Speeding up the drug discovery process has taken a while to achieve, however Fragment Screening promises to do exactly this. In this article Frank von Delft tells us how Diamond's XChem facility delivers a fast, streamlined process with low overheads for its users.
On 18th October, our XChem facility on beamline I04-1 diffracted its 100,000th crystal dataset since 2014 - just 1yr for the 2nd 50k! Find out how this technique can advance your research.
The XChem facility @DiamondLightSou provides key information for structure-based drug design. In a recent study we look at how to generate crystals for successful Fragment Screening: Find out more.
Access to the fragment soaking platform and automated data collection at come Diamond has added a further element on top of our diverse internal portfolio of streamlined biochemical, high-content and biophysical screening capabilities at Evotec. Operating through the facility infrastructure and with supporting expertise of Diamond staff we have added significant value to several collaborations this year alone. Most importantly we are delivering information-rich structures to our clients and internal medicinal chemistry teams in a time and cost-effective manner at a critical early phase in the drug discovery pathway.
Dr Paul McEwan, Evotec
Meet the team
Meet the XChem team, who can support all of your fragment screening needs.
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
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