These publications are based on data gathered on beamline I03. If you are aware of any errors or publications that should be listed here, please send details to Sara Fletcher.
Total: 221 publications
| Date∇ | Publication details∇ |
|---|---|
| March 2012 | Insights into dynein motor domain function from a 3.3-Å crystal structure Journal Paper, Helgo Schmidt,Emma S Gleave,Andrew P Carter, Nature Structural & Molecular Biology DOI: 10.1038/nsmb.2272 |
| February 2012 | Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex Journal Paper, Andrew M Ellisdon,Lyudmila Dimitrova,Ed Hurt,Murray Stewart, Nature Structural & Molecular Biology 19 DOI: 10.1038/nsmb.2235 |
| February 2012 | Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors Journal Paper, Elisabet Wahlberg,Tobias Karlberg,Ekaterina Kouznetsova,Natalia Markova,Antonio Macchiarulo,Ann-Gerd Thorsell,Ewa Pol,Åsa Frostell,Torun Ekblad,Delal Öncü,Björn Kull,Graeme Michael Robertson,Roberto Pellicciari,Herwig Schüler,Johan Weigelt, Nature Biotechnology 30 DOI: 10.1038/nbt.2121 |
| February 2012 | An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid Journal Paper, Marc de la Roche,Trevor J. Rutherford,Deepti Gupta,Dmitry B. Veprintsev,Barbara Saxty,Stefan M. Freund,Mariann Bienz, Nature Communications 3 DOI: 10.1038/ncomms1680 |
| January 2012 | Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands Journal Paper, Gavin Collie,Rossella Promontorio,Sonja M Hampel,Marialuisa Micco,Stephen Neidle,Gary Parkinson, Journal of the American Chemical Society DOI: 10.1021/ja2102423 |
| January 2012 | Structural and mechanistic insight into N-glycan processing by endo- -mannosidase Journal Paper, Andrew Thompson,R. J. Williams,Z. Hakki,D. S. Alonzi,T. Wennekes,T. M. Gloster,K. Songsrirote,J. E. Thomas-Oates,T. M. Wrodnigg,J. Spreitz,A. E. Stutz,T. D. Butters,S. J. Williams,G. J. Davies, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1111482109 |
| January 2012 | Structure and Mechanism of the CMR Complex for CRISPR-Mediated Antiviral Immunity Journal Paper, Jing Zhang,Christophe Rouillon,Melina Kerou,Judith Reeks,Kim Brugger,Shirley Graham,Julia Reimann,Giuseppe Cannone,Huanting Liu,Sonja-Verena Albers,James Naismith,Laura Spagnolo,Malcolm F. White, Molecular Cell DOI: 10.1016/j.molcel.2011.12.013 |
| January 2012 | Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation Journal Paper, D. Wei,G. N. Parkinson,A. P. Reszka,S. Neidle, Nucleic Acids Research DOI: 10.1093/nar/gks023 |
| December 2011 | Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis Journal Paper, Apirat Chaikuad,D. S. Froese,G. Berridge,Frank von Delft,Udo Oppermann,Wyatt Yue, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1113921108 |
| December 2011 | The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly Journal Paper, Nia L. Marrott,Jacqueline Marshall,Dmitri Svergun,Susan Crennell,David Hough,Michael Danson,Jean van den Elsen, FEBS Journal DOI: 10.1111/j.1742-4658.2011.08461.x |
| December 2011 | Structures of engineered Clostridium botulinum neurotoxin derivatives Journal Paper, Geoffrey Masuyer,Patrick Stancombe,John Chaddock,Ravi Acharya, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 DOI: 10.1107/S1744309111034671 |
| December 2011 | Challenges of sulfur SAD phasing as a routine method in macromolecular crystallography Report, James Doutch,Mike Hough,Samar Hasnain,Richard W. Strange, Journal of Synchrotron Radiation 19 DOI: 10.1107/S0909049511049004 |
| December 2011 | Inhibition of Apoptosis and NF-κB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence Journal Paper, Carlos Maluquer de Motes,Samantha Cooray,Hongwei Ren,Gabriel M. F. Almeida,Kieran McGourty,Mohammad W. Bahar,David I. Stuart,Jonathan M. Grimes,Stephen C. Graham,Geoffrey L. Smith,Michele Barry, PLoS Pathogens 7 DOI: 10.1371/journal.ppat.1002430 |
| November 2011 | Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation Journal Paper, Alex Gingras,Umakhanth Venkatraman Girija,Anthony H. Keeble,Roshni Panchal,Daniel A. Mitchell,Peter Moody,Russell Wallis, Structure 19 DOI: 10.1016/j.str.2011.08.014 |
| November 2011 | Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII Journal Paper, Martin Moncrieffe,Maria-Jose Fernandez,Dieter Spiteller,Hiroyoshi Matsumura,Nicholas Gay,Ben Luisi,Peter Leadlay, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.10.036 |
| November 2011 | PNAS Plus: Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales Journal Paper, Sonia Paytubi,Stephen McMahon,S. Graham,H. Liu,C. H. Botting,K. S. Makarova,Eugene Koonin,James Naismith,M. F. White, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1113277108 |
| November 2011 | A novel technique combining high-resolution synchrotron x-ray microtomography and x-ray diffraction for characterization of micro particulates Journal Paper, David Merrifield,Vasuki Ramachandran,Kevin J Roberts,Wes Armour,Danny Axford,Mark Basham,Thomas Connolley,Gwyndaf Evans,Katherine McAuley,Robin Owen,James Sandy, Measurement Science and Technology 22 DOI: 10.1088/0957-0233/22/11/115703 |
| November 2011 | Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes Journal Paper, Nancy Campbell,Nurul Karim,Gary Parkinson,Mekala Gunaratnam,Vanessa Petrucci,Alan K Todd,Ramon Vilar,Stephen Neidle, Journal of Medicinal Chemistry DOI: 10.1021/jm201140v |
| November 2011 | The Molecular Basis for the Endocytosis of Small R-SNAREs by the Clathrin Adaptor CALM Journal Paper, Sharon Miller,Daniela A. Sahlender,Stephen C. Graham,Stefan Honing,Margaret S. Robinson,Andrew A. Peden,David Owen, Cell 147 DOI: 10.1016/j.cell.2011.10.038 |
| November 2011 | Structure and Kinetic Stability of the p63 Tetramerization Domain Journal Paper, Eviata Najan,Andreas Christian Joerger, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.11.007 |
| November 2011 | The Structural Basis for Substrate Recognition by Mammalian Polynucleotide Kinase 3′ Phosphatase Journal Paper, Fernando Garces,Laurence H Pearl,Antony Oliver, Molecular Cell 44 DOI: 10.1016/j.molcel.2011.08.036 |
| November 2011 | Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor Journal Paper, Geoffrey Masuyer,Talat Jabeen,Christopher T. Öberg,Hakon Leffler,Ulf J. Nilsson,Ravi Acharya, FEBS Journal DOI: 10.1111/j.1742-4658.2011.08414.x |
| October 2011 | Structural variability of the Ubiquitin Specific Protease DUSP-UBL double domains Journal Paper, Paul Elliott,Han Liu,Martyna W. Pastok,Guenter Grossmann,Daniel J. Rigden,Michael J. Clague,Sylvie Urbé,Igor L. Barsukov, FEBS Letters DOI: 10.1016/j.febslet.2011.09.040 |
| October 2011 | X-ray structure of the dimeric cytochrome bc1 complex from the soil bacterium Paracoccus denitrificans at 2.7-Å resolution Journal Paper, Thomas Kleinschroth,Michela Castellani,Chi Hung Trinh,Nina Morgner,Bernhard Brutschy,Bernd Ludwig,Carola Hunte, Biochimica et Biophysica Acta (BBA) - Bioenergetics DOI: 10.1016/j.bbabio.2011.09.017 |
| October 2011 | Kinked b-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL Journal Paper, Huw Jenkins,Bara Malkova,Thomas Edwards, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1105211108 |
| October 2011 | Characterisation of an oxidoreductase from the Arylamine N-acetyltransferase operon in Mycobacterium smegmatis Journal Paper, Jim Evangelopoulos,Nora Cronin,Tina Daviter,Edith Sim,Nicholas Keep,Sanjib Bhakta, FEBS Journal DOI: 10.1111/j.1742-4658.2011.08382.x |
| October 2011 | High-throughput identification of purification conditions leads to preliminary crystallization conditions for three inner membrane proteins Journal Paper, Mads Gabrielsen,Frank Kroner,Isobel Black,Neil Isaacs,Andrew J. Roe,Karen McLuskey, Molecular Membrane Biology 28 DOI: 10.3109/09687688.2011.628954 |
