These publications are based on data gathered on beamline I04. If you are aware of any errors or publications that should be listed here, please send details to Sara Fletcher.
Total: 214 publications
| Date∇ | Publication details∇ |
|---|---|
| February 2012 | Three-dimensional structure of a thermophilic family GH11 xylanase from Journal Paper, Alicia Lammerts van Bueren,Suzie Otani,Esben P. Friis,Keith S. Wilson,Gideon J. Davies, Acta Crystallographica Section F Structural Biology and Crystallization Communications 68 DOI: 10.1107/S1744309111049608 |
| February 2012 | An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid Journal Paper, Marc de la Roche,Trevor J. Rutherford,Deepti Gupta,Dmitry B. Veprintsev,Barbara Saxty,Stefan M. Freund,Mariann Bienz, Nature Communications 3 DOI: 10.1038/ncomms1680 |
| January 2012 | Structural and mechanistic insight into N-glycan processing by endo- -mannosidase Journal Paper, Andrew Thompson,R. J. Williams,Z. Hakki,D. S. Alonzi,T. Wennekes,T. M. Gloster,K. Songsrirote,J. E. Thomas-Oates,T. M. Wrodnigg,J. Spreitz,A. E. Stutz,T. D. Butters,S. J. Williams,G. J. Davies, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1111482109 |
| January 2012 | Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes Journal Paper, Anna Bulek,David Cole,Ania Skowera,Garry Dolton,Stephanie Gras,Florian Madura,Anna Fuller,John J Miles,Emma Gostick,David A Price,Jan W Drijfhout,Robin R Knight,Guo C Huang,Nikolai Lissin,Peter E Molloy,Linda Fothergill-Gilmore,Bent K Jakobsen,Jamie Rossjohn,Mark Peakman,Pierre J Rizkallah, Nature Immunology DOI: 10.1038/ni.2206 |
| January 2012 | Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands Journal Paper, Gavin Collie,Rossella Promontorio,Sonja M Hampel,Marialuisa Micco,Stephen Neidle,Gary Parkinson, Journal of the American Chemical Society DOI: 10.1021/ja2102423 |
| January 2012 | Structural insights into human Kif7, a kinesin involved in Hedgehog signalling Journal Paper, Marta Klejnot,Frank Kozielski, Acta Crystallographica Section D Biological Crystallography 68 DOI: 10.1107/S0907444911053042 |
| December 2011 | Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis Journal Paper, Apirat Chaikuad,D. S. Froese,G. Berridge,Frank von Delft,Udo Oppermann,Wyatt Yue, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1113921108 |
| December 2011 | Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis Journal Paper, Apirat Chaikuad,D. S. Froese,G. Berridge,Frank von Delft,Udo Oppermann,Wyatt Yue, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1113921108 |
| December 2011 | The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly Journal Paper, Nia L. Marrott,Jacqueline Marshall,Dmitri Svergun,Susan Crennell,David Hough,Michael Danson,Jean van den Elsen, FEBS Journal DOI: 10.1111/j.1742-4658.2011.08461.x |
| December 2011 | Dissection of the Network of Interactions That Links RNA Processing with Glycolysis in the Bacillus subtilis Degradosome Journal Paper, Joseph A Newman,Lorraine Hewitt,Cecilia Rodriguez,Alexandra Solovyova,Colin R. Harwood,Rick Lewis, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.12.024 |
| November 2011 | The crystal structure of Leishmania major N5,N10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase and assessment of a potential drug target Journal Paper, Tom Eadsforth,Scott Cameron,William Hunter, Molecular and Biochemical Parasitology DOI: 10.1016/j.molbiopara.2011.11.004 |
| November 2011 | HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase Journal Paper, David Goldstone,Valerie Ennis-Adeniran,Joseph J. Hedden,Harriet C. T. Groom,Gillian I. Rice,Evangelos Papagrigoriou,Phil Walker,Geoff Kelly,Lesley Haire,Melvyn Yap,Luiz Pedro S. de Carvalho,Jonathan Stoye,Yanick J. Crow,Ian Taylor,Michelle Webb, Nature DOI: 10.1038/nature10623 |
| November 2011 | A novel technique combining high-resolution synchrotron x-ray microtomography and x-ray diffraction for characterization of micro particulates Journal Paper, David Merrifield,Vasuki Ramachandran,Kevin J Roberts,Wes Armour,Danny Axford,Mark Basham,Thomas Connolley,Gwyndaf Evans,Katherine McAuley,Robin Owen,James Sandy, Measurement Science and Technology 22 DOI: 10.1088/0957-0233/22/11/115703 |
| November 2011 | Structure and Kinetic Stability of the p63 Tetramerization Domain Journal Paper, Eviata Najan,Andreas Christian Joerger, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.11.007 |
| November 2011 | Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor Journal Paper, Geoffrey Masuyer,Talat Jabeen,Christopher T. Öberg,Hakon Leffler,Ulf J. Nilsson,Ravi Acharya, FEBS Journal DOI: 10.1111/j.1742-4658.2011.08414.x |
| November 2011 | A Burkholderia pseudomallei Toxin Inhibits Helicase Activity of Translation Factor eIF4A Journal Paper, Abimael Cruz-Migoni,G. M. Hautbergue,P. J. Artymiuk,P. J. Baker,M. Bokori-Brown,C.-T. Chang,M. J. Dickman,A. Essex-Lopresti,S. V. Harding,N. M. Mahadi,L. E. Marshall,G. W. Mobbs,R. Mohamed,S. Nathan,S. A. Ngugi,C. Ong,W. F. Ooi,L. J. Partridge,H. L. Phillips,M. F. Raih, Science 334 DOI: 10.1126/science.1211915 |
| November 2011 | In silico screening reveals structurally diverse, nanomolar inhibitors of NQO2 that are functionally active in cells and can modulate NF B signalling Journal Paper, Karen A. Nolan,M. S. Dunstan,M. C. Caraher,K. A. Scott,David Leys,I. J. Stratford, Molecular Cancer Therapeutics DOI: 10.1158/1535-7163.MCT-11-0543 |
| November 2011 | Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation Journal Paper, Alex Gingras,Umakhanth Venkatraman Girija,Anthony H. Keeble,Roshni Panchal,Daniel A. Mitchell,Peter Moody,Russell Wallis, Structure 19 DOI: 10.1016/j.str.2011.08.014 |
| November 2011 | Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII Journal Paper, Martin Moncrieffe,Maria-Jose Fernandez,Dieter Spiteller,Hiroyoshi Matsumura,Nicholas Gay,Ben Luisi,Peter Leadlay, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.10.036 |
| November 2011 | PNAS Plus: Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales Journal Paper, Sonia Paytubi,Stephen McMahon,S. Graham,H. Liu,C. H. Botting,K. S. Makarova,Eugene Koonin,James Naismith,M. F. White, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1113277108 |
| November 2011 | Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation Journal Paper, Alex Gingras,Umakhanth Venkatraman Girija,Anthony H. Keeble,Roshni Panchal,Daniel A. Mitchell,Peter Moody,Russell Wallis, Structure 19 DOI: 10.1016/j.str.2011.08.014 |
| November 2011 | The Molecular Basis for the Endocytosis of Small R-SNAREs by the Clathrin Adaptor CALM Journal Paper, Sharon Miller,Daniela A. Sahlender,Stephen C. Graham,Stefan Honing,Margaret S. Robinson,Andrew A. Peden,David Owen, Cell 147 DOI: 10.1016/j.cell.2011.10.038 |
| October 2011 | Structure of New Delhi metallo-beta-lactamase 1 (NDM-1) Journal Paper, Vicky Green,Anil Verma,Raymond Owens,Simon E. V. Phillips,Stephen Carr, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 DOI: 10.1107/S1744309111029654 |
| October 2011 | An Enlarged, Adaptable Active Site in CYP164 Family P450 Enzymes, the Sole P450 in Mycobacterium leprae Journal Paper, Christopher Agnew,Andrew Warrilow,Nick Burton,David Lamb,Steven Kelly,Leo Brady, Antimicrobial Agents and Chemotherapy 56 (1) DOI: 10.1128/​AAC.05227-11 |
| October 2011 | Structural variability of the Ubiquitin Specific Protease DUSP-UBL double domains Journal Paper, Paul Elliott,Han Liu,Martyna W. Pastok,Guenter Grossmann,Daniel J. Rigden,Michael J. Clague,Sylvie Urbé,Igor L. Barsukov, FEBS Letters DOI: 10.1016/j.febslet.2011.09.040 |
