Charlotte Edwards-Gayle

Charlotte received her BSc degree in Biochemistry at King's College London University in 2016. She completed her PhD in Chemistry at the University of Reading joint with Diamond Light Source in 2020 focused on self-assembly and bioactivity of peptides and peptide conjugates. During her PhD she worked on designing the multi-purpose sample 'MPS' cell, enabling viscous liquids and non-solution samples to be measured on B21, expanding the user base on B21. 

 Currently Charlotte is the PDRA on B21. Her research is currently focused on peptide based antimicrobials, membrane interaction studies, soft condensed matter data modelling and sample envirnonment development. She also has experience with lipid phases, polymer systems, nanoparticles and drug delivery systems. 

Madeira, Paula Corsini; Wang, Sunjun; Fenn, Katherine; Sagar, Amin; Sirovica, Slobadan; Cleaver, Leanne; Edwards-Gayle, Charlotte; Mastroianni, Giulia; Dorgan, Benjamin James; Sewell, Lee; Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation npj Biofilms and Microbiomes, 2022

Edwards-Gayle, Charlotte Jennifer Chante; Khunti, Nikul; Hamley, Ian W; Inoue, Katsuaki; Cowieson, Nathan; Rambo, Robert;  Design of a multipurpose sample cell holder for the Diamond Light Source high‐throughput SAXS beamline B21, Journal of synchrotron radiation, 28, 1, 318-321, 2021

Egan, Jacquelyn G; Brodie, Glen; McDowall, Daniel; Smith, Andrew J; Edwards-Gayle, Charlotte JC; Draper, Emily R; Impact of subtle change in branched amino acid on the assembly and properties of perylene bisimides hydrogels, Materials Advances, 2, 15, 5248-5253, 2021

Corrêa, Raissa Lohanna Gomes Quintino; Dos Santos, Renan; Albuquerque, Lindomar José Calumby; de Araujo, Gabriel Lima Barros; Edwards-Gayle, Charlotte Jennifer Chante; Ferreira, Fabio Furlan; Costa, Fanny Nascimento; Ciprofibrate-Loaded Nanoparticles Prepared by Nanoprecipitation: Synthesis, Characterization, and Drug Release Polymers, 13, 18, 3158, 2021

McDowall, Daniel; Walker, Matthew; Vassalli, Massimo; Cantini, Marco; Khunti, Nikul; Edwards-Gayle, Charlotte Jennifer Chante; Cowieson, Nathan; Adams, Dave J; Controlling the formation and alignment of low molecular weight gel ‘noodles’      Chemical Communications, 57, 70, 8782-8785, 2021

Pelin, Juliane NBD; Gerbelli, Barbara B; Edwards-Gayle, Charlotte JC; Aguilar, Andrea M; Castelletto, Valeria; Hamley, Ian W; Alves, Wendel A; Amyloid peptide mixtures: self-assembly, hydrogelation, nematic ordering, and catalysts in aldol reactions, Langmuir, 36, 11, 2767-2774, 2020

Castelletto, Valeria; Edwards-Gayle, Charlotte JC; Hamley, Ian W; Barrett, Glyn; Seitsonen, Jani; Ruokolainen, Janne; De Mello, Lucas Rodrigues; Da Silva, Emerson Rodrigo; Model self-assembling arginine-based tripeptides show selective activity against Pseudomonas bacteria  , Chemical Communications, 56, 4, 615-618, 2020

Cowieson, Nathan P; Edwards-Gayle, Charlotte JC; Inoue, Katsuaki; Khunti, Nikul S; Doutch, James; Williams, Eugene; Daniels, Steven; Preece, Geoff; Krumpa, Nicholas A; Sutter, John P;                Beamline B21: high-throughput small-angle X-ray scattering at Diamond Light Source       Journal of Synchrotron Radiation, 27, 5, 1438-1446, 2020

Castelletto, Valeria; Seitsonen, Jani; Ruokolainen, Janne; Piras, Cristian; Cramer, Rainer; Edwards-Gayle, Charlotte JC; Hamley, Ian W; Peptide nanotubes self-assembled from leucine-rich alpha helical surfactant-like peptides, Chemical Communications, 56, 80, 11977-11980, 2020

Pelin, Juliane NBD; Edwards-Gayle, Charlotte JC; Martinho, Herculano; Gerbelli, Barbara B; Castelletto, Valeria; Hamley, Ian W; Alves, Wendel A; Self-assembled gold nanoparticles and amphiphile peptides: a colorimetric probe for copper (ii) ion detection, Dalton Transactions, 49, 45, 16226-16237, 2020

Pelin, Juliane NBD; Edwards-Gayle, Charlotte JC; Castelletto, Valeria; Aguilar, Andrea M; Alves, Wendel A; Seitsonen, Jani; Ruokolainen, Janne; Hamley, Ian W;                Self-Assembly, Nematic phase formation, and organocatalytic behavior of a proline-functionalized lipopeptide               ACS applied materials & interfaces, 12, 12, 13671-13679, 2020

Edwards-Gayle, Charlotte JC; Barrett, Glyn; Roy, Shyamali; Castelletto, Valeria; Seitsonen, Jani; Ruokolainen, Janne; Hamley, Ian W; Selective antibacterial activity and lipid membrane interactions of arginine-rich amphiphilic peptides, ACS applied bio materials, 3, 2, 1165-1175,2020

Radvar, Elham; Shi, Yejiao; Grasso, Salvatore; Edwards-Gayle, Charlotte JC; Liu, Xitong; Mauter, Meagan S; Castelletto, Valeria; Hamley, Ian W; Reece, Michael J; S. Azevedo, Helena; Magnetic field-induced alignment of nanofibrous supramolecular membranes: a molecular design approach to create tissue-like biomaterials, ACS applied materials & interfaces, 12, 20, 22661-22672   2020