| September 2011 | Structure of a Streptomyces maltosyltransferase GlgE: a homologue of a genetically validated anti-tuberculosis target Journal Paper, K. Syson,C. E. M. Stevenson,M. Rejzek,S. A. Fairhurst,A. Nair,C. J. Bruton,R. A. Field,K. F. Chater,D. M. Lawson,S. Bornemann, Journal of Biological Chemistry DOI: 10.1074/jbc.M111.279315 |
| September 2011 | Structural basis for cell surface patterning through NetrinGNGL interactions Journal Paper, Elena Seiradake,Charlotte H Coles,Pavel V Perestenko,Karl Harlos,Robert Andrew Jeffrey McIlhinney,Alexandru Aricescu,Yvonne Jones, The EMBO Journal DOI: 10.1038/emboj.2011.346 |
| September 2011 | Altering the stability of the Cdc8 overlap region modulates the ability of this tropomyosin to bind co-operatively to actin and regulate myosin Journal Paper, Daniel A. East,Duncan Sousa,Stephen Martin,Thomas Edwards,William Lehman,Daniel P. Mulvihill, Biochemical Journal 438 DOI: 10.1042/BJ20101316 |
| September 2011 | Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway Journal Paper, Charlotte Hodson,Ambrose Cole,Laurence Lewis,J. A. Miles,A. Purkiss,Helen Walden, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M111.244632 PMID: 21775430 |
| September 2011 | Non-equivalent role of inter- and intra-molecular hydrogen bonds in the insulin dimer interface Journal Paper, Antolikova, Zakova,Johan Turkenburg,C. J. Watson,I. Hanclova,M. Sanda,A. Cooper,T. Kraus, Brzozowski,J. Jiracek, Journal of Biological Chemistry DOI: 10.1074/jbc.M111.265249 |
| September 2011 | A widespread family of bacterial cell wall assembly proteins Journal Paper, Yoshikazu Kawai,Jon Marles-Wright,Robert M Cleverley,Robyn Emmins,Shu Ishikawa,Masayoshi Kuwano,Nadja Heinz,Nhat Khai Bui,Christopher N Hoyland,Naotake Ogasawara,Rick Lewis,Waldemar Vollmer,Richard A Daniel,Jeff Errington, The EMBO Journal DOI: 10.1038/emboj.2011.358 |
| September 2011 | Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases. Journal Paper, Wai-Ching Hon,Alex Berndt,Roger Williams, Oncogene |
| September 2011 | The three-dimensional structure of mannosyl-3-phosphoglycerate phosphatase from <i>Thermus thermophilus</i> HB27: a new member of the Haloalkanoic Acid Dehalogenase Superfamily Journal Paper, Susana Goncalves,Ana Esteves,Helena Santos,Nuno Borges,Pedro Matias, Biochemistry DOI: 10.1021/bi201171h |
| September 2011 | Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins Journal Paper, Svetlana Antonyuk,Neil Rustage,C. A. Petersen,J. L. Arnst,Derren Heyes,R. Sharma,Neil Berry, Scrutton,Robert Eady,C. R. Andrew,Samar Hasnain, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1109051108 |
| September 2011 | Structural Basis for the broad tissue tropism of the pathogenic fungus Candida Albicans Journal Paper, Paula Salgado,Robert Yan,Jon Taylor,Lynne Buchnell,Rhian Jones, Hoyer,Steve Matthews,Peter Simpson,Ernesto Cota-Segura, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1103496108 |
| September 2011 | Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT Journal Paper, Nien-Jen Hu,So Iwata,Alex Cameron, Drew, Nature DOI: 10.1038/nature10450 |
| August 2011 | The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding Journal Paper, Tung Le,M. A. Schumacher,David Lawson,R. G. Brennan,Mark Buttner, Nucleic Acids Research DOI: 10.1093/nar/gkr640 |
| August 2011 | A Dual Binding Mode for RhoGTPases in Plexin Signalling Journal Paper, Christian Bell,A. Radu Aricescu,E. Yvonne Jones,Christian Siebold,Gregory A. Petsko, PLoS Biology 9 DOI: 10.1371/journal.pbio.1001134 |
| August 2011 | Structure and Organisation of SinR, the Master Regulator of Biofilm Formation in Bacillus subtilis Journal Paper, Vicki L. Colledge,Mark J. Fogg,Vladimir M. Levdikov,Andrew Leech,Eleanor J. Dodson,Anthony J. Wilkinson, Journal of Molecular Biology 411 DOI: 10.1016/j.jmb.2011.06.004 |
| August 2011 | A Neutralizing Antibody Selected from Plasma Cells That Binds to Group 1 and Group 2 Influenza A Hemagglutinins Journal Paper, D. Corti,J. Voss,Steven Gamblin,G. Codoni,A. Macagno,D. Jarrossay,S. G. Vachieri,D. Pinna,A. Minola,F. Vanzetta,C. Silacci,B. M. Fernandez-Rodriguez,G. Agatic,S. Bianchi,I. Giacchetto-Sasselli,L. Calder,F. Sallusto,P. Collins,L. F. Haire,N. Temperton, Science 333 DOI: 10.1126/science.1205669 PMID: 21798894 |
| August 2011 | Insights into Krabbe disease from structures of galactocerebrosidase Journal Paper, Janet E Deane,Stephen Graham,N. N. Kim,P. E. Stein,R. McNair,M. B. Cachon-Gonzalez,T. M. Cox,Randy Read, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1105639108 |
| July 2011 | Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1 Journal Paper, Tomas Malinauskas,Alexandru Aricescu,Weixian Lu,Christian Siebold,Yvonne Jones, Nature Structural & Molecular Biology 18 DOI: 10.1038/nsmb.2081 |
| July 2011 | Crystal Structure of Serratia fonticola Sfh-I: Activation of the Nucleophile in Mono-Zinc Metallo-beta-Lactamases Journal Paper, Fatima Fonseca,Elizabeth Bromley,Maria José Saavedra,António Correia,Jim Spencer, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.06.043 |
| July 2011 | The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site Journal Paper, Hugh Morgan,Iain McNae,Matthew Nowicki,W. Zhong,P. A. M. Michels,D. S. Auld,L. A. Fothergill-Gilmore,Malcolm Walkinshaw, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M110.212613 PMID: PMC3173065 |
| July 2011 | Crystallographic determination of the disease-associated T1184R variant of complement regulator factor H Journal Paper, Hugh Morgan,Jingzi Jiang,Andrew P. Herbert,David Kavanagh,Duan Uhrin,Paul N. Barlow,Jonathan Hannan, Acta Crystallographica Section D Biological Crystallography 67 DOI: 10.1107/S0907444911015423 PMID: 21697597 |
| July 2011 | Structure of the Drosophila melanogaster Rab6 GTPase at 1.4 Å resolution Journal Paper, Miriam Walden,Huw Jenkins,Thomas Edwards, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 DOI: 10.1107/S1744309111017453 |
| July 2011 | Insights into the Evolution of a Complex Virus from the Crystal Structure of Vaccinia Virus D13 Journal Paper, Mohammad Bahar,Stephen Graham,Dave Stuart,Jonathan Grimes, Structure 19 (7) DOI: 10.1016/j.str.2011.03.023 |
| July 2011 | Structure and Mechanism of Human UDP-glucose 6-Dehydrogenase Journal Paper, S. Egger,Apirat Chaikuad,Kathryn Kavanagh,Udo Oppermann,B. Nidetzky, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M111.234682 |
| July 2011 | Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90 Journal Paper, Stefan Millson,C.-S. Chua,Mark Roe,S. Polier,S. Solovieva,L. H. Pearl,T.-S. Sim,C. Prodromou,P. W. Piper, The FASEB Journal DOI: 10.1096/fj.11-188821 PMID: 21778327 |
| July 2011 | Structural and Functional Analyses of the Second-generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572) Journal Paper, Stephen Hare,S. J. Smith,M. Metifiot,A. Jaxa-Chamiec,Y. Pommier,S. H. Hughes,Peter Cherepanov, Molecular Pharmacology DOI: 10.1124/mol.111.073189 |
| June 2011 | The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor Journal Paper, Li Zhang,Louise Fairall,Benjamin Goult,Anna Calkin,Cynthia Hong,Chris Millard,Peter Tontonoz,John Schwabe, Genes & Development 25 DOI: 10.1101/gad.2056211 |
| June 2011 | Mapping Lipid and Detergent Molecules at the Surface of Membrane Proteins Conference Paper, Richard Cogdell, null PMID: 21599648 |
