About eBIC

The Electron Bio-Imaging Centre (eBIC) was established at Diamond following the award of a £15.6 million grant from the Wellcome Trust, the Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC). The location of eBIC enables scientists to combine their techniques with many of the other cutting-edge approaches that Diamond offers; whilst a partnership with the University of Oxford allows users to access the Polara, a high-containment cryo-electron microscope.

eBIC provides scientists with state-of-the-art experimental equipment and expertise in the field of cryo-electron microscopy, for both single particle analysis and cryo-tomography. Currently eBIC houses four Titan Krios microscopes, a Talos Arctica and a Scios cryo-FIB/SEM. The Polara microscope is located at the University of Oxford.

First session taken by a BAG super-user in eBIC's new control room

First BAG super-user led session from the University of Oxford.
First BAG super-user led session from the University of Oxford.

In February 2018 work was completed on a new control room for remote control access to eBIC's four Krios microscopes. 

The new control room facilitates a more efficient way of working with the vast majority of eBIC activities able to be undertaken in the same building.  It also enables users to enjoy a more comfortable working environment when visiting eBIC. 
On 9th February 2018 the first candidates successfully completed BAG super-user accreditation, and are now able to enjoy greater flexibility during their user sessions. 


  • The eBIC team
  • The eBIC executive committee outside the building.
  • Alex Buzduga and Alistair Siebert with Krios I at Diamond.
  • A cryo EM map of Tobacco Mosaic Virus, with the atomic structure (colours) built into it.
  • Detail of the Adeno virus.
1 2 3 4 5

eBIC control room now fully operational for remote control access to all Krios microscopes.

Where: eBIC
Who: eBIC

First BAG super user accreditation/training successfully completed.


eBIC welcomes three new members of staff, Katie Cunnea (Centre coordinator) James Gilchrist (Support Scientist) and Zhengyi Yang (Postdoc).


CryoEM Sample Training workshop - 2nd - 4th October 

Open for applicaitions 


eBIC Director announced: Introducing Prof Peijun Zhang


Krios II welcomes its first users from the University of Oxford


Krios I welcomes first users from MRC LMB Cambridge


[Publication] A national facility for biological cryo-electron microscopy. Saibil, H. R., Grunewald, K. & Stuart, D. I. (2015). Acta Cryst. D 71, 127-135. DOI: 10.1107/S1399004714025280