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XChem: X-ray structure-accelerated, synthesis-aligned fragment medicinal chemistry
Fragment-based lead discovery is a drug discovery process that has revolutionised the pharmaceutical industry, providing valuable and cost-effective insights for rational drug design in the early stages. Rather than focusing on a few large complex compounds, it explores a larger part of the existing chemical space from the drug targets of interest, providing new entry routes for the development of lead compounds.
Here at Diamond, our world-class facilities provide a streamlined, secure and effective route to fragment screening. With the co-location of the XChem laboratory and the I04-1 beamline, we can significantly reduce the time to structural determination. Our unique processes, tailored software, and automated systems enable us to record and track your data seamlessly from initial crystal cultivation through to data analysis. Throughout your research, our expert scientists are on hand to advise, train and support you in every step of your journey.
XChem at Diamond
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
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