| June 2011 | Simultaneous X-ray diffraction from multiple single crystals of macromolecules Journal Paper, Karthik Paithankar,Henning O. Sørensen,Jonathan P. Wright,Søren Schmidt,Henning F. Poulsen,Elspeth F. Garman, Acta Crystallographica Section D Biological Crystallography 67 DOI: 10.1107/S0907444911015617 |
| June 2011 | X-ray Crystallographic Structure of the Murine Norovirus protease at 1.66 Å Resolution and Functional Studies of the β-ribbon Thesis, Gabriela Baeza, null |
| June 2011 | The Virulence Factor PEB4 (Cj0596) and the Periplasmic Protein Cj1289 Are Two Structurally Related SurA-like Chaperones in the Human Pathogen Campylobacter jejuni Journal Paper, A. Kale,C. Phansopa,C. Suwannachart,C. J. Craven,J. B. Rafferty,D. J. Kelly, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M111.220442 |
| May 2011 | Assessment of radiation damage behaviour in a large collection of empirically optimized datasets highlights the importance of unmeasured complicating effects Journal Paper, Tobias Krojer,Frank von Delft, Journal of Synchrotron Radiation 18 (3) DOI: 10.1107/S0909049511008235 |
| May 2011 | The structure of a Burkholderia pseudomallei immunophilininhibitor complex reveals new approaches to antimicrobial development Journal Paper, Isobel Norville,Katherine O'Shea,Mitali Sarkar‑Tyson,Suxin Zheng,Richard Titball,Gabriele Varani,Nicholas Harmer, Biochemical Journal 437 DOI: 10.1042/BJ20110345 |
| May 2011 | Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming Journal Paper, Grazyna Kochan,Tobias Krojer,D. Harvey,R. Fischer,L. Chen,M. Vollmar,Frank von Delft,Kathryn Kavanagh,M. A. Brown,P. Bowness,P. Wordsworth,B. M. Kessler,Udo Oppermann, Proceedings of the National Academy of Sciences 108 DOI: 10.1073/pnas.1101262108 |
| April 2011 | From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo-Like Kinase 1 Journal Paper, Pawel Sledz,Christopher Stubbs,Steffen Lang,Yong-Qing Yang,Grahame McKenzie,Ashok Venkitaraman,Marko Hyvonen,Chris Abell, Angewandte Chemie 123 (17) DOI: 10.1002/ange.201008019 |
| April 2011 | Proteoglycan-Specific Molecular Switch for RPTP Clustering and Neuronal Extension Journal Paper, C. H. Coles,Y. Shen,A. P. Tenney,Christian Siebold,G. C. Sutton,W. Lu,J. T. Gallagher,E. Y. Jones,J. G. Flanagan,Alexandru Aricescu, Science 332 DOI: 10.1126/science.1200840 |
| April 2011 | Structure and activity of a functional derivative of Clostridium botulinum neurotoxin Journal Paper, Geoffrey Masuyer,Matthew Beard,Verity Cadd,John Chaddock,Ravi Acharya, Journal of Structural Biology 174 DOI: 10.1016/j.jsb.2010.11.010 |
| April 2011 | Expression, crystallization and preliminary X-ray data analysis of NT-ALS9, a fungal adhesin from Candida albicans Journal Paper, Paula Salgado,Robert Yan,Rowantree Niall,Ernesto Cota-Segura, Acta Crystallographica Section F Structural Biology and Crystallization Communications DOI: 10.1107/S1744309111003460 |
| March 2011 | Dynamics and allosteric potential of the AMPA receptor N-terminal domain Journal Paper, Madhav Sukumaran,Maxim Rossmann,I shrivastava,A Dutta,I Bahar,Ingo Greger, The EMBO Journal 30 DOI: 10.1038/emboj.2011.17 |
| March 2011 | Helix-mediated protein-protein interactions as targets for intervention using foldamers Journal Paper, Thomas Edwards,Andrew Wilson, Amino Acids DOI: 10.1007/s00726-011-0880-8 |
| March 2011 | Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers. Journal Paper, Maxim Rossmann,Madhav Sukumaran,A Penn, Veprintsev,Madan Babu,Ingo Greger, The EMBO Journal 30 DOI: 10.1038/emboj.2011.16 |
| March 2011 | Structure of mammalian AMPK and its regulation by ADP Journal Paper, Bing Xiao,Matthew J. Sanders,Elizabeth Underwood,Richard Heath,Faith V. Mayer,David Carmena,Chun Jing,Philip A. Walker,John F. Eccleston,Lesley F. Haire,Peter Saiu,Steven A. Howell,Rein Aasland,Stephen R. Martin,David Carling,Steven J. Gamblin, Nature 472 DOI: 10.1038/nature09932 PMID: 21399626 |
| March 2011 | Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure−Activity Relationship Journal Paper, Richard Bayliss,C Mas-Droux,Rob van Montfort, J Med Chem. 54 PMID: 21366329 |
| March 2011 | Understanding small-molecule binding to MDM2: Insights into structural effects of isoindolinone inhibitors from NMR spectroscopy Journal Paper, Christiane Riedinger,Martin Noble, Wright, Mulks, Hardcastle,Jane Endicott, McDonnell , Chemical Biology and Drug Design DOI: 10.1111/j.1747-0285.2011.01091.x |
| March 2011 | Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking Journal Paper, Peter Daldrop,Francis Reyes,David Robinson,Colin Hammond,David Lilley,Robert Batey,Ruth Brenk, Chemistry - A European Journal 18 (3) DOI: 10.1016/j.chembiol.2010.12.020 |
| February 2011 | Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism Journal Paper, Gamble,Georg Kunze, Dodson,Keith Wilson,Dafydd Jones, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1014229108 |
| February 2011 | Novel mechanism of inhibition of human Angiotensin-I converting enzyme (ACE) by a highly specific phosphinic tripeptide Journal Paper, Akif Mohd,Sylva Schwager,Colin Anthony,Bertrand Czarny,Fabrice Beau,Edward Sturrock,Ravi Acharya, Biochemical Journal DOI: 10.1042/BJ20102123 |
| February 2011 | Conformational Flexibility of the Ligand-Binding Domain Dimer in Kainate Receptor Gating and Desensitization Journal Paper, Naushaba Nayeem,Olga Mayans,Tim Green, Journal of Neuroscience 31 (8) DOI: 10.1523/​JNEUROSCI.4771-10.2011 |
| February 2011 | Substrate and metal-ion promiscuity in mannosylglycerate synthase Journal Paper, Morten Nielsen,Michael Suits,Min Yang,Conor Barry,Carlos Martinez-Fleites,Louise Tailford,James Flint, Dumon,Benjamin Davis,Harry Gilbert,Gideon Davies, Journal of Biological Chemistry DOI: 10.1074/jbc.M110.199844 |
| February 2011 | Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response Journal Paper, Maruf M U Ali,Tina Bagratuni,Emma L Davenport,Piotr R Nowak,M Cris Silva-Santisteban,Anthea Hardcastle,Craig McAndrews,Martin G Rowlands,Gareth J Morgan,Wynne Aherne,Ian Collins,Faith E Davies,Laurence H Pearl, The EMBO Journal 30 DOI: 10.1038/emboj.2011.18 PMID: 21317875 |
| February 2011 | Crystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a Groove Journal Paper, A. Clark, Naylor,Claire Bagneris,Nicholas Keep, Slingsby, Journal of Molecular Biology 408 DOI: 10.1016/j.jmb.2011.02.020 |
| February 2011 | Structures of the TetR-like simocyclinone efflux pump repressor, SimR, and the mechanism of ligand-mediated derepression Journal Paper, Tung Le,Clare Stevenson,Hans-Peter Fiedler,Anthony Maxwell,David Lawson,Mark Buttner, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.02.035 |
| February 2011 | Structural basis for engagement by complement factor H of C3b on a self surface Journal Paper, Hugh P Morgan,Christoph Q Schmidt,Mara Guariento,Bärbel S Blaum,Dominic Gillespie,Andrew P Herbert,David Kavanagh,Haydyn D T Mertens,Dmitri I Svergun,Conny M Johansson,Duan Uhrín,Paul N Barlow,Jonathan P Hannan, Nature Structural & Molecular Biology 18 DOI: 10.1038/nsmb.2018 |
| February 2011 | Crystallization and preliminary X-ray analysis of the TetR-like efflux pump regulator SimR Journal Paper, Tung Le,Clare Stevenson,Mark Buttner,David Lawson, Acta Crystallographica Section F Structural Biology and Crystallization Communications 67 (3) DOI: 10.1107/S1744309110053078 |
| February 2011 | A hyperactive cobalt-substituted extradiol-cleaving catechol dioxygenase Journal Paper, Andrew Fielding,Elena Kovaleva,Erik Farquhar,John Lipscomb,Laurence Que, Jr., Journal of Biological Chemistry 16 DOI: 10.1007/s00775-010-0732-0 |