| October 2011 | Assembly of the preactivation complex for urease maturation in Helicobacter pylori: Crystal Structure of the UreF/UreH complex Journal Paper, Yu Hang Fong,H. C. Wong,C. P. Chuck,Yu Wai Chen,H. Sun,K.-B. Wong, Journal of Biological Chemistry DOI: 10.1074/jbc.M111.296830 |
| October 2011 | Crystal structure of reduced and of oxidized peroxiredoxin IV reveals a stable oxidized decamer and a non disulfide-bonded intermediate in the catalytic cycle Journal Paper, Zhenbo Cao,T. J. Tavender,Aleksander Roszak,Richard Cogdell,N. J. Bulleid, Journal of Biological Chemistry DOI: 10.1074/jbc.M111.298810 |
| September 2011 | Novel Inhibitors of NRH:Quinone Oxidoreductase 2 (NQO2): Crystal Structures, Biochemical Activity, and Intracellular Effects of Imidazoacridin-6-ones Journal Paper, Mark S. Dunstan,John Barnes,Matthew Humphries,Roger C. Whitehead,Richard A. Bryce,David Leys,Ian J. Stratford,Karen A. Nolan, Journal of Medicinal Chemistry DOI: 10.1021/jm200416e |
| September 2011 | Altering the stability of the Cdc8 overlap region modulates the ability of this tropomyosin to bind co-operatively to actin and regulate myosin Journal Paper, Daniel A. East,Duncan Sousa,Stephen Martin,Thomas Edwards,William Lehman,Daniel P. Mulvihill, Biochemical Journal 438 DOI: 10.1042/BJ20101316 |
| September 2011 | The three-dimensional structure of mannosyl-3-phosphoglycerate phosphatase from <i>Thermus thermophilus</i> HB27: a new member of the Haloalkanoic Acid Dehalogenase Superfamily Journal Paper, Susana Goncalves,Ana Esteves,Helena Santos,Nuno Borges,Pedro Matias, Biochemistry DOI: 10.1021/bi201171h |
| September 2011 | Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins Journal Paper, Svetlana Antonyuk,Neil Rustage,C. A. Petersen,J. L. Arnst,Derren Heyes,R. Sharma,Neil Berry, Scrutton,Robert Eady,C. R. Andrew,Samar Hasnain, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1109051108 |
| September 2011 | Structure of a Streptomyces maltosyltransferase GlgE: a homologue of a genetically validated anti-tuberculosis target Journal Paper, K. Syson,C. E. M. Stevenson,M. Rejzek,S. A. Fairhurst,A. Nair,C. J. Bruton,R. A. Field,K. F. Chater,D. M. Lawson,S. Bornemann, Journal of Biological Chemistry DOI: 10.1074/jbc.M111.279315 |
| September 2011 | Co-Crystal Structures of Inhibitors with MRCKβ, a Key Regulator of Tumor Cell Invasion Journal Paper, Timo Heikkila,Edward Wheatley,Diane Crighton,Ewald Schroder,Alexandra Boakes,Sarah J. Kaye,Mokdad Mezna,Leon Pang,Mathew Rushbrooke,Andrew Turnbull,Michael F. Olson,Joseph Alan Bauer, PLoS ONE 6 DOI: 10.1371/journal.pone.0024825 |
| September 2011 | Structure and Activity of Paenibacillus polymyxa Xyloglucanase from Glycoside Hydrolase Family 44 Journal Paper, A. Ariza,J. M. Eklof,O. Spadiut,W. A. Offen,S. M. Roberts,W. Besenmatter,E. P. Friis,M. Skjot,K. S. Wilson,H. Brumer,G. Davies, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M111.262345 |
| September 2011 | A widespread family of bacterial cell wall assembly proteins Journal Paper, Yoshikazu Kawai,Jon Marles-Wright,Robert M Cleverley,Robyn Emmins,Shu Ishikawa,Masayoshi Kuwano,Nadja Heinz,Nhat Khai Bui,Christopher N Hoyland,Naotake Ogasawara,Rick Lewis,Waldemar Vollmer,Richard A Daniel,Jeff Errington, The EMBO Journal DOI: 10.1038/emboj.2011.358 |
| September 2011 | Altering the stability of the Cdc8 overlap region modulates the ability of this tropomyosin to bind co-operatively to actin and regulate myosin Journal Paper, Daniel A. East,Duncan Sousa,Stephen Martin,Thomas Edwards,William Lehman,Daniel P. Mulvihill, Biochemical Journal 438 DOI: 10.1042/BJ20101316 |
| September 2011 | Unusual, Dual Endo- and Exonuclease Activity in the Degradosome Explained by Crystal Structure Analysis of RNase J1 Journal Paper, Joseph A Newman,Lorraine Hewitt,Cecilia Rodriguez,Alexandra Solovyova,Colin R. Harwood,Rick Lewis, Structure 19 DOI: 10.1016/j.str.2011.06.017 |
| September 2011 | Structural basis for cell surface patterning through NetrinGNGL interactions Journal Paper, Elena Seiradake,Charlotte H Coles,Pavel V Perestenko,Karl Harlos,Robert Andrew Jeffrey McIlhinney,Alexandru Aricescu,Yvonne Jones, The EMBO Journal DOI: 10.1038/emboj.2011.346 |
| September 2011 | The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase Journal Paper, Dea Slade,Mark S. Dunstan,Eva Barkauskaite,Ria Weston,Pierre Lafite,Neil Dixon,Marijan Ahel,David Leys,Ivan Ahel, Nature 477 DOI: 10.1038/nature10404 |
| September 2011 | Non-equivalent role of inter- and intra-molecular hydrogen bonds in the insulin dimer interface Journal Paper, Antolikova, Zakova,Johan Turkenburg,C. J. Watson,I. Hanclova,M. Sanda,A. Cooper,T. Kraus, Brzozowski,J. Jiracek, Journal of Biological Chemistry DOI: 10.1074/jbc.M111.265249 |
| September 2011 | Molecular basis of α1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer Journal Paper, Massayuki Yamasaki,Timothy Sendall,Mary C Pearce,James C Whisstock,James Huntingdon, EMBO reports DOI: 10.1038/embor.2011.171 |
| August 2011 | Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding Journal Paper, Christopher Agnew,Elena Borodina,Nathan Zaccai,Rebecca Conners,Nick Burton,J. A. Vicary,David Cole,Massimo Antognozzi,Mumtaz Virji,R. L. Brady, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1106341108 |
| August 2011 | The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding Journal Paper, Tung Le,M. A. Schumacher,David Lawson,R. G. Brennan,Mark Buttner, Nucleic Acids Research DOI: 10.1093/nar/gkr640 |
| August 2011 | Structure of the USP15 N-Terminal Domains: A Beta-Hairpin Mediates Close Association between the DUSP and UBL Domains Journal Paper, Stephen Harper,Tabot M. D. Besong,Jonas Emsley,David J. Scott,Ingrid Dreveny, Biochemistry 50 DOI: 10.1021/bi200726e |
| August 2011 | Structures of Phytophthora RXLR effector proteins: a conserved but adaptable fold underpins functional diversity Journal Paper, Laurence Boutemy,S. R. F. King,J. Win,Richard Hughes,T. A. Clarke,T. M. A. Blumenschein,S. Kamoun,Mark Banfield, Journal of Biological Chemistry DOI: 10.1074/jbc.M111.262303 |
| July 2011 | Crystallographic determination of the disease-associated T1184R variant of complement regulator factor H Journal Paper, Hugh Morgan,Jingzi Jiang,Andrew P. Herbert,David Kavanagh,Duan Uhrin,Paul N. Barlow,Jonathan Hannan, Acta Crystallographica Section D Biological Crystallography 67 DOI: 10.1107/S0907444911015423 PMID: 21697597 |
| July 2011 | Crystal Structure of Serratia fonticola Sfh-I: Activation of the Nucleophile in Mono-Zinc Metallo-beta-Lactamases Journal Paper, Fatima Fonseca,Elizabeth Bromley,Maria José Saavedra,António Correia,Jim Spencer, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.06.043 |
| July 2011 | The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site Journal Paper, Hugh Morgan,Iain McNae,Matthew Nowicki,W. Zhong,P. A. M. Michels,D. S. Auld,L. A. Fothergill-Gilmore,Malcolm Walkinshaw, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M110.212613 PMID: PMC3173065 |
| July 2011 | Crystallographic determination of the disease-associated T1184R variant of complement regulator factor H Journal Paper, Hugh Morgan,Jingzi Jiang,Andrew P. Herbert,David Kavanagh,Duan Uhrin,Paul N. Barlow,Jonathan Hannan, Acta Crystallographica Section D Biological Crystallography 67 DOI: 10.1107/S0907444911015423 PMID: 21697597 |
| July 2011 | Structure of human caspase-6 in complex with Z-VAD-FMK: New peptide binding mode observed for the non-canonical caspase conformation Journal Paper, Ilka Müller,Marieke B. A.C. Lamers,Alison J. Ritchie,Celia Dominguez,Ignacio Munoz,Alex Kiselyov, Bioorganic & Medicinal Chemistry Letters DOI: 10.1016/j.bmcl.2011.07.041 |
