model Building, Refinement and Validation
19:30
Conference Dinner with Guest Speaker
 
 
Saturday 1st September 2018
 
7:30
Breakfast
9:30
Lecture: Graphics and Representations
10:15
Quiz Questions
10:30
Coffee
11:00
Lecture: NMR
11:45
Lecture: Experiment Management
12:30
Lunch
13:30
Lecture: Electron Microscopy
14:30
Quiz Answers
15:00
Close

Social Programme

We recognise that the social programme plays a role in enabling students to make links that may be maintained throughout a research career. There will be a conference dinner, and a number of other events, including a trip to Oxford.