| February 2011 | Structure-Activity Relationship and Multidrug Resistance Study of New S-trityl-L-Cysteine Derivatives As Inhibitors of Eg5 Journal Paper, Kristal Kaan,Johanna Weiss,Dominik Menger,Venkat Ulaganathan,Katarzyna Tkocz,Christian Laggner,Florence Popowycz,Benoit Joseph,Frank Kozielski, Journal of Medicinal Chemistry DOI: 10.1021/jm100991m |
| January 2011 | Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS Journal Paper, Apirat Chaikuad, Shafqat, Al-Mokhtar, Cameron, Clarke, Brady, Oppermann, Frayne, Yue, Biochemical Journal 435 DOI: 10.1042/BJ20101442 |
| January 2011 | Identification of Macrodomain Proteins as Novel O-Acetyl-ADP-ribose Deacetylases Journal Paper, Dawei Chen, Vollmar, Rossi, Phillips, Kraehenbuehl, Slade, Mehrotra,Frank von Delft, Crosthwaite, Gileadi, Denu, Ahel, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M110.206771 |
| January 2011 | Structure and mechanism of the chalcogen detoxifying protein TehB from Escherichia coli Journal Paper, Hassan Choudhury,Alex Cameron,So Iwata,Konstantinos Beis, Biochemical Journal DOI: 10.1042/BJ20102014 |
| January 2011 | Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery Journal Paper, Jasmeen Oberoi,Louise Fairall,Peter J Watson,Ji-Chun Yang,Zsolt Czimmerer,Thorsten Kampmann,Ben Goult,Jacquie Greenwood,John Gooch,Bettina Kallenburger,Laszlo Nagy,David Neuhaus,John Schwabe, Nature Structural & Molecular Biology 18 DOI: 10.1038/nsmb.1983 |
| January 2011 | Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2 Journal Paper, John J. Caldwell,Emma J. Welsh,Cornelis Matijssen,Victoria E. Anderson,Laurent Antoni,Kathy Boxall,Frederique Urban,Angela Hayes,Florence I. Raynaud,Laurent J. M. Rigoreau,Tony Raynham,G. Wynne Aherne,Laurence H. Pearl,Antony W. Oliver,Michelle D. Garrett,Ian Collins, Journal of Medicinal Chemistry 54 DOI: 10.1021/jm101150b PMID: 21186793 |
| January 2011 | Structure of rhomboid protease in a lipid environment Journal Paper, Kutti Vinothkumar, Journal of Molecular Biology DOI: 10.1016/j.jmb.2011.01.029 |
| January 2011 | Dissecting the mechanism of oxygen trafficking in a metalloenzyme Journal Paper, Mark Smith,Peter Knowles,Michael McPherson,Arwen Pearson, Faraday Discussions 148 DOI: 10.1039/c005054g |
| January 2011 | Extending the usability of the phasing power of diselenide bonds: SeCys SAD phasing of CsgC using a non-auxotrophic strain. Journal Paper, Paula Salgado,Jon Taylor,Ernesto Cota-Segura,Steve Matthews, Acta Crystallogr D Biol Crystallogr 67 DOI: 10.1107/S0907444910042022 |
| January 2011 | Phosphotyrosine recognition by the Raf Kinase Inhibitor Protein Journal Paper, Philip Simister,Nick Burton,Leo Brady, Forum on Immunopathological Diseases and Therapeutics 2(1) DOI: 10.1615/ForumImmunDisTher.v2.i1.70 |
| January 2011 | The structure of human complement factor I Conference Paper, Pietro Roversi,Steven Johnson, null |
| January 2011 | Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2. Journal Paper, Simon Newstead ,David Drew,Alexander Cameron,Vincent Postis,Xiaobing Xia,Philip Fowler,Jean Ingram,Elisabeth Carpenter,Mark Sansom,Michael McPherson,Stephen Baldwin,So Iwata, The EMBO Journal PMID: 21131908 |
| January 2011 | Monitoring and validating active site redox states in protein crystals Journal Paper, Svetlana Antonyuk,Mike Hough, Biochimica et Biophysica Acta (BBA) DOI: 10.1016/j.bbapap.2010.12.017 |
| January 2011 | A processed noncoding RNA regulates an altruistic bacterial antiviral system Journal Paper, Tim Blower,Xue-Yuan Pei,Francesca Short,P Fineran,David Humphreys,Ben Luisi,George Salmond, Nature Structural & Molecular Biology 18 DOI: 10.1038/nsmb.1981 |
| January 2011 | CCT241533 Is a Potent and Selective Inhibitor of CHK2 that Potentiates the Cytotoxicity of PARP Inhibitors Journal Paper, Victoria E. Anderson,M. I. Walton,P. D. Eve,Kathy Boxall,L. Antoni,J. J. Caldwell,W. Aherne,L. H. Pearl,A. W. Oliver,I. Collins,M. D. Garrett, Cancer Research 71 DOI: 10.1158/0008-5472.CAN-10-1252 PMID: 21239475 |
| January 2011 | Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis Journal Paper, Wen-Jun Gui,Shi-Qiang Lin,Yuan-Yuan Chen,Xian-En Zhang,Li-Jun Bi,Tao Jiang, Biochemical and Biophysical Research Communications DOI: 10.1016/j.bbrc.2011.01.027 |
| January 2011 | Structural insights into quinolone antibiotic resistance mediated by pentapeptide repeat proteins: conserved surface loops direct the activity of a Qnr protein from a Gram-negative bacterium Journal Paper, Xiaoli Xiong,Elizabeth Bromley,Peter Oelschlaeger,Derek Woolfson,Jim Spencer, Nucleic Acids Research 39 (1) DOI: 10.1093/nar/gkq1296 |
| January 2011 | Structural and functional characterization of Pseudomonas aeruginosa CupB chaperones. Journal Paper, Xun Cai,Rui Wang,Alain Filloux,Gabriel Waksman,Goyu Meng, PLoS One DOI: 10.1371/journal.pone.0016583 |
| December 2010 | Structural and Mechanistic Studies on γ-Butyrobetaine Hydroxylase Journal Paper, Ivanhoe K.H. Leung,Tobias Krojer,Grazyna Kochan,Luc Henry,Frank von Delft,Timothy D.W. Claridge,Udo Oppermann,Michael McDonough,Christopher J. Schofield, Chemistry & Biology 17 DOI: 10.1016/j.chembiol.2010.09.016 |
| December 2010 | TOPSORT: TCR optimized peptide skewing of the repertoire of T-cells Conference Paper, J Ekeruche,M Clement,D Cole,K Ladell,E Edwards,John Miles,K Wynn,A Fuller,A Lissina,E Gostick, null |
| December 2010 | Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis Journal Paper, Mads Gabrielsen,Caroline Zetterström,Dai Wang,Katherine Beckham,Mikael Elofsson, Isaacs,Andrew Roe, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 (10) DOI: 10.1107/S1744309110039679 |
| December 2010 | Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen Journal Paper, M Driscoll,Kirsty J. McLean,Colin Levy,Nathalia Mast,Irina A Pikuleva,David Leys,Pierre Lafite,Stephen Rigby,Andrew Munro, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M110.164293 PMID: 20889498 |
| December 2010 | Cloning, purification and preliminary crystallographic analysis of cobalamin methyltransferases from Rhodobacter capsulatus Journal Paper, Arefeh Seyedarabi,M-T Hutchison,T To,E Deery,A Brindley,M Warren,Richard Pickersgill, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 (12) DOI: 10.1107/S1744309110042910 |
| December 2010 | Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding Journal Paper, Joel Kaar,Nicolas Basse,Andreas Christian Joerger,Elaine Stephens,Trevor Rutherford,Alan Fersht, PROTEIN SCIENCE 19 DOI: 10.1002/pro.507 |
| December 2010 | The crystal structure of the ubiquitin-like (UbL) domain of human homologue A of Rad23 (hHR23A) protein Journal Paper, Y. W. Chen,T. Tajima,S. Agrawal, Protein Engineering Design and Selection 24 DOI: 10.1093/protein/gzq084 |
| December 2010 | Structural basis of poly(ADP-ribose) recognition by the multizinc binding domain of checkpoint with forkhead-associated and RING Domains (CHFR) Journal Paper, Richard Bayliss,Jasmeen Oberoi,M Richards,N Brown, Journal of Biological Chemistry 285 PMID: 20880844 |
| November 2010 | The mechanism of retroviral integration from X-ray structures of its key intermediates. Journal Paper, Goedele Maertens,Stephen Hare,Peter Cherepanov, Nature 468 DOI: 10.1038/nature09517 |
| November 2010 | Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators. Journal Paper, Duo Lu,Sandy Fillet, Meng,Yilmaz Alguel,Patrick Kloppsteck, Bergeron, Krell, Gallegos, Ramos,Xiaodong Zhang, Genes Dev 24(22) DOI: 10.1101/gad.603510 |
| November 2010 | Crystallization and initial X-ray diffraction analysis of the tellurite-resistance S-adenosyl-L-methionine transferase protein TehB from Escherichia coli Journal Paper, Hassan Choudhury,Konstantinos Beis, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 DOI: 10.1107/S1744309110036043 |