| July 2011 | Use of the α-mannosidase I inhibitor kifunensine allows the crystallization of apo CTLA-4 homodimer produced in long-term cultures of Chinese hamster ovary cells Journal Paper, Chao Yu,Max Crispin,Andreas Sonnen,David J. Harvey,Veronica T. Chang,Edward J. Evans,Christopher N. Scanlan,Dave Stuart,Robert J. C. Gilbert,Simon J. Davis, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 DOI: 10.1107/S1744309111017672 |
| July 2011 | The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site Journal Paper, Hugh Morgan,Iain McNae,Matthew Nowicki,W. Zhong,P. A. M. Michels,D. S. Auld,L. A. Fothergill-Gilmore,Malcolm Walkinshaw, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M110.212613 PMID: PMC3173065 |
| July 2011 | The light intensity at which cells are grown controls the type of peripheral light-harvesting complexes that are assembled in a purple photosynthetic bacterium Journal Paper, Tatas Brotosudarmo,Aaron Collins,Andrew Gall,Aleksander Roszak,Alastair Gardiner,Robert Blankenship,Richard Cogdell, Biochemical Journal DOI: 10.1042/BJ20110575 |
| July 2011 | Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90 Journal Paper, Stefan Millson,C.-S. Chua,Mark Roe,S. Polier,S. Solovieva,L. H. Pearl,T.-S. Sim,C. Prodromou,P. W. Piper, The FASEB Journal DOI: 10.1096/fj.11-188821 PMID: 21778327 |
| July 2011 | Structures of the rat complement regulator CrrY Journal Paper, Pietro Roversi,Steven Johnson,Joseph J. E. Caesar,Florence McLean,Kirstin J. Leath,Stefanos A. Tsiftsoglou,B. Paul Morgan,Claire L. Harris,Robert B Sim,Susan Lea, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 DOI: 10.1107/S1744309111016551 |
| July 2011 | Structural and Functional Analyses of the Second-generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572) Journal Paper, Stephen Hare,S. J. Smith,M. Metifiot,A. Jaxa-Chamiec,Y. Pommier,S. H. Hughes,Peter Cherepanov, Molecular Pharmacology DOI: 10.1124/mol.111.073189 |
| July 2011 | Expression, purification, crystallization and preliminary crystallographic analysis of a putative Journal Paper, Jonathan M. Kirby,Nethaji Thiyagarajan,April Roberts,Clifford Shone,Ravi Acharya, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 DOI: 10.1107/S1744309111016770 |
| June 2011 | Mapping Lipid and Detergent Molecules at the Surface of Membrane Proteins Conference Paper, Richard Cogdell, null PMID: 21599648 |
| June 2011 | The Virulence Factor PEB4 (Cj0596) and the Periplasmic Protein Cj1289 Are Two Structurally Related SurA-like Chaperones in the Human Pathogen Campylobacter jejuni Journal Paper, A. Kale,C. Phansopa,C. Suwannachart,C. J. Craven,J. B. Rafferty,D. J. Kelly, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M111.220442 |
| June 2011 | Protein crystallization facilitated by molecularly imprinted polymers Journal Paper, Emmanuel Saridakis,S. Khurshid,L. Govada,Q. Phan,D. Hawkins,G. V. Crichlow,E. Lolis,S. M. Reddy,N. E. Chayen, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1016539108 |
| June 2011 | X-ray Crystallographic Structure of the Murine Norovirus protease at 1.66 Å Resolution and Functional Studies of the β-ribbon Thesis, Gabriela Baeza, null |
| June 2011 | Simultaneous X-ray diffraction from multiple single crystals of macromolecules Journal Paper, Karthik Paithankar,Henning O. Sørensen,Jonathan P. Wright,Søren Schmidt,Henning F. Poulsen,Elspeth F. Garman, Acta Crystallographica Section D Biological Crystallography 67 DOI: 10.1107/S0907444911015617 |
| June 2011 | The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor Journal Paper, Li Zhang,Louise Fairall,Benjamin Goult,Anna Calkin,Cynthia Hong,Chris Millard,Peter Tontonoz,John Schwabe, Genes & Development 25 DOI: 10.1101/gad.2056211 |
| May 2011 | Bilirubin oxidase from Myrothecium verrucaria: X-ray determination of the complete crystal structure and a rational surface modification for enhanced electrocatalytic O2 reduction Journal Paper, James Cracknell,Thomas McNamara,Ed Lowe,Christopher Blanford, Dalton Transactions Advance Article DOI: 10.1039/C0DT01403F |
| May 2011 | The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains Journal Paper, Daniel Ryan,Ramasubramanian Sundaramoorthy,David Martin,Vijender Singh,Tom Owen-Hughes, The EMBO Journal DOI: 10.1038/emboj.2011.166 |
| May 2011 | The Crystal Structure of the Leishmania major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, dUMP, and Deoxyuridine Journal Paper, G. R. Hemsworth,O. V. Moroz,M. J. Fogg,B. Scott,C. Bosch-Navarrete,D. Gonzalez-Pacanowska,K. S. Wilson, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M111.224873 |
| May 2011 | Assessment of radiation damage behaviour in a large collection of empirically optimized datasets highlights the importance of unmeasured complicating effects Journal Paper, Tobias Krojer,Frank von Delft, Journal of Synchrotron Radiation 18 (3) DOI: 10.1107/S0909049511008235 |
| April 2011 | Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI Journal Paper, Mary D Holdom,Anna M Davies,Joanne E Nettleship,Sarah C Bagby,Balvinder Dhaliwal,Enrico Girardi,James Hunt,Hannah J Gould,Andrew J Beavil,James M McDonnell,Ray J Owens,Brian J Sutton, Nature Structural & Molecular Biology 18 DOI: 10.1038/nsmb.2044 PMID: 21516097 |
| April 2011 | Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis Journal Paper, Roisin McMahon,Lone Friis,Christian Siebold,Lars Fugger,Yvonne Jones, Acta Crystallographica Section D Biological Crystallography 67 DOI: 10.1107/S0907444911007888 |
| April 2011 | Structural analysis of a novel class of R-M controller proteins: C.Csp231I from Citrobacter sp. RFL231 Journal Paper, John McGeehan, Streeter, Thresh,J Taylor,Mikhail Shevtsov,Geoff Kneale, Journal of Molecular Biology DOI: Structural analysis of a novel class of R-M controller proteins: C.Csp231I from Citrobacter sp. RFL231 |
| April 2011 | A crystal structure of the complex between human complement receptor 2 and its ligand C3d Journal Paper, Jean van den Elsen,David Isenman, Science 332 DOI: 10.1126/science.1201954 |
| April 2011 | From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo-Like Kinase 1 Journal Paper, Pawel Sledz,Christopher Stubbs,Steffen Lang,Yong-Qing Yang,Grahame McKenzie,Ashok Venkitaraman,Marko Hyvonen,Chris Abell, Angewandte Chemie 123 (17) DOI: 10.1002/ange.201008019 |
| April 2011 | Structural insights into the retroviral DNA integration apparatus Journal Paper, Peter Cherepanov,Goedele Maertens,Stephen Hare, Current Opinion in Structural Biology 21 DOI: 10.1016/j.sbi.2010.12.005 |
| April 2011 | The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases Journal Paper, Rasheduzzaman Chowdhury, Yeoh, Tian,Lars Hillringhaus,Eleanor Bagg,Nathan Rose, Leung,Xuan Li, Woon,Ming Yang,Michael McDonough,Oliver King,Ian Clifton,Robert Klose,Timothy Claridge,Peter Ratcliffe, Schofield,Akane Kawamura, EMBO reports 12 DOI: 10.1038/embor.2011.43 |
| April 2011 | Proteoglycan-Specific Molecular Switch for RPTP Clustering and Neuronal Extension Journal Paper, C. H. Coles,Y. Shen,A. P. Tenney,Christian Siebold,G. C. Sutton,W. Lu,J. T. Gallagher,E. Y. Jones,J. G. Flanagan,Alexandru Aricescu, Science 332 DOI: 10.1126/science.1200840 |
| April 2011 | Expression, crystallization and preliminary X-ray data analysis of NT-ALS9, a fungal adhesin from Candida albicans Journal Paper, Paula Salgado,Robert Yan,Rowantree Niall,Ernesto Cota-Segura, Acta Crystallographica Section F Structural Biology and Crystallization Communications DOI: 10.1107/S1744309111003460 |
