___________________________________
Industrial Liaison Group:
Tel: +44 (0) 1235 778797
E-mail: [email protected]
.jpg)
Using a previously identified clinical candidate, GSK used Macromolecular Crystallography (MX) to investigate the potential activity of a highly selective compound, with enhanced potency and selectivity.
The aim of the study was to target a key signalling molecule and treat a range of inflammatory conditions such as asthma and chronic obstructive pulmonary disease. The resulting inhibitor would be bioavailable, effective at low doses (preventing toxicity) and would be suitable for oral delivery. Find out what they discovered.
Image: NIAID, CC BY 2.0 <https://creativecommons.org/licenses/by/2.0>, via Wikimedia Commons
Diamond Light Source is the UK's national synchrotron science facility, located at the Harwell Science and Innovation Campus in Oxfordshire.
Copyright © 2022 Diamond Light Source
Diamond Light Source Ltd
Diamond House
Harwell Science & Innovation Campus
Didcot
Oxfordshire
OX11 0DE
Diamond Light Source® and the Diamond logo are registered trademarks of Diamond Light Source Ltd
Registered in England and Wales at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom. Company number: 4375679. VAT number: 287 461 957. Economic Operators Registration and Identification (EORI) number: GB287461957003.
Industrial Liaison Office
