Watch our video featuring Nobel Prize winner, Richard Henderson to see how this world-class facility is impacting science: https://youtu.be/5DEAgrHVZEA
Speeding up the drug discovery process has taken a while to achieve, however Fragment Screening promises to do exactly this. In this article Frank von Delft tells us how Diamond's XChem facility delivers a fast, streamlined process with low overheads for its users.
Using Macromolecular Crystallography (MX), scientists at Diamond worked with Heptares Therapeutics to target G-protein-couple receptors (GPCRs) to develop new medicines to target areas such as cancer, central nervous system disorders,diabetes, obesity and pain. Find out more.
On 18th October, our XChem facility on beamline I04-1 diffracted its 100,000th crystal dataset since 2014 - just 1yr for the 2nd 50k! Find out how this technique can advance your research.
A recent article in Nature highlights the growth of cryo-EM for drug discovery and the importance of shared facilities such as eBIC at Diamond in widening access to industry.
The XChem facility @DiamondLightSou provides key information for structure-based drug design. In a recent study we look at how to generate crystals for successful Fragment Screening: Find out more.
Using VMXi at Diamond scientists have achieved new insights into an antibody directed against Dengue Fever. Find out more.
Heptares Therapeutics explain how grid scan techniques on Diamond's MX beamlines is optimising the conditions for GPCR crystallography, maximising the rate at which protein crystals can be scanned and the quality of the data collected. Read our case study.
Meet the team
Meet the Life Science team, who can support all of your biological structure needs.
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
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