| March 2011 | Understanding small-molecule binding to MDM2: Insights into structural effects of isoindolinone inhibitors from NMR spectroscopy Journal Paper, Christiane Riedinger,Martin Noble, Wright, Mulks, Hardcastle,Jane Endicott, McDonnell , Chemical Biology and Drug Design DOI: 10.1111/j.1747-0285.2011.01091.x |
| March 2011 | Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure−Activity Relationship Journal Paper, Richard Bayliss,C Mas-Droux,Rob van Montfort, J Med Chem. 54 PMID: 21366329 |
| March 2011 | Helix-mediated protein-protein interactions as targets for intervention using foldamers Journal Paper, Thomas Edwards,Andrew Wilson, Amino Acids DOI: 10.1007/s00726-011-0880-8 |
| March 2011 | Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers. Journal Paper, Maxim Rossmann,Madhav Sukumaran,A Penn, Veprintsev,Madan Babu,Ingo Greger, The EMBO Journal 30 DOI: 10.1038/emboj.2011.16 |
| March 2011 | Dynamics and allosteric potential of the AMPA receptor N-terminal domain Journal Paper, Madhav Sukumaran,Maxim Rossmann,I shrivastava,A Dutta,I Bahar,Ingo Greger, The EMBO Journal 30 DOI: 10.1038/emboj.2011.17 |
| March 2011 | Crystallization and preliminary X-ray analysis of the bacillaene synthase trans-acting acyltransferase PksC Journal Paper, Fiona Cuskin,Alexandra Solovyova,Rick Lewis,Paul Race, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(4) DOI: doi:10.1107/S1744309111003484 |
| March 2011 | Structure of mammalian AMPK and its regulation by ADP Journal Paper, Bing Xiao,Matthew J. Sanders,Elizabeth Underwood,Richard Heath,Faith V. Mayer,David Carmena,Chun Jing,Philip A. Walker,John F. Eccleston,Lesley F. Haire,Peter Saiu,Steven A. Howell,Rein Aasland,Stephen R. Martin,David Carling,Steven J. Gamblin, Nature 472 DOI: 10.1038/nature09932 PMID: 21399626 |
| February 2011 | Structure of PduT, a trimeric bacterial microcompartment protein with a 4Fe-4S cluster-binding site Journal Paper, Allan Pang,M Warren,Richard Pickersgill, Biological Crystallography 67 (2) DOI: 10.1107/S0907444910050201 |
| February 2011 | Novel mechanism of inhibition of human Angiotensin-I converting enzyme (ACE) by a highly specific phosphinic tripeptide Journal Paper, Akif Mohd,Sylva Schwager,Colin Anthony,Bertrand Czarny,Fabrice Beau,Edward Sturrock,Ravi Acharya, Biochemical Journal DOI: 10.1042/BJ20102123 |
| February 2011 | Structural basis for the subunit assembly of the anaphase-promoting complex Journal Paper, Anne Schreiber,Florian Stengel,Ziguo Zhang,Radoslav I. Enchev,Eric H. Kong,Edward P. Morris,Carole Robinson,Paula C. A. da Fonseca,David Barford, Nature 470 DOI: 10.1038/nature09756 PMID: 21307936 |
| February 2011 | Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response Journal Paper, Maruf M U Ali,Tina Bagratuni,Emma L Davenport,Piotr R Nowak,M Cris Silva-Santisteban,Anthea Hardcastle,Craig McAndrews,Martin G Rowlands,Gareth J Morgan,Wynne Aherne,Ian Collins,Faith E Davies,Laurence H Pearl, The EMBO Journal 30 DOI: 10.1038/emboj.2011.18 PMID: 21317875 |
| February 2011 | Structural basis for engagement by complement factor H of C3b on a self surface Journal Paper, Hugh P Morgan,Christoph Q Schmidt,Mara Guariento,Bärbel S Blaum,Dominic Gillespie,Andrew P Herbert,David Kavanagh,Haydyn D T Mertens,Dmitri I Svergun,Conny M Johansson,Duan Uhrín,Paul N Barlow,Jonathan P Hannan, Nature Structural & Molecular Biology 18 DOI: 10.1038/nsmb.2018 |
| February 2011 | Structures of the TetR-like simocyclinone efflux pump repressor, SimR, and the mechanism of ligand-mediated derepression Journal Paper, Tung Le,Clare Stevenson,Hans-Peter Fiedler,Anthony Maxwell,David Lawson,Mark Buttner, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.02.035 |
| February 2011 | Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains Journal Paper, Ming Yang,Rasheduzzaman Chowdhury,Wei Ge,Refaat Hamed,Michael McDonough,Timothy Claridge,Benedikt Kessler,Matthew Cockman,Peter Ratcliffe,Christopher Schofield, FEBS Letters 278 DOI: 10.1111/j.1742-4658.2011.08022.x |
| February 2011 | Structural Basis of Telomeric RNA Quadruplex−Acridine Ligand Recognition Journal Paper, Gavin Collie,Silvia Sparapani ,Gary Parkinson,Stephen Neidle, Journal of the American Chemical Society DOI: 10.1021/ja109767y |
| February 2011 | Structural basis for engagement by complement factor H of C3b on a self surface Journal Paper, Hugh P Morgan,Christoph Q Schmidt,Mara Guariento,Bärbel S Blaum,Dominic Gillespie,Andrew P Herbert,David Kavanagh,Haydyn D T Mertens,Dmitri I Svergun,Conny M Johansson,Duan Uhrín,Paul N Barlow,Jonathan P Hannan, Nature Structural & Molecular Biology 18 DOI: 10.1038/nsmb.2018 |
| January 2011 | Crystallization and initial crystallographic analysis of AafA: the major adhesive subunit of the enteroaggregative Journal Paper, Yi Yang,James A. Garnett,Stephen Matthews, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 DOI: 10.1107/S1744309111001412 |
| January 2011 | A processed noncoding RNA regulates an altruistic bacterial antiviral system Journal Paper, Tim Blower,Xue-Yuan Pei,Francesca Short,P Fineran,David Humphreys,Ben Luisi,George Salmond, Nature Structural & Molecular Biology 18 DOI: 10.1038/nsmb.1981 |
| January 2011 | Extending the usability of the phasing power of diselenide bonds: SeCys SAD phasing of CsgC using a non-auxotrophic strain. Journal Paper, Paula Salgado,Jon Taylor,Ernesto Cota-Segura,Steve Matthews, Acta Crystallogr D Biol Crystallogr 67 DOI: 10.1107/S0907444910042022 |
| January 2011 | Structural and functional characterization of Pseudomonas aeruginosa CupB chaperones. Journal Paper, Xun Cai,Rui Wang,Alain Filloux,Gabriel Waksman,Goyu Meng, PLoS One DOI: 10.1371/journal.pone.0016583 |
| January 2011 | Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis Journal Paper, Wen-Jun Gui,Shi-Qiang Lin,Yuan-Yuan Chen,Xian-En Zhang,Li-Jun Bi,Tao Jiang, Biochemical and Biophysical Research Communications DOI: 10.1016/j.bbrc.2011.01.027 |
| January 2011 | Nature of the Ferryl Heme in Compounds I and II Journal Paper, Andrea Gumiero,C Metcalfe,Arwen Pearson,Emma Raven,Peter Moody, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M110.183483 |
| January 2011 | Dissecting the mechanism of oxygen trafficking in a metalloenzyme Journal Paper, Mark Smith,Peter Knowles,Michael McPherson,Arwen Pearson, Faraday Discussions 148 DOI: 10.1039/c005054g |
| January 2011 | Phosphotyrosine recognition by the Raf Kinase Inhibitor Protein Journal Paper, Philip Simister,Nick Burton,Leo Brady, Forum on Immunopathological Diseases and Therapeutics 2(1) DOI: 10.1615/ForumImmunDisTher.v2.i1.70 |
| January 2011 | Structure of recombinant Leishmania donovani pteridine reductase reveals a disordered active site Journal Paper, Keri Barrack,L Tulloch,L Burke,Paul Fyfe,William Hunter, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 (1) DOI: 10.1107/S174430911004724X |
| January 2011 | Structure and mechanism of the chalcogen detoxifying protein TehB from Escherichia coli Journal Paper, Hassan Choudhury,Alex Cameron,So Iwata,Konstantinos Beis, Biochemical Journal DOI: 10.1042/BJ20102014 |
| January 2011 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2 Journal Paper, John J. Caldwell,Emma J. Welsh,Cornelis Matijssen,Victoria E. Anderson,Laurent Antoni,Kathy Boxall,Frederique Urban,Angela Hayes,Florence I. Raynaud,Laurent J. M. Rigoreau,Tony Raynham,G. Wynne Aherne,Laurence H. Pearl,Antony W. Oliver,Michelle D. Garrett,Ian Collins, Journal of Medicinal Chemistry 54 DOI: 10.1021/jm101150b PMID: 21186793 |
