Structural biology enables scientists to look in detail at the structure and behaviour of cells and their macromolecular components, such as proteins and nucleic acids. To do so requires very powerful analytical tools to capture high resolution information and uncover details about biological function, the effect of disease or genetic variations and explore how these can be modified through the use of pharmaceutical drugs.
X-ray crystallography remains a key tool for the characterisation of macromolecules, small molecules, complexes and ligand binding, while complementary techniques such as electron microscopy, and small angle X-ray scattering are increasingly leading to a more complete understanding of the process in question.
Here at Diamond we provide access to the very latest generation of microscopes and high performance crystallography instrumentation along with the expertise of our dedicated team of scientists. Our unique facility enables users to combine a range of approaches using multiple techniques, across one site. So whether your samples are in crystal form, in solution or in their native state, we can help you to determine the best techniques/or combination of techniques to meet your research needs.
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
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