Mondal, Biplab; Bairagi, Dipayan; Nandi, Nibedita; Hansda, Biswanath; Das, Krishna Sundar; Edwards-Gayle, Charlotte JC; Castelletto, Valeria; Hamley, Ian W; Banerjee, Arindam;                Peptide-based gel in environmental remediation: removal of toxic organic dyes and hazardous Pb2+ and Cd2+ ions from wastewater and oil spill recovery, Langmuir, 36, 43, 12942-12953, 2020

Pelin, Juliane NBD; Edwards-Gayle, Charlotte JC; Aguilar, Andrea M; Kaur, Amanpreet; Hamley, Ian W; Alves, Wendel A;           Polymorphism of asymmetric catalysts based on amphiphilic lipopeptides in solution, Soft Matter, 16, 19, 4615-4624, 2020

Edwards-Gayle, Charlotte JC; Castelletto, Valeria; Hamley, Ian W; Barrett, Glyn; Greco, Francesca; Hermida-Merino, Daniel; Rambo, Robert P; Seitsonen, Jani; Ruokolainen, Janne;        Self-assembly, antimicrobial activity, and membrane interactions of arginine-capped peptide bola-amphiphiles            ACS applied bio materials, 2, 5, 2208-2218, 2019

Castelletto, Valeria; Edwards-Gayle, Charlotte JC; Greco, Francesca; Hamley, Ian W; Seitsonen, Jani; Ruokolainen, Janne; Self-Assembly, tunable hydrogel properties, and selective anti-cancer activity of a carnosine-derived lipidated peptide, ACS applied materials & interfaces, 11, 37,33573-33580, 2019

Hutchinson, Jessica A; Hamley, Ian W; Edwards-Gayle, Charlotte JC; Castelletto, Valeria; Piras, Cristian; Cramer, Rainer; Kowalczyk, Radoslaw; Seitsonen, Jani; Ruokolainen, Janne; Rambo, Robert P; Melanin production by tyrosinase activity on a tyrosine-rich peptide fragment and pH-dependent self-assembly of its lipidated analogue,Organic & Biomolecular Chemistry, 17, 18, 4543-4553, 2019

Castelletto, Valeria; Edwards-Gayle, Charlotte JC; Hamley, Ian W; Pelin, Juliane NBD; Alves, Wendel A; Aguilar, Andrea M; Seitsonen, Jani; Ruokolainen, Janne; Self-assembly of a catalytically active lipopeptide and its incorporation into cubosomes, ACS applied bio materials, 2, 8, 3639-3647, 2019

Castelletto, Valeria; Edwards-Gayle, Charlotte JC; Hamley, Ian W; Barrett, Glyn; Seitsonen, Jani; Ruokolainen, Janne;   Peptide-stabilized emulsions and gels from an arginine-rich surfactant-like peptide with antimicrobial activity, ACS applied materials & interfaces, 11, 10, 9893-9903, 2019

Khalily, Mohammad Aref; Usta, Hakan; Ozdemir, Mehmet; Bakan, Gokhan; Dikecoglu, F Begum; Edwards-Gayle, Charlotte; Hutchinson, Jessica A; Hamley, Ian W; Dana, Aykutlu; Guler, Mustafa O; The design and fabrication of supramolecular semiconductor nanowires formed by benzothienobenzothiophene (BTBT)-conjugated peptides, Nanoscale, 10, 21, 9987-9995, 2018

Castelletto, Valeria; Barnes, Ruth H; Karatzas, Kimon-Andreas; Edwards-Gayle, Charlotte JC; Greco, Francesca; Hamley, Ian W; Seitsonen, Jani; Ruokolainen, Janne;        Restructuring of lipid membranes by an arginine-capped peptide bolaamphiphile, Langmuir, 35, 5, 1302-1311, 2018

Castelletto, Valeria; Barnes, Ruth H; Karatzas, Kimon-Andreas; Edwards-Gayle, Charlotte JC; Greco, Francesca; Hamley, Ian W; Rambo, Robert; Seitsonen, Jani; Ruokolainen, Janne;                Arginine-containing surfactant-like peptides: Interaction with lipid membranes and antimicrobial activity, Biomacromolecules, 19, 7, 2782-2794, 2018

Edwards-Gayle, Charlotte JC; Greco, Francesca; Hamley, Ian W; Rambo, Robert P; Reza, Mehedi; Ruokolainen, Janne; Skoulas, Dimitrios; Iatrou, Hermis;                Self-assembly of telechelic tyrosine end-capped PEO star polymers in aqueous solution, Biomacromolecules, 19, 1, 167-177, 2018

Edwards-Gayle, Charlotte JC; Hamley, Ian W; Self-assembly of bioactive peptides, peptide conjugates, and peptide mimetic materials, Organic & biomolecular chemistry, 15, 28, 5867-5876, 2017

Arslan, Elif; Hatip Koc, Meryem; Uysal, Ozge; Dikecoglu, Begum; Topal, Ahmet E; Garifullin, Ruslan; Ozkan, Alper D; Dana, Aykutlu; Hermida-Merino, Daniel; Castelletto, Valeria;  Supramolecular peptide nanofiber morphology affects mechanotransduction of stem cells, Biomacromolecules, 18, 10, 3114-3130, 2017

Guler, M; Dana, A; Topal, A; Hamley, I; Koc, Hatip; Garifullin, R; Tekinay, A; Baday, S; Arslan, E; Castelletto, V;                Supramolecular Peptide Nanofiber Morphology Affects Mechanotransduction of Stem Cells