| January 2011 | Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery Journal Paper, Jasmeen Oberoi,Louise Fairall,Peter J Watson,Ji-Chun Yang,Zsolt Czimmerer,Thorsten Kampmann,Ben Goult,Jacquie Greenwood,John Gooch,Bettina Kallenburger,Laszlo Nagy,David Neuhaus,John Schwabe, Nature Structural & Molecular Biology 18 DOI: 10.1038/nsmb.1983 |
| January 2011 | Structure and mechanism of the chalcogen detoxifying protein TehB from Escherichia coli Journal Paper, Hassan Choudhury,Alex Cameron,So Iwata,Konstantinos Beis, Biochemical Journal DOI: 10.1042/BJ20102014 |
| January 2011 | The structure of human complement factor I Conference Paper, Pietro Roversi,Steven Johnson, null |
| January 2011 | Copper-Binding Properties and Structures of Methanobactins from Methylosinus trichosporium OB3b Journal Paper, Abdelnasser El Ghazouani,Arnaud Basle,Susan Firbank,Charles Knapp,Joe Gray,David Graham,Christopher Dennisson, Inorganic Chemistry 50(4) DOI: 10.1021/ic101965j |
| January 2011 | Importance of single molecular determinants in the fidelity of expanded genetic codes Journal Paper, A. K. Antonczak,Z. Simova,I. T. Yonemoto,M. Bochtler,A. Piasecka,H. Czapinska,A. Brancale,E. M. Tippmann, Proceedings of the National Academy of Sciences 108 DOI: 10.1073/pnas.1012276108 |
| December 2010 | Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding Journal Paper, Joel Kaar,Nicolas Basse,Andreas Christian Joerger,Elaine Stephens,Trevor Rutherford,Alan Fersht, PROTEIN SCIENCE 19 DOI: 10.1002/pro.507 |
| December 2010 | Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen Journal Paper, M Driscoll,Kirsty J. McLean,Colin Levy,Nathalia Mast,Irina A Pikuleva,David Leys,Pierre Lafite,Stephen Rigby,Andrew Munro, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M110.164293 PMID: 20889498 |
| December 2010 | Cloning, purification and preliminary crystallographic analysis of cobalamin methyltransferases from Rhodobacter capsulatus Journal Paper, Arefeh Seyedarabi,M-T Hutchison,T To,E Deery,A Brindley,M Warren,Richard Pickersgill, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 (12) DOI: 10.1107/S1744309110042910 |
| December 2010 | The crystal structure of the ubiquitin-like (UbL) domain of human homologue A of Rad23 (hHR23A) protein Journal Paper, Y. W. Chen,T. Tajima,S. Agrawal, Protein Engineering Design and Selection 24 DOI: 10.1093/protein/gzq084 |
| December 2010 | Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis Journal Paper, Mads Gabrielsen,Caroline Zetterström,Dai Wang,Katherine Beckham,Mikael Elofsson, Isaacs,Andrew Roe, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 (10) DOI: 10.1107/S1744309110039679 |
| December 2010 | Structural basis of poly(ADP-ribose) recognition by the multizinc binding domain of checkpoint with forkhead-associated and RING Domains (CHFR) Journal Paper, Richard Bayliss,Jasmeen Oberoi,M Richards,N Brown, Journal of Biological Chemistry 285 PMID: 20880844 |
| December 2010 | Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosis Journal Paper, Chandrakala Basavannacharya,Paul Moody,Tulika Munshi,Nora Cronin,Nicholas Keep,Sanjib Bhakta, Protein and Cell 1 (11) DOI: 10.1007/s13238-010-0132-9 |
| December 2010 | The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease Journal Paper, Martin Reijns,Doryen Bubeck,Lucien Gibson,Stephen Graham,George Baillie,Yvonne Jones,Andrew Jackson, Journal of Biological Chemistry DOI: 10.1074/jbc.M110.177394 |
| November 2010 | Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators. Journal Paper, Duo Lu,Sandy Fillet, Meng,Yilmaz Alguel,Patrick Kloppsteck, Bergeron, Krell, Gallegos, Ramos,Xiaodong Zhang, Genes Dev 24(22) DOI: 10.1101/gad.603510 |
| November 2010 | Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization. Journal Paper, Richard Bayliss,C Mas-Droux,Rob van Montfort, J Med Chem. 53 PMID: 20936789 |
| November 2010 | A structural basis for Staphylococcal complement subversion: X-ray structure of the complement-binding domain of Staphylococcus aureus protein Sbi in complex with ligand C3d Journal Paper, Elizabeth Clark,Susan Crennell,Abhisehk Upadhyay,Alexey Zozulya,Julia Mackay,Dmitri Svergun,Stefan Bagby,Jean van den Elsen, Molecular Immunology DOI: 10.1016/j.molimm.2010.09.017 |
| November 2010 | The mechanism of retroviral integration from X-ray structures of its key intermediates. Journal Paper, Goedele Maertens,Stephen Hare,Peter Cherepanov, Nature 468 DOI: 10.1038/nature09517 |
| November 2010 | Trapping of palindromic ligands within native transthyretin prevents amyloid formation Journal Paper, Simon Kolstoe,Palma Mangione,Vittorio Bellotti,Graham Taylor,Glenys Tennent,Stéphanie Deroo Deroo,Angus Morrison,Alexander Cobb,Anthony Coyne,Margaret McCammon,Timothy Warner,Jane Mitchell,Raj Gill,Martin Smith,Steven Ley,Carol Robinson,Stephen Wood,Mark Pepys, Proceedings of the National Academy of Sciences 107(47) DOI: 10.1073/pnas.1008255107 |
| November 2010 | Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors Journal Paper, Oliver King,Xuan Shirley LI,Masaaki Sakurai,Akane Kawamura,Nathan Rose,Stanley Ng,Amy Quinn,Ganesha Rai,Bryan Mott,Paul Beswick,Robert Klose,Udo Oppermann,Ajit Jadhav,Tom Heightman,David Maloney,Christopher Schofield,Anton Simeonov, PLoS One DOI: 10.1371/journal.pone.0015535 |
| October 2010 | Filament structure of bacterial tubulin homologue TubZ Journal Paper, Christopher Aylett,Qing Wang,Kate Michie,Linda Amos,Jan Lowe, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1010176107 |
| October 2010 | Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations Journal Paper, H. L. Schubert,Q. Zhai,V. Sandrin,D. M. Eckert,M. Garcia-Maya,L. Saul,W. I. Sundquist,Roberto Steiner,C. P. Hill, Proceedings of the National Academy of Sciences 107 DOI: 10.1073/pnas.1008206107 |
| October 2010 | A redox switch in angiotensinogen modulates angiotensin release Journal Paper, Aiwu Zhou,Robin Carrell,Michael Murphy,Zhenquan Wei,Yahui Yan,Peter Stanley,Penelope Stein,Fiona Broughton Pipkin,Randy Read, Nature DOI: 10.1038/nature09505 |
| October 2010 | Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance Journal Paper, Stephen Hare,Ann Vos,Reginald Clayton,Jan Thuring,Maxwell Cummings,Peter Cherepanov, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1010246107 |
| September 2010 | Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface Journal Paper, David C. Goldstone,Melvyn W. Yap,Laura E. Robertson,Lesley F. Haire,William R. Taylor,Aris Katzourakis,Jonathan P. Stoye,Ian A. Taylor, Cell Host & Microbe 8 DOI: 10.1016/j.chom.2010.08.006 PMID: 20833376 |
| September 2010 | A disulfide driven domain swap switches off the activity of Shigella IpaH9.8 E3 ligase Journal Paper, Arefeh Seyedarabi,James Sullivan,Chihiro Sasakawa,Richard Pickersgill, FEBS Letters DOI: 10.1016/j.febslet.2010.09.006 |
| September 2010 | Comparative Structural Analysis of Human DEAD-Box RNA Helicases Journal Paper, Schutz,Tobias Karlberg,Susanne van den Berg,Ruairi Collins, Lehtio,Martin Högbom,Lovisa Holmberg-Schiavone,Wolfram Tempel,Hee-Won Park, Hammarstrom,Martin Moche,Ann-Gerd Thorsell,Herwig Schuler, PLoS One 5(9) PMID: 20941364 |
| September 2010 | The structure of the FnIII Tandem A77-A78 points to a periodically conserved architecture in the myosin-binding region of titin Journal Paper, Olga Mayans, Journal of Molecular Biology 401 PMID: 20542041 |
| September 2010 | The structural basis for catalysis and substrate specificity of a rhomboid protease Journal Paper, Kutti Vinothkumar,Kvido Strisovsky, Andreeva,Yonka Christova,Steven Verhelst, Freeman, The EMBO Journal DOI: 10.1038/emboj.2010.243 |
