The HC1b is a device developed by the Instrumentation Group at the EMBL outstation at Grenoble. It has been thoroughly tested at the ESRF at ID14-2 and BM14. The device is now at Diamond and available at the I03, I04 and I24 beamlines. In addition there is a laboratory facility to use the HC1 before your beamtime. These pages are designed to provide detailed information of how this device may be useful for you.
Please browse these pages or e-mail DLSHC1REQUESTS@diamond.ac.uk if you would like more information on technical aspects of the experiments and on how to request its use.
The HC1 can be swapped at the click of a button and the experiment can be controlled using GDA scripts.
Wheeler, M. J., S. Russi, et al. (2012). "Measurement of the equilibrium relative humidity for common precipitant concentrations: facilitating controlled dehydration experiments." Acta Crystallogr Sect F Struct Biol Cryst Commun 68(1): 111-114.
Russo Krauss, I., F. Sica, et al. (2012). "Increasing the X-ray Diffraction Power of Protein Crystals by Dehydration: The Case of Bovine Serum Albumin and a Survey of Literature Data." Int J Mol Sci 13(3): 3782-3800.
Bowler, M. W., M. G. Montgomery, et al. (2006). "Reproducible improvements in order and diffraction limit of crystals of bovine mitochondrial F(1)-ATPase by controlled dehydration." Acta Crystallogr D Biol Crystallogr 62(9): 991-995.
Kiefersauer, R., M. E. Than, et al. (2000). "A novel free-mounting system for protein crystals: transformation and improvement of diffraction power by accurately controlled humidity changes." Journal of Applied Crystallography 33(5): 1223-1230.
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