The Diamond Synchrotron Service Industry Team

Synchrotron Services for Industrial Scientists

Welcome to the Industrial Liaison Office. We are here to help you with all aspects of your work with Diamond.

To find out more about how we can help with your project, please select from the following options:

Featured Case Studies

Mechanical Properties of Bacteria

The Problem profilephoto

Antibiotic resistance is an increasingly serious threat to global public health that requires action across all government sectors and society. There are high proportions of antibiotic resistance in bacteria that cause common infections, for example urinary tract infections, and it is patients with these infections caused by drug-resistant bacteria that are generally at increased risk of worse clinical outcomes and death. These patients consume more health-care resources than patients infected with the same bacteria that are drug-resistant. Developing new treatments to tackle this worldwide problem is therefore of paramount importance.

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Tackling antibiotic resistance

The Problem profilephoto

Respiratory infections are one of the biggest killers in the western world, and pneumococcal infections can range from mild to potentially deadly. Children and the elderly are most at risk, as well as those with compromised immune systems. There are approximately 90 distinct pneumococcal serotypes and, although not all cause disease, this makes treatment challenging. An effective conjugate vaccine has been available since 2001, however there has been a rise in antibiotic resistance in serotypes not covered by this conjugate vaccine and previously non-infectious serotypes are increasing in virulence. This makes treatment of pneumococcal pneumonia and less severe illnesses such as otitis media more difficult to manage. Therefore finding new approaches to combat pneumococcal disease remains a high priority.

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The ABCs of flu

The Problem profilephoto

Influenza viruses altogether affect 5%-10% of the adult population and 20-30% of children each year. These annual epidemics are estimated to result in about approximately 3 to 5 million cases of severe illness, leading to between 250,000 to 500,000 deaths around the world. Integral to viral replication, polymerases are enzymes that copy the viral genome and produce messenger RNA which is then used to make building blocks for new virus particles.

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Mail-in data collection service for MX at Diamond

The Problem profilephoto

Fragment-based and structure-based drug discovery programmes put a strong emphasis on frequent routine macromolecular crystallography data collection from numerous samples. Other types of projects may only need occasional data collection on a few samples or researchers may need to run an experiment they have not done before. 

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In crystallo fragment screening

The Problem profilephoto

In the past two decades, fragment based drug discovery has emerged as a powerful method to discover and develop new drugs. Such strategy relies on the identification of low molecular weight compounds that bind weakly to a target. The structural information gained on fragment-target complexes provides an excellent starting point for the development of potent and selective drugs.

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The Industrial Liaison Advent Calendar 2016

Pop in every day to open a new window and find out more about Diamond Light Source and the research that takes place here...

Latest News Subscribe to our newsfeed

  • Dec 8, 2016
    Drug discovery goes intracellular

    Drug discovery goes intracellular

    Heptares publish groundbreaking research undertaken at Diamond revealing evidence of a novel binding site on a GPCR CCR9. Read more here....

  • Dec 1, 2016
    Advent Calendar 2016

    Advent Calendar 2016

    Pop in every day to open a new window and find out more about Diamond Light Source and the research that takes place here...

  • Nov 30, 2016
    The nickelate nano-switch

    The nickelate nano-switch

    First observation of conductor-insulator transition

Want to know more?

Please contact us:

Industrial Liaison Office
Tel: +44 (0) 1235 778797
E-mail: industry@diamond.ac.uk

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  • NEW!! Structural Biology Newsletter Issue 5
  • The Evolution of VMXi
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