| November 2010 | Insights into Association of the NuRD Complex with FOG-1 from the Crystal Structure of an RbAp48· FOG-1 Complex Journal Paper, Sara Lejon Dodd,Sock Yue Thong,Andal Murthy,Saad AlQarni,Nathalie Murzina,Gerd Blobel,Ernest Laue,Joel MacKay, Journal of Biological Chemistry 286 DOI: 10.1074/jbc.M110.195842 |
| November 2010 | Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization. Journal Paper, Richard Bayliss,C Mas-Droux,Rob van Montfort, J Med Chem. 53 PMID: 20936789 |
| November 2010 | Genetic and Structural Basis for Selection of a Ubiquitous T Cell Receptor Deployed in Epstein-Barr Virus Infection Journal Paper, John Miles,Anna Bulek,David Cole,Emma Gostick,Andrea Schauenburg,Garry Dolton,Vanessa Venturi,Miles Daveport,Mai Ping Tan,Scott Burrows,Linda Woolridge,David Price,Pierre Rizkallah,Andrew Sewell, PLOS Pathogens DOI: 10.1371/journal.ppat.1001198 |
| October 2010 | A redox switch in angiotensinogen modulates angiotensin release Journal Paper, Aiwu Zhou,Robin Carrell,Michael Murphy,Zhenquan Wei,Yahui Yan,Peter Stanley,Penelope Stein,Fiona Broughton Pipkin,Randy Read, Nature DOI: 10.1038/nature09505 |
| October 2010 | Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-dependent Carbohydrate Binding Modules Journal Paper, Montanier,James Flint,David Bolam,H. Xie,Ziyang Liu,A. Rogowski,D. P. Weiner,S. Ratnaparkhe,D. Nurizzo,S. M. Roberts,Johan Turkenburg,Gideon Davies,Harry Gilbert, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M110.142133 |
| October 2010 | Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1 Journal Paper, Zain Odho,Stacey Southall,Jon Wilson, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M110.159921 |
| October 2010 | Filament structure of bacterial tubulin homologue TubZ Journal Paper, Christopher Aylett,Qing Wang,Kate Michie,Linda Amos,Jan Lowe, Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.1010176107 |
| October 2010 | Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations Journal Paper, H. L. Schubert,Q. Zhai,V. Sandrin,D. M. Eckert,M. Garcia-Maya,L. Saul,W. I. Sundquist,Roberto Steiner,C. P. Hill, Proceedings of the National Academy of Sciences 107 DOI: 10.1073/pnas.1008206107 |
| October 2010 | Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: Comparison of native and antibiotic-bound forms Journal Paper, Sarah Sainsbury,Louise Bird,Vincenzo Rao,Sharon M Shepherd,Dave Stuart,William Hunter,Raymond Owens,Jingshan Ren, Journal of Molecular Biology DOI: 10.1016/j.jmb.2010.10.024 |
| September 2010 | Structural basis of semaphorin-plexin signalling Journal Paper, Bert Janssen,Ross Robinson,Francesc Pérez-Brangul,Christian Bell,Kevin Mitchell,Christian Siebold,Yvonne Jones, Nature DOI: 10.1038/nature09468 PMID: 20877282 |
| September 2010 | Structural Insights into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution Journal Paper, Ivan Campeotto,Amanda Bolt,Thomas Harman ,Caitriona Dennis,Chi Hung Trinh,Simon Phillips, Nelson,Arwen Pearson,Alan Berry, Journal of Molecular Biology DOI: 10.1016/j.jmb.2010.08.008 |
| September 2010 | Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'. Journal Paper, Klaus Fütterer,Sarah Batt,T Jabeen,Ajay Mishra,N Veerapen,K Krumbach,L Eggeling,G Besra, Journal of Biological Chemistry 285 PMID: 20843801 |
| September 2010 | The structural basis for catalysis and substrate specificity of a rhomboid protease Journal Paper, Kutti Vinothkumar,Kvido Strisovsky, Andreeva,Yonka Christova,Steven Verhelst, Freeman, The EMBO Journal DOI: 10.1038/emboj.2010.243 |
| September 2010 | The structure of the FnIII Tandem A77-A78 points to a periodically conserved architecture in the myosin-binding region of titin Journal Paper, Olga Mayans, Journal of Molecular Biology 401 PMID: 20542041 |
| September 2010 | Structures of the Human GTPase MMAA and Vitamin B12-dependent Methylmalonyl-CoA Mutase and Insight into Their Complex Formation Journal Paper, Sean Froese, Kochan, Muniz, Wu, Gileadi, Ugochukwu, Krysztofinska, Gravel, Oppermann, Yue, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M110.177717 |
| August 2010 | Visualizing the Metal-Binding Versatility of Copper Trafficking Sites Journal Paper, Adriana Badarau,Susan Firbank,Andrew McCarthy,Mark Banfield,Christopher Dennison, Biochemistry 49 DOI: 10.1021/bi101064w PMID: 20726513 |
| August 2010 | Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity. Journal Paper, Erik Chorell,Jerome Pinkner,Gilles Phan ,Sofie Edvinson,Floris Buelens,Han Remaut,Gabriel Waksman,Scott Hultgren,Fredrik Almqvist, J Med Chem. DOI: 10.1021/jm100470t |
| August 2010 | A highly unusual thioester bond in a pilus adhesin is required for efficient host cell interaction. Journal Paper, Jonathan Pointon,Wendy Smith,Gerhard Saalbach,Allister Crow,Michael Kehoe,Mark Banfield, Journal of Biological Chemistry DOI: 10.1074/jbc.M110.149385 PMID: 20729215 |
| August 2010 | Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-A from Rhodococcus ruber DSM 44541 Journal Paper, Martin Karabec,Andrzej Łyskowski,Katharina C. Tauber,Georg Steinkellner,Wolfgang Kroutil,Gideon Grogan,Karl Gruber, Chemical Communications 46 DOI: 10.1039/c0cc00929f |
| August 2010 | Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4. Journal Paper, P Filippakopoulos, Low, Sharpe, Uppenberg, Yao, Kuang, Savitsky, Lewis, Nicholson, Norton, Bullock, Journal of Molecular Biology 401 DOI: 10.1016/j.jmb.2010.06.017 |
| August 2010 | Crystal structure of MexZ, a key repressor responsible for antibiotic resistance in Pseudomonas aeruginosa Journal Paper, Yilmaz Alguel,Duo Lu,Nick Quade, Sauter,Xiaodong Zhang, Journal of Structural Biology 172(3) PMID: 20691272 |
| July 2010 | Structural Basis for Assembly of Hsp90-Sgt1-CHORD Protein Complexes: Implications for Chaperoning of NLR Innate Immunity Receptors Journal Paper, Minghao Zhang,Yasuhiro Kadota,Chrisostomos Prodromou,Ken Shirasu,Laurence H. Pearl, Molecular Cell 39(2) DOI: 10.1016/j.molcel.2010.05.010 |
| July 2010 | Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor. Journal Paper, Karlberg, Markova, Johansson, Hammarstrom, Schutz, Weigelt, Schuler, Journal of Medical Chemistry 53 PMID: 20565110 |
| July 2010 | Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster Journal Paper, Akif Mohd,Ioanna Ntai,Edward Sturrock,R Elwyn Isaac,Brian Bachmann,Ravi Acharya, Biochemical and Biophysical Research Communications DOI: 10.1016/j.bbrc.2010.06.113 |
| June 2010 | Crystal structures of Bacillus subtilis Lon protease. Journal Paper, R Duman,Jan Lowe, Journal of Molecular Biology 401 PMID: 20600124 |
| June 2010 | Specificity of Polysaccharide Use in Intestinal Bacteroides Species Determines Diet-Induced Microbiota Alterations Journal Paper, Erica Sonnenburg,Hongjun Zheng,Payal Joglekar,Steven Higginbottom,Susan Firbank,David Bolam,Justin Sonnenburg, Cell 141 (7) DOI: 10.1016/j.cell.2010.05.005 |
| June 2010 | Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases Journal Paper, Ivan Laponogov,Xiao-Su Pan,Dennis A. Veselkov,Katherine McAuley,L. Mark Fisher,Mark R. Sanderson,Art J. Lustig, PLoS ONE 5 DOI: 10.1371/journal.pone.0011338 |
| June 2010 | Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family. Journal Paper, J. Vevodova, Gamble, Kunze, Ariza, Dodson, Jones,Jon R Wilson, Structure 18 PMID: 20541512 |
| June 2010 | X-ray Crystal Structure and Time-Resolved Spectroscopy of the Blue Carotenoid Violerythrin Journal Paper, T Polivka, Frank, Enriquez, Niedzwiedzki, Liaaen-Jenson, Hemming,Madeleine Helliwell,John R Helliwell, Journal of Physical Chemistry B 114 DOI: 10.1021/jp101296a |