| September 2010 | Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'. Journal Paper, Klaus Fütterer,Sarah Batt,T Jabeen,Ajay Mishra,N Veerapen,K Krumbach,L Eggeling,G Besra, Journal of Biological Chemistry 285 PMID: 20843801 |
| September 2010 | The structure of the genomic Bacillus subtilis dUTPase: novel features in the Phe-lid Journal Paper, J García-Nafría,Lynn Burchell,M Takezawa,Neil Rzechorzek,Mark Fogg,Keith Wilson, Acta Crystallographica Section D Biological Crystallography 66 (9) DOI: 10.1107/S0907444910026272 |
| September 2010 | Structural Insights into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution Journal Paper, Ivan Campeotto,Amanda Bolt,Thomas Harman ,Caitriona Dennis,Chi Hung Trinh,Simon Phillips, Nelson,Arwen Pearson,Alan Berry, Journal of Molecular Biology DOI: 10.1016/j.jmb.2010.08.008 |
| August 2010 | Crystal structure of MexZ, a key repressor responsible for antibiotic resistance in Pseudomonas aeruginosa Journal Paper, Yilmaz Alguel,Duo Lu,Nick Quade, Sauter,Xiaodong Zhang, Journal of Structural Biology 172(3) PMID: 20691272 |
| August 2010 | Structure of Staphylococcus aureus adenylosuccinate lyase (PurB) and assessment of its potential as a target for structure-based inhibitor discovery Journal Paper, Paul Fyfe,Alice Dawson,M-T Hutchison,Scott Cameron,William N. Hunter, Acta Crystallographica Section D Biological Crystallography 66 (8) DOI: 10.1107/S0907444910020081 |
| August 2010 | Structural determination of functional domains in Early B-cell Factor (EBF) family of transcription factors reveals similarities to rel DNA binding proteins and a novel dimerisation motif. Journal Paper, Marina Siponen, Wisniewska, Lehtio, Johansson,Linda Svensson,Grzegorz Raszewski,Lennart Nilsson,Mikael Sigvardsson,Helena Berglund, Journal of Biological Chemistry 285(34) PMID: 20592035 |
| August 2010 | Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6 Journal Paper, Monica Mantri,Tobias Krojer,Eleanor Bagg,Celia Webby,Danica Butler,Grazyna Kochan,Kathryn Kavanagh,Udo Oppermann,Michael McDonough, Schofield, Journal of Molecular Biology 401 (2) DOI: 10.1016/j.jmb.2010.05.054 |
| June 2010 | Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases Journal Paper, Ivan Laponogov,Xiao-Su Pan,Dennis A. Veselkov,Katherine McAuley,L. Mark Fisher,Mark R. Sanderson,Art J. Lustig, PLoS ONE 5 DOI: 10.1371/journal.pone.0011338 |
| June 2010 | Specificity of Polysaccharide Use in Intestinal Bacteroides Species Determines Diet-Induced Microbiota Alterations Journal Paper, Erica Sonnenburg,Hongjun Zheng,Payal Joglekar,Steven Higginbottom,Susan Firbank,David Bolam,Justin Sonnenburg, Cell 141 (7) DOI: 10.1016/j.cell.2010.05.005 |
| June 2010 | Probing the interaction of archaeal DNA polymerases with deaminated bases using X-ray crystallography and non-hydrogen bonding isosteric base analogues Journal Paper, Tom Killilea,Samantak Ghosh,Samuel Tan,Pauline Heslop,Susan Firbank,Eric Kool,Bernard Connolly, Biochemistry 49 (27) DOI: 10.1021/bi100421r |
| May 2010 | High-Resolution Crystal Structures of Drosophila melanogaster Angiotensin-Converting Enzyme in Complex with Novel Inhibitors and Antihypertensive Drugs Journal Paper, Akif Mohd,Dimitris Georgiadis,Aman Mahajan,Vincent Dive,Edward Sturrock,R Elwyn Isaac,Ravi Acharya, Journal of Molecular Biology 400 DOI: doi:10.1016/j.jmb.2010.05.024 |
| May 2010 | Crystallization and preliminary crystallographic analysis of the central domain of Drosophila Dribble, a protein essential for ribosome biogenesis Journal Paper, Tat-Cheung Cheng,Yu Wai Chen,Kam-Bo Wong,H. Y. Edwin Chan, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 DOI: 10.1107/S1744309110011206 |
| May 2010 | Structure of the Rna15 RRM-RNA complex reveals the molecular basis of GU specificity in transcriptional 3'-end processing factors Journal Paper, Christina Pancevac,David Goldstone,Andres Ramos,Ian Taylor, Nucleic Acids Research DOI: 10.1093/nar/gkq002 PMID: 20097654 |
| April 2010 | Structure of the aliphatic sulfonate-binding protein SsuA from Escherichia coli Journal Paper, John Beale,Sang Lee,So Iwata,Konstantinos Beis, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 DOI: 10.1107/S1744309110006226 |
| April 2010 | Structural homology between the C-terminal domain of the PapC usher and its plug. Journal Paper, Bradley Ford,Ana Toste Rego,Timothy Ragan,Jerome Pinkner,Karen Dodson,Paul Driscoll,Scott Hultgren,Gabriel Waksman, Journal of Bacteriology 10.1128/JB.01677-09 |
| April 2010 | With phases: how two wrongs can sometimes make a right Journal Paper, Pietro Roversi,Steven Johnson,Susan Lea, Acta Crystallographica Section D Biological Crystallography 66 DOI: 10.1107/S0907444909048112 PMID: 20382995 |
| April 2010 | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3 Journal Paper, Hazel Girwan,Colin Levy,P Williams,K Fisher,Myles Cheesman,Stephen Rigby,David Leys,Andrew Munro, Biochemical Journal 427 PMID: 20180779 |
| April 2010 | Co-factor-independent oxidases and oxygenases Journal Paper, Susan Fetzner,Roberto Steiner, Applied Microbiology and Biotechnology 3 PMID: 20157809 |
| April 2010 | Targeting transthyretin X-ray crystallography and rational drug design Journal Paper, Simon Kolstoe,Angus Morrison,Alexander Cobb,Anthony Coyne,G Gill, Smith, Ley, Wood, Pepys, Amyloid 17 (s1) DOI: 10.3109/13506121003737419 |
| April 2010 | Domain cross-talk during effector binding to the multidrug binding TTGR regulator Journal Paper, Craig Daniels, Daddaoua,Duo Lu,Xiaodong Zhang, Ramos, Journal of Biological Chemistry 285(28) DOI: 10.1074/jbc.M110.113282 |
| March 2010 | Structure and oligomerization of the PilC type IV pilus biogenesis protein from Thermus thermophilus Journal Paper, Vijaykumar Karuppiah, Hassan,Muhammad Saleem,Jeremy Derrick, Proteins: Structure, Function, Bioinformatics 78 (9) DOI: 10.1002/prot.22720 |
| March 2010 | Assembly of a 20-nm Protein Cage by Escherichia coli 2-Hydroxypentadienoic Acid Hydratase Journal Paper, Martin Montgomery,Alun Coker,Alexander I Itaylor,S Wood, Journal of Molecular Biology 396 (5) DOI: 10.1016/j.jmb.2009.12.056 |
| March 2010 | An analysis of substrate binding interactions in the heme peroxidase enzymes Journal Paper, Andrea Gumiero, Murphy,C Metcalfe,Peter Moody,Emma Raven, Arch Biochem Biophys in press DOI: doi:10.1016/j.abb.2010.02.015 PMID: 20206594 |
| March 2010 | The crystal structure of unmodified tRNAPhe from Escherichia coli Journal Paper, Robert Byrne,Andrey Konevega,Maria Rodnina,Fred Antson, Nucleic Acids Research 38 (12) DOI: 10.1093/nar/gkq133 |
| February 2010 | Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites Journal Paper, Alexander I. Taylor,Brian J. Sutton,Rosaleen A. Calvert, Developmental & Comparative Immunology 34 DOI: 10.1016/j.dci.2009.08.012 PMID: 19733585 |
| February 2010 | Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex Journal Paper, S. Pernigo,A. Fukuzawa,M. Bertz,M. Holt,M. Rief,R. A. Steiner,M. Gautel, Proceedings of the National Academy of Sciences 107 DOI: 10.1073/pnas.0913736107 |
| February 2010 | The structure of the catalytic subunit FANCL of the Fanconi anemia core complex Journal Paper, Charlotte Hodson,Ambrose Cole,Laurence Lewis,Helen Walden, Nature Structural & Molecular Biology 17 DOI: 10.1038/nsmb.1759 |
| February 2010 | Reengineering orthogonally selective riboswitches Journal Paper, N Dixon,J Duncan,T Geerlings, Dunstan,J McCarthy,David Leys,Jason Micklefield, Proceedings of the National Academy of Sciences 107 PMID: 20133756 |
| February 2010 | Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase Journal Paper, Wyatt Yue,Hozjan Victoria,Christoph Leonarz,Wei Ge,Christopher Cooper,Kathryn Kavanagh,Udo Oppermann,Michael McDonough, FEBS Letters DOI: 10.1016/j.febslet.2009.12.055 PMID: 20067792 |
