Annual Review 2024-2025

Beamline Main Capabilities Energy / Wavelength Range B23 - Circular Dichroism Circular Dichroism (CD) Module A: 125-500nm for CD Imaging at 50 µm spatial resolution, and for 96-cell high throughput CD (HTCD). Module B: 180-700nm for MMP at 50 µm spatial resolution. I24 - Microfocus and Serial MX MX, MAD, Serial Crystallography, high energy MX 7 - 30.0 keV B24 - Cryo Transmission X-ray Microscopy (TXM) Cryo Structured Illumination microscope (CryoSIM) 3D cryo super resolution fluorescence microscopy /correlative microscopy 405, 488, 561, 647 nm A N N U A L R E V I E W 2 0 2 4 / 2 5 54 I N S T R UM E N T D E V E L O P M E N T A N D T E C H N I C A L S UMM A RY Beamline Main Capabilities Energy / Wavelength Range K04 - ultra-HT MX for XChem Automated, integrated, ultra-high throughput crystal preparation and MX for accelerated chemical biology 10 – 27 keV K14 - SWIFT X-ray Absorption Spectroscopy (Quick-EXAFS), X-ray fluorescence (XRF) and X-ray diffraction (XRD) mapping and tomography 4-34 keV I17 – CSXID Ptychography, Tomography, Scanning Transmission X-ray Microscopy (STXM), X-ray Absorption Spectroscopy (XAS) and X-ray Magnetic Circular and Linear Dichroism (XMCD/XMLD) 250 eV – 2000 eV New beamlines in development for Diamond-II