| May 2010 | High-Resolution Crystal Structures of Drosophila melanogaster Angiotensin-Converting Enzyme in Complex with Novel Inhibitors and Antihypertensive Drugs Journal Paper, Akif Mohd,Dimitris Georgiadis,Aman Mahajan,Vincent Dive,Edward Sturrock,R Elwyn Isaac,Ravi Acharya, Journal of Molecular Biology 400 DOI: doi:10.1016/j.jmb.2010.05.024 |
| May 2010 | Crystallization and initial X-ray diffraction analysis of a mannose-binding lectin from champedak Journal Paper, Mads Gabrielsen, Abdul-Rahman, Isaacs, Hashim, Cogdell, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 (5) DOI: 10.1107/S1744309110011760 |
| May 2010 | The structure of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei reveals a zinc binding site at the heart of the active site Journal Paper, Nicholas Harmer, Journal of Molecular Biology 400 DOI: doi:10.1016/j.jmb.2010.04.058 |
| May 2010 | Crystal structure of human RNA helicase A (DHX9): Structural basis for unselective nucleotide base binding in a DEAD-box variant protein Journal Paper, Patrick Schutz, Wahlberg, Karlberg,Martin Hammarstrom,Ruairi Collins, Flores,Herwig Schuler, Journal of Molecular Biology 400 (4) DOI: 10.1016/j.jmb.2010.05.046 |
| April 2010 | With phases: how two wrongs can sometimes make a right Journal Paper, Pietro Roversi,Steven Johnson,Susan Lea, Acta Crystallographica Section D Biological Crystallography 66 DOI: 10.1107/S0907444909048112 PMID: 20382995 |
| April 2010 | Structural homology between the C-terminal domain of the PapC usher and its plug. Journal Paper, Bradley Ford,Ana Toste Rego,Timothy Ragan,Jerome Pinkner,Karen Dodson,Paul Driscoll,Scott Hultgren,Gabriel Waksman, Journal of Bacteriology 10.1128/JB.01677-09 |
| April 2010 | Allosteric Mechanism of Pyruvate Kinase from Leishmania mexicana Uses a Rock and Lock Model Journal Paper, Hugh Morgan,Iain McNae,Matthew Nowicki,V. Hannaert,P. A. M. Michels,L. A. Fothergill-Gilmore,Malcolm Walkinshaw, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M109.079905 PMID: PMC2857090 |
| April 2010 | Domain cross-talk during effector binding to the multidrug binding TTGR regulator Journal Paper, Craig Daniels, Daddaoua,Duo Lu,Xiaodong Zhang, Ramos, Journal of Biological Chemistry 285(28) DOI: 10.1074/jbc.M110.113282 |
| April 2010 | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3 Journal Paper, Hazel Girwan,Colin Levy,P Williams,K Fisher,Myles Cheesman,Stephen Rigby,David Leys,Andrew Munro, Biochemical Journal 427 PMID: 20180779 |
| March 2010 | An analysis of substrate binding interactions in the heme peroxidase enzymes Journal Paper, Andrea Gumiero, Murphy,C Metcalfe,Peter Moody,Emma Raven, Arch Biochem Biophys in press DOI: doi:10.1016/j.abb.2010.02.015 PMID: 20206594 |
| March 2010 | Structural analysis of Thermus thermophilus HB27 mannosyl-3-phosphoglycerate synthase provides evidence for a second catalytic metal ion and new insight into the retaining mechanism of glycosyltransferases Journal Paper, Susana Goncalves,Nuno Borges,Ana Esteves,Bruno Victor,Claudio Soares,Helena Santos,Pedro Matias, Journal of Biological Chemistry DOI: doi:10.1074/jbc.M109.095976 |
| March 2010 | Defining the Molecular Basis of Bubr1 Kinetochore Interactions and Anaphase-Promoting Complex/Cyclosome (Apc/C)-Cdc20 Inhibition Journal Paper, S D'Arcy,O R Davies,T Blundell,V M Bolanos-Garcia, Journal of Biological Chemistry PMID: 20220147 |
| March 2010 | Chimeric microtubule disruptors Journal Paper, Matthew Leese,Fabrice Jourdan,Merial Kimberley,Geoffrey Masuyer,Nethaji Thiyagarajan,Chloe Stengel,Sandra Regis-Lydi, Foster,Simon Newman,Ravi Acharya,Eric Ferrandis,Atul Purohit,Michael Reed,Barry Potter, Chemical Communications 46 DOI: 10.1039/c002558e |
| March 2010 | Structural Basis of Substrate Binding in WsaF, a Rhamnosyltransferase from Geobacillus stearothermophilus Journal Paper, Kristin Steiner,Gregor Hagelueken,Paul Messner,Christina Schaffer,James Naismith, Journal of Molecular Biology 397 (2) DOI: 10.1016/j.jmb.2010.01.035 |
| February 2010 | Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex Journal Paper, S. Pernigo,A. Fukuzawa,M. Bertz,M. Holt,M. Rief,R. A. Steiner,M. Gautel, Proceedings of the National Academy of Sciences 107 DOI: 10.1073/pnas.0913736107 |
| February 2010 | Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites Journal Paper, Alexander I. Taylor,Brian J. Sutton,Rosaleen A. Calvert, Developmental & Comparative Immunology 34 DOI: 10.1016/j.dci.2009.08.012 PMID: 19733585 |
| February 2010 | Using structural information to change the phosphotransfer specificity of a two-component chemotaxis signalling complex. Journal Paper, Bell, Porter, Strawson,Dave Stuart, Armitage, PLoS Biology 8 DOI: 10.1371/journal.pbio.1000306 |
| February 2010 | Reengineering orthogonally selective riboswitches Journal Paper, N Dixon,J Duncan,T Geerlings, Dunstan,J McCarthy,David Leys,Jason Micklefield, Proceedings of the National Academy of Sciences 107 PMID: 20133756 |
| January 2010 | Structural basis for cofactor-independent dioxygenation of N-heteroaromatic compounds at the / -hydrolase fold Journal Paper, Roberto Steiner,H. J. Janssen,P. Roversi,A. J. Oakley,S. Fetzner, Proceedings of the National Academy of Sciences 107 DOI: 10.1073/pnas.0909033107 |
| January 2010 | The K5 Lyase KflA Combines a Viral Tail Spike Structure with a Bacterial Polysaccharide Lyase Mechanism Journal Paper, Thompson, Pourhossein, Waterhouse, Hudson,Marie Goldrick,Jeremy Derrick,Ian Roberts, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M110.127571 |
| January 2010 | Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches Journal Paper, Rose, Woon, Kingham, King, Mecinovic, Clifton, Ng, Talib-Hardy, Oppermann,Michael McDonough, Schofield, JOURNAL OF MEDICINAL CHEMISTRY 53 DOI: 10.1021/jm901680b |
| January 2010 | Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein Journal Paper, Hale,Philip Kerry, Jackson, Precious, Gray, Killip, Randall,Rupert Russell, Proceedings of the National Academy of Sciences 107 DOI: 10.1073/pnas.0910715107 |
| January 2010 | Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2 Journal Paper, Stephen Hilton,Sebastien Naud,John J. Caldwell,Kathy Boxall,Samantha Burns,Victoria E. Anderson,Laurent Antoni,Charlotte E. Allen,Laurence H. Pearl,Antony W. Oliver,G. Wynne Aherne,Michelle D. Garrett,Ian Collins, BIOORGANIC & MEDICINAL CHEMISTRY 18 DOI: 10.1016/j.bmc.2009.11.058 |
| January 2010 | Crystallization and preliminary X-ray analysis of a glucansucrase from the dental caries pathogen Streptococcus mutans Journal Paper, Keisuke Ito , Ito, Shimamura, Kawarasaki, Abe, Misaka, Kobayashi,So Iwata, Acta Crystallographica Section F Structural Biology and Crystallization Communications 66 DOI: 10.1107/S1744309110029714 |
| January 2010 | Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme Journal Paper, B Adalbjörnsson,H Toogood,A Fryszkowska, Pudney,Thomas Jowitt,David Leys,Nigel Scrutton, Chembiochem 11 PMID: 19943268 |
| January 2010 | Biophysical and X-ray Crystallographic Analysis of Mps1 Kinase Inhibitor Complexes Journal Paper, Matthew Chu, Lang,Leonard Chavas, Neres, Fedorova, Tabernero, Cherry, Williams, Douglas, Eyers, Biochemistry 49 DOI: 10.1021/bi901970c |
| January 2010 | Crystal Structures of the ATPase Domains of Four Human Hsp70 Isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B ', and HSPA5/BiP/GRP78 Journal Paper, Wisniewska,Tobias Karlberg, Lehtio, Johansson, Kotenyova, Moche,Herwig Schuler, PLoS One 5 DOI: 10.1371/journal.pone.0008625 |