| February 2010 | The use of novel organic gels and hydrogels in protein crystallization Journal Paper, Zbigniew Jerzy Pietras,H Lin,Sachin Surade,Ben Luisi,O Slattery,K Pos,Abel Moreno Carcamo, Journal of Applied Crystallography 43 DOI: 10.1107/S0021889809051917 |
| January 2010 | Crystal Structure of the Catalytic Domain of Human PARP2 in Complex with PARP Inhibitor ABT-888 Journal Paper, Tobias Karlberg,Martin Hammarstrom,Patrick Schutz,Linda Svensson,Herwig Schuler, Biochemistry DOI: 10.1021/bi902079y |
| January 2010 | The K5 Lyase KflA Combines a Viral Tail Spike Structure with a Bacterial Polysaccharide Lyase Mechanism Journal Paper, Thompson, Pourhossein, Waterhouse, Hudson,Marie Goldrick,Jeremy Derrick,Ian Roberts, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M110.127571 |
| January 2010 | Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase Journal Paper, Wolthers,Colin Levy,Nigel Scrutton,David Leys, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M109.068908 |
| January 2010 | Characterization of wax as a potential diffraction intensity standard for macromolecular crystallography beamlines Journal Paper, Jose Brandao-Neto,Alistair Lennie, Ferreira,Chiu Tang,Stephen Thompson, Journal of Synchrotron Radiation 17 DOI: 10.1107/S0909049509040709 |
| January 2010 | Crystallization and preliminary X-ray analysis of a glucansucrase from the dental caries pathogen Streptococcus mutans Journal Paper, Keisuke Ito , Ito, Shimamura, Kawarasaki, Abe, Misaka, Kobayashi,So Iwata, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 DOI: 10.1107/S1744309110029714 |
| January 2010 | The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. Journal Paper, Smith, Mack, Ebneth, Moraes, Felicetti, Wood, Schonfeld, Mather, Cesura,John Barker, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M109.050062 |
| January 2010 | Retroviral intasome assembly and inhibition of DNA strand transfer Journal Paper, Saumya Shree Gupta,Eugene Valkov,Alan Engelman,Peter Cherepanov,Stephen Hare, Nature DOI: 10.1038/nature08784 |
| January 2010 | Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme Journal Paper, B Adalbjörnsson,H Toogood,A Fryszkowska, Pudney,Thomas Jowitt,David Leys,Nigel Scrutton, Chembiochem 11 PMID: 19943268 |
| January 2010 | The Three-Dimensional Structure of [NiFeSe] Hydrogenase from Desulfovibrio vulgaris Hildenborough: A Hydrogenase without a Bridging Ligand in the Active Site in Its Oxidised, as-Isolated State Journal Paper, Marta Marques,Ricardo Coelho,Antonio De Lacey,Ines Pereira,Pedro Matias, Journal of Molecular Biology DOI: 10.1016/j.jmb.2009.12.013 |
| January 2010 | Structural basis for cofactor-independent dioxygenation of N-heteroaromatic compounds at the / -hydrolase fold Journal Paper, Roberto Steiner,H. J. Janssen,P. Roversi,A. J. Oakley,S. Fetzner, Proceedings of the National Academy of Sciences 107 DOI: 10.1073/pnas.0909033107 |
| December 2009 | Structure of the outer membrane complex of a type IV secretion system. Journal Paper, Vidya Chandran,Remi Fronzes,Stephane Duquerroy,Nora Cronin,Jorge Navaza,Gabriel Waksman, Nature DOI: 10.1038/nature08588. |
| December 2009 | Structural Characterisation of Ligand-Binding Determinants in Human Lung Surfactant Protein D: Influence of Asp325 Journal Paper, Annette Shrive,Chris Martin,Ian Burns,Jenny Paterson,Jackie Martin,Paul Townsend,Paddy Waters,Howard Clark,Uday Kishore,Ken Reid,Trevor Greenhough, Journal of Molecular Biology 394 DOI: 10.1016/j.jmb.2009.09.057 |
| November 2009 | An Auto-Inhibitory Tyrosine Motif in the Cell-Cycle Regulated Nek7 Kinase is Released Through Binding of Nek9 Journal Paper, M Richards,L O'Regan,C Mas-Droux,J Blot,J Cheung,S Hoelder,A Fry,Richard Bayliss, Molecular Cell 36 DOI: 10.1016/j.molcel.2009.09.038 |
| November 2009 | Structure of an Escherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 Å resolution Journal Paper, Ivan Campeotto, Nelson,Andrew Berry, Phillips,Arwen Pearson,Stephen Carr,Chi Hung Trinh, Acta Crystallographica Section F Structural Biology and Crystallization Communications 65 (11) DOI: 10.1107/S1744309109037403 |
| October 2009 | A Supramodular FHA/BRCT-Repeat Architecture Mediates Nbs1 Adaptor Function in Response to DNA Damage Journal Paper, Janette Lloyd,J. Ross Chapman,Julie A. Clapperton,Lesley F. Haire,Edgar Hartsuiker,Jiejin Li,Antony M. Carr,Stephen P. Jackson,Stephen J. Smerdon, Cell 139 DOI: 10.1016/j.cell.2009.07.043 PMID: 19804756 |
| October 2009 | Structural Basis for Substrate Recognition in the Enzymatic Component of ADP-ribosyltransferase Toxin CDTa from Clostridium difficile Journal Paper, Amit Sundriyal,April Roberts,Clifford Shone,Ravi Acharya, Journal of Biological Chemistry 284 DOI: 10.1074/jbc.M109.043018 |
| October 2009 | Crystal Structures of Alpha-Crystallin Domain Dimers of Alphab-Crystallin and Hsp20 Journal Paper, Bagneris,Orval Bateman, Naylor,Nora Cronin, Boelens,Nicholas Keep, Slingsby, Journal of Molecular Biology 392 (5) PMID: 19646995 |
| October 2009 | Specificity and Mechanism of Acinetobacter baumanii Nicotinamidase: Implications for Activation of the Front-Line Tuberculosis Drug Pyrazinamide Journal Paper, Paul Fyfe,Vincenzo Rao,Aleksandra Zemla,Scott Cameron,William N. Hunter, Angewandte Chemie 48 DOI: 10.1002/anie.200903407 |
| October 2009 | Role of the polycomb protein Eed in the propagation of repressive histone marks. Journal Paper, Raphael Margueron,Neil Justin,Katsuhito Ohno,Miriam Sharpe,Jinsook Son,William J Drury III,Philipp Voigt,Stephen Martin,William Taylor,Valeria de Marco,Vincenzo Pirotta,Danny Reinberg,Steven Gamblin, Nature 461 DOI: 10.1038/nature08398 |
| September 2009 | Molecular Architecture of the Mos1 Paired-End Complex: The Structural Basis of DNA Transposition in a Eukaryote Journal Paper, Julia Richardson,Sean D. Colloms,David J. Finnegan,Malcolm Walkinshaw, Cell 138 DOI: 10.1016/j.cell.2009.07.012 PMID: 19766564 |
| August 2009 | HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives Journal Paper, Wang,Huoxing Lei,Xiaofang Wang,Debasis Das,Jian Hong,Colin MacKinnon,Thomas Coulter,Christian A G N. Montalbetti,Richard Mears,Xinjie Gai,Sarah E. Bailey,Donald Ruhrmund,Lisa Hooi,Shawn Misialek,T. Ravi Rajagopalan,Robert K Y Cheng,John Barker, Brunella Felicetti,Dorian L Schönfeld,Antitsa Stoycheva, Bioorganic & medicinal chemistry letters 19(15) DOI: 10.1016/j.bmcl.2009.05.022 |
| July 2009 | Structural Basis for Functional Tetramerization of Lentiviral Integrase Journal Paper, Stephen Hare, Di Nunzio,Alfred Labeja,Jimin Wang,Alan Engelmann,Peter Cherepanov, PLOS Pathogens 5(7) DOI: 10.1371/journal.ppat.1000515 |
| May 2009 | Crystallization and preliminary X-ray analysis of a bifunctional catalase-phenol oxidase from Scytalidium thermophilum Journal Paper, Arwen Pearson,Simon Phillips,Michael McPherson,Didem Kocabas,U Bakir,Z Bakir,Chi Hung Trinh, Acta Crystallographica Section F Structural Biology and Crystallization Communications 65 DOI: 10.1107/S1744309109012007 |
| May 2009 | Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A Journal Paper, Grazyna Kochan,Ewa Pilka,Frank von Delft,Udo Oppermann,Wyatt Yue, Journal of Molecular Biology |
| May 2009 | Structural insight into the quinoloneDNA cleavage complex of type IIA topoisomerases Journal Paper, Ivan Laponogov,Maninder K Sohi,Dennis A Veselkov,Xiao-Su Pan,Ritica Sawhney,Andrew W Thompson,Katherine McAuley,L Mark Fisher,Mark R Sanderson, Nature Structural & Molecular Biology 16 DOI: 10.1038/nsmb.1604 |
