Tel: +44 (0) 1235 56 7480
E-mail: EBICadmin@diamond.ac.uk
Peijun Zhang
Tel: +44 (0) 1235 77 8878
E-mail: peijun.zhang@diamond.ac.uk
Daniel Clare
Tel: +44 (0) 1235 56 7501
E-mail: daniel.clare@diamond.ac.uk
Yuriy Chaban
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E-mail: yuriy.chaban@diamond.ac.uk
Karen Davies
Tel: +44 (0) 1235 77 8057
E-mail: karen.davies@diamond.ac.uk
Tel: +44 (0) 1235 56 7480
E-mail: EBICadmin@diamond.ac.uk
Email: martin.walsh@diamond.ac.uk
Tel: +44 (0)1235 778518
The Titan Krios is a fully automated cryo-electron microscope from Thermo Fisher Scientific, designed for rapid, stable, high-resolution data collection on frozen-hydrated samples.
Four Titan Krios microscopes are available at eBIC for academic users. Krios I, II, & IV are equipped with the latest generation Ametek-Gatan Bio-quantum-K3 detectors and energy filter. Krios III is equipped with the Thermo Fisher Scientific Falcon 4i detector & Selectris X energy filter.
Cryogenic electron microscopy (cryo-EM) and cryogenic electron tomography (cryo-ET) data can be collected automatically on all four Krios microscope.
Thermo Fisher Scientific's EPU and Tomography software, with aberration-free image shift data collection (AFIS), are primarily used for single particle analysis (SPA) and tomographic data collection at eBIC, respectively. SerialEM is also available on all four Krios microscopes to trained users who can operate SerialEM independently.
All Krios microscopes are equipped with Volta style phase plates, greatly boosting low-resolution contrast, facilitating cryo-EM on small proteins and cryo-ET applications.
The fifth Krios is a dedicated microscope for use by commercial clients. As part of eBIC for Industry, it provides an important resource for structure-based drug discovery, for antibody and vaccine research, and to progress the study of nanotechnologies and nanomedicines.
Click on the buttons below for further details.
Benefits for structural biology
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