| January 2010 | ATP-dependent MurE ligase in Mycobacterium tuberculosis: Biochemical and structural characterisation Journal Paper, Chandrakala Basavannacharya,Giles Robertson,Tulika Munshi,Sanjib Bhakta,Nicholas Keep, Tuberculosis 90 (1) DOI: 10.1016/j.tube.2009.10.007 |
| January 2010 | Structure of the Nucleoprotein Binding Domain of Mokola Virus Phosphoprotein Journal Paper, René Assenberg,Olivier Delmas,Jingshan Ren,Pierre-Olivier Vidalain,Anil Verma,Florence Larrous,Stephen Graham,Frédéric Tangy,Hervé Bourhy,Jonathan Grimes, Journal of Virology 84 (2) DOI: 10.1128/JVI.01520-09 |
| January 2010 | Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase Journal Paper, Wolthers,Colin Levy,Nigel Scrutton,David Leys, Journal of Biological Chemistry 285 DOI: 10.1074/jbc.M109.068908 |
| December 2009 | Investigations into Protein Crystallization in the Presence of a Strong Magnetic Field Journal Paper, Sachin Surade,Takashi Ochi,Daniel Nietlispach,Dima Chirgadze,Abel Moreno Carcamo, Crystal Growth & Design 10 (2) DOI: 10.1021/cg901109e |
| December 2009 | Structure of the outer membrane complex of a type IV secretion system. Journal Paper, Vidya Chandran,Remi Fronzes,Stephane Duquerroy,Nora Cronin,Jorge Navaza,Gabriel Waksman, Nature DOI: 10.1038/nature08588. |
| November 2009 | A Pocket on the Surface of the N-Terminal BRCT Domain of Mcph1 Is Required to Prevent Abnormal Chromosome Condensation Journal Paper, Mark Richards,Justin Leung,Junji Chen,Richard Bayliss,Mark Roe, Journal of Molecular Biology DOI: 10.1016/j.jmb.2009.11.029 |
| October 2009 | A cancer associated aurora-A mutant is mislocalised and misregulated due to loss of interaction with TPX2 Journal Paper, Rachel Bibby,Chan Tang,Amir Faisal,Konstantinos Drosopoulos,Stephen Lubbe,Richard Houlsdon,Spiros Linardopoulos,Richard Bayliss, Journal of Biological Chemistry DOI: 10.1074/jbc.M109.032722 |
| October 2009 | Characterization of a C-C hydrolase from Mycobacterium tuberuclosis involved in cholesterol metabolism Journal Paper, Nathan Lack,Katherine Yam,Ed Lowe,Geoff. P Horsman,Robin Owen,Edith Sim,Lindsay Eltis, Journal of Biological Chemistry DOI: 10.1074/jbc.M109.058081 |
| October 2009 | The structure of Mycobacterium tuberculosis CYP125: Molecular basis for cholesterol binding in a P450 needed for host infection Journal Paper, Kirsty J. McLean,Pierre Lafite,Myles Cheesman,Nathalia Mast,Irina A Pikuleva,Andrew Munro,Colin Levy,David Leys, Journal of Biological Chemistry DOI: 10.1074/jbc.M109.032706 |
| October 2009 | A fragment-based approach to probing adenosine recognition sites by using dynamic combinatorial chemistry. Journal Paper, Duncan.E Scott,Gwen J. Dawes,Michiyo Ando,Chris Abell,Alessio Ciulli, Chembiochem 10 (17) DOI: 10.1002/cbic.200900537 PMID: 19827080 |
| September 2009 | Molecular Architecture of the Mos1 Paired-End Complex: The Structural Basis of DNA Transposition in a Eukaryote Journal Paper, Julia Richardson,Sean D. Colloms,David J. Finnegan,Malcolm Walkinshaw, Cell 138 DOI: 10.1016/j.cell.2009.07.012 PMID: 19766564 |
| August 2009 | The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation Journal Paper, Jody Winter,Panayiotis Christofi,Shaun Morroll,Karen Bunting, BMC Structural Biology 9 (55) DOI: 10.1186/1472-6807-9-55 |
| July 2009 | Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core Journal Paper, Khoo, Freund, Fersht,Andreas Christian Joerger, Protein Eng Des Sel 22 (7) DOI: 10.1093/protein/gzp018 |
| June 2009 | Characterisation of Bombyx mori Odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components Journal Paper, Zhou,Giles Robertson, He, Dufour, Hooper, Pickett, Field,Nicholas Keep, Journal of Molecular Biology 389 (3) DOI: 10.1111/j.1570-7458.2006.00400.x PMID: 19371749 |
| June 2009 | Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the SH3C Domain of Grb2 Journal Paper, Maria Harkiolaki,Theodora Tsirka,Marc Lewitzky,Philip Simister,Dhira Joshi,Louise Bird, Jones,Nicola O'Reilly,Stephen Feller, Structure 17 (6) DOI: 10.1016/j.str.2009.03.017 |
| May 2009 | Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A Journal Paper, Grazyna Kochan,Ewa Pilka,Frank von Delft,Udo Oppermann,Wyatt Yue, Journal of Molecular Biology |
| May 2009 | Crystallization and preliminary X-ray analysis of a bifunctional catalase-phenol oxidase from Scytalidium thermophilum Journal Paper, Arwen Pearson,Simon Phillips,Michael McPherson,Didem Kocabas,U Bakir,Z Bakir,Chi Hung Trinh, Acta Crystallographica Section F Structural Biology and Crystallization Communications 65 DOI: 10.1107/S1744309109012007 |
| May 2009 | Crystal Structures of Cif from Bacterial Pathogens Photorhabdus luminescens and Burkholderia pseudomallei Journal Paper, Jubelin,Carolina Varela Chavez,Jean-Michel Escoubas,Eric Oswald,Mark Banfield,Allister Crow,Paul Race, PLoS One DOI: 10.1371/journal.pone.0005582 |
| May 2009 | Structure of the human Nac1 POZ domain Journal Paper, Mark Stead,Stephen Carr,Stephanie Wright, Acta Crystallographica Section F Structural Biology and Crystallization Communications 65 DOI: 10.1107/S1744309109012214 |
| May 2009 | Structural insight into the quinoloneDNA cleavage complex of type IIA topoisomerases Journal Paper, Ivan Laponogov,Maninder K Sohi,Dennis A Veselkov,Xiao-Su Pan,Ritica Sawhney,Andrew W Thompson,Katherine McAuley,L Mark Fisher,Mark R Sanderson, Nature Structural & Molecular Biology 16 DOI: 10.1038/nsmb.1604 |
| April 2009 | Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design Journal Paper, Bibek Gooptu, Miranda, Nobelis, Mallya, Purkiss, Brown, Summers, Phillips, Lomas, Barrett, Journal of Molecular Biology 387 |
| April 2009 | Distinct and essential morphogenic functions for wall- and lipo-teichoic acids in Bacillus subtilis Journal Paper, Schirner, Errington,Rick Lewis,Jon Marles-Wright, The EMBO Journal 28 (7) DOI: 10.1038/emboj.2009.25 |
| March 2009 | Structures of Leishmania major orthologues of macrophage migration inhibitory factor Journal Paper, Julia Richardson,Lesley S. Morrison,Nicholas D. Bland,Sandra Bruce,Graham H. Coombs,Jeremy C. Mottram,Malcolm D. Walkinshaw, Biochemical and Biophysical Research Communications 380 DOI: 10.1016/j.bbrc.2009.01.030 PMID: 19187777 |
| March 2009 | Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity Journal Paper, C Tron,Iain McNae,M Nutley,D Clarke,A Cooper,Malcolm Walkinshaw,R Baxter,Dominic Campopiano, Journal of Molecular Biology 387(1) DOI: 10.1016/j.jmb.2008.12.086 PMID: 19385043 |
| March 2009 | Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function Journal Paper, C. Montanier,Alicia Lammerts Van Bueren,C. Dumon,James Flint,Márcia Correia,J. A. Prates,Susan Firbank,Rick Lewis,G. G. Grondin,M. G. Ghinet,T. M. Gloster,C. Herve,J. P. Knox,B. G. Talbot,Johan Turkenburg,J. Kerovuo,R. Brzezinski,C. M. G. A. Fontes,G. J. Davies,A. B. Boraston, Proceedings of the National Academy of Sciences 106 DOI: 10.1073/pnas.0808972106 |
| March 2009 | Metal-binding loop length and not sequence dictates structure Journal Paper, Sako,Chan Li,Isabelle Salard,Andrew Thompson,Christopher Dennison,Mark Banfield, Proceedings of the National Academy of Sciences 106 (14) DOI: 10.1073/pnas.0811324106 |
| February 2009 | Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates Journal Paper, Muriel C Schneider,Beverly E Prosser,Joseph J.E. Caesar,Elisabeth Kugelberg, Li, Zhang,Sadik Quoraishi,Janet E. Lovett,Janet E Deane,Robert B Sim,Pietro Roversi,Steven Johnson,Christina Tang,Susan Lea, Nature 458 DOI: 10.1038/nature07769 |