| March 2009 | Structures of Leishmania major orthologues of macrophage migration inhibitory factor Journal Paper, Julia Richardson,Lesley S. Morrison,Nicholas D. Bland,Sandra Bruce,Graham H. Coombs,Jeremy C. Mottram,Malcolm D. Walkinshaw, Biochemical and Biophysical Research Communications 380 DOI: 10.1016/j.bbrc.2009.01.030 PMID: 19187777 |
| March 2009 | Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity Journal Paper, C Tron,Iain McNae,M Nutley,D Clarke,A Cooper,Malcolm Walkinshaw,R Baxter,Dominic Campopiano, Journal of Molecular Biology 387(1) DOI: 10.1016/j.jmb.2008.12.086 PMID: 19385043 |
| February 2009 | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS Journal Paper, Duo Lu,Mirka Wormann,Xiaodong Zhang, Schneewind, Grundling, Freemont, Proceedings of the National Academy of Sciences 106 (5) DOI: 10.1073/pnas.0809020106 |
| January 2009 | Specific Recognition of a Multiply Phosphorylated Motif in the DNA Repair Scaffold Xrcc1 by the Fha Domain of Human Pnk. Journal Paper, Ali, Jukes, Pearl,Antony Oliver, Nucleic Acids Research 37 (5) DOI: 10.1093/nar/gkn1086 |
| January 2009 | The Crystal Structure of an Avian IgY-Fc Fragment Reveals Conservation with both Mammalian IgG and IgE Journal Paper, Alexander I. Taylor,Stella M. Fabiane,Brian J. Sutton,Rosaleen A. Calvert, Biochemistry 48 DOI: 10.1021/bi8019993 PMID: 19115948 |
| January 2009 | Overexpression, purification and preliminary X-ray diffraction analysis of the controller protein C.Csp231I from Citrobacter sp RFL231 Journal Paper, Streeter, McGeehan, Kneale, Acta Crystallographica Section F Structural Biology and Crystallization Communications 65 DOI: 10.1107/S1744309109028681 |
| January 2009 | Crystal structure of the human tRNAGly microhelix isoacceptor G9990 at 1.18A resolution Journal Paper, Eichert, Perbandt, Schreiber, Fürste, Betzel, Erdmann, Förster, Biochemical and Biophysical Research Communications 380 DOI: 10.1016/j.bbrc.2009.01.127 |
| December 2008 | Exploring the mechanism of tryptophan 2,3-dioxygenase Journal Paper, Sarah J. Thackray,Christopher G. Mowat,Stephen K. Chapman, Biochemical Society Transactions 36 DOI: 10.1042/BST0361120 PMID: 19021508 |
| December 2008 | The structure of the efflux pump AcrB in complex with bile acid Journal Paper, Klepsch, Newstead,Ralf Flaig, de Gier,Konstantinos Beis, Drew,So Iwata, Molecular Membrane Biology 25 DOI: 10.1080/09687680802552257 PMID: 19023693 |
| December 2008 | Structures of Dimeric Git1 and Trimeric Beta-Pix and Implications for Git-Pix Complex Assembly Journal Paper, Oliver Schlenker, Rittinger, Journal of Molecular Biology 386 DOI: 10.1016/j.jmb.2008.12.050 |
| December 2008 | Structure of the wild-type human BCL6 POZ domain Journal Paper, Mark Stead,Gareth Rosbrook,Jonathan Hadden,Chi Hung Trinh,Stephen Carr,Stephanie Wright, Acta Crystallographica Section F Structural Biology and Crystallization Communications 64 DOI: 10.1107/S1744309108036063 |
| October 2008 | Molecular Architecture of the "Stressosome" a Signal Integration and Transduction Hub Journal Paper, Jon Marles-Wright,Tim Grant,Olivier Delumeau,Gijs van Duinen,Susan Firbank,Peter J Lewis,James W Murray,Joseph A Newman,Maureen Quin,Paul Race, Science 322 DOI: 10.1126/science.1159572 |
| October 2008 | The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines. Journal Paper, Kadlec, Loureiro, Jones,Nicola Abrescia,Dave Stuart, Nature Structural & Molecular Biology 10 PMID: 18776902 |
| October 2008 | Structural Analysis of the Interactions Between Paxillin LD Motifs and alpha-Parvin Journal Paper, Lorenz,John Vakonakis,Iain Campbell,Maria Hoellerer,Nathan Lack,Ed Lowe, Structure 8 (16) DOI: 10.1016/j.str.2008.08.007. |
| October 2008 | Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization. Journal Paper, Massayuki Yamasaki,Li Wei Li,Daniel Johnson,Jim Huntington, Nature 455(7217) PMID: 18923394 |
| September 2008 | Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography Journal Paper, Susan Firbank,Josephine Wardle,Pauline Heslop,Rick Lewis,Bernard Connolly, Journal of Molecular Biology 381 DOI: 10.1016/j.jmb.2008.06.004 | |
| September 2008 | Evidence That Two Enzyme-derived Histidine Ligands Are Sufficient for Iron Binding and Catalysis by Factor Inhibiting HIF (FIH) Journal Paper, Hewitson, Holmes, Ehrismann, Hardy,Rasheduzzaman Chowdhury, Schofield,Michael McDonough, Journal of Biological Chemistry 283 (38) DOI: 10.1074/jbc.M804999200 |
| August 2008 | Macromolecular crystallography at Diamond Light Souce: Automation and pathogenic sample environment Journal Paper, Dave Hall,Alun Ashton,Jose Brandao-Neto,David Butler,Liz Duke,Gwyndaf Evans,Ralf Flaig, Foster,Paul Gibbons,Mic Harding,Mike Latchem,Karl Levik,Katherine McAuley,James O'Hea,Geoff Preece,James Sandy, Waterman, Williams,Richard Woolliscroft,Thomas Sorensen, Acta Crystallographica Section A Foundations of Crystallography 64 |
| August 2008 | The Structure of a Chondroitin Sulfate-binding Domain Important in Placental Malaria Journal Paper, Matthew Higgins, Journal of Biological Chemistry 283 (21) DOI: 10.1074/jbc.C800086200 |
| August 2008 | Experience from operation and commissioning of the Phase 1 MX beamlines at Diamond Light Source Conference Paper, Ralf Flaig,Alun Ashton,Jose Brandao-Neto,Liz Duke,Gwyndaf Evans, Foster,Paul Gibbons,Arno Grant,Dave Hall,Mike Latchem,Karl Levik,Katherine McAuley,James O'Hea,Geoff Preece,James Sandy,Thomas Sorensen,David Waterman,Richard Woolliscroft, null |
| July 2008 | Targeted rescue of a destabilized mutant of p53 by an in silico screened drug Journal Paper, Frank Boeckler,Andreas Christian Joerger,Gaurav Jaggi,Trevor Rutherford, Veprintsev, Fersht, Proceedings of the National Academy of Sciences 105 (30) DOI: 10.1073/pnas.0805326105 |
| June 2008 | Structure and Mechanism of an Unusual Malonate Decarboxylase and Related Racemases. Journal Paper, Okrasa,Colin Levy, Hauer, Baudendistel,David Leys, Micklefield, Chemistry - A European Journal 14 DOI: 10.1002/chem.200800918 |
| June 2008 | The FACT Spt16 'peptidase' domain is a histone H3'H4 binding module Journal Paper, Tobias Stuwe,Michael Hothorn,Erwan Lejeune,Vladimir Rybin,Miriam Bortfeld,Klaus Scheffzek,Andreas Ladurner, Proceedings of the National Academy of Sciences 105 no 26 DOI: 10.1073/pnas.0712293105 |
| March 2008 | Crystallization and preliminary X-ray analysis of RsbS from Moorella thermoacetica at 2.5 A resolution Journal Paper, Susan Firbank,Rick Lewis,Jon Marles-Wright,Joseph A Newman,Maureen Quin, Acta Crystallographica Section F Structural Biology and Crystallization Communications 64 (Pt 3) PMID: 18323607 |
| January 2008 | Structure of the topoisomerase IV from S. pneumoniae with a DNA target and quinolone drug Poster, Ivan Laponogov,Maninder Sohi,Dennis Veselkov, Pan, Sawhney, Thompson,Mark Fisher,Mark Sanderson, Acta Crystallographica Section A Foundations of Crystallography 64 |
| December 2007 | Structure of HsaD, a steroid-degrading hydrolase, from Mycobacterium tuberculosis. Journal Paper, Nathan Lack, Liu, Eltis, Noble, Sim,Ed Lowe,Isaac Westwood, Acta Crystallographica Section F Structural Biology and Crystallization Communications PMID: 2373992 |
| August 2007 | Commissioning Progress at Diamond Light Source. Conference Paper, Ralf Flaig, null |
| May 2007 | Crystallization and preliminary X-ray analysis of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase from Arthrobacter nitroguajacolicus Ru61a: a cofactor-devoid dioxygenase of the alpha/beta hydrolase-fold superfamily Journal Paper, Roberto Steiner,U Frerichs-Deeken,Susan Fetzner, Acta Crystallographica Section F Structural Biology and Crystallization Communications 63 PMID: 17565176 |