| February 2009 | Crystal Structure of a Catalytically Active, Non-Toxic Endopeptidase Derivative of Clostridium Botulinum Toxin A Journal Paper, Geoffrey Masuyer,Nethaji Thiyagarajan,Peter James,Philip Marks,John Chaddock,Ravi Acharya, Biochemical and Biophysical Research Communications 381 (1) DOI: 10.1016/j.bbrc.2009.02.003 |
| February 2009 | Structural basis of the radicicol resistance displayed by a fungal hsp90. Journal Paper, Prodromou,James Nuttall, Millson,Tiow-Suan Sim,Doreen Tan,Paul Workman,Laurence H Pearl,Peter W. Piper,Mark Roe, ACS Chemical Biology 4 (4) DOI: 10.1021/cb9000316 |
| February 2009 | Insights Into the Conformational Variability and Regulation of Human Nek2 Kinase. Journal Paper, Isaac Westwood,Donna-Marie Cheary,Joanne Baxter,Mark Richards,Rob van Montfort,Andrew Fry,Richard Bayliss, Journal of Molecular Biology 386 (2) DOI: 10.1016/j.jmb.2008.12.033 |
| January 2009 | The Crystal Structure of an Avian IgY-Fc Fragment Reveals Conservation with both Mammalian IgG and IgE Journal Paper, Alexander I. Taylor,Stella M. Fabiane,Brian J. Sutton,Rosaleen A. Calvert, Biochemistry 48 DOI: 10.1021/bi8019993 PMID: 19115948 |
| January 2009 | Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks Journal Paper, Stacey M Southall,Poon-Sheng Wong,Zain Odho,Jon R Wilson,Mark Roe, Molecular Cell 33 DOI: 10.1016/j.molcel.2008.12.029 |
| January 2009 | Crystal Structure of Streptococcus pyogenes Sortase A: Implications for Sortase mechanism Journal Paper, Paul Race, Bentley,Jeff Melvin,Allister Crow,Richard Hughes,Wendy Smith,Richard Sessions,Michael Kehoe,Dewey McCafferty,Mark Banfield, Journal of Biological Chemistry 284 (11) DOI: 10.1074/jbc.M805406200 |
| December 2008 | Exploring the mechanism of tryptophan 2,3-dioxygenase Journal Paper, Sarah J. Thackray,Christopher G. Mowat,Stephen K. Chapman, Biochemical Society Transactions 36 DOI: 10.1042/BST0361120 PMID: 19021508 |
| November 2008 | Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL Journal Paper, Stephane Mouilleron,Sebastian Guettler,Carola Langer,Richard Treisman,Neil McDonald, The EMBO Journal 27 DOI: 10.1038/emboj.2008.235 |
| November 2008 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Journal Paper, Rupert Russell,Philip Kerry,David Stevens,David Steinhauer,Stephen Martin,Steven Gamblin,John Skehel, Proceedings of the National Academy of Sciences 105 DOI: 10.1073/pnas.0807142105 |
| November 2008 | A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex Journal Paper, Bernie Kelly,Airlie McCoy,Kira Spate,Sharon Miller,Stefan Honing,David Owen,Phil Evans, Nature DOI: 10.1038/nature07422 |
| November 2008 | Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans. Journal Paper, Chi Hung Trinh, Hunter, Stewart, Phillips, Hunter, Acta Crystallographica Section F Structural Biology and Crystallization Communications 64(12) DOI: 10.1107/S1744309108037056 |
| October 2008 | The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines. Journal Paper, Kadlec, Loureiro, Jones,Nicola Abrescia,Dave Stuart, Nature Structural & Molecular Biology 10 PMID: 18776902 |
| October 2008 | Molecular Architecture of the "Stressosome" a Signal Integration and Transduction Hub Journal Paper, Jon Marles-Wright,Tim Grant,Olivier Delumeau,Gijs van Duinen,Susan Firbank,Peter J Lewis,James W Murray,Joseph A Newman,Maureen Quin,Paul Race, Science 322 DOI: 10.1126/science.1159572 |
| September 2008 | Structural insights into mechanism and specificity of O-GlcNAc transferase Journal Paper, Andrew Clarke,Ramon Hurtado-Guerrero,Shalini Pathak,Alexander W Schüttelkopf,Vladimir Borodkin,Sharon M Shepherd,Ade F M Ibrahim,Daan M F van Aalten, The EMBO Journal 27 DOI: 1038/emboj.2008.186 |
| August 2008 | Structural and Functional Analysis of the Crb2-Brct2 Domain Reveals Distinct Roles in Checkpoint Signaling and DNA Damage Repair Journal Paper, Mairi Kilkenny,Andrew Dore, Nestoras, Ho, Watts, Pearl,Mark Roe, Genes and Development 22 DOI: 10.1101/gad.472808 |
| August 2008 | Macromolecular crystallography at Diamond Light Souce: Automation and pathogenic sample environment Journal Paper, Dave Hall,Alun Ashton,Jose Brandao-Neto,David Butler,Liz Duke,Gwyndaf Evans,Ralf Flaig, Foster,Paul Gibbons,Mic Harding,Mike Latchem,Karl Levik,Katherine McAuley,James O'Hea,Geoff Preece,James Sandy, Waterman, Williams,Richard Woolliscroft,Thomas Sorensen, Acta Crystallographica Section A Foundations of Crystallography 64 |
| August 2008 | Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125. Journal Paper, Matthew Chu,Leonard Chavas, Douglas, Eyers, Tabernero, Journal of Biological Chemistry 283 (31) PMID: 18480048 |
| August 2008 | Experience from operation and commissioning of the Phase 1 MX beamlines at Diamond Light Source Conference Paper, Ralf Flaig,Alun Ashton,Jose Brandao-Neto,Liz Duke,Gwyndaf Evans, Foster,Paul Gibbons,Arno Grant,Dave Hall,Mike Latchem,Karl Levik,Katherine McAuley,James O'Hea,Geoff Preece,James Sandy,Thomas Sorensen,David Waterman,Richard Woolliscroft, null |
| August 2008 | Vaccinia Virus Proteins A52 and B14 Share a Bcl-2 Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis Journal Paper, Mohammad Bahar, Cooray, Chen,Daniel Whalen,Nicola Abrescia,David Alderton,Raymond Owens,Geoffrey Smith,Stephen Graham,Dave Stuart, PLOS Pathogens 4 (8) DOI: 10.1371/journal.ppat.1000128 |
| June 2008 | The FACT Spt16 'peptidase' domain is a histone H3'H4 binding module Journal Paper, Tobias Stuwe,Michael Hothorn,Erwan Lejeune,Vladimir Rybin,Miriam Bortfeld,Klaus Scheffzek,Andreas Ladurner, Proceedings of the National Academy of Sciences 105 no 26 DOI: 10.1073/pnas.0712293105 |
| May 2008 | Structure of the DNA Repair Helicase XPD Journal Paper, Huntang Liu,Jana Rudolf,Kenneth Johnson,Stephen McMahon,Muse Oke,Lester Carter,Anne-Marrie McRobbie,Sara E Brown,Malcolm White,James Naismith, Cell 133, Issue 5 DOI: 10.1016/j.cell.2008.04.029 |
| May 2008 | Combinatorial histone H3 tail decoding by the Pygo-BCL9 complex. Journal Paper, Marc Fiedler,Maria Sanchez Barrena, Nekrasov, Mieszczanek, Rybin, Muller,Phil Evans,Mariann Bienz, Molecular Cell 30 (4) PMID: 18498752 |
| April 2008 | Structures of the Shigella flexneri type 3 secretion system protein MxiC reveal conformational variability amongst homologues Journal Paper, Pietro Roversi, King,Steven Johnson,Susan Lea,Janet E Deane, Journal of Molecular Biology 377 (4) PMID: 18304577 |
| March 2008 | Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex Journal Paper, Li,Ty Adams, Nangalia, Esmon,Jim Huntington, Proceedings of the National Academy of Sciences 105 (12) DOI: 10.1073/pnas.0711055105 |
| March 2008 | Crystallization and preliminary X-ray analysis of RsbS from Moorella thermoacetica at 2.5 A resolution Journal Paper, Susan Firbank,Rick Lewis,Jon Marles-Wright,Joseph A Newman,Maureen Quin, Acta Crystallographica Section F Structural Biology and Crystallization Communications 64 (Pt 3) PMID: 18323607 |
| January 2008 | Structure of the topoisomerase IV from S. pneumoniae with a DNA target and quinolone drug Poster, Ivan Laponogov,Maninder Sohi,Dennis Veselkov, Pan, Sawhney, Thompson,Mark Fisher,Mark Sanderson, Acta Crystallographica Section A Foundations of Crystallography 64 |
| August 2007 | Commissioning Progress at Diamond Light Source. Conference Paper, Ralf Flaig, null |
| May 2007 | Crystallization and preliminary X-ray analysis of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase from Arthrobacter nitroguajacolicus Ru61a: a cofactor-devoid dioxygenase of the alpha/beta hydrolase-fold superfamily Journal Paper, Roberto Steiner,U Frerichs-Deeken,Susan Fetzner, Acta Crystallographica Section F Structural Biology and Crystallization Communications 63 PMID: 17565176 |